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Chemistry

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Also known as: 6506-37-2, Naxogin, Nitrimidazine, Nimorazol, Nulogyl, Esclama
Molecular Formula
C9H14N4O3
Molecular Weight
226.23  g/mol
InChI Key
MDJFHRLTPRPZLY-UHFFFAOYSA-N
FDA UNII
469ULX0H4G

Nimorazole
An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
1 2D Structure

Nimorazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine
2.1.2 InChI
InChI=1S/C9H14N4O3/c14-13(15)9-7-10-8-12(9)2-1-11-3-5-16-6-4-11/h7-8H,1-6H2
2.1.3 InChI Key
MDJFHRLTPRPZLY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1COCCN1CCN2C=NC=C2[N+](=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
469ULX0H4G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Esclama

2. K 1900

3. K-1900

4. K1900

5. Naxogin

6. Nitrimidazine

7. Nulogyl

2.3.2 Depositor-Supplied Synonyms

1. 6506-37-2

2. Naxogin

3. Nitrimidazine

4. Nimorazol

5. Nulogyl

6. Esclama

7. Naxofem

8. 4-(2-(5-nitro-1h-imidazol-1-yl)ethyl)morpholine

9. Acterol

10. Acterol Forte

11. 4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine

12. Nimorazolo

13. Sirledi

14. K-1900

15. N-2-morpholinoethyl-5-nitroimidazole

16. 1-(2-n-morpholinylethyl)-5-nitroimidazole

17. Morpholine, 4-[2-(5-nitro-1h-imidazol-1-yl)ethyl]-

18. Nsc 107524

19. 4-(2-(5-nitroimidazol-1-yl)ethyl)morpholine

20. Nsc-107524

21. 4-[2-(5-nitro-1h-imidazol-1-yl)ethyl]morpholine

22. Morpholine, 4-(2-(5-nitro-1h-imidazol-1-yl)ethyl)-

23. Mls002703984

24. 469ulx0h4g

25. Morpholine, 4-(2-(5-nitroimidazol-1-yl)ethyl)-

26. Nimorazole (inn)

27. Nimorazolum

28. Nimorazole [inn]

29. 1-(.beta.-morpholinoethyl)-5-nitroimidazole

30. Morpholine, 4-[2-(5-nitroimidazol-1-yl)ethyl]-

31. Nimorazolo [dcit]

32. Nimorazol [inn-spanish]

33. Nimorazolum [inn-latin]

34. K 1900

35. 1-(beta-morpholinoethyl)-5-nitroimidazole

36. 1-(n-p-ethylmorpholine)-5-nitroimidazole

37. Nimorazole [inn:ban]

38. Einecs 229-394-4

39. 4-(2-(5-nitroimidazol-1-yl)ethyl)-morpholine

40. Brn 0533758

41. Unii-469ulx0h4g

42. Naxogin (tn)

43. Nimorazole [mi]

44. Nimorazole [mart.]

45. Dsstox_cid_31584

46. Dsstox_rid_97468

47. Nimorazole [who-dd]

48. Dsstox_gsid_57795

49. Schembl21836

50. Chembl435966

51. Dtxsid1057795

52. Chebi:134929

53. Bcp11055

54. Tox21_113897

55. Mfcd00866796

56. Nsc107524

57. S6411

58. Zinc26167988

59. Akos022174968

60. Db12172

61. Ncgc00261977-01

62. Ac-35227

63. Am807557

64. As-31120

65. Da-21636

66. Hy-16349

67. Smr001570693

68. Cas-6506-37-2

69. Wln: T6n Dotj A2- At5n Cnj Enw

70. Ft-0710009

71. A13091

72. D07352

73. 506n372

74. A834961

75. Q7037737

76. 4-[2-(5-nitro-1h-imidazol-1-yl)ethyl]morpholine #

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 226.23 g/mol
Molecular Formula C9H14N4O3
XLogP3-0.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass226.10659032 g/mol
Monoisotopic Mass226.10659032 g/mol
Topological Polar Surface Area76.1 Ų
Heavy Atom Count16
Formal Charge0
Complexity239
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antitrichomonal Agents

Agents used to treat trichomonas infections. (See all compounds classified as Antitrichomonal Agents.)


4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P01 - Antiprotozoals

P01A - Agents against amoebiasis and other protozoal diseases

P01AB - Nitroimidazole derivatives

P01AB06 - Nimorazole


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