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Looking for Granulation? Find Granulation Agents used in Nisoldipine to address drug delivery challenges on PharmaCompass.

Excipients
Granulation
Nisoldipine

Capsule
Emulsion
Gel
Granule / Pellet
Orodispersible Tablet
Softgels
Solution
Tablet
Topical Film
Transdermal patches

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

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AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

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EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

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ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

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Nisoldipine

ACCESS ALL DATA, CHEMISTRY

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

11 API Suppliers, 8 USDMF, 2 JDMF, 1 EU WC, 2 NDC API, 4 Listed Suppliers, $ API Reference Price

11 API Suppliers
8 USDMF
2 JDMF
1 EU WC
2 NDC API
4 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 16 FDA Orange Book, 1 Europe, 2 Listed Dossiers

19 FDF Dossiers
16 FDA Orange Book
1 Europe
2 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET, EXTENDED RELEASE;ORAL - 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 17MG, TABLET, EXTENDED RELEASE;ORAL - 20MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 25.5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 30MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 34MG, TABLET, EXTENDED RELEASE;ORAL - 40MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET, EXTENDED RELEASE;ORAL - 8.5MG

TABLET, EXTENDED RELEASE;ORAL - 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 17MG
TABLET, EXTENDED RELEASE;ORAL - 20MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 25.5MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 30MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 34MG
TABLET, EXTENDED RELEASE;ORAL - 40MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET, EXTENDED RELEASE;ORAL - 8.5MG

RELATED EXCIPIENT COMPANIES

2 Evonik, 2 Seqens, 3 DKSH, 1 Boai NKY Pharmaceuticals Ltd, 5 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 ACG Worldwide, 3 Actylis, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 23 BASF, 11 Corel Pharma Chem, 2 DFE Pharma, 1 Finar, 5 Gangwal Chemicals, 8 Ideal Cures Pvt Ltd, 28 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 9 Microlex e.U, 2 Nomisma Healthcare, 2 Novo Excipients, 1 Pharmatrans-Sanaq, 4 Pluviaendo, 1 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 3 Roquette, 6 Seppic, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 3 Sigachi Industries, 2 The Dow Chemical Company, 1 Ulanqab Kema New Material, 1 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

50 Coating Systems & Additives, 38 Fillers, Diluents & Binders, 29 Controlled & Modified Release, 16 Direct Compression, 15 Granulation, 13 Solubilizers, 12 Lubricants & Glidants, 9 Film Formers & Plasticizers, 9 Co-Processed Excipients, 8 Topical, 8 Thickeners and Stabilizers, 5 Parenteral, 5 Empty Capsules, 4 API Stability Enhancers, 4 Taste Masking, 4 Coloring Agents, 4 Emulsifying Agents, 4 Vegetarian Capsules, 3 Disintegrants & Superdisintegrants, 1 Surfactant & Foaming Agents, 1 Rheology Modifiers, 1 Chewable & Orodispersible Aids

50 Coating Systems & Additives
38 Fillers, Diluents & Binders
29 Controlled & Modified Release
16 Direct Compression
15 Granulation
13 Solubilizers
12 Lubricants & Glidants
9 Film Formers & Plasticizers
9 Co-Processed Excipients
8 Topical
8 Thickeners and Stabilizers
5 Parenteral
5 Empty Capsules
4 API Stability Enhancers
4 Taste Masking
4 Coloring Agents
4 Emulsifying Agents
4 Vegetarian Capsules
3 Disintegrants & Superdisintegrants
1 Surfactant & Foaming Agents
1 Rheology Modifiers
1 Chewable & Orodispersible Aids

DIGITAL CONTENT

1 NEWS #PharmaBuzz

1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 1 Finished Drug Prices

2 US Medicaid Prescriptions
1 Finished Drug Prices

REF. STANDARDS & IMPURITIES

5 Others

5 Others

$ API Ref.Price (USD/KG) : 2,758 Xls

Filters

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Nisoldipine

Filters

FILTER :

