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1. 6-dimethylamino-4,4-diphenylhexan-3-one
2. Nor-methadone
3. Normethadone Hydrochloride
1. Mepidon
2. Isomethadone I
3. Phenyldimazone
4. Eucopon
5. Desmethylmethadone
6. Noramidone
7. Normedon
8. Dacartil
9. Hoechst 10582
10. Isoamidone I
11. 467-85-6
12. 6-dimethylamino-4,4-diphenyl-3-hexanone
13. Nsc 19598
14. Nsc-19598
15. Kr2l2a68xl
16. 3-hexanone, 6-(dimethylamino)-4,4-diphenyl-
17. Hoechst-10582
18. Ids-nn-007
19. Normethadone (inn)
20. J5.915c
21. Normethadone [inn]
22. Normetadone [dcit]
23. Normetadona
24. Normetadone
25. Normethadonum
26. Normetadona [inn-spanish]
27. Normethadonum [inn-latin]
28. Normethadone [inn:ban:dcf]
29. 6-(dimethylamino)-4,4-diphenylhexan-3-one
30. Einecs 207-401-1
31. Unii-kr2l2a68xl
32. Brn 2748978
33. 6-dimethylamino-4,4-diphenyl-3-hexanon
34. Normethadon
35. 1-dimethylamino-3,3-diphenyl-4-hexanone
36. Ai3-23988
37. Dea No. 9635
38. Nonmethadone
39. 3-hexanone,4-diphenyl-
40. Normethadone [mi]
41. Dsstox_cid_31537
42. Dsstox_rid_97422
43. Dsstox_gsid_57748
44. Schembl24337
45. 4-14-00-00297 (beilstein Handbook Reference)
46. Normethadone [who-dd]
47. Chembl346331
48. 467-85-6 (free Base)
49. Dtxsid6057748
50. Chebi:135242
51. Wln: 2vxr&r&2n1&1
52. Nsc19598
53. Zinc1847280
54. Tox21_113687
55. 6-dimethylamio-4-diphenyl-3-hexanone
56. Db11609
57. Ncgc00249911-01
58. Cas-467-85-6
59. D07384
60. Q1218578
61. 1,1-diphenyl-1-(2-dimethylaminoethyl)-2-butanone
| Molecular Weight | 295.4 g/mol |
|---|---|
| Molecular Formula | C20H25NO |
| XLogP3 | 3.5 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 7 |
| Exact Mass | 295.193614421 g/mol |
| Monoisotopic Mass | 295.193614421 g/mol |
| Topological Polar Surface Area | 20.3 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 320 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For use in the treatment of cough when other less potent treatments have failed.
FDA Label
Normethadone is an opioid which suppresses coughing by central and peripheral mechanisms.
Analgesics, Opioid
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)
Antitussive Agents
Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. (See all compounds classified as Antitussive Agents.)
R - Respiratory system
R05 - Cough and cold preparations
R05D - Cough suppressants, excl. combinations with expectorants
R05DA - Opium alkaloids and derivatives
R05DA06 - Normethadone
Normethadone activates central opioid receptors in the medulla to supress the cough reflex. It also likely activates peripheral opioid receptors to inhibit signalling by irritant receptors of the airway.
INTERMEDIATES SUPPLIERS
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]ABOUT THIS PAGE
A Normethadone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Normethadone, including repackagers and relabelers. The FDA regulates Normethadone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Normethadone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Normethadone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Normethadone supplier is an individual or a company that provides Normethadone active pharmaceutical ingredient (API) or Normethadone finished formulations upon request. The Normethadone suppliers may include Normethadone API manufacturers, exporters, distributors and traders.
click here to find a list of Normethadone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Normethadone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Normethadone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Normethadone GMP manufacturer or Normethadone GMP API supplier for your needs.
A Normethadone CoA (Certificate of Analysis) is a formal document that attests to Normethadone's compliance with Normethadone specifications and serves as a tool for batch-level quality control.
Normethadone CoA mostly includes findings from lab analyses of a specific batch. For each Normethadone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Normethadone may be tested according to a variety of international standards, such as European Pharmacopoeia (Normethadone EP), Normethadone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Normethadone USP).
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