Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 3 USDMF

3 API Suppliers
3 USDMF

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

2INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 161600-01-7, Mcc-555, Isaglitazone, Rwj-241947, Mcc 555, Pgx-510

Molecular Formula

C₂₁H₁₆FNO₃S

Molecular Weight

381.4 g/mol

InChI Key

PKWDZWYVIHVNKS-UHFFFAOYSA-N

FDA UNII

QOV2JZ647A

Netoglitazone is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Netoglitazone exerts both peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist activity. Netoglitazone decreases bone formation and increases marrow adipocyte formation in vivo.

1 2D Structure

Netoglitazone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione

2.1.2 InChI

InChI=1S/C21H16FNO3S/c22-18-4-2-1-3-16(18)12-26-17-8-7-14-9-13(5-6-15(14)11-17)10-19-20(24)23-21(25)27-19/h1-9,11,19H,10,12H2,(H,23,24,25)

2.1.3 InChI Key

PKWDZWYVIHVNKS-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=CC=C(C(=C1)COC2=CC3=C(C=C2)C=C(C=C3)CC4C(=O)NC(=O)S4)F

2.2 Other Identifiers

2.2.1 UNII

QOV2JZ647A

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2,4-thiazolidinedione, 5-((6-((2-fluorophenyl)methoxy)-2-naphthalenyl)methyl)-

2. 5-((6-((2-fluorophenyl)methoxy)-2-naphthalenyl)methyl)-2,4-thiazolidinedione

3. Isaglitazone

4. Mcc 555

5. Mcc-555

6. Pgx 510

7. Pgx-510

8. Rwj-241947

9. Rwj241947

2.3.2 Depositor-Supplied Synonyms

1. 161600-01-7

2. Mcc-555

3. Isaglitazone

4. Rwj-241947

5. Mcc 555

6. Pgx-510

7. Qov2jz647a

8. 5-((6-((2-fluorobenzyl)oxy)naphthalen-2-yl)methyl)thiazolidine-2,4-dione

9. 5-((6-((2-fluorophenyl)methoxy)-2-naphthalenyl)methyl)-2,4-thiazolidinedione

10. 5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione

11. 2,4-thiazolidinedione, 5-((6-((2-fluorophenyl)methoxy)-2-naphthalenyl)methyl)-

12. Netoglitazone [usan]

13. (5rs)-5-((6-((2-fluorobenzyl)oxy)-2-naphthyl)methyl)thiazolidine-2,4-dione

14. Unii-qov2jz647a

15. Netoglitazone (usan/inn)

16. Netoglitazone [usan:inn]

17. Netoglitazone [inn]

18. Mls006010812

19. Chembl93747

20. Schembl142658

21. Gtpl2707

22. Mcc555

23. Dtxsid5043712

24. Db09199

25. 5-({6-[(2-fluorobenzyl)oxy]naphthalen-2-yl}methyl)-1,3-thiazolidine-2,4-dione

26. Ncgc00370742-06

27. As-16475

28. Smr004701744

29. Hy-100428

30. Cs-0018884

31. D05150

32. A899346

33. Q6999822

2.4 Create Date

2005-08-09

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₁₆FNO₃S
Molecular Weight	381.4 g/mol
XLogP3	4.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	381.08349271 g/mol
Monoisotopic Mass	381.08349271 g/mol
Topological Polar Surface Area	80.7 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	560
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1