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1. Methylphenylisoxazolyl Penicillin
2. Oxacillin Sodium
3. Oxacillin, Monosodium Salt, Anhydrous
4. Oxacillin, Monosodium Salt, Monohydrate
5. Oxacillin, Sodium
6. Oxazocilline
7. Penicillin, Methylphenylisoxazolyl
8. Prostaphlin
9. Sodium Oxacillin
10. Sodium, Oxacillin
1. Oxazocillin
2. 66-79-5
3. Oxazocilline
4. Mpi-penicillin
5. Oxacilina
6. Bactocill
7. Prostaphlin
8. Oxacillin Sodium
9. 5-methyl-3-phenyl-4-isoxazolyl-penicillin
10. Oxacillin (inn)
11. Chebi:7809
12. (2s,5r,6r)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
13. (5-methyl-3-phenyl-4-isoxazolyl)penicillin
14. Penicillin, (5-methyl-3-phenyl-4-isoxazolyl)-
15. 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanic Acid
16. Uh95vd7v76
17. (2s,5r,6r)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
18. Ossacillina
19. Oxacilline
20. Oxacillinum
21. Prostaphlyn
22. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-, (2s,5r,6r)-
23. Ossacillina [dcit]
24. Oxacillin [inn]
25. Mpi-pc
26. Oxacillin [inn:ban]
27. Oxacilina [inn-spanish]
28. Oxacilline [inn-french]
29. Oxacillinum [inn-latin]
30. 1173-88-2
31. Oxacilina (tn)
32. Einecs 200-635-5
33. Unii-uh95vd7v76
34. Oxacillin,(s)
35. (2s,5r,6r)-3,3-dimethyl-6-[(5-methyl-3-phenyl-isoxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
36. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, (2s-(2alpha,5alpha,6beta))-
37. Oxacillin [mi]
38. Oxacillin [vandf]
39. Chembl819
40. Epitope Id:181859
41. Oxacillin [mart.]
42. Oxacillin [who-dd]
43. Schembl3817
44. Dtxsid8023397
45. Gtpl10943
46. Hy-b0925a
47. Phenylisoxazole-4-carboxamido)-7-
48. Zinc3875439
49. Bdbm50350483
50. Db00713
51. 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylic Acid
52. (2s,5r,6r)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
53. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamide)-7-oxo-
54. 5-methyl-3-phenyl-4-isooxazolylpenicillin
55. Oxo-4-thia-1-azabicyclo[3.2.0]heptane-
56. Cs-0013715
57. C07334
58. D08307
59. (2s,5r,6r)-3,3-dimethyl-6-(5-methyl-3-
60. Q418725
61. Brd-k96786677-236-01-6
62. Brd-k96786677-236-02-4
63. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-,(2s,5r,6r)-
64. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, (2s-(2.alpha.,5.alpha.,6.beta.))-
| Molecular Weight | 401.4 g/mol |
|---|---|
| Molecular Formula | C19H19N3O5S |
| XLogP3 | 2.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 401.10454189 g/mol |
| Monoisotopic Mass | 401.10454189 g/mol |
| Topological Polar Surface Area | 138 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 681 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 2 | |
|---|---|
| Drug Name | Oxacillin sodium |
| Drug Label | Oxacillin for Injection, USP is a semisynthetic penicillin antibiotic derived from the penicillin nucleus, 6-amino-penicillanic acid. It is resistant to inactivation by the enzyme penicillinase (beta-lactamase). It is the sodium salt in parenteral do... |
| Active Ingredient | Oxacillin sodium |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | eq 2gm base/vial; eq 10gm base/vial; eq 1gm base/vial |
| Market Status | Prescription |
| Company | Aurobindo Pharma; Sandoz; Sagent Pharms; Agila Speclts |
| 2 of 2 | |
|---|---|
| Drug Name | Oxacillin sodium |
| Drug Label | Oxacillin for Injection, USP is a semisynthetic penicillin antibiotic derived from the penicillin nucleus, 6-amino-penicillanic acid. It is resistant to inactivation by the enzyme penicillinase (beta-lactamase). It is the sodium salt in parenteral do... |
| Active Ingredient | Oxacillin sodium |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | eq 2gm base/vial; eq 10gm base/vial; eq 1gm base/vial |
| Market Status | Prescription |
| Company | Aurobindo Pharma; Sandoz; Sagent Pharms; Agila Speclts |
Used in the treatment of resistant staphylococci infections.
Oxacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Oxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Oxacillin results from the inhibition of cell wall synthesis and is mediated through Oxacillin binding to penicillin binding proteins (PBPs). Oxacillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Anti-Bacterial Agents
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01C - Beta-lactam antibacterials, penicillins
J01CF - Beta-lactamase resistant penicillins
J01CF04 - Oxacillin
Route of Elimination
Oxacillin Sodium is rapidly excreted as unchanged drug in the urine by glomerular filtration and active tubular secretion.
20 to 30 minutes
By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Oxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Oxacillin interferes with an autolysin inhibitor.
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Average Price (USD/KGS) |
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US Medicaid Prescriptions
Company :
Oxacillin In Dextrose(Iso-Osm)
Drug Cost (USD) : 36,070
Year : 2022
Prescribers : 15
Prescriptions : 43
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Company :
Oxacillin In Dextrose(Iso-Osm)
Drug Cost (USD) : 156,050
Year : 2021
Prescribers : 57
Prescriptions : 181
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Company :
Oxacillin In Dextrose(Iso-Osm)
Drug Cost (USD) : 227,933
Year : 2020
Prescribers : 64
Prescriptions : 252
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Company :
OXACILLIN SODIUM/DEXTROSE,ISO
Drug Cost (USD) : 640,885
Year : 2014
Prescribers : 206
Prescriptions : 810
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REF. STANDARDS & IMPURITIES
ABOUT THIS PAGE
A Oxacillin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxacillin, including repackagers and relabelers. The FDA regulates Oxacillin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxacillin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Oxacillin supplier is an individual or a company that provides Oxacillin active pharmaceutical ingredient (API) or Oxacillin finished formulations upon request. The Oxacillin suppliers may include Oxacillin API manufacturers, exporters, distributors and traders.
click here to find a list of Oxacillin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Oxacillin DMF (Drug Master File) is a document detailing the whole manufacturing process of Oxacillin active pharmaceutical ingredient (API) in detail. Different forms of Oxacillin DMFs exist exist since differing nations have different regulations, such as Oxacillin USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Oxacillin DMF submitted to regulatory agencies in the US is known as a USDMF. Oxacillin USDMF includes data on Oxacillin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Oxacillin USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Oxacillin suppliers with USDMF on PharmaCompass.
Oxacillin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Oxacillin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxacillin GMP manufacturer or Oxacillin GMP API supplier for your needs.
A Oxacillin CoA (Certificate of Analysis) is a formal document that attests to Oxacillin's compliance with Oxacillin specifications and serves as a tool for batch-level quality control.
Oxacillin CoA mostly includes findings from lab analyses of a specific batch. For each Oxacillin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Oxacillin may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxacillin EP), Oxacillin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxacillin USP).
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