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Chemistry

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Also known as: Obidoxime, 114-90-9, Obidoxime dichloride, Obidoxim, Obidoxime (dichloride), 3hxr312z9m
Molecular Formula
C14H16Cl2N4O3
Molecular Weight
359.2  g/mol
InChI Key
ZIFJVJZWVSPZLE-UHFFFAOYSA-N
FDA UNII
3HXR312Z9M

Obidoxime Chloride
Cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti.
1 2D Structure

Obidoxime Chloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(NE)-N-[[1-[[4-[(E)-hydroxyiminomethyl]pyridin-1-ium-1-yl]methoxymethyl]pyridin-1-ium-4-yl]methylidene]hydroxylamine;dichloride
2.1.2 InChI
InChI=1S/C14H14N4O3.2ClH/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H
2.1.3 InChI Key
ZIFJVJZWVSPZLE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=C[N+](=CC=C1C=NO)COC[N+]2=CC=C(C=C2)C=NO.[Cl-].[Cl-]
2.1.5 Isomeric SMILES
C1=C[N+](=CC=C1/C=N/O)COC[N+]2=CC=C(C=C2)/C=N/O.[Cl-].[Cl-]
2.2 Other Identifiers
2.2.1 UNII
3HXR312Z9M
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Chloride, Obidoxime

2. Obidoxim

3. Obidoxime

4. Toxogonin

2.3.2 Depositor-Supplied Synonyms

1. Obidoxime

2. 114-90-9

3. Obidoxime Dichloride

4. Obidoxim

5. Obidoxime (dichloride)

6. 3hxr312z9m

7. Toksobidin

8. Toxogonine

9. 1,1'-(oxydimethylene)bis(4-formylpyridinium) Dichloride Dioxime

10. Nsc-757237

11. Obidoxime Chloride (usan)

12. Pyridinium, 1,1'-(oxybis(methylene))bis(4-(hydroxyimino)methyl)-, Dichloride

13. Luh(sub 6)

14. Obidoxime Hydrochloride

15. Obidoxime Chloride [usan]

16. Luh6

17. Lueh 6

18. Obidoximi Chloridum

19. Obidoxime Dihydrochloride

20. Toxogonin Dichloride

21. Chlorure D'obidoxime

22. Cloruro De Obidoxima

23. Obidoxime Chloride [usan:inn]

24. Obidoximi Chloridum [inn-latin]

25. Chlorure D'obidoxime [inn-french]

26. Cloruro De Obidoxima [inn-spanish]

27. Einecs 204-059-5

28. Unii-3hxr312z9m

29. Obidoximchlorid

30. Bis(isonicotinaldoxime 1-methyl) Ether Dichloride

31. 1,3-bis(4-aldoximinopyridinium) Dimethyl Ether Bichloride

32. N,n-dimethyleneoxidebis(pyridinium-4-aldoxime) Dichloride

33. Bis(4-hydroxyiminomethylpyridinium-1-methyl)ether Dichloride

34. 1,1'-(oxybis(methylene))bis(4-((hydroxyimino)methyl)pyridin-1-ium) Chloride

35. 1,1'-(oxydimethylene)bis(4-formylpyridinium) Dioxime Dichloride

36. 1,1'-(oxydimethylene)bis(4-formylpyridinium)dichloride Dioxime

37. 1,3-bis(4-hydroxyiminomethyl-1-pyridinio)-2-oxapropane Dichloride

38. N,n-dimethylenoxid-bis-(pyridinium-4-aldoxim)-dichlorid [german]

39. Ether Bis-14-hydroxy-iminomethylopyridine-(1)-metylodichloride [polish]

40. 1,1'-(oxybis(methylene))bis(4-(hydroxyimino)methyl)pyridinium Dichloride

41. Obidoxime Chloride [mi]

42. N,n-dimethylenoxid-bis-(pyridinium-4-aldoxim)-dichlorid

43. Obidoxime Chloride [inn]

44. Obidoxime Chloride [mart.]

45. Ether Bis-14-hydroxy-iminomethylopyridine-(1)-metylodichloride

46. Obidoxime Chloride [who-dd]

47. Mfcd00038864

48. Pyridinium, 1,1'-(oxydimethylene)bis(4-formyl-, Dichloride, Dioxime

49. Akos025397238

50. Akos030241577

51. Cs-w011824

52. Hy-w011108

53. Nsc 757237

54. Obidoxime Chloride, >=95.0% (hplc)

55. D05215

56. Obidoxime Chloride, Analytical Reference Material

57. J-003154

58. 1,1'-(oxybis(methylene))bis(4-((hydroxyimino)methyl)pyridin-1-ium)chloride

59. 1,1'[oxybis(methylene)]-bis[4-(hydroxyimino)methyl]pyridinium Dichloride

60. Pyridinium, 1,1'-[oxybis(methylene)]bis[4-[(hydroxyimino)methyl]-, Chloride (1:2)

2.4 Create Date
2019-01-15
3 Chemical and Physical Properties
Molecular Weight 359.2 g/mol
Molecular Formula C14H16Cl2N4O3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass358.0599458 g/mol
Monoisotopic Mass358.0599458 g/mol
Topological Polar Surface Area82.2 Ų
Heavy Atom Count23
Formal Charge0
Complexity303
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cholinesterase Reactivators

Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates. (See all compounds classified as Cholinesterase Reactivators.)


4.2 ATC Code

V - Various

V03 - All other therapeutic products

V03A - All other therapeutic products

V03AB - Antidotes

V03AB13 - Obidoxime


API Reference Price

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28-May-2022
04-Mar-2024
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ABOUT THIS PAGE

Obidoxime Chloride Manufacturers

A Obidoxime Chloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Obidoxime Chloride, including repackagers and relabelers. The FDA regulates Obidoxime Chloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Obidoxime Chloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Obidoxime Chloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Obidoxime Chloride Suppliers

A Obidoxime Chloride supplier is an individual or a company that provides Obidoxime Chloride active pharmaceutical ingredient (API) or Obidoxime Chloride finished formulations upon request. The Obidoxime Chloride suppliers may include Obidoxime Chloride API manufacturers, exporters, distributors and traders.

click here to find a list of Obidoxime Chloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Obidoxime Chloride WC

A Obidoxime Chloride written confirmation (Obidoxime Chloride WC) is an official document issued by a regulatory agency to a Obidoxime Chloride manufacturer, verifying that the manufacturing facility of a Obidoxime Chloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Obidoxime Chloride APIs or Obidoxime Chloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Obidoxime Chloride WC (written confirmation) as part of the regulatory process.

click here to find a list of Obidoxime Chloride suppliers with Written Confirmation (WC) on PharmaCompass.

Obidoxime Chloride GMP

Obidoxime Chloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Obidoxime Chloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Obidoxime Chloride GMP manufacturer or Obidoxime Chloride GMP API supplier for your needs.

Obidoxime Chloride CoA

A Obidoxime Chloride CoA (Certificate of Analysis) is a formal document that attests to Obidoxime Chloride's compliance with Obidoxime Chloride specifications and serves as a tool for batch-level quality control.

Obidoxime Chloride CoA mostly includes findings from lab analyses of a specific batch. For each Obidoxime Chloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Obidoxime Chloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Obidoxime Chloride EP), Obidoxime Chloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Obidoxime Chloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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