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Chemistry

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Also known as: Orgotein, bovine, Orgotein [inn], Orgotein [usan], Orgotein [mart.], Orgotein [who-dd], Orgotein [green book]
Molecular Formula
Cu4Zn4+16
Molecular Weight
515.7  g/mol
InChI Key
TUGDLVFMIQZYPA-UHFFFAOYSA-N

Orgotein
1 2D Structure

Orgotein

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
tetracopper;tetrazinc
2.1.2 InChI
InChI=1S/4Cu.4Zn/q8*+2
2.1.3 InChI Key
TUGDLVFMIQZYPA-UHFFFAOYSA-N
2.1.4 Canonical SMILES
[Cu+2].[Cu+2].[Cu+2].[Cu+2].[Zn+2].[Zn+2].[Zn+2].[Zn+2]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Bovine Copper-zinc Superoxide Dismutase

2. Ontose

3. Ontosein

4. Ormetein

5. Palosein

6. Peroxinorm

7. Superoxide Dismutase (bovine)

2.2.2 Depositor-Supplied Synonyms

1. Orgotein, Bovine

2. Orgotein [inn]

3. Orgotein [usan]

4. Orgotein [mart.]

5. Orgotein [who-dd]

6. Orgotein [green Book]

7. Ontosein

8. Ormetein

9. Palosein

10. Superoxide Dismutase (bovine)

11. Copper-zinc Superoxide Dismutase

12. Superoxide Dismutase, Bovine (cu-zn)

13. Orgotein [usan:inn]

14. Unii-pke82w49v1

15. Pke82w49v1

16. Bovine Copper-zinc Superoxide Dismutase

17. 1569268-91-2

2.3 Create Date
2014-03-02
3 Chemical and Physical Properties
Molecular Weight 515.7 g/mol
Molecular Formula Cu4Zn4+16
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count0
Exact Mass515.42574 g/mol
Monoisotopic Mass507.43496 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count8
Formal Charge16
Complexity0
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count8
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


4.2 ATC Code

M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AX - Other antiinflammatory and antirheumatic agents, non-steroids

M01AX14 - Orgotein


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