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Chemistry

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Also known as: 106730-54-5, Loprinone, Olprinone [inn], 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1h-pyridine-3-carbonitrile, 4y8bmi9ygc, Olprinone (inn)
Molecular Formula
C14H10N4O
Molecular Weight
250.25  g/mol
InChI Key
JPAWFIIYTJQOKW-UHFFFAOYSA-N
FDA UNII
4Y8BMI9YGC

Olprinone
1 2D Structure

Olprinone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
2.1.2 InChI
InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)
2.1.3 InChI Key
JPAWFIIYTJQOKW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2
2.2 Other Identifiers
2.2.1 UNII
4Y8BMI9YGC
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,2-dihydro-6-methyl-2-oxo-5-(imidazo(1,2-a)pyridin-6-yl)-3-pyridinecarbonitrile

2. E 1020

3. E-1020

4. Loprinone Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 106730-54-5

2. Loprinone

3. Olprinone [inn]

4. 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1h-pyridine-3-carbonitrile

5. 4y8bmi9ygc

6. Olprinone (inn)

7. 5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

8. 5-{imidazo[1,2-a]pyridin-6-yl}-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

9. Loprinone [mi]

10. Unii-4y8bmi9ygc

11. Olprinone [who-dd]

12. Schembl27661

13. Chembl1474900

14. Dtxsid1048461

15. Chebi:135019

16. Bcp09781

17. Hy-14254a

18. S5539

19. Zinc38192538

20. 1,2-dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile

21. Ccg-266964

22. Cs-1190

23. Sdccgsbi-0633821.p001

24. Ncgc00162385-01

25. Ncgc00162385-02

26. Ncgc00162385-03

27. Ncgc00162385-05

28. Ncgc00162385-10

29. Ac-35198

30. As-73630

31. Db-040705

32. 4606a

33. Ft-0631041

34. C71263

35. D08294

36. Q7088538

37. Brd-k20745393-001-01-4

38. 1,2-dihydro-5-(imidazo[1,2-a]-pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile

39. 1,2-dihydro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile

40. 1,2-dihydro-5-imidazo(1,2-.alpha.)pyridin-6-yl-6-methyl-2-oxonicotinonitrile

41. 1,2-dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile.

42. 1,2-dihydro-6-methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-3-pyridine Carbonitrile

43. 1,2-dihydro-6-methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-3-pyridinecarbonitrile

44. 1,2-dihydro-6-methyl-5-(imidazo[1,2-a]pyridin-6-yl)-2-oxo-3-pyridinecarbonitrile

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 250.25 g/mol
Molecular Formula C14H10N4O
XLogP31.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass250.08546096 g/mol
Monoisotopic Mass250.08546096 g/mol
Topological Polar Surface Area70.2 Ų
Heavy Atom Count19
Formal Charge0
Complexity525
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)


Phosphodiesterase 3 Inhibitors

Compounds that specifically inhibit PHOSPHODIESTERASE 3. (See all compounds classified as Phosphodiesterase 3 Inhibitors.)


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ABOUT THIS PAGE

Olprinone Manufacturers

A Olprinone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Olprinone, including repackagers and relabelers. The FDA regulates Olprinone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Olprinone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Olprinone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Olprinone Suppliers

A Olprinone supplier is an individual or a company that provides Olprinone active pharmaceutical ingredient (API) or Olprinone finished formulations upon request. The Olprinone suppliers may include Olprinone API manufacturers, exporters, distributors and traders.

click here to find a list of Olprinone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Olprinone GMP

Olprinone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Olprinone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Olprinone GMP manufacturer or Olprinone GMP API supplier for your needs.

Olprinone CoA

A Olprinone CoA (Certificate of Analysis) is a formal document that attests to Olprinone's compliance with Olprinone specifications and serves as a tool for batch-level quality control.

Olprinone CoA mostly includes findings from lab analyses of a specific batch. For each Olprinone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Olprinone may be tested according to a variety of international standards, such as European Pharmacopoeia (Olprinone EP), Olprinone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Olprinone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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