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Chemistry

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Also known as: Tak-653, 1358751-06-0, Pyrazino(2,1-c)(1,2,4)thiadiazine, 9-(4-(cyclohexyloxy)phenyl)-3,4-dihydro-7-methyl-, 2,2-dioxide, Unii-9e3toe5riz, Schembl622985, Chembl4594403
Molecular Formula
C19H23N3O3S
Molecular Weight
373.5  g/mol
InChI Key
PXJBHEHFVQVDDS-UHFFFAOYSA-N
FDA UNII
9E3TOE5RIZ

Osavampator
TAK-653 is under investigation in clinical trial NCT03312894 (Efficacy and Safety of TAK-653 in Treatment-resistant Depression).
1 2D Structure

Osavampator

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
9-(4-cyclohexyloxyphenyl)-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide
2.1.2 InChI
InChI=1S/C19H23N3O3S/c1-14-13-22-11-12-26(23,24)21-19(22)18(20-14)15-7-9-17(10-8-15)25-16-5-3-2-4-6-16/h7-10,13,16H,2-6,11-12H2,1H3
2.1.3 InChI Key
PXJBHEHFVQVDDS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CN2CCS(=O)(=O)N=C2C(=N1)C3=CC=C(C=C3)OC4CCCCC4
2.2 Other Identifiers
2.2.1 UNII
9E3TOE5RIZ
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Tak-653

2. 1358751-06-0

3. Pyrazino(2,1-c)(1,2,4)thiadiazine, 9-(4-(cyclohexyloxy)phenyl)-3,4-dihydro-7-methyl-, 2,2-dioxide

4. Unii-9e3toe5riz

5. Schembl622985

6. Chembl4594403

7. Ex-a6607

8. Hy-115864

9. Cs-0370518

10. 9-[4-(cyclohexyloxy)phenyl]-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide

2.4 Create Date
2012-03-05
3 Chemical and Physical Properties
Molecular Weight 373.5 g/mol
Molecular Formula C19H23N3O3S
XLogP32.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass373.14601278 g/mol
Monoisotopic Mass373.14601278 g/mol
Topological Polar Surface Area79.7 Ų
Heavy Atom Count26
Formal Charge0
Complexity722
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1358751-06-0 / TAK-653 API manufacturers, exporters & distributors?

TAK-653 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of TAK-653 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right TAK-653 manufacturer or TAK-653 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred TAK-653 manufacturer or TAK-653 supplier.

PharmaCompass also assists you with knowing the TAK-653 API Price utilized in the formulation of products. TAK-653 API Price is not always fixed or binding as the TAK-653 Price is obtained through a variety of data sources. The TAK-653 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

TAK-653

Synonyms

1358751-06-0, Pyrazino(2,1-c)(1,2,4)thiadiazine, 9-(4-(cyclohexyloxy)phenyl)-3,4-dihydro-7-methyl-, 2,2-dioxide, Unii-9e3toe5riz, Schembl622985, Chembl4594403, Ex-a6607

Cas Number

1358751-06-0

Unique Ingredient Identifier (UNII)

9E3TOE5RIZ

About TAK-653

TAK-653 is under investigation in clinical trial NCT03312894 (Efficacy and Safety of TAK-653 in Treatment-resistant Depression).

Osavampator Manufacturers

A Osavampator manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Osavampator, including repackagers and relabelers. The FDA regulates Osavampator manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Osavampator API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Osavampator Suppliers

A Osavampator supplier is an individual or a company that provides Osavampator active pharmaceutical ingredient (API) or Osavampator finished formulations upon request. The Osavampator suppliers may include Osavampator API manufacturers, exporters, distributors and traders.

Osavampator GMP

Osavampator Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Osavampator GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Osavampator GMP manufacturer or Osavampator GMP API supplier for your needs.

Osavampator CoA

A Osavampator CoA (Certificate of Analysis) is a formal document that attests to Osavampator's compliance with Osavampator specifications and serves as a tool for batch-level quality control.

Osavampator CoA mostly includes findings from lab analyses of a specific batch. For each Osavampator CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Osavampator may be tested according to a variety of international standards, such as European Pharmacopoeia (Osavampator EP), Osavampator JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Osavampator USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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