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Chemistry

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Also known as:
Molecular Formula
C17H20N4S
Molecular Weight
312.4  g/mol
InChI Key
WXPNDRBBWZMPQG-UHFFFAOYSA-N

Olanzapine
1 2D Structure

Olanzapine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
2.1.2 InChI
InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
2.1.3 InChI Key
WXPNDRBBWZMPQG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
2.1.5 Isomeric SMILES
CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
2.2 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 312.4 g/mol
Molecular Formula C17H20N4S
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass312.14086783 g/mol
Monoisotopic Mass312.14086783 g/mol
Topological Polar Surface Area56.2 A^2
Heavy Atom Count22
Formal Charge0
Complexity543
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 8  
Drug NameOlanzapine
PubMed HealthOlanzapine
Drug ClassesAntipsychotic
Drug LabelOlanzapine is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresponds to a...
Active IngredientOlanzapine
Dosage FormTablet; Injectable; Tablet, orally disintegrating
Routeoral; Oral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusTentative Approval; Prescription
CompanyMylan Pharms; Apotex; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Barr Labs; Sandoz; Par Pharm; Roxane; Teva Pharms; Macleods Pharms; Jubilant Generics; Luitpold; Dr Reddys Labs; Orchid Hlthcare; Mylan

2 of 8  
Drug NameSymbyax
PubMed HealthOlanzapine/Fluoxetine (By mouth)
Drug ClassesAntidepressant, Antipsychotic
Active IngredientFluoxetine hydrochloride; olanzapine
Dosage FormCapsule
RouteOral
Strengtheq 50mg base; eq 6mg base; eq 12mg base; eq 3mg base; eq 25mg base
Market StatusPrescription
CompanyLilly

3 of 8  
Drug NameZyprexa
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet; Injectable
RouteOral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

4 of 8  
Drug NameZyprexa zydis
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet, orally disintegrating
RouteOral
Strength15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

5 of 8  
Drug NameOlanzapine
PubMed HealthOlanzapine
Drug ClassesAntipsychotic
Drug LabelOlanzapine is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresponds to a...
Active IngredientOlanzapine
Dosage FormTablet; Injectable; Tablet, orally disintegrating
Routeoral; Oral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusTentative Approval; Prescription
CompanyMylan Pharms; Apotex; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Barr Labs; Sandoz; Par Pharm; Roxane; Teva Pharms; Macleods Pharms; Jubilant Generics; Luitpold; Dr Reddys Labs; Orchid Hlthcare; Mylan

6 of 8  
Drug NameSymbyax
PubMed HealthOlanzapine/Fluoxetine (By mouth)
Drug ClassesAntidepressant, Antipsychotic
Active IngredientFluoxetine hydrochloride; olanzapine
Dosage FormCapsule
RouteOral
Strengtheq 50mg base; eq 6mg base; eq 12mg base; eq 3mg base; eq 25mg base
Market StatusPrescription
CompanyLilly

7 of 8  
Drug NameZyprexa
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet; Injectable
RouteOral; Intramuscular
Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

8 of 8  
Drug NameZyprexa zydis
Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
Active IngredientOlanzapine
Dosage FormTablet, orally disintegrating
RouteOral
Strength15mg; 5mg; 10mg; 20mg
Market StatusPrescription
CompanyLilly

Listed Suppliers

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euroPLX 86 Munich
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Virtual BoothNortec Quimica is the largest API manufacturer in Latin America.

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Olanzapine

About the Company : Nortec Química stands as the largest manufacturer of Active Pharmaceutical Ingredients (IFAs) in Latin America, embarking on its mission to ensure the availability of quality medi...

Nortec Química stands as the largest manufacturer of Active Pharmaceutical Ingredients (IFAs) in Latin America, embarking on its mission to ensure the availability of quality medicines with IFAs developed in Brazil. The company's approach involves leveraging the expertise of major National Research Centers and tapping into the experience of the Brazilian Chemical and Petrochemical Industry. Nortec Química plays a significant role in the Brazilian pharmaceutical landscape and the Unified Health System (SUS), producing APIs for branded, generic, and similar medicines, as well as medicines dedicated to addressing neglected diseases.
Nortec Quimica

02

Inke S.A

Spain
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Virtual BoothInke S.A: APIs manufacturing plant.

