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Chemistry

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Drugs in Development

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Details:

Ocrevus Zunovo (ocrelizumab-hyaluronidase) is a humanised mAb-enzyme designed to target CD20-positive B cells, approved for the treatment of multiple sclerosis.


Lead Product(s): Ocrelizumab,Hyaluronidase

Therapeutic Area: Neurology Brand Name: Ocrevus Zunovo

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 13, 2024

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01

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : Ocrevus Zunovo (ocrelizumab-hyaluronidase) is a humanised mAb-enzyme designed to target CD20-positive B cells, approved for the treatment of multiple sclerosis.

Brand Name : Ocrevus Zunovo

Molecule Type : Large molecule

Upfront Cash : Not Applicable

September 13, 2024

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Details:

OCREVUS (ocrelizumab) is a humanised monoclonal antibody designed to target CD20-positive B cells, approved as a subcutaneous injection, for the treatment of multiple sclerosis.


Lead Product(s): Ocrelizumab,Dexamethasone,Desloratadine

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 25, 2024

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02

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : OCREVUS (ocrelizumab) is a humanised monoclonal antibody designed to target CD20-positive B cells, approved as a subcutaneous injection, for the treatment of multiple sclerosis.

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

June 25, 2024

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Details:

Ocrevus (ocrelizumab) is a twice-yearly subcutaneous injection designed to target CD20-positive B cells for treating progressive and relapsing multiple sclerosis.


Lead Product(s): Ocrelizumab,Dexamethasone,Desloratadine

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: Phase IIIProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 17, 2024

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03

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : Ocrevus (ocrelizumab) is a twice-yearly subcutaneous injection designed to target CD20-positive B cells for treating progressive and relapsing multiple sclerosis.

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

April 17, 2024

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Details:

OCREVUS (ocrelizumab) is a humanised monoclonal antibody designed to target CD20-positive B cells, which is being investigated as a a 10-minute subcutaneous injection, for the treatment of multiple sclerosis.


Lead Product(s): Ocrelizumab,Dexamethasone,Desloratadine

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: Phase IIIProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 13, 2023

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04

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : OCREVUS (ocrelizumab) is a humanised monoclonal antibody designed to target CD20-positive B cells, which is being investigated as a a 10-minute subcutaneous injection, for the treatment of multiple sclerosis.

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

July 13, 2023

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Details:

OCREVUS (ocrelizumab) is a humanised monoclonal antibody designed to target CD20-positive B cells, a specific type of immune cell thought to be a key contributor to myelin (nerve cell insulation and support) and axonal (nerve cell) damage.


Lead Product(s): Ocrelizumab

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 26, 2022

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05

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : OCREVUS (ocrelizumab) is a humanised monoclonal antibody designed to target CD20-positive B cells, a specific type of immune cell thought to be a key contributor to myelin (nerve cell insulation and support) and axonal (nerve cell) damage.

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

October 26, 2022

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Details:

OCREVUS (ocrelizumab) data will show significant benefit on slowing disease activity and progression in patients with treatment-naive early-stage relapsing-remitting multiple sclerosis (RRMS).


Lead Product(s): Ocrelizumab

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 19, 2022

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06

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : OCREVUS (ocrelizumab) data will show significant benefit on slowing disease activity and progression in patients with treatment-naive early-stage relapsing-remitting multiple sclerosis (RRMS).

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

October 19, 2022

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Details:

Ocrevus (Ocrelizumab) data will show significant benefit on slowing disease activity and progression in patients with treatment-naïve early-stage relapsing-remitting multiple sclerosis (RRMS).


Lead Product(s): Ocrelizumab

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 18, 2022

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07

Genentech

U.S.A
arrow
American Pharma Summit
Not Confirmed

Genentech

U.S.A
arrow
American Pharma Summit
Not Confirmed

Details : Ocrevus (Ocrelizumab) data will show significant benefit on slowing disease activity and progression in patients with treatment-naïve early-stage relapsing-remitting multiple sclerosis (RRMS).

