Find Netarsudil Mesylate manufacturers, exporters & distributors on PharmaCompass

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ACTIVE PHARMA INGREDIENTS

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JDMF

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Chemistry

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Also known as: 1422144-42-0, Ar-13324 mesylate, Netarsudil dimesylate, Ar-13324 (mesylate), Netarsudil mesilate, Netarsudil mesylate [usan]
Molecular Formula
C30H35N3O9S2
Molecular Weight
645.7  g/mol
InChI Key
QQDRLKRHJOAQDC-FBHGDYMESA-N
FDA UNII
VL756B1K0U

Netarsudil Mesylate
1 2D Structure

Netarsudil Mesylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate;methanesulfonic acid
2.1.2 InChI
InChI=1S/C28H27N3O3.2CH4O3S/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24;2*1-5(2,3)4/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32);2*1H3,(H,2,3,4)/t26-;;/m1../s1
2.1.3 InChI Key
QQDRLKRHJOAQDC-FBHGDYMESA-N
2.1.4 Canonical SMILES
CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)C(CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.CS(=O)(=O)O.CS(=O)(=O)O
2.1.5 Isomeric SMILES
CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)[C@@H](CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.CS(=O)(=O)O.CS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
VL756B1K0U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ar-13324

2. Netarsudil

2.3.2 Depositor-Supplied Synonyms

1. 1422144-42-0

2. Ar-13324 Mesylate

3. Netarsudil Dimesylate

4. Ar-13324 (mesylate)

5. Netarsudil Mesilate

6. Netarsudil Mesylate [usan]

7. Ar-13324

8. Vl756b1k0u

9. Netarsudil Mesylate (usan)

10. (4-((1s)-1-(aminomethyl)-2-(isoquinolin-6-ylamino)-2-oxoethyl)phenyl)methyl 2,4-dimethylbenzoate, Dimethanesulfonate

11. [4-[(2s)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate;methanesulfonic Acid

12. Benzoic Acid, 2,4-dimethyl-, (4-((1s)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl)phenyl)methyl Ester, Methanesulfonate (1:2)

13. (s)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate Dimethanesulfonate

14. Unii-vl756b1k0u

15. Rhopressa (tn)

16. Netarsudil(mesylate)

17. Chembl4594251

18. Schembl16037872

19. Dtxsid301027773

20. Netarsudil Dimesylate [mi]

21. Bcp24703

22. Ex-a2451

23. Xgc14442

24. Hy-12798a

25. Netarsudil Mesilate [who-dd]

26. Cs-4515

27. Netarsudil Mesylate [orange Book]

28. Ac-31225

29. Ar-13324 Mesylate; Netarsudil Mesylate

30. Netarsudil Dimesylate [orange Book]

31. C72658

32. D11031

33. Rocklatan Component Netarsudil Dimesylate

34. Netarsudil Dimesylate Component Of Rocklatan

35. Q27291880

2.4 Create Date
2015-02-13
3 Chemical and Physical Properties
Molecular Weight 645.7 g/mol
Molecular Formula C30H35N3O9S2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count11
Rotatable Bond Count8
Exact Mass645.18147205 g/mol
Monoisotopic Mass645.18147205 g/mol
Topological Polar Surface Area220 Ų
Heavy Atom Count44
Formal Charge0
Complexity770
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3

USDMF

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Gland Pharma Ltd

India

USDMF

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GDUFA

DMF Review : Complete

Rev. Date : 2021-09-29

Pay. Date : 2021-08-16

DMF Number : 35954

Submission : 2021-06-17

Status : Active

Type : II

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Micro Labs Ltd

India

USDMF

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GDUFA

DMF Review : Complete

Rev. Date : 2021-09-21

Pay. Date : 2021-08-06

DMF Number : 36043

Submission : 2021-07-27

Status : Active

Type : II

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NDC API

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NETARSUDIL MESYLATE

NDC Package Code : 70727-324

Start Marketing Date : 2017-12-18

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1g/g)

Marketing Category : BULK INGREDIENT

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NETARSUDIL MESYLATE

NDC Package Code : 70600-026

Start Marketing Date : 2021-03-15

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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NETARSUDIL MESYLATE

NDC Package Code : 12817-815

Start Marketing Date : 2024-12-12

End Marketing Date : 2025-12-31

Dosage Form (Strength) : POWDER (100kg/100kg)

Marketing Category : BULK INGREDIENT

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Listed Suppliers

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Netarsudil Mesylate

About the Company : Maithri Drugs is one of India's fast-growing pharmaceutical companies. Maithri's strategic focus is on active pharma ingredients (APIs). The company is widely recognized for its ex...

