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Chemistry

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Also known as: Neomycin sulfate, 1405-10-3, Neomycin trisulfate hydrate, Akos016010116
Molecular Formula
C23H48N6O17S
Molecular Weight
712.7  g/mol
InChI Key
OIXVKQDWLFHVGR-VTSVPHRWSA-N

Neomycin Sulfate
Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.
1 2D Structure

Neomycin Sulfate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4R,5R)-4-[(3R,4R,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid
2.1.2 InChI
InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13+,14+,15-,16-,17-,18-,19+,20+,21-,22?,23+;/m1./s1
2.1.3 InChI Key
OIXVKQDWLFHVGR-VTSVPHRWSA-N
2.1.4 Canonical SMILES
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O
2.1.5 Isomeric SMILES
C1[C@H]([C@@H]([C@@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@H]([C@H](O3)CO)OC4[C@@H]([C@H]([C@H]([C@@H](O4)CN)O)O)N)O)O)N.OS(=O)(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Neomycin

2. Neomycin Palmitate

3. Neomycin Sulfate

2.2.2 Depositor-Supplied Synonyms

1. Neomycin Sulfate

2. 1405-10-3

3. Neomycin Trisulfate Hydrate

4. Akos016010116

2.3 Create Date
2013-05-31
3 Chemical and Physical Properties
Molecular Weight 712.7 g/mol
Molecular Formula C23H48N6O17S
Hydrogen Bond Donor Count15
Hydrogen Bond Acceptor Count23
Rotatable Bond Count9
Exact Mass712.27966526 g/mol
Monoisotopic Mass712.27966526 g/mol
Topological Polar Surface Area436 Ų
Heavy Atom Count47
Formal Charge0
Complexity953
Isotope Atom Count0
Defined Atom Stereocenter Count18
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameNeomycin sulfate
Drug LabelNeomycin Sulfate Tablets, USP, for oral administration, contain neomycin which is an antibiotic obtained from the metabolic products of the actinomycete Streptomycesfradiae. Structurally, neomycin sulfate may be represented as follows:Chemically, i...
Active IngredientNeomycin sulfate
Dosage FormTablet
RouteOral
Strength500mg
Market StatusPrescription
CompanyOman Pharm Products; Teva; X Gen Pharms

2 of 2  
Drug NameNeomycin sulfate
Drug LabelNeomycin Sulfate Tablets, USP, for oral administration, contain neomycin which is an antibiotic obtained from the metabolic products of the actinomycete Streptomycesfradiae. Structurally, neomycin sulfate may be represented as follows:Chemically, i...
Active IngredientNeomycin sulfate
Dosage FormTablet
RouteOral
Strength500mg
Market StatusPrescription
CompanyOman Pharm Products; Teva; X Gen Pharms

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


Protein Synthesis Inhibitors

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Aminoglycosides [CS]; Aminoglycoside Antibacterial [EPC]

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Rochem International Inc

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Pfizer CentreOne

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DMF Review : N/A

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DMF Number : 13615

Submission : 1998-09-01

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Penick Corp

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R1-CEP 1999-184 - Rev 03
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Chemical
2020-04-21
197
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Certificate Number : R1-CEP 1999-184 - Rev 03

Status : Valid

Issue Date : 2020-04-21

Type : Chemical

Substance Number : 197

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Certificate Number : R1-CEP 2017-006 - Rev 00

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Substance Number : 197

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Certificate Number : R1-CEP 2001-317 - Rev 00

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Substance Number : 197

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Certificate Number : R0-CEP 2022-013 - Rev 01

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Neomycin Sulfate

Registration Number : 217MF10976

Registrant's Address : 235 East 42nd Street, New York, NY 10017

Initial Date of Registration : 2005-11-14

Latest Date of Registration : 2022-06-22

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Neomycin Sulfate

Registration Number : 303MF10156

Registrant's Address : No. 8,Ziyang Road,Dianjun District,Yichang City,HubeiProvince,China

