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Chemistry

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Also known as: 51803-78-2, N-(4-nitro-2-phenoxyphenyl)methanesulfonamide, Mesulid, Aulin, Flogovital, Sulidene
Molecular Formula
C13H12N2O5S
Molecular Weight
308.31  g/mol
InChI Key
HYWYRSMBCFDLJT-UHFFFAOYSA-N
FDA UNII
V4TKW1454M

Nimesulide
Nimesulide is a nonsteroidal arylsulfonamide with anti-inflammatory properties. Nimesulide inhibits the cyclooxygenase-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins. Modestly selective for COX-2, this agent binds to the enzyme, thereby inactivating it. Nimesulide may inhibit some carcinogenic COX-2-related carcinogenic effects on xenobiotic metabolism, apoptosis, immune surveillance and angiogenesis (overexpressed COX-2 in tumor epithelial cells enhances production of vascular growth factors and the formation of capillary-like networks). (NCI04)
1 2D Structure

Nimesulide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-(4-nitro-2-phenoxyphenyl)methanesulfonamide
2.1.2 InChI
InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
2.1.3 InChI Key
HYWYRSMBCFDLJT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
2.2 Other Identifiers
2.2.1 UNII
V4TKW1454M
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-nitro-2-phenoxymethanesulfonanilide