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Olanzapine

About the Company : Inke S.A., is focused since 1980 in the development and manufacture of the highest quality Active Pharmaceutical Ingredients (APIs) with complex synthesis processes for diverse the...

Inke S.A., is focused since 1980 in the development and manufacture of the highest quality Active Pharmaceutical Ingredients (APIs) with complex synthesis processes for diverse therapeutic areas, but mainly for use in Respiratory. Inke has been successfully inspected by every major global authority for a wide array of products (last inspection on behalf of US-FDA was in 2023). For the last two decades, the company has made strong strides to become a prestige provider of respiratory APIs for inhalation.
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03

DKSH

Switzerland
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Virtual BoothDKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

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Olanzapine

About the Company : DKSH, founded with the goal of improving people's lives, assists businesses with market expansion and business growth in both existing and emerging markets. It has been fostering g...

DKSH, founded with the goal of improving people's lives, assists businesses with market expansion and business growth in both existing and emerging markets. It has been fostering growth for businesses in Asia and beyond for over 155 years. DKSH operates in 36 markets, is listed on the SIX Swiss Exchange, employs 33,100 specialists, and generated net sales of CHF 11.1 billion in 2021. It is the leading global distributor of innovative pharma ingredients for pharmaceutical synthesis and formulation. It offers a range of products, ranging from animal care products to packaging materials, intermediates to nutraceuticals, and APIs to excipients.
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04

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Virtual BoothJai Radhe Sales is your partner for all your sourcing needs.

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Olanzapine

About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.
Jai Radhe Sales

05

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Virtual BoothSynnat Pharma is one of the leading active pharmaceutical ingredients and intermediates manufacturers.

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Olanzapine

About the Company : Synnat Pharma is a fast-growing pharmaceutical company dedicated to the identification, development, production and distribution of potent phytochemicals and botanical extracts. AP...

Synnat Pharma is a fast-growing pharmaceutical company dedicated to the identification, development, production and distribution of potent phytochemicals and botanical extracts. APIs manufactured by Synnat are used by major drug formulators worldwide. Manufacturing activities are carried out as per ICH cGMP guidelines and several conventional and modern techniques are used for the isolation, semi-synthesis and purification of its products. Synnat Pharma has a presence in semi-regulated and non-regulated markets and is now entering regulated markets.
Synnat

06

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Virtual BoothHRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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Olanzapine

About the Company : HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It...

HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It offers services such as sourcing, manufacturing & supply, helping partners enter new markets worldwide. Its strong partnerships with major players in the pharma and food additive industries help HRV Global effectively promote projects and products. HRV Global represents over 30 large Indian drugmakers, primarily targeting Europe, the US & the Middle East markets. Headquartered in India, HRV Global has offices in the US, Switzerland, Dubai, Lithuania & Turkey.
HRV Global Life Sciences

07

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Virtual BoothNeuland Laboratories- A dedicated 100% API provider.

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Olanzapine

About the Company : Established in 1984, Neuland Laboratories Limited is a publicly listed company headquartered in Hyderabad, India. The company provides solutions across the entire spectrum of the p...

Established in 1984, Neuland Laboratories Limited is a publicly listed company headquartered in Hyderabad, India. The company provides solutions across the entire spectrum of the pharmaceutical industry’s chemistry requirements, from the synthesis of library compounds to supplying NCEs and advanced intermediates at various stages in the clinical life cycle, as well as commercial launch. Neuland’s expertise is in the manufacturing of APIs and advanced intermediates from its USFDA-approved facilities. Its core competency lies in the application of powerful process chemistry to manufacturing in a regulatory-compliant environment.
Neuland

08

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Virtual BoothOctavius has been empowering lives since 1980 by providing quality products like DC granules, APIs and FDFs.