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

October 18, 2022

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Details:

Analysis demonstrated positive effects of OCREVUS on cognition, with 70% of patients having improved cognition, as measured with SDMT. Clinically meaningful improvement was observed in 34% of patients treated with OCREVUS and worsening in 30% of patients treated with OCREVUS.


Lead Product(s): Ocrelizumab

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 04, 2022

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08

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : Analysis demonstrated positive effects of OCREVUS on cognition, with 70% of patients having improved cognition, as measured with SDMT. Clinically meaningful improvement was observed in 34% of patients treated with OCREVUS and worsening in 30% of patients...

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

April 04, 2022

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Details:

OCREVUS (ocrelizumab), a humanised monoclonal antibody designed to target CD20-positive B cells, a specific type of immune cell thought to be a key contributor to myelin (nerve cell insulation and support) and axonal (nerve cell) damage.


Lead Product(s): Ocrelizumab

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Genentech

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 25, 2022

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09

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : OCREVUS (ocrelizumab), a humanised monoclonal antibody designed to target CD20-positive B cells, a specific type of immune cell thought to be a key contributor to myelin (nerve cell insulation and support) and axonal (nerve cell) damage.

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

March 25, 2022

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Details:

OCREVUS resulted in a 35% reduction in the risk of patients with RMS needing a walking aid over seven and a half years compared with patients who switched from interferon beta-1a to OCREVUS after the 96-week double-blind period.


Lead Product(s): Ocrelizumab

Therapeutic Area: Neurology Brand Name: Ocrevus

Study Phase: ApprovedProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 13, 2021

blank

10

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

F. Hoffmann-La Roche

Switzerland
arrow
American Pharma Summit
Not Confirmed

Details : OCREVUS resulted in a 35% reduction in the risk of patients with RMS needing a walking aid over seven and a half years compared with patients who switched from interferon beta-1a to OCREVUS after the 96-week double-blind period.

Brand Name : Ocrevus

Molecule Type : Large molecule

Upfront Cash : Not Applicable

October 13, 2021

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01

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : CNS & Anesthesia

Currency : USD

2019 Revenue in Millions : 3,819

2018 Revenue in Millions : 2,424

Growth (%) : 58

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02

Brand Name : Ocrevus Royalties

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus Royalties

U.S.A
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : CNS & Anesthesia

Currency : USD

2020 Revenue in Millions : 845

2019 Revenue in Millions : 688

Growth (%) : 23

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03

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : CNS & Anesthesia

Currency : USD

2020 Revenue in Millions : 4,820

2019 Revenue in Millions : 4,131

Growth (%) : 17

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04

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : Neurology

Currency : USD

2021 Revenue in Millions : 5,440

2020 Revenue in Millions : 4,586

Growth (%) : 17

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05

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : Neurology

Currency : USD

2022 Revenue in Millions : 6,598

2021 Revenue in Millions : 5,440

Growth (%) : 21

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06

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : Neurology

Currency : USD

2023 Revenue in Millions : 7,403

2022 Revenue in Millions : 6,598

Growth (%) : 6

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07

Brand Name : Ocrevus Royalties

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus Royalties

U.S.A
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : CNS & Anesthesia

Currency : USD

2019 Revenue in Millions : 688

2018 Revenue in Millions : 478

Growth (%) : 44

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08

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : Neurological/Mental Disorders

Currency : USD

2017 Revenue in Millions : 921

2016 Revenue in Millions : 0

Growth (%) : New Launch

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09

Brand Name : Ocrevus

Ocrelizumab

arrow
euroPLX 86 Munich
Not Confirmed

Brand Name : Ocrevus

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

Ocrelizumab

Main Therapeutic Indication : Neurological/Mental Disorders

Currency : USD

2018 Revenue in Millions : 2,377

2017 Revenue in Millions : 878

Growth (%) : 171%

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