2. Antifloxil

3. Aulin

4. Eskaflam

5. Guaxan

6. Lizepat

7. Mesulid

8. Nexen

9. Nimesil

10. R 805

11. R-805

12. Redaflam

2.3.2 Depositor-Supplied Synonyms

1. 51803-78-2

2. N-(4-nitro-2-phenoxyphenyl)methanesulfonamide

3. Mesulid

4. Aulin

5. Flogovital

6. Sulidene

7. Nimed

8. 4-nitro-2-phenoxymethanesulfonanilide

9. R-805

10. Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)-

11. R 805

12. Nisulid

13. 4'-nitro-2'-phenoxymethanesulfonanilide

14. 4-nitro-2-phenoxy-methanesulfonanilide

15. Nsc-758412

16. Chembl56367

17. Mls000069680

18. V4tkw1454m

19. Methanesulfonanilide, 4'-nitro-2'-phenoxy-

20. Chebi:44445

21. Ncgc00015725-02

22. R805

23. Smr000058484

24. Cas-51803-78-2

25. Dsstox_cid_17250

26. Dsstox_rid_79316

27. Dsstox_gsid_37250

28. Antifloxil

29. Nimesulida

30. Nimesulidum

31. Guaxan

32. Nimesulidum [inn-latin]

33. Nimesulida [inn-spanish]

34. Nim

35. Nimesulide [inn:ban]

36. Sr-01000000218

37. Einecs 257-431-4

38. 4'-nitro-2'-phenoxymethansulfonanilid

39. Brn 2421175

40. Unii-v4tkw1454m

41. Aldoron

42. Nimedex

43. Orthobid

44. Ccris 8225

45. Nise Gel

46. Nimesulide,(s)

47. Prestwick_618

48. Mfcd00079470

49. Spectrum_001577

50. Nimesulide [mi]

51. Nimesulide (jan/inn)

52. Nimesulide [inn]

53. Nimesulide [jan]

54. Opera_id_1247

55. Prestwick0_000194

56. Prestwick1_000194

57. Prestwick2_000194

58. Prestwick3_000194

59. Spectrum2_001541

60. Spectrum3_001576

61. Spectrum4_000178

62. Spectrum5_000964

63. Lopac-n-1016

64. N-(4-nitro-2-phenoxy-phenyl)methanesulfonamide

65. Nimesulide [mart.]

66. Nimesulide [who-dd]

67. Lopac0_000855

68. Schembl24882

69. Bspbio_000147

70. Bspbio_001103

71. Bspbio_003112

72. Kbiogr_000443

73. Kbiogr_000695

74. Kbioss_000443

75. Kbioss_002057

76. Mls001148268

77. Divk1c_000693

78. Spectrum1503231

79. Spbio_001382

80. Spbio_002068

81. N-(4-nitro-2-phenoxyphenyl)

82. Bpbio1_000163

83. Gtpl7401

84. Nim-03

85. Dtxsid3037250

86. Nimesulide [ep Impurity]

87. Bcbcmap01_000034

88. Hms502c15

89. Kbio1_000693

90. Kbio2_000443

91. Kbio2_002057

92. Kbio2_003011

93. Kbio2_004625

94. Kbio2_005579

95. Kbio2_007193

96. Kbio3_000825

97. Kbio3_000826

98. Kbio3_002612

99. Nimesulide [ep Monograph]

100. Nimesulide For Peak Identification

101. Ninds_000693

102. Bio2_000382

103. Bio2_000862

104. Hms1362g05

105. Hms1568h09

106. Hms1792g05

107. Hms1922k17

108. Hms1990g05

109. Hms2089b14

110. Hms2095h09

111. Hms2234k19

112. Hms3262l11

113. Hms3269g17

114. Hms3371j19

115. Hms3403g05

116. Hms3414p09

117. Hms3649a04

118. Hms3655d13

119. Hms3678p07

120. Hms3712h09

121. Hms3884c22

122. Pharmakon1600-01503231

123. Bcp10076

124. Hy-b0363

125. Zinc4617749

126. Tox21_110207

127. Tox21_301850

128. Tox21_500855

129. Bdbm50056999

130. Ccg-39319

131. Ei-287

132. Nsc758412

133. S2040

134. Stl018679

135. Akos015897356

136. Tox21_110207_1

137. Ac-4524

138. Db04743

139. Ks-1277

140. Lp00855

141. Nsc 758412

142. Sdccgsbi-0050831.p004

143. Idi1_000693

144. Idi1_002137

145. Ncgc00015725-01

146. Ncgc00015725-03

147. Ncgc00015725-04

148. Ncgc00015725-05

149. Ncgc00015725-06

150. Ncgc00015725-07

151. Ncgc00015725-08

152. Ncgc00015725-09

153. Ncgc00015725-10

154. Ncgc00015725-11

155. Ncgc00015725-12

156. Ncgc00015725-13

157. Ncgc00015725-15

158. Ncgc00015725-16

159. Ncgc00015725-29

160. Ncgc00021842-03

161. Ncgc00021842-04

162. Ncgc00021842-05

163. Ncgc00021842-06

164. Ncgc00021842-07

165. Ncgc00021842-08

166. Ncgc00255661-01

167. Ncgc00261540-01

168. Bn166246

169. Nimesulide 100 Microg/ml In Acetonitrile

170. Sbi-0050831.p003

171. Db-052029

172. Ab00052332

173. Eu-0100855

174. Ft-0630650

175. N0984

176. Sw196785-3

177. D01049

178. D70376

179. N 1016

180. Q20994

181. Ab00052332-16

182. Ab00052332_17

183. Ab00052332_18

184. N-[4-nitro-2-(phenoxy)phenyl]methanesulfonamide

185. 803n782

186. A828786

187. Sr-01000000218-2

188. Sr-01000000218-6

189. Sr-01000000218-7

190. W-105866

191. Brd-k76775527-001-06-2

192. Brd-k76775527-001-18-7

193. Sr-01000000218-11

194. Nimesulide, European Pharmacopoeia (ep) Reference Standard

195. Nimesulide, Pharmaceutical Secondary Standard; Certified Reference Material

196. Nimesulide For Peak Identification, European Pharmacopoeia (ep) Reference Standard

197. 1364966-82-4

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 308.31 g/mol
Molecular Formula C13H12N2O5S
XLogP32.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass308.04669266 g/mol
Monoisotopic Mass308.04669266 g/mol
Topological Polar Surface Area110 Ų
Heavy Atom Count21
Formal Charge0
Complexity450
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Food, gender and advanced age have negligible effects on nimesulide pharmacokinetics.


5.2 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)


5.3 ATC Code

M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AX - Other antiinflammatory and antirheumatic agents, non-steroids

M01AX17 - Nimesulide


M - Musculo-skeletal system

M02 - Topical products for joint and muscular pain

M02A - Topical products for joint and muscular pain

M02AA - Antiinflammatory preparations, non-steroids for topical use

M02AA26 - Nimesulide


5.4 Absorption, Distribution and Excretion

Absorption

Rapidly absorbed following oral administration.


Route of Elimination

Renal (50%), fecal (29%)


5.5 Metabolism/Metabolites

Hepatic. Extensive biotransformation, mainly to 4-hydroxynimesulide (which also appears to be biologically active).


5.6 Biological Half-Life

1.84.7 hours


5.7 Mechanism of Action

The therapeutic effects of Nimesulide are the result of its complete mode of action which targets a number of key mediators of the inflammatory process such as: COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.


