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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 378746-64-6, Nemonoxacin [inn], Tg-873870, Taigexyn, P94l0pvo94, 7-[(3s,5s)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4-oxoquinoline-3-carboxylic acid
Molecular Formula
C20H25N3O4
Molecular Weight
371.4  g/mol
InChI Key
AVPQPGFLVZTJOR-RYUDHWBXSA-N
FDA UNII
P94L0PVO94

Nemonoxacin
1 2D Structure

Nemonoxacin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-[(3S,5S)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4-oxoquinoline-3-carboxylic acid
2.1.2 InChI
InChI=1S/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1
2.1.3 InChI Key
AVPQPGFLVZTJOR-RYUDHWBXSA-N
2.1.4 Canonical SMILES
CC1CC(CN(C1)C2=C(C3=C(C=C2)C(=O)C(=CN3C4CC4)C(=O)O)OC)N
2.1.5 Isomeric SMILES
C[C@H]1C[C@@H](CN(C1)C2=C(C3=C(C=C2)C(=O)C(=CN3C4CC4)C(=O)O)OC)N
2.2 Other Identifiers
2.2.1 UNII
P94L0PVO94
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Tg 873870

2. Tg-873870

3. Tg873870

2.3.2 Depositor-Supplied Synonyms

1. 378746-64-6

2. Nemonoxacin [inn]

3. Tg-873870

4. Taigexyn

5. P94l0pvo94

6. 7-[(3s,5s)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4-oxoquinoline-3-carboxylic Acid

7. Tg873870

8. 7-((3s,5s)-3-amino-5-methylpiperidin-1-yl)-1-cyclopropyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

9. Unii-p94l0pvo94

10. 7-[(3s,5s)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

11. Starbld0028467

12. Tg 873870

13. Nemonoxacin [who-dd]

14. Schembl1006373

15. Chembl1213456

16. Gtpl10836

17. Dtxsid10958907

18. Tqp0855

19. Chebi:136053

20. Zinc40435195

21. Db06600

22. Hy-14956

23. Cs-0003656

24. Q15425793

25. 3-quinolinecarboxylic Acid, 7-((3s,5s)-3-amino-5-methyl-1-piperidinyl)-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-

26. 7-[(3s,5s)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4- Oxo-1,4-dihydroquinoline-3-carboxylic Acid

2.4 Create Date
2007-02-05
3 Chemical and Physical Properties
Molecular Weight 371.4 g/mol
Molecular Formula C20H25N3O4
XLogP30.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass371.18450629 g/mol
Monoisotopic Mass371.18450629 g/mol
Topological Polar Surface Area96.1 Ų
Heavy Atom Count27
Formal Charge0
Complexity647
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Investigated for use/treatment in bacterial infection and pneumonia.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


5.2 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01M - Quinolone antibacterials

J01MB - Other quinolones

J01MB08 - Nemonoxacin


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ABOUT THIS PAGE

Nemonoxacin Manufacturers

A Nemonoxacin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nemonoxacin, including repackagers and relabelers. The FDA regulates Nemonoxacin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nemonoxacin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Nemonoxacin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Nemonoxacin Suppliers

A Nemonoxacin supplier is an individual or a company that provides Nemonoxacin active pharmaceutical ingredient (API) or Nemonoxacin finished formulations upon request. The Nemonoxacin suppliers may include Nemonoxacin API manufacturers, exporters, distributors and traders.

click here to find a list of Nemonoxacin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Nemonoxacin GMP

Nemonoxacin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Nemonoxacin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nemonoxacin GMP manufacturer or Nemonoxacin GMP API supplier for your needs.

Nemonoxacin CoA

A Nemonoxacin CoA (Certificate of Analysis) is a formal document that attests to Nemonoxacin's compliance with Nemonoxacin specifications and serves as a tool for batch-level quality control.

Nemonoxacin CoA mostly includes findings from lab analyses of a specific batch. For each Nemonoxacin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Nemonoxacin may be tested according to a variety of international standards, such as European Pharmacopoeia (Nemonoxacin EP), Nemonoxacin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nemonoxacin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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