Initial Date of Registration : 2021-10-07

Latest Date of Registration : 2021-10-07

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API Reference Price

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ROAD,"},{"dataSource":"API Import","activeIngredients":"NEOMYCIN SULFATE","year":"2021","qtr":"Q2","strtotime":1620930600,"product":"NEOMYCIN SULFATE (QTY: 4 X 200 MG, PRICE: USD-250\/EACH)(FOC)","address":"106, FIRST FLOOR , ASHOKA BHOOPALCHAMBERS BEGUMPET, S.P. ROAD,","city":"HYDERABAD-A.P.","supplier":"THE U.S PHARMACOPEIAL ","supplierCountry":"INDIA","foreign_port":"WASHINGTON DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0008","unit":"KGS","unitRateFc":"1250000","totalValueFC":"1042.2","currency":"USD","unitRateINR":"95421037.5","date":"14-May-2021","totalValueINR":"76336.83","totalValueInUsd":"1042.2","indian_port":"HYDERABAD AIR","hs_no":"29419090","bill_no":"3945126","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON DULLES I","supplierAddress":"","customerAddress":"106, FIRST FLOOR , ASHOKA BHOOPALCHAMBERS BEGUMPET, S.P. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1636396200,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"N\/A","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"383","totalValueFC":"5828.7","currency":"USD","unitRateINR":"28938.1","date":"09-Nov-2021","totalValueINR":"434071","totalValueInUsd":"5828.7","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29419050","bill_no":"1004426","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"N\/A","supplierAddress":"235 EAST 42ND STEET NEW YORK NY 10017 US","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637346600,"product":"NEOMYCIN SULFATE USP MICR (QTY:9.5KGS,VALUE: USD 5718.05)","address":"PLOT NO.2, MAITHRIVIHAR AMEERPET,","city":"HYDERABAD","supplier":"LETCO MEDICAL","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"EUGIA PHARMA SPECIALITIES ","customerCountry":"INDIA","quantity":"9.50","actualQuantity":"9.5","unit":"KGS","unitRateFc":"601.9","totalValueFC":"6072.3","currency":"USD","unitRateINR":"47601.1","date":"20-Nov-2021","totalValueINR":"452210","totalValueInUsd":"6072.3","indian_port":"HYDERABAD AIR","hs_no":"29419090","bill_no":"6331193","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO.2, MAITHRIVIHAR AMEERPET,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1644517800,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"6.79","actualQuantity":"6.79","unit":"KGS","unitRateFc":"141","totalValueFC":"967.3","currency":"USD","unitRateINR":"10677.8","date":"11-Feb-2022","totalValueINR":"72502.22","totalValueInUsd":"967.3","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7447696","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1644517800,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"6.94","actualQuantity":"6.944","unit":"KGS","unitRateFc":"141","totalValueFC":"989.2","currency":"USD","unitRateINR":"10677.9","date":"11-Feb-2022","totalValueINR":"74147.13","totalValueInUsd":"989.2","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7447696","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1644517800,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"15.40","actualQuantity":"15.404","unit":"KGS","unitRateFc":"141","totalValueFC":"2194.3","currency":"USD","unitRateINR":"10677.8","date":"11-Feb-2022","totalValueINR":"164480.73","totalValueInUsd":"2194.3","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"7447696","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1650652200,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"P. NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR","city":"KUKATPALLY HYDERABAD,TELANGANA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ORBICULAR PHARMACEUTICAL