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LGM Pharma

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Aarti Drugs Ltd

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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 20813

Submission : 2007-08-28

Status : Inactive

Type : II

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Procos Spa

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Procos Spa

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Submission : 2001-07-24

Status : Inactive

Type : II

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Certificate Number : R1-CEP 2002-046 - Rev 06

Status : Valid

Issue Date : 2019-05-03

Type : Chemical

Substance Number : 1548

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Certificate Number : R1-CEP 2004-117 - Rev 01

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Issue Date : 2015-11-13

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Substance Number : 1548

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Certificate Number : R1-CEP 2010-377 - Rev 02

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Certificate Number : R1-CEP 2001-350 - Rev 02

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Aarti Drugs

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Nimesulide BP/EP

Date of Issue : 2019-09-03

Valid Till : 2022-09-02

Written Confirmation Number : WC-0251

Address of the Firm : Plot No. N-198, MIDC, Tarapur, Boisar, Tal. Palghar, Dist. Thane-401506, Mahrash...

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Nimesulide EP/BP

Date of Issue : 2022-10-27

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Written Confirmation Number : WC-0167

Address of the Firm : Unit No.1, Plot No.187, IInd Phase, GIDC Vapi-396195, Dist-Valsad, India

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Nimesulide BP/EP

Date of Issue : 2020-06-11

Valid Till : 2023-06-10

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Address of the Firm : Unit-2, Plot No.1203, III Phase, GIDC, Vapi-396 195, Dist-Valsad, Gujarat, India

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Date of Issue : 2019-10-22

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Nimesulid

Registrant Name : JDW Pharmaceutical Co., Ltd.

Registration Date : 2021-07-30

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Nimesulid

Registrant Name : Ace Biopharm Co., Ltd.

Registration Date : 2022-04-22

Registration Number : 20220422-209-J-1276

Manufacturer Name : Mangalam Drugs and Organics ...

Manufacturer Address : PLOT NO. 1203, PHASE-III, GIDC, VAPI-396 195, Dist. VALSAD, GUJARAT, INDA.

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OLON S.P.A.

Italy
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NIMESULIDE

NDC Package Code : 17337-0533

Start Marketing Date : 2022-06-07

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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LGM Pharma

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Nimesulide

About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
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Nimesulide

About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.
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Nimesulide

About the Company : Atman Pharmaceuticals is a fully integrated pharmaceutical company that has distinguished itself as a leader in Bulk Drugs (API) marketing both domestically in India and overseas. ...

Atman Pharmaceuticals is a fully integrated pharmaceutical company that has distinguished itself as a leader in Bulk Drugs (API) marketing both domestically in India and overseas. With a heritage spanning over 33 years and vast experience, we have earned a reputation for delivering high-quality and abundant services within the industry. Our emergence as prominent solution providers in the pharmaceutical business underscores our commitment to excellence.
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Nimesulide

About the Company : Bajaj Healthcare Ltd. is a company established in 1993, services various Pharmaceuticals, Nutraceutical and Food industries globally with a spirit of scrupulousness. Bajaj Healt...

Bajaj Healthcare Ltd. is a company established in 1993, services various Pharmaceuticals, Nutraceutical and Food industries globally with a spirit of scrupulousness. Bajaj Healthcare Ltd. have metamorphosed into specialty company and focused on development, manufacturing and supply of Amino Acids, Nutritional Supplements and Active Pharmaceutical Ingredients (API) for Pharmaceutical, Nutraceuticals and Food industries. Bajaj healthcare Ltd. in its shot life span has gained loyalty from national and international customers and our products enjoy good fame in the overseas market.
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05

HELM Portugal

Portugal
Compamed
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HELM Portugal

Portugal
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Compamed
Not Confirmed

Nimesulide

About the Company : HELM Portugal is HELM’s Competence Centre for the marketing of Active Pharmaceutical Ingredients (API). The leading APIs distributed by Helm include Ascorbic Acid pharma Grade (C...

HELM Portugal is HELM’s Competence Centre for the marketing of Active Pharmaceutical Ingredients (API). The leading APIs distributed by Helm include Ascorbic Acid pharma Grade (CEP), Heparin Sodium (CEP holder), Dimetindene Maleate EP. Helm supply high-quality pharmaceuticals and provide a broad range of services on a global scale. Our services include: Logistics and distribution, Sourcing on Demand, Regulatory Affairs and Quality.
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06

Compamed
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Compamed
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Nimesulide

About the Company : Hoventa Pharma is in the business of manufacturing APIs for over three decades.We offer various kinds of services in addition to supplies of APIs, we undertake long-term contracts ...

