Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)

Molecular Formula	C₂₁H₃₂N₃O₅P
Molecular Weight	437.5 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	8
Exact Mass	437.20795813 g/mol
Monoisotopic Mass	437.20795813 g/mol
Topological Polar Surface Area	137 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	459
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

1 of 6
Drug Name	Disopyramide phosphate
PubMed Health	Disopyramide (By mouth)
Drug Classes	Antiarrhythmic, Group IA
Drug Label	Disopyramide Phosphate is an antiarrhythmic drug available for oral administration in capsules containing 100 mg or 150 mg of disopyramide base, present as the phosphate. The base content of the phosphate salt is 77.6%. The structural formula of Diso...
Active Ingredient	Disopyramide phosphate
Dosage Form	Capsule
Route	Oral
Strength	eq 100mg base; eq 150mg base
Market Status	Prescription
Company	Watson Labs; Teva

2 of 6
Drug Name	Norpace
Active Ingredient	Disopyramide phosphate
Dosage Form	Capsule
Route	Oral
Strength	eq 100mg base; eq 150mg base
Market Status	Prescription
Company	Gd Searle

3 of 6
Drug Name	Norpace cr
PubMed Health	Disopyramide (By mouth)
Drug Classes	Antiarrhythmic, Group IA
Drug Label	Norpace (disopyramide phosphate) is an antiarrhythmic drug available for oral administration in immediate-release and controlled-release capsules containing 100 mg or 150 mg of disopyramide base, present as the phosphate. The base content of the phos...
Active Ingredient	Disopyramide phosphate
Dosage Form	Capsule, extended release
Route	Oral
Strength	eq 100mg base; eq 150mg base
Market Status	Prescription
Company	Gd Searle

4 of 6
Drug Name	Disopyramide phosphate
PubMed Health	Disopyramide (By mouth)
Drug Classes	Antiarrhythmic, Group IA
Drug Label	Disopyramide Phosphate is an antiarrhythmic drug available for oral administration in capsules containing 100 mg or 150 mg of disopyramide base, present as the phosphate. The base content of the phosphate salt is 77.6%. The structural formula of Diso...
Active Ingredient	Disopyramide phosphate
Dosage Form	Capsule
Route	Oral
Strength	eq 100mg base; eq 150mg base
Market Status	Prescription
Company	Watson Labs; Teva

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