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Chemistry

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Also known as: Omoconazole nitrate [usan], 83621-06-1, Omoconazole mononitrate, 15lty5sty6, 1h-imidazole, 1-(2-(2-(4-chlorophenoxy)ethoxy)-2-(2,4-dichlorophenyl)-1-methylethenyl)-, (z)-, mononitrate, Fongarex
Molecular Formula
C20H18Cl3N3O5
Molecular Weight
486.7  g/mol
InChI Key
BNDOPUYTWJQTOE-VSOKSMTPSA-N
FDA UNII
15LTY5STY6

Omoconazole
Omoconazole Nitrate is the nitrate salt form of omoconazole, a topical imidazole derivative with antifungal activity against Candida albicans, Malassezia furfur and dematophytes.
1 2D Structure

Omoconazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[(Z)-1-[2-(4-chlorophenoxy)ethoxy]-1-(2,4-dichlorophenyl)prop-1-en-2-yl]imidazole;nitric acid
2.1.2 InChI
InChI=1S/C20H17Cl3N2O2.HNO3/c1-14(25-9-8-24-13-25)20(18-7-4-16(22)12-19(18)23)27-11-10-26-17-5-2-15(21)3-6-17;2-1(3)4/h2-9,12-13H,10-11H2,1H3;(H,2,3,4)/b20-14-;
2.1.3 InChI Key
BNDOPUYTWJQTOE-VSOKSMTPSA-N
2.1.4 Canonical SMILES
CC(=C(C1=C(C=C(C=C1)Cl)Cl)OCCOC2=CC=C(C=C2)Cl)N3C=CN=C3.[N+](=O)(O)[O-]
2.1.5 Isomeric SMILES
C/C(=C(\C1=C(C=C(C=C1)Cl)Cl)/OCCOC2=CC=C(C=C2)Cl)/N3C=CN=C3.[N+](=O)(O)[O-]
2.2 Other Identifiers
2.2.1 UNII
15LTY5STY6
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Afongan

2. Cm 8282

3. Cm-8282

4. Fongamil

5. Fongarex

6. Omoconazole

7. Omoconazole Mononitrate

2.3.2 Depositor-Supplied Synonyms

1. Omoconazole Nitrate [usan]

2. 83621-06-1

3. Omoconazole Mononitrate

4. 15lty5sty6

5. 1h-imidazole, 1-(2-(2-(4-chlorophenoxy)ethoxy)-2-(2,4-dichlorophenyl)-1-methylethenyl)-, (z)-, Mononitrate

6. Fongarex

7. 1-[(z)-1-[2-(4-chlorophenoxy)ethoxy]-1-(2,4-dichlorophenyl)prop-1-en-2-yl]imidazole;nitric Acid

8. Unii-15lty5sty6

9. Anfongan

10. Fangorex

11. Fongamil

12. Omotrex

13. Afonga

14. Omoconazolnitrat

15. Ccris 8167

16. (z)-1-(2,4-dichloro-beta-(2-(p-chlorophenoxy)ethoxy)-alpha-methylstyryl)imidazole Mononitrate

17. (z)-1-(2-(2-(4-chlorophenoxy)ethoxy)-2-(2,4-dichlorophenyl)-1-methylethenyl)-1h-imidazole Hno3

18. Schembl1643133

19. Schembl1643135

20. Sgd-12878

21. Chembl2107140

22. Omoconazole Nitrate [mi]

23. Chebi:31935

24. Omoconazole Nitrate (jan/usan)

25. Hoc-155

26. Omoconazole Nitrate [jan]

27. Omoconazole Nitrate [mart.]

28. Omoconazole Nitrate [who-dd]

29. Cm-8282

30. D01664

31. Q27251733

32. (z)-1-(2,4-dichloro-.beta.-(2-(p-chlorophenoxy)ethoxy)-.alpha.-methylstyryl)imidazole Mononitrate

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 486.7 g/mol
Molecular Formula C20H18Cl3N3O5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass485.031204 g/mol
Monoisotopic Mass485.031204 g/mol
Topological Polar Surface Area102 Ų
Heavy Atom Count31
Formal Charge0
Complexity522
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)


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ABOUT THIS PAGE

Omoconazole Manufacturers

A Omoconazole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Omoconazole, including repackagers and relabelers. The FDA regulates Omoconazole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Omoconazole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Omoconazole Suppliers

A Omoconazole supplier is an individual or a company that provides Omoconazole active pharmaceutical ingredient (API) or Omoconazole finished formulations upon request. The Omoconazole suppliers may include Omoconazole API manufacturers, exporters, distributors and traders.

click here to find a list of Omoconazole suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Omoconazole USDMF

A Omoconazole DMF (Drug Master File) is a document detailing the whole manufacturing process of Omoconazole active pharmaceutical ingredient (API) in detail. Different forms of Omoconazole DMFs exist exist since differing nations have different regulations, such as Omoconazole USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Omoconazole DMF submitted to regulatory agencies in the US is known as a USDMF. Omoconazole USDMF includes data on Omoconazole's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Omoconazole USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Omoconazole suppliers with USDMF on PharmaCompass.

Omoconazole GMP

Omoconazole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Omoconazole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Omoconazole GMP manufacturer or Omoconazole GMP API supplier for your needs.

Omoconazole CoA

A Omoconazole CoA (Certificate of Analysis) is a formal document that attests to Omoconazole's compliance with Omoconazole specifications and serves as a tool for batch-level quality control.

Omoconazole CoA mostly includes findings from lab analyses of a specific batch. For each Omoconazole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Omoconazole may be tested according to a variety of international standards, such as European Pharmacopoeia (Omoconazole EP), Omoconazole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Omoconazole USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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