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ACTIVE PHARMA INGREDIENTS

7 API Suppliers, 2 USDMF, 1 KDMF, 2 NDC API, 6 Listed Suppliers

7 API Suppliers
2 USDMF
1 KDMF
2 NDC API
6 Listed Suppliers

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 2 FDA Orange Book, 12 Europe, 5 Canada

19 FDF Dossiers
2 FDA Orange Book
12 Europe
5 Canada

RELATED EXCIPIENT COMPANIES

2 Actylis, 1 Finar

relatedExcipients
2 Actylis
1 Finar

EXCIPIENTS BY APPLICATIONS

2 Solubilizers, 1 Parenteral

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2 Solubilizers
1 Parenteral

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 9 NEWS #PharmaBuzz

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1 DATA COMPILATION #PharmaFlow
9 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 11 Finished Drug Prices

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1 US Medicaid Prescriptions
11 Finished Drug Prices

PATENTS & EXCLUSIVITIES

21 US Patents, 4 Health Canada Patents

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21 US Patents
4 Health Canada Patents

Inke Olodaterol Hydrochloride

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

5,033,627

Annual Reports (USD Million)

Finished Drug Prices

3 RELATED EXCIPIENT COMPANIES

3EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 869477-96-3, Olodaterol hcl, Striverdi respimat, Bi 1744 cl, Bi-1744-cl, Bi 1744 hydrochloride

Molecular Formula

C₂₁H₂₇ClN₂O₅

Molecular Weight

422.9 g/mol

InChI Key

KCEHVJZZIGJAAW-FERBBOLQSA-N

FDA UNII

65R445W3V9

1 2D Structure

Olodaterol Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

6-hydroxy-8-[(1R)-1-hydroxy-2-[[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one;hydrochloride

2.1.2 InChI

InChI=1S/C21H26N2O5.ClH/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17;/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26);1H/t18-;/m0./s1

2.1.3 InChI Key

KCEHVJZZIGJAAW-FERBBOLQSA-N

2.1.4 Canonical SMILES

CC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O.Cl

2.1.5 Isomeric SMILES

CC(C)(CC1=CC=C(C=C1)OC)NC[C@@H](C2=C3C(=CC(=C2)O)NC(=O)CO3)O.Cl

2.2 Other Identifiers

2.2.1 UNII

65R445W3V9

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 6-hydroxy-8-(1-hydroxy-2-((2-(4-methoxyphenyl)-1,1-dimethylethyl)amino)ethyl)-2h-1,4-benzoxazin-3(4h)-one

2. Bi 1744 Cl

3. Bi-1744 Cl

4. Olodaterol

5. Striverdi Respimat

2.3.2 Depositor-Supplied Synonyms

1. 869477-96-3

2. Olodaterol Hcl

3. Striverdi Respimat

4. Bi 1744 Cl

5. Bi-1744-cl

6. Bi 1744 Hydrochloride

7. Bi-1744 Cl

8. Olodaterol Hydrochloride [usan]

9. Chebi:83309

10. Olodaterol (hydrochloride)

11. 65r445w3v9

12. 2h-1,4-benzoxazin-3(4h)-one, 6-hydroxy-8-((1r)-1-hydroxy-2-((2-(4-methoxyphenyl)- 1,1-dimethylethyl)amino)ethyl)-, Hydrochloride (1:1)

13. 6-hydroxy-8-((1r)-1-hydroxy-2-((2-(4-methoxyphenyl)-1,1-dimethylethyl)amino)ethyl)- 2h-1,4-benzoxazin-3(4h)-one Hydrochloride

14. Striverdi Respimat (tn)

15. 6-hydroxy-8-[(1r)-1-hydroxy-2-[[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino]ethyl]-4h-1,4-benzoxazin-3-one;hydrochloride

16. Unii-65r445w3v9

17. (r)-6-hydroxy-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2h-benzo[b][1,4]oxazin-3(4h)-one Hydrochloride

18. 869477-96-3 (hcl)

19. Schembl560669

20. Bi-1744 Hcl

21. Chembl2105743

22. Dtxsid901027733

23. Amy16778

24. Bcp16765

25. Ex-a2815

26. Olodaterol(bi-1744) Hydrochloride

27. Bdbm50538807

28. Hy-14301a

29. Olodaterol Hydrochloride (jan/usan)

30. Olodaterol Hydrochloride [mi]

31. S5925

32. Akos030524628

33. Olodaterol Hydrochloride [vandf]

34. Olodaterol Hydrochloride [who-dd]

35. Ac-29884

36. As-58291

37. Cs-0021887

38. Olodaterol Hydrochloride [orange Book]

39. D10020

40. A862976

41. Q27156746

42. 2h-1,4-benzoxazin-3(4h)-one, 6-hydroxy-8-[(1r)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-, Hydrochloride (1:1)

43. 6-hydroxy-8-[(1r)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl]-2h-1,4-benzoxazin-3(4h)-one Hydrochloride

44. N-[(2r)-2-hydroxy-2-(6-hydroxy-3-oxo-3,4-dihydro-2h-1,4-benzoxazin-8-yl)ethyl]-1-(4-methoxyphenyl)-2-methylpropan-2-aminium Chloride

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₇ClN₂O₅
Molecular Weight	422.9 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	422.1608497 g/mol
Monoisotopic Mass	422.1608497 g/mol
Topological Polar Surface Area	100 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	521
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2