TECHNOLOGIES ","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"10000","totalValueFC":"10225.5","currency":"USD","unitRateINR":"771500","date":"23-Apr-2022","totalValueINR":"771500","totalValueInUsd":"10225.5","indian_port":"HYDERABAD AIR","hs_no":"29419090","bill_no":"8402253","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"P. NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1660242600,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"8.01","actualQuantity":"8.01","unit":"KGS","unitRateFc":"145","totalValueFC":"1171.5","currency":"USD","unitRateINR":"11636.6","date":"12-Aug-2022","totalValueINR":"93209.4","totalValueInUsd":"1171.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"9975419","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1660242600,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"10.31","actualQuantity":"10.306","unit":"KGS","unitRateFc":"145","totalValueFC":"1507.2","currency":"USD","unitRateINR":"11636.6","date":"12-Aug-2022","totalValueINR":"119926.41","totalValueInUsd":"1507.2","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"9975419","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1660329000,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"P. NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR","city":"KUKATPALLY HYDERABAD,TELANGANA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ORBICULAR PHARMACEUTICAL TECHNOLOGIES ","customerCountry":"INDIA","quantity":"1.41","actualQuantity":"1.411","unit":"KGS","unitRateFc":"7228.9","totalValueFC":"10287.5","currency":"USD","unitRateINR":"580120.5","date":"13-Aug-2022","totalValueINR":"818550","totalValueInUsd":"10287.5","indian_port":"HYDERABAD AIR","hs_no":"29419050","bill_no":"2002257","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"P. NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1662057000,"product":"H001249500 NEOMYCIN SULFATE USP MICRONIZED ( TEST LICENCE NUMBER TL\/NZ\/22\/000484 DATED 15.07.2022) ( R & D PURPOSE)","address":"208, OKHLA INDUSTRIAL ESTATE,,PHAS E III","city":"NEW DELHI,DELHI","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"MANKIND PHARMA","customerCountry":"INDIA","quantity":"3.46","actualQuantity":"3.458","unit":"KGS","unitRateFc":"1445.9","totalValueFC":"5019.3","currency":"USD","unitRateINR":"116324.5","date":"02-Sep-2022","totalValueINR":"402250","totalValueInUsd":"5019.3","indian_port":"DELHI AIR","hs_no":"29419050","bill_no":"2268206","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"208, OKHLA INDUSTRIAL ESTATE,,PHAS E III"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1664821800,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.35","actualQuantity":"0.35","unit":"KGS","unitRateFc":"180.2","totalValueFC":"61.6","currency":"USD","unitRateINR":"14486.5","date":"04-Oct-2022","totalValueINR":"5070.27","totalValueInUsd":"61.6","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"2740056","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1664821800,"product":"NEOMYCIN SULFATE USP EP","address":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"26.30","actualQuantity":"26.3","unit":"KGS","unitRateFc":"180.2","totalValueFC":"4630.2","currency":"USD","unitRateINR":"14486.5","date":"04-Oct-2022","totalValueINR":"380994.59","totalValueInUsd":"4630.2","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"2740056","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"803, 8TH FLOOR,,HDIL B WING, KALED ONIA, SAHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1672252200,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"P. NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR","city":"KUKATPALLY HYDERABAD,TELANGANA","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ORBICULAR PHARMACEUTICAL