Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Virtual Booth

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

4 API Suppliers, 1 USDMF, 3 Listed Suppliers

4 API Suppliers
1 USDMF
3 Listed Suppliers

INTERMEDIATES

3 Intermediates Suppliers

3 Intermediates Suppliers

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

media
1 DATA COMPILATION #PharmaFlow

MARKET PLACE

2 APIs

marketPlace
2 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

3INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 1226781-44-7, Mk-3102, Mk3102, (2r,3s,5r)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2h,4h,6h)-yl)tetrahydro-2h-pyran-3-amine, Cvp59q4je1, Unii-cvp59q4je1

Molecular Formula

C₁₇H₂₀F₂N₄O₃S

Molecular Weight

398.4 g/mol

InChI Key

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

FDA UNII

CVP59Q4JE1

Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.

1 2D Structure

Omarigliptin

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-methylsulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)oxan-3-amine

2.1.2 InChI

InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1

2.1.3 InChI Key

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

2.1.4 Canonical SMILES

CS(=O)(=O)N1C=C2CN(CC2=N1)C3CC(C(OC3)C4=C(C=CC(=C4)F)F)N

2.1.5 Isomeric SMILES

CS(=O)(=O)N1C=C2CN(CC2=N1)[C@@H]3C[C@@H]([C@H](OC3)C4=C(C=CC(=C4)F)F)N

2.2 Other Identifiers

2.2.1 UNII

CVP59Q4JE1

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)-2,6-dihydropyrrolo(3,4-c)pyrazol-5(4h)-yl)tetrahydro-2h-pyran-3-amine

2. Mk-3102

2.3.2 Depositor-Supplied Synonyms

1. 1226781-44-7

2. Mk-3102

3. Mk3102

4. (2r,3s,5r)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2h,4h,6h)-yl)tetrahydro-2h-pyran-3-amine

5. Cvp59q4je1

6. Unii-cvp59q4je1

7. (2r,3s,5r)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4h)-yl)tetrahydro-2h-pyran-3-amine

8. (2r,3s,5r)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4h)-yl]tetrahydro-2h-pyran-3-amine

9. 2h-pyran-3-amine, 2-(2,5-difluorophenyl)-5-(2,6-dihydro-2-(methylsulfonyl)pyrrolo(3,4-c)pyrazol-5(4h)-yl)tetrahydro-,(2r,3s,5r)-

10. (2r,3s,5r)-2-(2,5-difluorophenyl)-5-(2-methylsulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)oxan-3-amine

11. Omarigliptin [usan]

12. Omarigliptin [usan:inn]

13. Omarigliptin [mi]

14. Omarigliptin [inn]

15. Omarigliptin [jan]

16. Omarigliptin (mk-3102)

17. Omarigliptin [who-dd]

18. Schembl827590

19. Ambz0104

20. Gtpl8402

21. Omarigliptin (jan/usan/inn)

22. Chembl2105762

23. Dtxsid70153678

24. Ex-a395

25. Chebi:134735

26. Bdbm50003020

27. Mfcd22573261

28. Nsc802900

29. S8565

30. Zinc84758480

31. Akos025289528

32. Am85511

33. Ccg-268634

34. Cs-3948

35. Db11992

36. Ds-7574

37. Nsc-802900

38. Pb39113

39. Ncgc00480770-01

40. (2r,3s,5r)-2-(2,5-difluorophenyl)-5-(2-(methanesulfonyl)-2,6-dihydropyrrolo(3,4- C)pyrazol-5(4h)-yl)oxan-3-amine

41. (2r,3s,5r)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)-2,6-dihydropyrrolo(3,4- C)pyrazol-5(4h)-yl)tetrahydro-2h-pyran-3-amine

42. 2h-pyran-3-amine, 2-(2,5-difluorophenyl)-5-(2,6-dihydro-2-(methylsulfonyl)pyrrolo(3,4- C)pyrazol-5(4h)-yl)tetrahydro-, (2r,3s,5r)-

43. Ac-28992

44. Hy-15981

45. D10317

46. L10002

47. J-690074

48. Q21098979

49. (2r,3s,5r)-2-(2,5-difluorophenyl)-5[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4h)-yl]tetrahydro-2h-pyran-3-amine

50. 2h-pyran-3-amine, 2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4h)-yl]tetrahydro-, (2r,3s,5r)-

2.4 Create Date

2010-07-06

3 Chemical and Physical Properties

Molecular Formula	C₁₇H₂₀F₂N₄O₃S
Molecular Weight	398.4 g/mol
XLogP3	0.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	3
Exact Mass	398.12241801 g/mol
Monoisotopic Mass	398.12241801 g/mol
Topological Polar Surface Area	98.8 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	649
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1