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Chemistry

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Also known as: 508-02-1, Oleanic acid, Caryophyllin, Astrantiagenin c, Giganteumgenin c, Virgaureagenin b
Molecular Formula
C30H48O3
Molecular Weight
456.7  g/mol
InChI Key
MIJYXULNPSFWEK-GTOFXWBISA-N
FDA UNII
6SMK8R7TGJ

Oleanolic Acid
A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.
1 2D Structure

Oleanolic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
2.1.2 InChI
InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1
2.1.3 InChI Key
MIJYXULNPSFWEK-GTOFXWBISA-N
2.1.4 Canonical SMILES
CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C
2.1.5 Isomeric SMILES
C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O
2.2 Other Identifiers
2.2.1 UNII
6SMK8R7TGJ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hederins

2. Oleanane Triterpenes

3. Oleanol

4. Triterpenes, Oleanane

2.3.2 Depositor-Supplied Synonyms

1. 508-02-1

2. Oleanic Acid

3. Caryophyllin

4. Astrantiagenin C

5. Giganteumgenin C

6. Virgaureagenin B

7. 3beta-hydroxyolean-12-en-28-oic Acid

8. Oleonolic Acid

9. 3-beta-hydroxyolean-12-en-28-oic Acid

10. (4as,6ar,6as,6br,8ar,10s,12ar,14bs)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic Acid

11. Nsc-114945

12. (3-beta)-3-hydroxyolean-12-en-28-oic Acid

13. Nsc114945

14. 6smk8r7tgj

15. Olean-12-en-28-oic Acid, 3-hydroxy-, (3beta)-

16. Chebi:37659

17. Nsc 114945

18. (4as,6as,6br,8ar,10s,12ar,12br,14bs)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2h)-carboxylic Acid

19. Mfcd00064914

20. (4as,5s,6as,6br,8r,8ar,10s,12ar,12br,14bs)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2h-picene-4a-carboxylic Acid

21. 3-beta-hydroxy-olean-12-en-28-oicaci

22. Smr000445561

23. Ccris 6493

24. Oleanolic_acid

25. Chembl168

26. (3.beta.)-3-hydroxyolean-12-en-28-oic Acid

27. Einecs 208-081-6

28. Unii-6smk8r7tgj

29. Olean-12-en-28-oic Acid, 3-hydroxy-, (3.beta.)-

30. Oleanolic-acid

31. Gledigenin 1

32. Oleanolsa Currencyure

33. Oleanoic Acid Hydrate

34. Olean-12-en-28-oic Acid, 3.beta.-hydroxy-

35. Olean-12-en-28-oic Acid, 3beta-hydroxy-

36. Olean-12-en-28-oic Acid, 3-beta-hydroxy-

37. Oleanolic Acid, >=97%

38. Oleanolic Acid [mi]

39. Olean-12-en-28-oic Acid, 3-hydroxy-, (3b)-

40. Schembl71070

41. Mls000697656

42. Mls002207133

43. Oleanolic Acid [inci]

44. Olean-12-en-28-oic Acid, 3-hydroxy-, (3-beta)-

45. Gtpl3306

46. Oleanolic Acid [usp-rs]

47. Oleanolic Acid [who-dd]

48. Dtxsid50858790

49. Hms2232d15

50. Oleanolic Acid (oa)(compound 1)

51. Oleanolic Acid, Analytical Standard

52. Ex-a1991

53. Hy-n0156

54. Zinc3785416

55. Bdbm50346601

56. 3-beta-hydroxyolean-12-en-28-oate

57. 3beta-hydroxy-olean-12-en-28-oate

58. Akos015951416

59. Ac-8026

60. Ccg-208530

61. Cs-3800

62. Lmpr0106150004

63. 3.beta.-hydroxy-olean-12-en-28-oate

64. 3beta-hydroxy-olean-12-en-28-oic Acid

65. Ncgc00017222-10

66. (2s,5s,10s,18s,1r,14r,15r,20r)-18-hydroxy-1,2,8,8,15,19,19-heptamethylpentacyc Lo[12.8.0.0<2,11>.0<5,10>.0<15,20>]docos-11-ene-5-carboxylic Acid

67. As-35338

68. Bp-25410

69. (3-beta)-3-hydroxyolean-12-en-28-oate

70. (3?)-3-hydroxyolean-12-en-28-oic Acid

71. 3.beta.-hydroxy-olean-12-en-28-oic Acid

72. N1826

73. (3.beta.)-3-hydroxy-olean-12-en-28-oate

74. C17148

75. (3.beta.)-3-hydroxy-olean-12-en-28-oic Acid

76. (3.beta.)-3-beta-hydroxy-olean-12-en-28-oate

77. 3.beta.-hydroxyolean-12-en-28-oic Acid

78. 508o021

79. Q418628

80. Q-100572

81. (3.beta.)-3-beta-hydroxy-olean-12-en-28-oic Acid

82. Oleanolic Acid, Primary Pharmaceutical Reference Standard

83. C7ee6acc-7175-4947-b524-ff8479525da1

84. Oleanolic Acid (constituent Of Banaba Leaf) [dsc]

85. Oleanolic Acid (constituent Of Holy Basil Leaf) [dsc]

86. Oleanolic Acid, European Pharmacopoeia (ep) Reference Standard

87. Oleanolic Acid, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 456.7 g/mol
Molecular Formula C30H48O3
XLogP37.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass456.36034539 g/mol
Monoisotopic Mass456.36034539 g/mol
Topological Polar Surface Area57.5 Ų
Heavy Atom Count33
Formal Charge0
Complexity885
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

REF. STANDARDS & IMPURITIES

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PharmaCompass offers a list of Oleanolic Acid API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oleanolic Acid manufacturer or Oleanolic Acid supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Oleanolic Acid manufacturer or Oleanolic Acid supplier.

PharmaCompass also assists you with knowing the Oleanolic Acid API Price utilized in the formulation of products. Oleanolic Acid API Price is not always fixed or binding as the Oleanolic Acid Price is obtained through a variety of data sources. The Oleanolic Acid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Oleanolic Acid

Synonyms

508-02-1, Oleanic acid, Caryophyllin, Astrantiagenin c, Giganteumgenin c, Virgaureagenin b

Cas Number

508-02-1

Unique Ingredient Identifier (UNII)

6SMK8R7TGJ

About Oleanolic Acid

A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.

Oleanolic Acid Manufacturers

A Oleanolic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oleanolic Acid, including repackagers and relabelers. The FDA regulates Oleanolic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oleanolic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Oleanolic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Oleanolic Acid Suppliers

A Oleanolic Acid supplier is an individual or a company that provides Oleanolic Acid active pharmaceutical ingredient (API) or Oleanolic Acid finished formulations upon request. The Oleanolic Acid suppliers may include Oleanolic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of Oleanolic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Oleanolic Acid GMP

Oleanolic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oleanolic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oleanolic Acid GMP manufacturer or Oleanolic Acid GMP API supplier for your needs.

Oleanolic Acid CoA

A Oleanolic Acid CoA (Certificate of Analysis) is a formal document that attests to Oleanolic Acid's compliance with Oleanolic Acid specifications and serves as a tool for batch-level quality control.

Oleanolic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Oleanolic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oleanolic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Oleanolic Acid EP), Oleanolic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oleanolic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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