TECHNOLOGIES ","customerCountry":"INDIA","quantity":"1.75","actualQuantity":"1.751","unit":"KGS","unitRateFc":"7190.2","totalValueFC":"12764.7","currency":"USD","unitRateINR":"600739.3","date":"29-Dec-2022","totalValueINR":"1051894.5","totalValueInUsd":"12764.7","indian_port":"HYDERABAD AIR","hs_no":"29419050","bill_no":"3955986","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"P. NO 53, ALEAP INDUSTRIAL ESTATE, ,GAJULARAMARAM BEHIND PRAGATHINAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699381800,"product":"NEOMYCIN SULFATE","address":"11TH FLOOR, LOTUS BUSINESS PARK,","city":"MUMBAI,MAHARASHTRA","supplier":"JIANGSU GUOTAI GUOMIAN ","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"MARKSANS PHARMA","customerCountry":"INDIA","quantity":"23.04","actualQuantity":"23.04","unit":"KGS","unitRateFc":"260","totalValueFC":"6053.6","currency":"USD","unitRateINR":"21879","date":"08-Nov-2023","totalValueINR":"504092.16","totalValueInUsd":"6053.6","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"8682459","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"19-21\/F, GUOTAI BLDG. RENMIN ROAD(M), ZHANGJIAGANG CITY, JIANGSU ChinaSDNF China","customerAddress":"11TH FLOOR, LOTUS BUSINESS PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699381800,"product":"NEOMYCIN SULFATE (FOC- FREE SAMPLE 25G X 3 LOTS = 75GMS)","address":"11TH FLOOR, LOTUS BUSINESS PARK,","city":"MUMBAI,MAHARASHTRA","supplier":"JIANGSU GUOTAI GUOMIAN ","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"MARKSANS PHARMA","customerCountry":"INDIA","quantity":"0.08","actualQuantity":"0.075","unit":"KGS","unitRateFc":"260","totalValueFC":"19.7","currency":"USD","unitRateINR":"21879.1","date":"08-Nov-2023","totalValueINR":"1640.93","totalValueInUsd":"19.7","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"8682459","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"19-21\/F, GUOTAI BLDG. RENMIN ROAD(M), ZHANGJIAGANG CITY, JIANGSU ChinaSDNF China","customerAddress":"11TH FLOOR, LOTUS BUSINESS PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725820200,"product":"NEOMYCIN SULFATE USP MICRONIZED","address":"H NO.141, SILPA BRINDAVAN,","city":"KUKATPALLY, HYDERABAD, AP.","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"CHICAGO O\\'HARE INT\\'L","customer":"ORBICULAR PHARMACEUTICAL TECHNOLOGIES ","customerCountry":"INDIA","quantity":"2.02","actualQuantity":"2.024","unit":"KGS","unitRateFc":"3021.5","totalValueFC":"6265.4","currency":"USD","unitRateINR":"259410.6","date":"09-Sep-2024","totalValueINR":"525047.02","totalValueInUsd":"6265.4","indian_port":"Hyderabad Air","hs_no":"29419090","bill_no":"5508154","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"CHICAGO O\\'HARE INT\\'L","supplierAddress":"66 Hudson Boulevard East NEW YORK N Y 10001-2192 UNITED STATES SDNF United States","customerAddress":"H NO.141, SILPA BRINDAVAN,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728930600,"product":"NEOMYCIN SULFATE USP MICRONIZED NEOMYCIN SULFATE USP MICRONIZED","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"PFIZER INC","supplierCountry":"UNITED STATES","foreign_port":"ORADEL","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"11.00","actualQuantity":"11","unit":"KGS","unitRateFc":"414","totalValueFC":"4598.6","currency":"USD","unitRateINR":"35127.9","date":"15-Oct-2024","totalValueINR":"386406.9","totalValueInUsd":"4598.6","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29419090","bill_no":"6134108","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"ORADEL","supplierAddress":"66 HUDSON BOULEVARD EAST NEW YORK NY 1001-2192 SDNF US","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"}]
12-Jan-2021
15-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