Hoventa Pharma is in the business of manufacturing APIs for over three decades.We offer various kinds of services in addition to supplies of APIs, we undertake long-term contracts for manufacturing intermediates and development of new Active Pharmaceutical Ingredients as per your requirement. We have a sharp focus on giving value added services to our customers cost effectively. We are supplying APIs to the global pharmaceutical companies in India and abroad since the last 3 decades. Some of our major customers operate in India and export to their products to other countries.
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07

Olon S.p.A

Italy
Compamed
Not Confirmed
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Olon S.p.A

Italy
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Compamed
Not Confirmed

Nimesulide

About the Company : We produce Active Pharmaceutical Ingredients (APIs) providing integrated full-service capabilities. Olon’s ability to develop and manufacture Active Pharmaceutical Ingredients (...

We produce Active Pharmaceutical Ingredients (APIs) providing integrated full-service capabilities. Olon’s ability to develop and manufacture Active Pharmaceutical Ingredients (APIs) in our network of facilities allows clients full access to integrated services resulting in faster production and delivery timelines, with one of the most extensive track records. We rely on synthetic and biological processes both for generic and contract development and the manufacturing market, in a full cGMPs environment, following ICH Q7 compliance.
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08

Compamed
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Nimesulide

About the Company : Pellets Pharma Limited is a fast growing organization established by a team of professionals with over decades of experience in the pharmaceutical industry with specific reference ...

Pellets Pharma Limited is a fast growing organization established by a team of professionals with over decades of experience in the pharmaceutical industry with specific reference to the development and manufacture of various modified release solid oral dosage forms. The company’s forte is the customized development and manufacturing of Modified Release Pellets / Retard Micro Granules of various Active Pharmaceutical Ingredients (APIs) including different combination blends in Ready - To - Fill form. The facility is designed to meet the regulatory requirements inline with the cGMP norms.
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09

Sibbiotech

Russia
Compamed
Not Confirmed
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Sibbiotech

Russia
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Compamed
Not Confirmed

Nimesulide

About the Company : The technology of production of artemisinin and its derivatives is based on the use of cultivation of annual wormwood cells and extraction of artemisinin and artemisinic acid. Qual...

The technology of production of artemisinin and its derivatives is based on the use of cultivation of annual wormwood cells and extraction of artemisinin and artemisinic acid. Quality control is carried out by an independent accredited laboratory of the Koltsovo Biotechnopark, which complies with the norms and rules of the international standard of good manufacturing practice GMP.SIBBIOTECH Industrial Park occupies 3 hectares. The electric capacities of the green electricity of the Novosibirsk hydroelectric power station, centralized gas and water supply and centralized wastewater disposal are available.
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10

Compamed
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Nimesulide

About the Company : Smaart Pharmaceutticals consciously strive for innovation through newer technologies, modern equipment available betterment of life and bring newer products for its customer. Smaa...

Smaart Pharmaceutticals consciously strive for innovation through newer technologies, modern equipment available betterment of life and bring newer products for its customer. Smaart has two state of the art manufacturing blocks. Our registered office is located at Jalgaon; which is our manufacturing facility as well. Geographically Jalgaon falls at North of Maharashtra, in the close vicinity of The famous ancient Buddhist cave temples of Ajanta; which were excavated between the 2d century BC and the 5th century AD.
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API Reference Price

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08-Jan-2021
28-Oct-2024
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Drugs in Development

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Details:

Through the agreement, Angelini Pharma will focus on commercializing Mesulid (nimesulide) in Europe. It is indicated for treating patients suffering from acute pain.


Lead Product(s): Nimesulide

Therapeutic Area: Neurology Brand Name: Mesulid

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Angelini Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement May 24, 2024

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01

Compamed
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Compamed
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Details : Through the agreement, Angelini Pharma will focus on commercializing Mesulid (nimesulide) in Europe. It is indicated for treating patients suffering from acute pain.

Brand Name : Mesulid

Molecule Type : Small molecule

Upfront Cash : Undisclosed

May 24, 2024

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INTERMEDIATES SUPPLIERS

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CAS Number : 51765-51-6

End Use API : Nimesulide

About The Company : Mangalam Drugs & Organics Limited started manufacturing APIs and intermediates in 1977 in Gujarat, India. It has a multi-product manufacturing facility and an i...

