Synopsis
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JDMF
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EU WC
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KDMF
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NDC API
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1. 2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate
2. 2-ethylhexyl 2-cyano-3,3-diphenylacrylate
1. 6197-30-4
2. 2-ethylhexyl 2-cyano-3,3-diphenylacrylate
3. Octocrilene
4. 2-propenoic Acid, 2-cyano-3,3-diphenyl-, 2-ethylhexyl Ester
5. 2-ethylhexyl 2-cyano-3,3-diphenylprop-2-enoate
6. Octocrilene [inn]
7. 2-cyano-3,3-diphenylacrylic Acid 2-ethylhexyl Ester
8. 5a68wgf6wm
9. Mls002454364
10. Octocrilene (inn)
11. Nsc-760433
12. Parsol 340
13. Uv-3039
14. Ncgc00091585-03
15. Ncgc00091585-05
16. Smr001371988
17. Dsstox_cid_5299
18. Dsstox_rid_77734
19. 2-ethylhexyl 2-cyano-3,3-diphenylacrylate, 97%
20. Dsstox_gsid_25299
21. Octocrylene [usan]
22. Octocrileno
23. Octocrilenum
24. Octocrilenum [inn-latin]
25. Octocrileno [inn-spanish]
26. Uv Absorber-3
27. Cas-6197-30-4
28. Ccris 4814
29. Einecs 228-250-8
30. Octocrylene [usan:usp]
31. Unii-5a68wgf6wm
32. Octocrilen
33. 2-ethylhexyl 2-cyano-3,3-diphenyl-2-acrylate
34. 2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate
35. Octocrylene (usp)
36. Neo Heliopan 303
37. Uvinul N539
38. 80135-31-5
39. 2-ethylhexyl 2-cyano-3,3-diphenyl-prop-2-enoate
40. Uvinul N-539
41. Octocrylene [mi]
42. 2-cyano-3,3-diphenyl-2-propenoic Acid, 2-ethylhexyl Ester
43. Octocrylene [inci]
44. Ec 228-250-8
45. Octocrilene [mart.]
46. Schembl16483
47. Octocrilene [who-dd]
48. Octocrylene [usp-rs]
49. Cid_22571
50. Octocrylene, Analytical Standard
51. Chembl1201147
52. Dtxsid9025299
53. Bdbm74416
54. Octocrylene [orange Book]
55. Chebi:135526
56. Hms3039d04
57. Octocrylene [usp Impurity]
58. Octocrylene [usp Monograph]
59. Amy40810
60. Bcp15293
61. Hy-a0087
62. Octyl 2-cyano-3,3-diphenylacrylate
63. Tox21_111153
64. Tox21_200236
65. Mfcd00059260
66. S1750
67. Akos015900539
68. Tox21_111153_1
69. Ac-7027
70. Ccg-268181
71. Cs-4296
72. Nsc 760433
73. Anthelios Sx Component Octocrylene
74. Ncgc00091585-01
75. Ncgc00091585-04
76. Ncgc00091585-06
77. Ncgc00257790-01
78. As-13821
79. Capital Soleil Component Octocrylene
80. 2-ethylhexyl 2-cyano-3,3-diphenyl-acrylate
81. 2-ethylhexyl Alpha-cyano-beta-phenylcinnamate
82. 2-ethylhexyl-alpha-cyano-beta-phenylcinnamate
83. Ft-0612234
84. Octocrylene Component Of Anthelios Sx
85. Octocrylene Component Of Capital Soleil
86. D05227
87. D70471
88. A833511
89. Q424805
90. Sr-01000864577
91. Q-201499
92. Sr-01000864577-2
93. 2-cyano-3,3-diphenyl-acrylic Acid 2-ethylhexyl Ester
94. 2-cyano-3,3-diphenylacrylic Acid-2-ethylhexyl Ester
95. 2-cyano-3,3-diphenyl-acrylic Acid 2-ethyl-hexyl Ester
96. (7-methoxy-8-(3-methyl-2-buten-1-yl)-2h-chromen-2-one)
97. Octocrylene, United States Pharmacopeia (usp) Reference Standard
98. Octocrylene, Pharmaceutical Secondary Standard; Certified Reference Material
Molecular Weight | 361.5 g/mol |
---|---|
Molecular Formula | C24H27NO2 |
XLogP3 | 7.1 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 10 |
Exact Mass | 361.204179104 g/mol |
Monoisotopic Mass | 361.204179104 g/mol |
Topological Polar Surface Area | 50.1 Ų |
Heavy Atom Count | 27 |
Formal Charge | 0 |
Complexity | 510 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
In the US, Octocrylene has been evaluated by the FDA and is considered safe for use up to 10% in the formula. Similarly, the EU allows its use up to 10% in a formula while Health Canada allows a maximum use level of 12%.
Absorption
Ecamsule is used topically, it not absorbed or metabolized.
Route of Elimination
Ecamsule is used topically, it not absorbed.
Volume of Distribution
Ecamsule is only used topically, it not absorbed.
Clearance
Ecamsule is used topically, it not absorbed or metabolized.
Ecamsule is used topically, it not absorbed.
Ecamsule is only used topically, it does not have half life
Octocrylene is an effective oil soluble liquid UVB filter. It has excellent dissolving properties for crystalline UV filters. Due to its outstanding photostability it is used as photostabilizer. Conjugated acrylate portion absorbs UVB and short-wave UVA (ultraviolet) rays with wavelengths in the range of 280-320 nm which protects the skin from direct DNA damage. The ethylhexanol portion is a fatty alcohol, which functions as an emollient due to it's hydrophobicity.
USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 12600
Submission : 1997-07-17
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 28329
Submission : 2014-05-21
Status : Inactive
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 12600
Submission : 1997-07-17
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 28329
Submission : 2014-05-21
Status : Inactive
Type : II
API Imports and Exports
Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
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26 Jan 2021
REF. STANDARDS & IMPURITIES
CAS Number : 6197-30-4
Quantity Per Vial : 500
Sale Unit : mg
Price : $245.00
Details : Material Origin- Chemical Synthesis; USMCA- N...
Monograph :
Storage :
Code/Batch No : Catalog #1477411 / I0L471
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