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32 All

01 23BASF

02 2DFE Pharma

03 1Kima Chemical

04 2Microlex e.U

05 1Pluviaendo

06 1Sigachi Industries

07 2The Dow Chemical Company

filter Capability Reset all filters

32 All

01 6Capsule

02 4Granule / Pellet

03 1Softgel Capsule

04 1Solution

05 1Suspension

06 15Tablet

07 2Topical Film

08 2Transdermal Patch

filter Country Reset all filters

32 All

01 2Austria

02 1China

03 25Germany

04 1India

05 1Turkey

06 2U.S.A

01

Pluviaendo

SODIUM DODECYL SULFATE

PackExpo

Not Confirmed

Pluviaendo

Turkey

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Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Sodium Dodecyl Sulfate

Application : Granulation, Lubricants & Glidants, Surfactant & Foaming Agents

Excipient Details : Sodium Dodecyl Sulfate is used as an ionic surfactant, lubricant, and granulating agent in the solid dosage forms such as tablets.

Pharmacopoeia Ref : N/A

Technical Specs : N/A

Ingredient(s) : Sodium Dodecyl Sulfate Excipient

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Sodium Dodecyl Sulfate Excipient

Dosage Form : Tablet

Category : Granulation, Lubricants & Glidants, Surfactant & Foaming Agents

Brand : SODIUM DODECYL SULFATE

Applications : Sodium Dodecyl Sulfate is used as an ionic surfactant, lubricant, and granulating agent in the solid dosage forms such as tablets.

Pharmacopoeia Ref : N/A

Technical Specs : N/A

Grade : Oral

Excipients Web Link

Digital Content

02

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

Grade :

Brand Name : Kollidon SR

Application : Controlled & Modified Release, Direct Compression, Granulation

Excipient Details : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 %...

Technical Specs :

Ingredient(s) : Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

Grade :

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Ingredient(s) : Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

Category : Controlled & Modified Release, Direct Compression, Granulation

Brand : KOLLIDON SR

Applications : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 % Polyvinyl acetate and 19 % povidone, 0.8 % lauryl sulfate & 0.2 % silica (4:1)

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

03

DFE Pharma

PHARMATOSE 200M

PackExpo

Not Confirmed

DFE Pharma

Germany

PackExpo

Not Confirmed

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Dosage Form : Capsule, Tablet

Grade : Oral

Brand Name : Pharmatose 200M

Application : Fillers, Diluents & Binders, Granulation

Excipient Details : Pharmatose® 200M is a pharmaceutical excipient that is a highly consistent monohydrate lactose which delivers good compaction properties. This lactose type is typically used in oral dosage forms like tablets and pharmaceutical capsules.

Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

Technical Specs : Density- Tapped density- 857 g/l, Bulk density- 589 g/l; Particle size- D10- 5 ?m, D50- 40 ?m, D90- 120 ?m; Hausner ratio- 1,46

Ingredient(s) : Lactose Monohydrate

Dosage Form : Capsule, Tablet

Grade : Oral

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Ingredient(s) : Lactose Monohydrate

Dosage Form : Capsule, Tablet

Category : Fillers, Diluents & Binders, Granulation

Brand : PHARMATOSE 200M

Applications : Pharmatose® 200M is a pharmaceutical excipient that is a highly consistent monohydrate lactose which delivers good compaction properties. This lactose type is typically used in oral dosage forms like tablets and pharmaceutical capsules.

Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP lactose monohydrate monograph

Technical Specs : Density- Tapped density- 857 g/l, Bulk density- 589 g/l; Particle size- D10- 5 ?m, D50- 40 ?m, D90- 120 ?m; Hausner ratio- 1,46

Grade : Oral

Excipients Web Link

Digital Content

04

The Dow Chemical Company

PackExpo

Not Confirmed

The Dow Chemical Company

U.S.A

PackExpo

Not Confirmed

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Dosage Form : Tablet, Capsule

Grade :

Brand Name : METHOCEL™

Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Hydroxypropyl Methylcellulose

Dosage Form : Tablet, Capsule

Grade :

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Ingredient(s) : Hydroxypropyl Methylcellulose

Dosage Form : Tablet, Capsule

Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

Brand : METHOCEL™

Applications : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

05

Kima Chemical

HYDROXYPROPYL METHYL CELLULOSE (60E3)

PackExpo

Not Confirmed

Kima Chemical

China

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Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Hydroxypropyl Methyl Cellul...