Maithri Drugs is one of India's fast-growing pharmaceutical companies. Maithri's strategic focus is on active pharma ingredients (APIs). The company is widely recognized for its excellent research & development and aggressive growth strategies. Our 32 US DMFs and 9 CEPs in a short span attest to our R&D excellence. Maithri's manufacturing facility is located in Hyderabad. This facility is audited and approved by the US FDA. In addition, our facility is certified according to the standards of DCGI, WHO GMP, and ISO 9001:2015 We have a portfolio of 65 products and are continually expanding.
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Netarsudil Mesylate

About the Company : Micro Labs Limited is a diversified healthcare company with cutting-edge R&D, advanced manufacturing facilities, and a strong distribution network. It ranks among India's top pharm...

Micro Labs Limited is a diversified healthcare company with cutting-edge R&D, advanced manufacturing facilities, and a strong distribution network. It ranks among India's top pharmaceutical companies, with a leading presence in cardiology, diabetology, anti-infectives, ophthalmology, and pain management. The company is known for its high-quality medicines, including the popular fever management brand, Dolo. Micro Labs continues to grow through innovation, research, and global expansion, delivering healthcare solutions that meet international standards.
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API Reference Price

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26-Mar-2021
22-Oct-2024
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ABOUT THIS PAGE

Looking for 1422144-42-0 / Netarsudil Mesylate API manufacturers, exporters & distributors?

Netarsudil Mesylate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Netarsudil Mesylate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Netarsudil Mesylate manufacturer or Netarsudil Mesylate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Netarsudil Mesylate manufacturer or Netarsudil Mesylate supplier.

PharmaCompass also assists you with knowing the Netarsudil Mesylate API Price utilized in the formulation of products. Netarsudil Mesylate API Price is not always fixed or binding as the Netarsudil Mesylate Price is obtained through a variety of data sources. The Netarsudil Mesylate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Netarsudil Mesylate

Synonyms

1422144-42-0, Ar-13324 mesylate, Netarsudil dimesylate, Ar-13324 (mesylate), Netarsudil mesilate, Netarsudil mesylate [usan]

Cas Number

1422144-42-0

Unique Ingredient Identifier (UNII)

VL756B1K0U

Netarsudil Mesylate Manufacturers

A Netarsudil Mesylate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Netarsudil Mesylate, including repackagers and relabelers. The FDA regulates Netarsudil Mesylate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Netarsudil Mesylate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Netarsudil Mesylate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Netarsudil Mesylate Suppliers

A Netarsudil Mesylate supplier is an individual or a company that provides Netarsudil Mesylate active pharmaceutical ingredient (API) or Netarsudil Mesylate finished formulations upon request. The Netarsudil Mesylate suppliers may include Netarsudil Mesylate API manufacturers, exporters, distributors and traders.

click here to find a list of Netarsudil Mesylate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Netarsudil Mesylate USDMF

A Netarsudil Mesylate DMF (Drug Master File) is a document detailing the whole manufacturing process of Netarsudil Mesylate active pharmaceutical ingredient (API) in detail. Different forms of Netarsudil Mesylate DMFs exist exist since differing nations have different regulations, such as Netarsudil Mesylate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Netarsudil Mesylate DMF submitted to regulatory agencies in the US is known as a USDMF. Netarsudil Mesylate USDMF includes data on Netarsudil Mesylate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Netarsudil Mesylate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Netarsudil Mesylate suppliers with USDMF on PharmaCompass.

Netarsudil Mesylate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Netarsudil Mesylate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Netarsudil Mesylate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Netarsudil Mesylate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Netarsudil Mesylate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Netarsudil Mesylate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Netarsudil Mesylate suppliers with NDC on PharmaCompass.

Netarsudil Mesylate GMP

Netarsudil Mesylate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Netarsudil Mesylate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Netarsudil Mesylate GMP manufacturer or Netarsudil Mesylate GMP API supplier for your needs.

Netarsudil Mesylate CoA

A Netarsudil Mesylate CoA (Certificate of Analysis) is a formal document that attests to Netarsudil Mesylate's compliance with Netarsudil Mesylate specifications and serves as a tool for batch-level quality control.

Netarsudil Mesylate CoA mostly includes findings from lab analyses of a specific batch. For each Netarsudil Mesylate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Netarsudil Mesylate may be tested according to a variety of international standards, such as European Pharmacopoeia (Netarsudil Mesylate EP), Netarsudil Mesylate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Netarsudil Mesylate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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