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FDF Dossiers

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Compamed
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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTowa Pharma is dedicated to researching, developing, producing, and promoting generic drugs.

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Regulatory Info :

Registration Country : Italy

Nimesulide

Brand Name : NIMESULIDES THINKS

Dosage Form : Granules For Oral Suspension

Dosage Strength : 100 mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

Towa Pharmaceutical

02

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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTowa Pharma is dedicated to researching, developing, producing, and promoting generic drugs.

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Regulatory Info :

Registration Country : Italy

Nimesulide

Brand Name : NIMESULIDES THINKS

Dosage Form : Tablet

Dosage Strength : 100mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

Towa Pharmaceutical

03

Bal Pharma

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

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Regulatory Info : Generic

Registration Country : India

Nimesulide

Brand Name : Monogesic

Dosage Form : Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

BalPharma

04

Bal Pharma

India
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Virtual BoothBal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

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Regulatory Info : Generic

Registration Country : India

Nimesulide

Brand Name : Monogesic

Dosage Form : Gel

Dosage Strength : 10MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

BalPharma

05

Compamed
Not Confirmed
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Nimesulide

Brand Name : Algesil

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 CPR 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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06

Compamed
Not Confirmed
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Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 bust grat 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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07

Compamed
Not Confirmed
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Nimesulide

Brand Name :

Dosage Form : Sachet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Sandoz B2B

Switzerland
Compamed
Not Confirmed
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Sandoz B2B

Switzerland
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Compamed
Not Confirmed

Nimesulide

Brand Name : NIMESULIDE SANDAZ

Dosage Form : Granules For Oral Solution

Dosage Strength : 100 mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Not Confirmed
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Compamed
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Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 CPR 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Nimesulide

Brand Name : Sulidamor

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 CPR 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Europe

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01

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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTowa Pharma is dedicated to researching, developing, producing, and promoting generic drugs.

Flag Japan
Digital Content Digital Content

Regulatory Info :

Registration Country : Italy

Nimesulide

Brand Name : NIMESULIDES THINKS

Dosage Form : Granules For Oral Suspension

Dosage Strength : 100 mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

Towa Pharmaceutical

02

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Compamed
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTowa Pharma is dedicated to researching, developing, producing, and promoting generic drugs.

Flag Japan
Digital Content Digital Content

Regulatory Info :

Registration Country : Italy

Nimesulide

Brand Name : NIMESULIDES THINKS

Dosage Form : Tablet

Dosage Strength : 100mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

Towa Pharmaceutical

03

EG SPA

Italy
Compamed
Not Confirmed
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EG SPA

Italy
arrow
Compamed
Not Confirmed

Nimesulide

Brand Name : NIMESULIDE EG

Dosage Form : Tablets

Dosage Strength : 100 mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

Compamed
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Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 bust grat 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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05

Compamed
Not Confirmed
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Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 bust grat 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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06

RATIOPHARM GMBH

Germany
Compamed
Not Confirmed
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RATIOPHARM GMBH

Germany
arrow
Compamed
Not Confirmed

Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 bust grat 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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07

SANDOZ SPA

Switzerland
Compamed
Not Confirmed
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SANDOZ SPA

Switzerland
arrow
Compamed
Not Confirmed

Nimesulide

Brand Name : NIMESULIDE SANDAZ

Dosage Form : Granules For Oral Solution

Dosage Strength : 100 mg

Packaging : 30 UNITS 100 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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08

GERMED PHARMA Srl

Country
Compamed
Not Confirmed
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GERMED PHARMA Srl

Country
arrow
Compamed
Not Confirmed

Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 bust grat 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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09

BENEDETTI & CO.SpA

Country
Compamed
Not Confirmed
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BENEDETTI & CO.SpA

Country
arrow
Compamed
Not Confirmed

Nimesulide

Brand Name : Nesulide

Dosage Form : Nimesulide 100Mg 30 Joined' Oral Use

Dosage Strength : 30 bust grat 100 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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10

ERREKAPPA EUROTERAPICI SpA

Country
Compamed
Not Confirmed
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ERREKAPPA EUROTERAPICI SpA

Country
arrow
Compamed
Not Confirmed

Nimesulide

Brand Name : Erreflog

Dosage Form :

Dosage Strength : Collut 200 Ml 0.1%  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Listed Dossiers

