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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

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API

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FDF

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

DIGITAL CONTENT

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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Weekly News Recap #Phispers

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Finished Drug Prices

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: 6506-37-2, Naxogin, Nitrimidazine, Nimorazol, Nulogyl, Esclama
Molecular Formula
C9H14N4O3
Molecular Weight
226.23  g/mol
InChI Key
MDJFHRLTPRPZLY-UHFFFAOYSA-N
FDA UNII
469ULX0H4G

Nimorazole
An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
1 2D Structure

Nimorazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine
2.1.2 InChI
InChI=1S/C9H14N4O3/c14-13(15)9-7-10-8-12(9)2-1-11-3-5-16-6-4-11/h7-8H,1-6H2
2.1.3 InChI Key
MDJFHRLTPRPZLY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1COCCN1CCN2C=NC=C2[N+](=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
469ULX0H4G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Esclama

2. K 1900

3. K-1900

4. K1900

5. Naxogin

6. Nitrimidazine

7. Nulogyl

2.3.2 Depositor-Supplied Synonyms

1. 6506-37-2

2. Naxogin

3. Nitrimidazine

4. Nimorazol

5. Nulogyl

6. Esclama

7. Naxofem

8. 4-(2-(5-nitro-1h-imidazol-1-yl)ethyl)morpholine

9. Acterol

10. Acterol Forte

11. 4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine

12. Nimorazolo

13. Sirledi

14. K-1900

15. N-2-morpholinoethyl-5-nitroimidazole

16. 1-(2-n-morpholinylethyl)-5-nitroimidazole

17. Morpholine, 4-[2-(5-nitro-1h-imidazol-1-yl)ethyl]-

18. Nsc 107524

19. 4-(2-(5-nitroimidazol-1-yl)ethyl)morpholine

20. Nsc-107524

21. 4-[2-(5-nitro-1h-imidazol-1-yl)ethyl]morpholine

22. Morpholine, 4-(2-(5-nitro-1h-imidazol-1-yl)ethyl)-

23. Mls002703984

24. 469ulx0h4g

25. Morpholine, 4-(2-(5-nitroimidazol-1-yl)ethyl)-

26. Nimorazole (inn)

27. Nimorazolum

28. Nimorazole [inn]

29. 1-(.beta.-morpholinoethyl)-5-nitroimidazole

30. Morpholine, 4-[2-(5-nitroimidazol-1-yl)ethyl]-

31. Nimorazolo [dcit]

32. Nimorazol [inn-spanish]

33. Nimorazolum [inn-latin]

34. K 1900

35. 1-(beta-morpholinoethyl)-5-nitroimidazole

36. 1-(n-p-ethylmorpholine)-5-nitroimidazole

37. Nimorazole [inn:ban]

38. Einecs 229-394-4

39. 4-(2-(5-nitroimidazol-1-yl)ethyl)-morpholine

40. Brn 0533758

41. Unii-469ulx0h4g

42. Naxogin (tn)

43. Nimorazole [mi]

44. Nimorazole [mart.]

45. Dsstox_cid_31584

46. Dsstox_rid_97468

47. Nimorazole [who-dd]

48. Dsstox_gsid_57795

49. Schembl21836

50. Chembl435966

51. Dtxsid1057795

52. Chebi:134929

53. Bcp11055

54. Tox21_113897

55. Mfcd00866796

56. Nsc107524

57. S6411

58. Zinc26167988

59. Akos022174968

60. Db12172

61. Ncgc00261977-01

62. Ac-35227

63. Am807557

64. As-31120

65. Da-21636

66. Hy-16349

67. Smr001570693

68. Cas-6506-37-2

69. Wln: T6n Dotj A2- At5n Cnj Enw

70. Ft-0710009

71. A13091

72. D07352

73. 506n372

74. A834961

75. Q7037737

76. 4-[2-(5-nitro-1h-imidazol-1-yl)ethyl]morpholine #

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 226.23 g/mol
Molecular Formula C9H14N4O3
XLogP3-0.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass226.10659032 g/mol
Monoisotopic Mass226.10659032 g/mol
Topological Polar Surface Area76.1 Ų
Heavy Atom Count16
Formal Charge0
Complexity239
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antitrichomonal Agents

Agents used to treat trichomonas infections. (See all compounds classified as Antitrichomonal Agents.)


4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P01 - Antiprotozoals

P01A - Agents against amoebiasis and other protozoal diseases

P01AB - Nitroimidazole derivatives

P01AB06 - Nimorazole


ABOUT THIS PAGE

Nimorazole Manufacturers

A Nimorazole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nimorazole, including repackagers and relabelers. The FDA regulates Nimorazole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nimorazole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Nimorazole manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Nimorazole Suppliers

A Nimorazole supplier is an individual or a company that provides Nimorazole active pharmaceutical ingredient (API) or Nimorazole finished formulations upon request. The Nimorazole suppliers may include Nimorazole API manufacturers, exporters, distributors and traders.

click here to find a list of Nimorazole suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Nimorazole USDMF

A Nimorazole DMF (Drug Master File) is a document detailing the whole manufacturing process of Nimorazole active pharmaceutical ingredient (API) in detail. Different forms of Nimorazole DMFs exist exist since differing nations have different regulations, such as Nimorazole USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Nimorazole DMF submitted to regulatory agencies in the US is known as a USDMF. Nimorazole USDMF includes data on Nimorazole's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Nimorazole USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Nimorazole suppliers with USDMF on PharmaCompass.

Nimorazole WC

A Nimorazole written confirmation (Nimorazole WC) is an official document issued by a regulatory agency to a Nimorazole manufacturer, verifying that the manufacturing facility of a Nimorazole active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Nimorazole APIs or Nimorazole finished pharmaceutical products to another nation, regulatory agencies frequently require a Nimorazole WC (written confirmation) as part of the regulatory process.

click here to find a list of Nimorazole suppliers with Written Confirmation (WC) on PharmaCompass.

Nimorazole GMP

Nimorazole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Nimorazole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nimorazole GMP manufacturer or Nimorazole GMP API supplier for your needs.

Nimorazole CoA

A Nimorazole CoA (Certificate of Analysis) is a formal document that attests to Nimorazole's compliance with Nimorazole specifications and serves as a tool for batch-level quality control.

Nimorazole CoA mostly includes findings from lab analyses of a specific batch. For each Nimorazole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Nimorazole may be tested according to a variety of international standards, such as European Pharmacopoeia (Nimorazole EP), Nimorazole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nimorazole USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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