Application : Coating Systems & Additives, Fillers, Diluents & Binders, Granulation

Excipient Details : Hydroxypropyl Methyl Cellulose (60E3) is used as a binding, coating, and granulating agent for the production of tablets.

Pharmacopoeia Ref : NA

Technical Specs : NA

Ingredient(s) : Hydroxypropyl Methyl Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Hydroxypropyl Methyl Cellulose

Dosage Form : Tablet

Category : Coating Systems & Additives, Fillers, Diluents & Binders, Granulation

Brand : HYDROXYPROPYL METHYL CELLULOSE (60E3)

Applications : Hydroxypropyl Methyl Cellulose (60E3) is used as a binding, coating, and granulating agent for the production of tablets.

Pharmacopoeia Ref : NA

Technical Specs : NA

Grade : Oral

Excipients Web Link

Digital Content

06

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Tablet

Grade :

Brand Name : Kolliphor SLS

Application : Granulation

Excipient Details : Wetting agent, reduces disintegration time, Ionic solubilizer, high HLB anionic emulsifier for semi-solids and foams.

Pharmacopoeia Ref : Ph. Eur.: Sodium Laurilsulfate...

Technical Specs :

Ingredient(s) : Sodium Lauryl Sulfate

Dosage Form : Tablet

Grade :

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Ingredient(s) : Sodium Lauryl Sulfate

Dosage Form : Tablet

Category : Granulation

Brand : KOLLIPHOR SLS

Applications : Wetting agent, reduces disintegration time, Ionic solubilizer, high HLB anionic emulsifier for semi-solids and foams.

Pharmacopoeia Ref : Ph. Eur.: Sodium Laurilsulfate; USP-NF, JP: Sodium Lauryl Sulfate

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

07

BASF

KOLLIPHOR SLS FINE

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Capsule, Tablet

Grade :

Brand Name : Kolliphor SLS Fine

Application : Direct Compression, Granulation, Lubricants & Glidants

Excipient Details : Wetting agent, reducing disintegration time, direct compression, Hydrophilic lubricant, effervescent tablets.

Pharmacopoeia Ref : Ph. Eur.: Sodium Laurilsulfate...

Technical Specs :

Ingredient(s) : Sodium Lauryl Sulfate

Dosage Form : Capsule, Tablet

Grade :

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Ingredient(s) : Sodium Lauryl Sulfate

Dosage Form : Capsule, Tablet

Category : Direct Compression, Granulation, Lubricants & Glidants

Brand : KOLLIPHOR SLS FINE

Applications : Wetting agent, reducing disintegration time, direct compression, Hydrophilic lubricant, effervescent tablets.

Pharmacopoeia Ref : Ph. Eur.: Sodium Laurilsulfate; USP-NF, JP: Sodium Lauryl Sulfate

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

08

Sigachi Industries

PackExpo

Not Confirmed

Sigachi Industries

India

PackExpo

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : HiCellac

Application : Direct Compression, Granulation

Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

Dosage Form : Tablet

Category : Direct Compression, Granulation

Brand : HICELLAC

Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

Digital Content

09

Microlex e.U

MICROLEX® LCM 80.M

PackExpo

Not Confirmed

Microlex e.U

Austria

PackExpo

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Microlex® LCM 80.m

Application : Direct Compression, Granulation

Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

Ingredient(s) : Lactose Monohydrate

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Lactose Monohydrate

Dosage Form : Tablet

Category : Direct Compression, Granulation

Brand : MICROLEX® LCM 80.M

Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

Grade : Oral

Excipients Web Link

Digital Content

10

Microlex e.U

MICROLEX® LCM 120.S

PackExpo

Not Confirmed

Microlex e.U

Austria

PackExpo

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Microlex® LCM 120.s

Application : Direct Compression, Granulation

Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

Ingredient(s) : Lactose Monohydrate

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Lactose Monohydrate

Dosage Form : Tablet

Category : Direct Compression, Granulation

Brand : MICROLEX® LCM 120.S

Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

Grade : Oral

Excipients Web Link

Digital Content

11

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Granule / Pellet, Tablet

Grade :

Brand Name : Ludipress

Application : Direct Compression, Granulation

Excipient Details : Ready-to-use direct compression solution for tablets.

