Find Olprinone manufacturers, exporters & distributors on PharmaCompass

Olprinone

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 Listed Suppliers

2 API Suppliers
2 Listed Suppliers

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

MARKET PLACE

1 APIs

marketPlace
1 APIs

REF. STANDARDS & IMPURITIES

2 Others

otherSolutions
2 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

2INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 106730-54-5, Loprinone, Olprinone [inn], 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1h-pyridine-3-carbonitrile, 4y8bmi9ygc, Olprinone (inn)

Molecular Formula

C₁₄H₁₀N₄O

Molecular Weight

250.25 g/mol

InChI Key

JPAWFIIYTJQOKW-UHFFFAOYSA-N

FDA UNII

4Y8BMI9YGC

1 2D Structure

Olprinone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile

2.1.2 InChI

InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)

2.1.3 InChI Key

JPAWFIIYTJQOKW-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2

2.2 Other Identifiers

2.2.1 UNII

4Y8BMI9YGC

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1,2-dihydro-6-methyl-2-oxo-5-(imidazo(1,2-a)pyridin-6-yl)-3-pyridinecarbonitrile

2. E 1020

3. E-1020

4. Loprinone Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 106730-54-5

2. Loprinone

3. Olprinone [inn]

4. 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1h-pyridine-3-carbonitrile

5. 4y8bmi9ygc

6. Olprinone (inn)

7. 5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

8. 5-{imidazo[1,2-a]pyridin-6-yl}-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

9. Loprinone [mi]

10. Unii-4y8bmi9ygc

11. Olprinone [who-dd]

12. Schembl27661

13. Chembl1474900

14. Dtxsid1048461

15. Chebi:135019

16. Bcp09781

17. Hy-14254a

18. S5539

19. Zinc38192538

20. 1,2-dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile

21. Ccg-266964

22. Cs-1190

23. Sdccgsbi-0633821.p001

24. Ncgc00162385-01

25. Ncgc00162385-02

26. Ncgc00162385-03

27. Ncgc00162385-05

28. Ncgc00162385-10

29. Ac-35198

30. As-73630

31. Db-040705

32. 4606a

33. Ft-0631041

34. C71263

35. D08294

36. Q7088538

37. Brd-k20745393-001-01-4

38. 1,2-dihydro-5-(imidazo[1,2-a]-pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile

39. 1,2-dihydro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile

40. 1,2-dihydro-5-imidazo(1,2-.alpha.)pyridin-6-yl-6-methyl-2-oxonicotinonitrile

41. 1,2-dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile.

42. 1,2-dihydro-6-methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-3-pyridine Carbonitrile

43. 1,2-dihydro-6-methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-3-pyridinecarbonitrile

44. 1,2-dihydro-6-methyl-5-(imidazo[1,2-a]pyridin-6-yl)-2-oxo-3-pyridinecarbonitrile

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₁₀N₄O
Molecular Weight	250.25 g/mol
XLogP3	1.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	250.08546096 g/mol
Monoisotopic Mass	250.08546096 g/mol
Topological Polar Surface Area	70.2 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	525
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

Phosphodiesterase 3 Inhibitors

Compounds that specifically inhibit PHOSPHODIESTERASE 3. (See all compounds classified as Phosphodiesterase 3 Inhibitors.)

API SUPPLIERS