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1. 75-52-5
2. Methane, Nitro-
3. Nitrocarbol
4. Nitrometan
5. Ch3no2
6. Nitro Methane
7. Nitro-methane
8. Nsc 428
9. Meno2
10. Ru5wg8c3f4
11. Chebi:77701
12. Nsc-428
13. Nitrometan [polish]
14. Nitromethane, Acs Reagent, >=95%
15. Ccris 1205
16. Hsdb 106
17. Einecs 200-876-6
18. Un1261
19. Unii-ru5wg8c3f4
20. Nitrometane
21. Ai3-00111
22. Nitro- Methane
23. Aci-nitromethanium
24. Nitromethane, Acs
25. Mfcd00007400
26. Nitro Fuel (salt/mix)
27. Nitromethane, 99.0%
28. Dsstox_cid_977
29. Nitromethane [mi]
30. Nitromethane, Hplc Grade
31. Nitromethane [un1261] [flammable Liquid]
32. Ch2no2
33. No2ch3
34. Ec 200-876-6
35. Nitromethane [hsdb]
36. Nitromethane [iarc]
37. Nitromethane [inci]
38. Wln: Wn1
39. Dsstox_rid_75900
40. N-hydroxy-n-oxomethanaminium
41. Dsstox_gsid_20977
42. Nitromethane [usp-rs]
43. Chembl276924
44. Nsc428
45. Dtxsid2020977
46. Nitromethane, Analytical Standard
47. Nitromethane, Reagent Grade, 96%
48. Nitromethane, For Hplc, >=96%
49. Zinc8830544
50. Tox21_200822
51. Br1297
52. Methylene, Nitro-(8ci,9ci)
53. Stl185630
54. Akos009031372
55. Un 1261
56. Cas-75-52-5
57. Methane, Nitro-,ion(1-) (8ci,9ci)
58. Ncgc00091494-01
59. Ncgc00091494-02
60. Ncgc00258376-01
61. Nitromethane, Reagentplus(r), >=99.0%
62. Nitromethane, Saj First Grade, >=90.0%
63. Ft-0659976
64. N0019
65. N0209
66. N0239
67. C19275
68. A838443
69. Q407733
70. F1908-0092
71. Nitromethane, Puriss., Absolute, Over Molecular Sieve (h2o <=0.01%), >=98.5% (gc)
| Molecular Weight | 61.040 g/mol |
|---|---|
| Molecular Formula | CH3NO2 |
| XLogP3 | 0.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 61.016378338 g/mol |
| Monoisotopic Mass | 61.016378338 g/mol |
| Topological Polar Surface Area | 45.8 Ų |
| Heavy Atom Count | 4 |
| Formal Charge | 0 |
| Complexity | 27.5 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Nitroparaffins are absorbed through lung and from GI tract. Applications to skin give no evidence of sufficient absorption to result in systemic injury. /nitroparaffins/
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4151
Nitromethane is apparently metabolized by different mechanism than nitroethane and nitropropane in that negligible amt of nitrites are found in blood following iv injection of 1 mmol in rabbits.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4154
Rabbit liver homogenate yields nitrite after incubation with nitromethane.
SCOTT EW; J IND HYG TOXICOL 25: 20 (1943)
Liver microsomes from phenobarbital pretreated rats convert nitromethane to acetone and nitrate in presence of the reduced form of nicotinamide-adenine dinucleotide phosphate and oxygen. Addition of nitromethane to oxidized rat liver microsomal suspension gave rise to substrate binding difference spectrum with peak at 437 nm, interpreted as formation of cytochrome p450 no complex. Parallel to complex formation, oxidized rat liver microsomes catalyzed prodn of formaldehyde from nitromethane in the reduced form of nicotinamide-adenine dinucleotide phosphate-dependent reaction.
PMID:7362648 SAKURAI H ET AL; BIOCHEM PHARMACOL 29 (3): 341 (1980)
Formaldehyde generated from nitromethane was found only in trace amounts after incubation with microsomes from from Fischer 344 rat liver, but none was found after incubation with rat nasal microsomes. Nitromethane inhibited rabbit liver cytochrome P450 activity, apparently competing for the same ferrohaemochrome- binding sites as carbon monoxide.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 493 (2000)
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A Nitromethane manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nitromethane, including repackagers and relabelers. The FDA regulates Nitromethane manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nitromethane API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Nitromethane manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Nitromethane supplier is an individual or a company that provides Nitromethane active pharmaceutical ingredient (API) or Nitromethane finished formulations upon request. The Nitromethane suppliers may include Nitromethane API manufacturers, exporters, distributors and traders.
click here to find a list of Nitromethane suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Nitromethane Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Nitromethane GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nitromethane GMP manufacturer or Nitromethane GMP API supplier for your needs.
A Nitromethane CoA (Certificate of Analysis) is a formal document that attests to Nitromethane's compliance with Nitromethane specifications and serves as a tool for batch-level quality control.
Nitromethane CoA mostly includes findings from lab analyses of a specific batch. For each Nitromethane CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Nitromethane may be tested according to a variety of international standards, such as European Pharmacopoeia (Nitromethane EP), Nitromethane JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nitromethane USP).
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