Pharmacopoeia Ref : Ph.Eur., USP/NF and JP

Technical Specs :

Ingredient(s) : Crospovidone, Lactose, Povidone

Dosage Form : Granule / Pellet, Tablet

Grade :

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Ingredient(s) : Crospovidone, Lactose, Povidone

Dosage Form : Granule / Pellet, Tablet

Category : Direct Compression, Granulation

Brand : LUDIPRESS

Applications : Ready-to-use direct compression solution for tablets.

Pharmacopoeia Ref : Ph.Eur., USP/NF and JP

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

12

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Granule / Pellet, Tablet

Grade :

Brand Name : Ludipress LCE

Application : Direct Compression, Granulation

Excipient Details : Ready-to-use direct compression solution for lozenges, chewables and effervescent tablets.

Pharmacopoeia Ref : Ph. Eur., USP/NF and J.P

Technical Specs :

Ingredient(s) : Lactose, Povidone

Dosage Form : Granule / Pellet, Tablet

Grade :

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Ingredient(s) : Lactose, Povidone

Dosage Form : Granule / Pellet, Tablet

Category : Direct Compression, Granulation

Brand : LUDIPRESS LCE

Applications : Ready-to-use direct compression solution for lozenges, chewables and effervescent tablets.

Pharmacopoeia Ref : Ph. Eur., USP/NF and J.P

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

13

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Capsule, Granule / Pellet, Tablet

Grade :

Brand Name : Kollidon 30 LP

Application : Fillers, Diluents & Binders, Granulation

Excipient Details : Binder for peroxide sensitive drugs in solid oral dosage forms. Drug solubilizer with low peroxide in transdermal patches.

Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

Technical Specs :

Ingredient(s) : Povidone

Dosage Form : Capsule, Granule / Pellet, Tablet

Grade :

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Ingredient(s) : Povidone

Dosage Form : Capsule, Granule / Pellet, Tablet

Category : Fillers, Diluents & Binders, Granulation

Brand : KOLLIDON 30 LP

Applications : Binder for peroxide sensitive drugs in solid oral dosage forms. Drug solubilizer with low peroxide in transdermal patches.

Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

14

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

Grade :

Brand Name : Kollidon 90 F

Application : Fillers, Diluents & Binders, Granulation, Solubilizers

Excipient Details : Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

Technical Specs :

Ingredient(s) : Povidone

Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

Grade :

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Ingredient(s) : Povidone

Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

Category : Fillers, Diluents & Binders, Granulation, Solubilizers

Brand : KOLLIDON 90 F

Applications : Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

15

BASF

PackExpo

Not Confirmed

BASF

Germany

PackExpo

Not Confirmed

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Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

Grade :

Brand Name : Soluplus

Application : Controlled & Modified Release, Granulation, Solubilizers

Excipient Details : Solubility and bioavailability enhancement, ideal for hot melt extrusion (HME)

Pharmacopoeia Ref : Polyvinyl caprolactam – poly...

Technical Specs :

Ingredient(s) : polyethylene glycol, Polyvinyl Acetate

Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

Grade :

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Ingredient(s) : polyethylene glycol, Polyvinyl Acetate

Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

Category : Controlled & Modified Release, Granulation, Solubilizers

Brand : SOLUPLUS

Applications : Solubility and bioavailability enhancement, ideal for hot melt extrusion (HME)

Pharmacopoeia Ref : Polyvinyl caprolactam – polyvinyl acetate – polyethylene glycol graft copolymer

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

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