FDA Orange Book

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01

ALLERGAN

U.S.A
arrow
CPHI Middle east
Not Confirmed

NEOMYCIN SULFATE; POLYMYXIN B SULFATE; PREDNISOLONE ACETATE

Brand Name : POLY-PRED

Dosage Form : SUSPENSION/DROPS;OPHTHALMIC

Dosage Strength : EQ 0.35% BASE;10,000 UNITS/ML;0.5%

Approval Date : 1982-01-01

Application Number : 50081

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

Abbvie CB

02

WATSON LABS

Ireland
CPHI Middle east
Not Confirmed
arrow

WATSON LABS

Ireland
arrow
CPHI Middle east
Not Confirmed

HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE

Brand Name : OTOCORT

Dosage Form : SOLUTION/DROPS;OTIC

Dosage Strength : 1%;EQ 3.5MG BASE/ML;10,000 UNITS/ML

Approval Date : 1982-01-01

Application Number : 60730

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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03

WATSON LABS

Ireland
CPHI Middle east
Not Confirmed
arrow

WATSON LABS

Ireland
arrow
CPHI Middle east
Not Confirmed

NEOMYCIN SULFATE; POLYMYXIN B SULFATE

Brand Name : NEOMYCIN AND POLYMYXIN B SULFATE

Dosage Form : SOLUTION;IRRIGATION

Dosage Strength : EQ 40MG BASE/ML;200,000 UNITS/ML

Approval Date : 1986-04-08

Application Number : 62664

RX/OTC/DISCN : RX

RLD : No

TE Code : AT

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04

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

NEOMYCIN SULFATE

Brand Name : NEOMYCIN SULFATE

Dosage Form : TABLET;ORAL

Dosage Strength : 500MG

Approval Date : 2016-06-10

Application Number : 204435

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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05

HARROW EYE

U.S.A
CPHI Middle east
Not Confirmed
arrow

HARROW EYE

U.S.A
arrow
CPHI Middle east
Not Confirmed

DEXAMETHASONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE

Brand Name : MAXITROL

Dosage Form : SUSPENSION/DROPS;OPHTHALMIC

Dosage Strength : 0.1%;EQ 3.5MG BASE/ML;10,000 UNITS/ML

Approval Date : 1982-01-01

Application Number : 50023

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AT

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06

PFIZER

U.S.A
CPHI Middle east
Not Confirmed
arrow

PFIZER

U.S.A
arrow
CPHI Middle east
Not Confirmed

NEOMYCIN SULFATE

Brand Name : NEOBIOTIC

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 350MG BASE

Approval Date : 1982-01-01

Application Number : 60475

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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07

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

HYDROCORTISONE ACETATE; NEOMYCIN SULFATE

Brand Name : NEO-CORTEF

Dosage Form : SUSPENSION/DROPS;OPHTHALMIC

Dosage Strength : 1.5%;EQ 3.5MG BASE/ML

Approval Date : 1982-01-01

Application Number : 60612

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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08

PHARMADERM

U.S.A
CPHI Middle east
Not Confirmed
arrow

PHARMADERM

U.S.A
arrow
CPHI Middle east
Not Confirmed

NEOMYCIN SULFATE; TRIAMCINOLONE ACETONIDE

Brand Name : NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE

Dosage Form : CREAM;TOPICAL

Dosage Strength : EQ 3.5MG BASE/GM;0.1%

Approval Date : 1986-07-21

Application Number : 62595

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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09

ROXANE

U.S.A
CPHI Middle east
Not Confirmed
arrow

ROXANE

U.S.A
arrow
CPHI Middle east
Not Confirmed

NEOMYCIN SULFATE

Brand Name : NEOMYCIN SULFATE

Dosage Form : TABLET;ORAL

Dosage Strength : 500MG

Approval Date : 1982-01-01

Application Number : 62173

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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10

SANDOZ

Switzerland
CPHI Middle east
Not Confirmed
arrow

SANDOZ

Switzerland
arrow
CPHI Middle east
Not Confirmed

HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE

Brand Name : NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE

Dosage Form : SOLUTION/DROPS;OTIC

Dosage Strength : 1%;EQ 3.5MG BASE/ML;10,000 UNITS/ML

Approval Date : 1983-08-25

Application Number : 62423

RX/OTC/DISCN : RX

RLD : No

TE Code : AT

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Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Europe

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01

CPHI Middle east
Not Confirmed
arrow
arrow
CPHI Middle east
Not Confirmed

Dexamethasone; Neomycin Sulfate; Polymyxin B

Brand Name :