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Olanzapine

About the Company : Octavius Pharma is a global leader in Directly Compressible Granules with over 40 years of experience in Formulation development, manufacturing and commercialization. It offers a w...

Octavius Pharma is a global leader in Directly Compressible Granules with over 40 years of experience in Formulation development, manufacturing and commercialization. It offers a wide range of products such as tablets, capsules, syrups and ointments. Its portfolio includes finished dosage formulations, herbal/food supplements and APIs. It exports bulk drugs, finished formulations and APIs, while maintaining quality in compliance with WHO GMP norms. With an experienced team, Octavius Pharma provides consulting services for formulation development and marketing. Octavius exports to LATAM, Middle East, African, Asian and CIS countries.
Octavius Pharma

09

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Virtual BoothAtman Pharmaceuticals: A One Stop Solution Provider to All Your API Needs.

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Olanzapine

About the Company : Atman Pharmaceuticals is a fully integrated pharmaceutical company that has distinguished itself as a leader in Bulk Drugs (API) marketing both domestically in India and overseas. ...

Atman Pharmaceuticals is a fully integrated pharmaceutical company that has distinguished itself as a leader in Bulk Drugs (API) marketing both domestically in India and overseas. With a heritage spanning over 33 years and vast experience, we have earned a reputation for delivering high-quality and abundant services within the industry. Our emergence as prominent solution providers in the pharmaceutical business underscores our commitment to excellence.
Atman Pharmaceuticals

10

euroPLX 86 Munich
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Olanzapine

About the Company : Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets f...

Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets for the generics market across the world. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today.Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Smilax manufactures APIs and API Intermediates at its state-of-the-art manufacturing facilities located at Hyderabad, Telangana and Visakhapatnam, Andhra Pradesh, India. Supported by a highly qualified and competent technical team, and endowed with strengths in research and development, Smilax continues to expand its presence in the world of pharmaceuticals.
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P.O.BOX.851831AMMAN JO","customerAddress":"SYNO.257 258\/1, DNO.11-6\/56,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1711564200,"product":"(REJECTED AND RETURN) OLANZAPINE (FORM - 1) -PH EUR, MFG DT:JA N- 2024, RETEST DT:DEC-2024, BATCH NO: OZ P2401004.S\/B#78","address":"PLOT NO.1-A SEC-16A","city":"NOIDA (U.P) INDIA","supplier":"SANOFI","supplierCountry":"INDIA","foreign_port":"DUBAI","customer":"JUBILANT PHARMOVA","customerCountry":"INDIA","quantity":"17.90","actualQuantity":"17.9","unit":"KGS","unitRateFc":"1030","totalValueFC":"18651.1","currency":"USD","unitRateINR":"86520","date":"28-Mar-2024","totalValueINR":"1548708","totalValueInUsd":"18651.1","indian_port":"Bangalore Air","hs_no":"29349990","bill_no":"2789201","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"DUBAI","supplierAddress":"ESENTEPE MAH. BUYUKDERE CAD, 193 APT NO:193\/14 SISLI ISTANBUL Istanbul, , Turkey Turkey","customerAddress":"PLOT NO.1-A SEC-16A"}]
05-Jan-2021
29-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET;ORAL - 10MG

USFDA APPLICATION NUMBER - 20592

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DOSAGE - TABLET;ORAL - 15MG

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DOSAGE - TABLET;ORAL - 2.5MG

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DOSAGE - TABLET;ORAL - 20MG

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DOSAGE - TABLET;ORAL - 5MG

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DOSAGE - TABLET;ORAL - 7.5MG

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DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 10MG

USFDA APPLICATION NUMBER - 21086

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DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 15MG

USFDA APPLICATION NUMBER - 21086

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DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 20MG

USFDA APPLICATION NUMBER - 21086

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DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 5MG

USFDA APPLICATION NUMBER - 21086

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