Find Nifekalant Hydrochloride manufacturers, exporters & distributors on PharmaCompass

Nifekalant Hydrochloride

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 3 JDMF

3 API Suppliers
3 JDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 130656-51-8, Nifekalant, Nifekalant hcl, Ms 551, Ms-551, 130636-43-0

Molecular Formula

C₁₉H₂₈ClN₅O₅

Molecular Weight

441.9 g/mol

InChI Key

YPVGGQKNWAKOPX-UHFFFAOYSA-N

FDA UNII

TPP5R0MDQS

1 2D Structure

Nifekalant Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethylpyrimidine-2,4-dione;hydrochloride

2.1.2 InChI

InChI=1S/C19H27N5O5.ClH/c1-21-17(14-18(26)22(2)19(21)27)20-9-11-23(12-13-25)10-3-4-15-5-7-16(8-6-15)24(28)29;/h5-8,14,20,25H,3-4,9-13H2,1-2H3;1H

2.1.3 InChI Key

YPVGGQKNWAKOPX-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1C(=CC(=O)N(C1=O)C)NCCN(CCCC2=CC=C(C=C2)[N+](=O)[O-])CCO.Cl

2.2 Other Identifiers

2.2.1 UNII

TPP5R0MDQS

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1,3-dimethyl-6-((2-(n-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino)ethylamino)-2,4(1h),3h)-pyrimidinedione Hydrochloride

2. Ms 551

3. Ms-551

4. Nifekalant

2.3.2 Depositor-Supplied Synonyms

1. 130656-51-8

2. Nifekalant

3. Nifekalant Hcl

4. Ms 551

5. Ms-551

6. 130636-43-0

7. Tpp5r0mdqs

8. Shinbit

9. Dsstox_cid_26495

10. Dsstox_rid_81665

11. Dsstox_gsid_46495

12. 6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethylpyrimidine-2,4-dione;hydrochloride

13. Nifekalant Hydrochloride (jan)

14. Smr000466369

15. Cas-130636-43-0

16. Unii-tpp5r0mdqs

17. Ncgc00164637-01

18. Shinbit (tn)

19. 1,3-dimethyl-6-((2-(n-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino)ethylamino)-2,4(1h),3h)-pyrimidinedione Hcl

20. Mls000759497

21. Mls001401449

22. Mls006010783

23. Schembl243693

24. Chembl553090

25. Dtxsid7048374

26. Chebi:31909

27. Hy-b0772a

28. 2,4(1h,3h)-dione Hydrochloride

29. Bcp12511

30. Tox21_112254

31. Nifekalant Hydrochloride [mi]

32. Akos015900502

33. Tox21_112254_1

34. Ac-3499

35. Ccg-100897

36. Nc00147

37. Ncgc00164637-02

38. Nifekalant Hydrochloride [who-dd]

39. 2,4(1h,3h)-pyrimidinedione, 6-((2-((2-hydroxyethyl)(3-(4-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyl-, Monohydrochloride

40. Amino)ethylamino)-1,3-dimethylpyrimidine-

41. Nifekalant Hydrochloride, >=98% (hplc)

42. Db-041979

43. Cs-0014293

44. Ft-0631132

45. D01856

46. 656n518

47. A806121

48. 6-(2-((2-hydroxyethyl)(3-(4-nitrophenyl)propyl)

49. J-005843

50. Q27290131

51. Benzoic Acid,4-(2-aminoethyl)-,1,1-dimethylethyl Ester

52. 6-(2-((2-hydroxyethyl)(3-(4-nitrophenyl)propyl)amino)ethylamino)-1,3-dimethylpyrimidine-2,4(1h,3h)-dione Hydrochloride

53. 6-(2-(2-hydroxyethyl-(3-(4-nitrophenyl)propyl)amino)ethyl Amino)-1,3-dimethylpyrimidine-2,4-dione Hcl

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₈ClN₅O₅
Molecular Weight	441.9 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	10
Exact Mass	441.1778967 g/mol
Monoisotopic Mass	441.1778967 g/mol
Topological Polar Surface Area	122 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	613
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Arrhythmia Agents

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

API SUPPLIERS