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Chemistry

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Also known as: 83891-03-6, Desmethylfluoxetine, 56161-73-0, 3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine, 3-phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine
Molecular Formula
C16H16F3NO
Molecular Weight
295.30  g/mol
InChI Key
WIQRCHMSJFFONW-UHFFFAOYSA-N
FDA UNII
K8D70XE2F4

Norfluoxetine
1 2D Structure

Norfluoxetine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
2.1.2 InChI
InChI=1S/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2
2.1.3 InChI Key
WIQRCHMSJFFONW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
K8D70XE2F4
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Desmethylfluoxetine

2. Norfluoxetin

3. Norfluoxetine Hydrochloride

4. Norfluoxetine, (+-)-isomer

2.3.2 Depositor-Supplied Synonyms

1. 83891-03-6

2. Desmethylfluoxetine

3. 56161-73-0

4. 3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine

5. 3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine

6. 3-phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine

7. K8d70xe2f4

8. Benzenepropanamine, Gamma-(4-(trifluoromethyl)phenoxy)-

9. Benzenepropanamine, Gamma-[4-(trifluoromethyl)phenoxy]-

10. Unii-k8d70xe2f4

11. Gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine

12. Chembl1494

13. Gtpl208

14. Schembl686500

15. Dtxsid80866540

16. Chebi:180876

17. (+/-)-desmethylfluoxetine

18. Bcp20944

19. Bdbm50180661

20. Nsc675448

21. Akos015911091

22. Norfluoxetine Hcl;n-desmethylfluoxetine

23. Nsc-675448

24. Sb32578

25. Sb32682

26. Sb38941

27. Ft-0673087

28. Ft-0673088

29. Ft-0673089

30. 3-(4-trifluoromethylphenoxy)-3-phenylproplyamine

31. A840679

32. L001023

33. Q7452012

34. 3-phenyl-3-[4-(triluoromethyl)phenoxy]propan-1-amine

35. 3-phenyl-3[4'-trifluoromethyl-phenoxy]-propan-1-amine

36. 3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine #

37. Benzenepropanamine, .gamma.-[4-(trifluoromethyl)phenoxy]-

38. Benzenepropanamine, Gamma-[4-(trifluoromethyl)phenoxy]-, (+/-)-

39. Benzenepropanamine, .gamma.-(4-(trifluoromethyl)phenoxy)-, (+/-)-

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 295.30 g/mol
Molecular Formula C16H16F3NO
XLogP33.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass295.11839862 g/mol
Monoisotopic Mass295.11839862 g/mol
Topological Polar Surface Area35.2 Ų
Heavy Atom Count21
Formal Charge0
Complexity294
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

Norfluoxetine is a known human metabolite of Fluoxetine.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


ANALYTICAL

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ABOUT THIS PAGE

Norfluoxetine Manufacturers

A Norfluoxetine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Norfluoxetine, including repackagers and relabelers. The FDA regulates Norfluoxetine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Norfluoxetine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Norfluoxetine Suppliers

A Norfluoxetine supplier is an individual or a company that provides Norfluoxetine active pharmaceutical ingredient (API) or Norfluoxetine finished formulations upon request. The Norfluoxetine suppliers may include Norfluoxetine API manufacturers, exporters, distributors and traders.

Norfluoxetine GMP

Norfluoxetine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Norfluoxetine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Norfluoxetine GMP manufacturer or Norfluoxetine GMP API supplier for your needs.

Norfluoxetine CoA

A Norfluoxetine CoA (Certificate of Analysis) is a formal document that attests to Norfluoxetine's compliance with Norfluoxetine specifications and serves as a tool for batch-level quality control.

Norfluoxetine CoA mostly includes findings from lab analyses of a specific batch. For each Norfluoxetine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Norfluoxetine may be tested according to a variety of international standards, such as European Pharmacopoeia (Norfluoxetine EP), Norfluoxetine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Norfluoxetine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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