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Chemistry

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Also known as: 4936-47-4, Methylmercadone, Omnes, Macmiror, Magmilor, Polmiror
Molecular Formula
C10H11N3O5S
Molecular Weight
285.28  g/mol
InChI Key
SRQKTCXJCCHINN-NYYWCZLTSA-N
FDA UNII
U60U6P08SP

Nifuratel
Local antiprotozoal and antifungal agent that may also be given orally.
1 2D Structure

Nifuratel

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-(methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
2.1.2 InChI
InChI=1S/C10H11N3O5S/c1-19-6-8-5-12(10(14)18-8)11-4-7-2-3-9(17-7)13(15)16/h2-4,8H,5-6H2,1H3/b11-4+
2.1.3 InChI Key
SRQKTCXJCCHINN-NYYWCZLTSA-N
2.1.4 Canonical SMILES
CSCC1CN(C(=O)O1)N=CC2=CC=C(O2)[N+](=O)[O-]
2.1.5 Isomeric SMILES
CSCC1CN(C(=O)O1)/N=C/C2=CC=C(O2)[N+](=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
U60U6P08SP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Inimur

2. Macmiror

3. Methylmercadone

4. Metilmercadon

5. Thiodinon

2.3.2 Depositor-Supplied Synonyms

1. 4936-47-4

2. Methylmercadone

3. Omnes

4. Macmiror

5. Magmilor

6. Polmiror

7. Tydantil

8. Inimur

9. U60u6p08sp

10. Sap-113

11. Nifuratel (usan)

12. 2-oxazolidinone,5-[(methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-

13. Nf-113

14. Sap 113

15. Nifuratel [usan]

16. Nf 113

17. 5-((methylthio)methyl)-3-((5-nitrofurfurylidene)amino)-2-oxazolidinone

18. 5-[(methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone

19. 5-(methylsulfanylmethyl)-3-[(e)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one

20. Nifuratelum

21. 2-oxazolidinone, 5-((methylthio)methyl)-3-(((5-nitro-2-furanyl)methylene)amino)-

22. Nifuratelum [inn-latin]

23. Unii-u60u6p08sp

24. Nifuratel [usan:inn:ban]

25. 5-((methylthio)methyl)-3-(((5-nitro-2-furanyl)methylene)amino)-2-oxazolidinone

26. Macmiror; Magmilor

27. Macmiror (tn)

28. Einecs 225-576-2

29. Brn 0842878

30. Nifuratel [inn]

31. Nifuratel [mi]

32. Nifuratel [mart.]

33. Nifuratel [who-dd]

34. Schembl153098

35. Schembl365913

36. Chembl514315

37. Chebi:135180

38. Hy-a0059

39. Mfcd00057257

40. S3966

41. 5-(methylmercaptomethyl)-3-(5-nitro-2-furfurylidenamino)-2-oxazolidinone

42. Akos015904955

43. L'n-(5-nitro-2-furfurilidene)-3-amino-5-metilmercaptometil-2-ossazolidinone

44. Ccg-267320

45. Cs-1635

46. Db13724

47. L'n-(5-nitro-2-furfurilidene)-3-amino-5-metilmercaptometil-2-ossazolidinone [italian]

48. Nifuratel 100 Microg/ml In Acetonitrile

49. As-13311

50. Ls-13772

51. D01050

52. 936n474

53. J-523607

54. 2-oxazolidinone, 5-((methylthio)methyl)-3-((5-nitrofurfurylidene)amino)-

55. 3-((5-nitro-2-furfurylidene)amino)-5-((methylthio)methyl)-2-oxazolidinone

56. 5-(methylthiomethyl)-3-(5-nitro-2-furfurylidenamino)oxazolidin-2-one

2.4 Create Date
2006-04-28
3 Chemical and Physical Properties
Molecular Weight 285.28 g/mol
Molecular Formula C10H11N3O5S
XLogP30.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass285.04194163 g/mol
Monoisotopic Mass285.04194163 g/mol
Topological Polar Surface Area126 Ų
Heavy Atom Count19
Formal Charge0
Complexity386
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antitrichomonal Agents

Agents used to treat trichomonas infections. (See all compounds classified as Antitrichomonal Agents.)


Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)


4.2 ATC Code

G - Genito urinary system and sex hormones

G01 - Gynecological antiinfectives and antiseptics

G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids

G01AX - Other antiinfectives and antiseptics

G01AX05 - Nifuratel


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