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Bal Pharma

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

Flag India
Digital Content Digital Content

Regulatory Info : Generic

Registration Country : India

Nimesulide

Brand Name : Monogesic

Dosage Form : Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

BalPharma

01

Bal Pharma

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info : Generic

Nimesulide

Dosage : Tablet

Dosage Strength : 100MG

Brand Name : Monogesic

Approval Date :

Application Number :

Registration Country : India

BalPharma

02

Bal Pharma

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

Flag India
Digital Content Digital Content

Regulatory Info : Generic

Registration Country : India

Nimesulide

Brand Name : Monogesic

Dosage Form : Gel

Dosage Strength : 10MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

BalPharma

02

Bal Pharma

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info : Generic

Nimesulide

Dosage : Gel

Dosage Strength : 10MG

Brand Name : Monogesic

Approval Date :

Application Number :

Registration Country : India

BalPharma

03

Compamed
Not Confirmed
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Nimesulide

Brand Name : Nimgen

Dosage Form : Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

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03

Compamed
Not Confirmed
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Nimesulide

Dosage : Tablet

Dosage Strength : 100MG

Brand Name : Nimgen

Approval Date :

Application Number :

Registration Country : India

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04

Compamed
Not Confirmed
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Nimesulide

Brand Name : NIMID

Dosage Form : GRANULES

Dosage Strength : 100MG/2G

Packaging : Glassine paper sachet

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

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04

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Not Confirmed
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Nimesulide

Dosage : GRANULES

Dosage Strength : 100MG/2G

Brand Name : NIMID

Approval Date :

Application Number :

Registration Country : India

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05

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Nimesulide; Acetaminophen/Paracetamol

Brand Name :

Dosage Form : Tablet

Dosage Strength : 100MG; 325MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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05

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Nimesulide; Acetaminophen/Paracetamol

Dosage : Tablet

Dosage Strength : 100MG; 325MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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06

Compamed
Not Confirmed
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Nimesulide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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06

Compamed
Not Confirmed
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Nimesulide

Dosage : Tablet

Dosage Strength : 100MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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07

Compamed
Not Confirmed
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Nimesulide

Brand Name : NIMTOP-MD

Dosage Form : Mouth Dissolving Table...

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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07

Compamed
Not Confirmed
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Not Confirmed

Nimesulide

Dosage : Mouth Dissolving Table...

Dosage Strength : 100MG

Brand Name : NIMTOP-MD

Approval Date :

Application Number :

Registration Country : India

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08

Compamed
Not Confirmed
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Compamed
Not Confirmed

Nimesulide

Brand Name :

Dosage Form : Sachet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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08

Compamed
Not Confirmed
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Compamed
Not Confirmed

Nimesulide

Dosage : Sachet

Dosage Strength : 100MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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09

Compamed
Not Confirmed
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Compamed
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Nimesulide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

09

Compamed
Not Confirmed
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Compamed
Not Confirmed

Nimesulide

Dosage : Tablet

Dosage Strength : 100MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

10

Compamed
Not Confirmed
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Compamed
Not Confirmed

Nimesulide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 100mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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10

Compamed
Not Confirmed
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Compamed
Not Confirmed

Nimesulide

Dosage : Tablet

Dosage Strength : 100mg

Brand Name :

Approval Date :

Application Number :

Registration Country : India

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Helsinn and Angelini Pharma renew distribution deal
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28 May 2024

// PHARMACEUTICAL TECHNOLOGY

https://www.pharmaceutical-technology.com/news/helsinn-angelini-distribution-deal/

PHARMACEUTICAL TECHNOLOGY
28 May 2024

https://www.pharmacompass.com/pdf/news/brainfarmas-batch-of-nimesulide-is-forbidden-by-anvisa-1502939899.pdf

ANVISA
14 Aug 2017

http://www.reuters.com/article/us-health-nsaids-heart-failure-idUSKCN12K2J1

REUTERS
21 Oct 2016

http://twofourinsight.com/experts-review-banned-drugs-consider-marketing-restrictions-india-mhfw/

TWO FOUR INSIGHT
26 Apr 2016

http://www.pharma-excipients.ch/2016/03/27/impact-of-degree-of-substitution-of-acetylated-ofada-rice-starchpolymer-on-the-release-properties-of-nimesulide-microspheres/

PHARMA-EXCIPIENTS
27 Mar 2016

http://economictimes.indiatimes.com/industry/healthcare/biotech/healthcare/40-doctors-disagree-with-governments-recent-drug-ban-list-survey/articleshow/51459620.cms

ECONOMIC TIMES
18 Mar 2016

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