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Chemistry

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Also known as: 4936-47-4, Methylmercadone, Omnes, Macmiror, Magmilor, Polmiror
Molecular Formula
C10H11N3O5S
Molecular Weight
285.28  g/mol
InChI Key
SRQKTCXJCCHINN-NYYWCZLTSA-N
FDA UNII
U60U6P08SP

Nifuratel
Local antiprotozoal and antifungal agent that may also be given orally.
1 2D Structure

Nifuratel

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-(methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
2.1.2 InChI
InChI=1S/C10H11N3O5S/c1-19-6-8-5-12(10(14)18-8)11-4-7-2-3-9(17-7)13(15)16/h2-4,8H,5-6H2,1H3/b11-4+
2.1.3 InChI Key
SRQKTCXJCCHINN-NYYWCZLTSA-N
2.1.4 Canonical SMILES
CSCC1CN(C(=O)O1)N=CC2=CC=C(O2)[N+](=O)[O-]
2.1.5 Isomeric SMILES
CSCC1CN(C(=O)O1)/N=C/C2=CC=C(O2)[N+](=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
U60U6P08SP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Inimur

2. Macmiror

3. Methylmercadone

4. Metilmercadon

5. Thiodinon

2.3.2 Depositor-Supplied Synonyms

1. 4936-47-4

2. Methylmercadone

3. Omnes

4. Macmiror

5. Magmilor

6. Polmiror

7. Tydantil

8. Inimur

9. U60u6p08sp

10. Sap-113

11. Nifuratel (usan)

12. 2-oxazolidinone,5-[(methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-

13. Nf-113

14. Sap 113

15. Nifuratel [usan]

16. Nf 113

17. 5-((methylthio)methyl)-3-((5-nitrofurfurylidene)amino)-2-oxazolidinone

18. 5-[(methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone

19. 5-(methylsulfanylmethyl)-3-[(e)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one

20. Nifuratelum

21. 2-oxazolidinone, 5-((methylthio)methyl)-3-(((5-nitro-2-furanyl)methylene)amino)-

22. Nifuratelum [inn-latin]

23. Unii-u60u6p08sp

24. Nifuratel [usan:inn:ban]

25. 5-((methylthio)methyl)-3-(((5-nitro-2-furanyl)methylene)amino)-2-oxazolidinone

26. Macmiror; Magmilor

27. Macmiror (tn)

28. Einecs 225-576-2

29. Brn 0842878

30. Nifuratel [inn]

31. Nifuratel [mi]

32. Nifuratel [mart.]

33. Nifuratel [who-dd]

34. Schembl153098

35. Schembl365913

36. Chembl514315

37. Chebi:135180

38. Hy-a0059

39. Mfcd00057257

40. S3966

41. 5-(methylmercaptomethyl)-3-(5-nitro-2-furfurylidenamino)-2-oxazolidinone

42. Akos015904955

43. L'n-(5-nitro-2-furfurilidene)-3-amino-5-metilmercaptometil-2-ossazolidinone

44. Ccg-267320

45. Cs-1635

46. Db13724

47. L'n-(5-nitro-2-furfurilidene)-3-amino-5-metilmercaptometil-2-ossazolidinone [italian]

48. Nifuratel 100 Microg/ml In Acetonitrile

49. As-13311

50. Ls-13772

51. D01050

52. 936n474

53. J-523607

54. 2-oxazolidinone, 5-((methylthio)methyl)-3-((5-nitrofurfurylidene)amino)-

55. 3-((5-nitro-2-furfurylidene)amino)-5-((methylthio)methyl)-2-oxazolidinone

56. 5-(methylthiomethyl)-3-(5-nitro-2-furfurylidenamino)oxazolidin-2-one

2.4 Create Date
2006-04-28
3 Chemical and Physical Properties
Molecular Weight 285.28 g/mol
Molecular Formula C10H11N3O5S
XLogP30.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass285.04194163 g/mol
Monoisotopic Mass285.04194163 g/mol
Topological Polar Surface Area126 Ų
Heavy Atom Count19
Formal Charge0
Complexity386
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antitrichomonal Agents

Agents used to treat trichomonas infections. (See all compounds classified as Antitrichomonal Agents.)


Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)


4.2 ATC Code

G - Genito urinary system and sex hormones

G01 - Gynecological antiinfectives and antiseptics

G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids

G01AX - Other antiinfectives and antiseptics

G01AX05 - Nifuratel


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ABOUT THIS PAGE

Nifuratel Manufacturers

A Nifuratel manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nifuratel, including repackagers and relabelers. The FDA regulates Nifuratel manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nifuratel API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Nifuratel manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Nifuratel Suppliers

A Nifuratel supplier is an individual or a company that provides Nifuratel active pharmaceutical ingredient (API) or Nifuratel finished formulations upon request. The Nifuratel suppliers may include Nifuratel API manufacturers, exporters, distributors and traders.

click here to find a list of Nifuratel suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Nifuratel GMP

Nifuratel Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Nifuratel GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nifuratel GMP manufacturer or Nifuratel GMP API supplier for your needs.

Nifuratel CoA

A Nifuratel CoA (Certificate of Analysis) is a formal document that attests to Nifuratel's compliance with Nifuratel specifications and serves as a tool for batch-level quality control.

Nifuratel CoA mostly includes findings from lab analyses of a specific batch. For each Nifuratel CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Nifuratel may be tested according to a variety of international standards, such as European Pharmacopoeia (Nifuratel EP), Nifuratel JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nifuratel USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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