Dosage Form : EYE AND EAR DROPS

Dosage Strength : 1MG; 3.5MG; 6.000IU

Packaging : 5 Ml/Bottle

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Turkey

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02

TEOFARMA Srl

Country
CPHI Middle east
Not Confirmed
arrow

TEOFARMA Srl

Country
arrow
CPHI Middle east
Not Confirmed

Halcinonide; Neomycin Sulfate

Brand Name : Halciderm Combi

Dosage Form :

Dosage Strength : Cream Derm 30 G 0,1 % + 0,37 %  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

ALFA INTES (IND.TER.SPLENDORE)

Country
CPHI Middle east
Not Confirmed
arrow

ALFA INTES (IND.TER.SPLENDORE)

Country
arrow
CPHI Middle east
Not Confirmed

Dexamethasone Isonicotinate; Neomycin Sulfate

Brand Name : Desalfa

Dosage Form :

Dosage Strength : Gtt Orl 10 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

TEOFARMA Srl

Country
CPHI Middle east
Not Confirmed
arrow

TEOFARMA Srl

Country
arrow
CPHI Middle east
Not Confirmed

Hydrocortisone; Polymyxin B; Neomycin Sulfate; Lidocaine

Brand Name : Mixotone

Dosage Form :

Dosage Strength : Gtt Oto 1Vial+ 1Vial Solv 10 Ml  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Canada

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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : NEO-TETRAMED

Dosage Form : POWDER FOR SOLUTION

Dosage Strength : 200MG/G

Packaging : 400G/2.5KG/10KG

Approval Date :

Application Number : 1976338

Regulatory Info : Prescription

Registration Country : Canada

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02

Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : NEO-CHLOR

Dosage Form : POWDER FOR SOLUTION

Dosage Strength : 20G/100G

Packaging : 100G/400G/10KG

Approval Date :

Application Number : 527335

Regulatory Info : Prescription

Registration Country : Canada

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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : NEOPRO 325

Dosage Form : POWDER FOR SOLUTION

Dosage Strength : 81.25G/100G

Packaging :

Approval Date :

Application Number : 2530619

Regulatory Info : Prescription

Registration Country : Canada

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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : NEO-TETRAPRO

Dosage Form : POWDER FOR SOLUTION

Dosage Strength : 200MG/G

Packaging :

Approval Date :

Application Number : 2530368

Regulatory Info : Prescription

Registration Country : Canada

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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : SCOUR SUSPENSION

Dosage Form : SUSPENSION

Dosage Strength : 28.6MG/ML

Packaging : 240/250/400/500ML

Approval Date :

Application Number : 274895

Regulatory Info : Prescription

Registration Country : Canada

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06

Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : NEO-TERRAMYCIN 50/50

Dosage Form : DRUG PREMIX

Dosage Strength : 110G/Kg

Packaging : 25KG

Approval Date :

Application Number : 2325098

Regulatory Info : Prescription

Registration Country : Canada

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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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NEOMYCIN SULFATE

Brand Name : ORIDERMYL

Dosage Form : OINTMENT

Dosage Strength : 3500UNIT/G

Packaging : 10G/30G

Approval Date :

Application Number : 2364166

Regulatory Info : Prescription

Registration Country : Canada

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG ...DOSAGE - OINTMENT;OPHTHALMIC - 0.1%;EQ 3.5MG BASE/GM;10,000 UNITS/GM

USFDA APPLICATION NUMBER - 50065

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DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;E...DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50168

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DOSAGE - CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/G...DOSAGE - CREAM;TOPICAL - 0.5%;EQ 3.5MG BASE/GM;10,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50218

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DOSAGE - SUSPENSION/DROPS;OTIC - EQ 3MG BASE/...DOSAGE - SUSPENSION/DROPS;OTIC - EQ 3MG BASE/ML;10MG/ML;EQ 3.3MG BASE/ML;0.5MG/ML

USFDA APPLICATION NUMBER - 50356

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DOSAGE - OINTMENT;OPHTHALMIC - EQ 400 UNITS/G...DOSAGE - OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

USFDA APPLICATION NUMBER - 50417

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