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Chemistry

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Also known as: Oxacillin sodium salt, 1173-88-2, Oxabel, Prostaphlin, Bactocill, Sodium oxacillin
Molecular Formula
C19H18N3NaO5S
Molecular Weight
423.4  g/mol
InChI Key
VDUVBBMAXXHEQP-SLINCCQESA-M
FDA UNII
4TWD2995UP

Oxacillin Sodium
An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.
1 2D Structure

Oxacillin Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
2.1.2 InChI
InChI=1S/C19H19N3O5S.Na/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22;/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26);/q;+1/p-1/t13-,14+,17-;/m1./s1
2.1.3 InChI Key
VDUVBBMAXXHEQP-SLINCCQESA-M
2.1.4 Canonical SMILES
CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]
2.1.5 Isomeric SMILES
CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].[Na+]
2.2 Other Identifiers
2.2.1 UNII
4TWD2995UP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Methylphenylisoxazolyl Penicillin

2. Oxacillin

3. Oxacillin, Monosodium Salt, Anhydrous

4. Oxacillin, Monosodium Salt, Monohydrate

5. Oxacillin, Sodium

6. Oxazocilline

7. Penicillin, Methylphenylisoxazolyl

8. Prostaphlin

9. Sodium Oxacillin

10. Sodium, Oxacillin

2.3.2 Depositor-Supplied Synonyms

1. Oxacillin Sodium Salt

2. 1173-88-2

3. Oxabel

4. Prostaphlin

5. Bactocill

6. Sodium Oxacillin

7. Oxacillin Sodium Anhydrous

8. Bristopen

9. Micropenin

10. Resistopen

11. Staphcillin V

12. Oxacillin (sodium Salt)

13. Chebi:52134

14. 4twd2995up

15. Oxabel Sodium Salt

16. Monosodium Oxacillin

17. Sq-16423

18. Anhydrous Oxacillin Sodium

19. Sodium Methylphenylisoaxazolylpenicillin

20. Oxacillin Sodium (van)

21. Sodium (2s,5r,6r)-3,3-dimethyl-6-(5-methyl-3-phenylisoxazole-4-carboxamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

22. 5-methyl-3-phenyl-4-isoxazolyl Penicillin, Sodium

23. Nsc-527712

24. Brl 1400

25. Oxacillin Sodium [usp]

26. 7240-38-2

27. Einecs 214-636-3

28. Nsc 527712

29. Unii-4twd2995up

30. Bactocill In Plastic Container

31. Ncgc00183361-01

32. Chembl693

33. Dsstox_cid_28906

34. Dsstox_rid_83174

35. Dsstox_gsid_48980

36. Schembl41165

37. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, Monosodium Salt, (2s-(2alpha,5alpha,6beta))-

38. Mls000069542

39. Dtxsid9048980

40. Oxacillin Sodium [who-dd]

41. Hms3714g11

42. Hy-b0925

43. Sodium;(2s,5r,6r)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

44. Tox21_113439

45. Bdbm50248015

46. Akos015896457

47. Ccg-220675

48. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, Monosodium Salt, (2s,5r,6r)-

49. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamido)-7-oxo-, Monosodium Salt

50. As-82071

51. Smr000058841

52. Sodium (2s-(2alpha,5alpha,6beta))-3,3-dimethyl-6-(((5-methyl-3-phenylisoxazol-4-yl)carbonyl)amino)-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate

53. Anhydrous Oxacillin Sodium [mart.]

54. Cas-1173-88-2

55. O0353

56. D97506

57. W-108566

58. Q27123265

59. Oxacillin Sodium, Antibiotic For Culture Media Use Only

60. Sodium 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanate

61. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, Sodium Salt (1:1), (2s,5r,6r)-

62. Sodium 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 423.4 g/mol
Molecular Formula C19H18N3NaO5S
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass423.08648614 g/mol
Monoisotopic Mass423.08648614 g/mol
Topological Polar Surface Area141 Ų
Heavy Atom Count29
Formal Charge0
Complexity687
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameBactocill in plastic container
Drug LabelOxacillin for Injection, USP is a semisynthetic penicillin antibiotic derived from the penicillin nucleus, 6-amino-penicillanic acid. It is resistant to inactivation by the enzyme penicillinase (beta-lactamase). It is the sodium salt in parenteral do...
Active IngredientOxacillin sodium
Dosage FormInjectable
RouteInjection
Strengtheq 20mg base/ml; eq 40mg base/ml
Market StatusPrescription
CompanyBaxter Hlthcare

2 of 4  
Drug NameOxacillin sodium
Active IngredientOxacillin sodium
Dosage FormInjectable
RouteInjection
Strengtheq 2gm base/vial; eq 10gm base/vial; eq 1gm base/vial
Market StatusPrescription
CompanyAurobindo Pharma; Sandoz; Sagent Pharms; Agila Speclts

3 of 4  
Drug NameBactocill in plastic container
Drug LabelOxacillin for Injection, USP is a semisynthetic penicillin antibiotic derived from the penicillin nucleus, 6-amino-penicillanic acid. It is resistant to inactivation by the enzyme penicillinase (beta-lactamase). It is the sodium salt in parenteral do...
Active IngredientOxacillin sodium
Dosage FormInjectable
RouteInjection
Strengtheq 20mg base/ml; eq 40mg base/ml
Market StatusPrescription
CompanyBaxter Hlthcare

4 of 4  
Drug NameOxacillin sodium
Active IngredientOxacillin sodium
Dosage FormInjectable
RouteInjection
Strengtheq 2gm base/vial; eq 10gm base/vial; eq 1gm base/vial
Market StatusPrescription
CompanyAurobindo Pharma; Sandoz; Sagent Pharms; Agila Speclts

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Penicillins [CS]; Penicillin-class Antibacterial [EPC]

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ABOUT THIS PAGE

Looking for 1173-88-2 / Oxacillin Sodium API manufacturers, exporters & distributors?

Oxacillin Sodium manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Oxacillin Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oxacillin Sodium manufacturer or Oxacillin Sodium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Oxacillin Sodium manufacturer or Oxacillin Sodium supplier.

PharmaCompass also assists you with knowing the Oxacillin Sodium API Price utilized in the formulation of products. Oxacillin Sodium API Price is not always fixed or binding as the Oxacillin Sodium Price is obtained through a variety of data sources. The Oxacillin Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Oxacillin Sodium

Synonyms

Oxacillin sodium salt, 1173-88-2, Oxabel, Prostaphlin, Bactocill, Sodium oxacillin

Cas Number

1173-88-2

Unique Ingredient Identifier (UNII)

4TWD2995UP

About Oxacillin Sodium

An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.

Oxacillin, Sodium Manufacturers

A Oxacillin, Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxacillin, Sodium, including repackagers and relabelers. The FDA regulates Oxacillin, Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxacillin, Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Oxacillin, Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Oxacillin, Sodium Suppliers

A Oxacillin, Sodium supplier is an individual or a company that provides Oxacillin, Sodium active pharmaceutical ingredient (API) or Oxacillin, Sodium finished formulations upon request. The Oxacillin, Sodium suppliers may include Oxacillin, Sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Oxacillin, Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Oxacillin, Sodium USDMF

A Oxacillin, Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Oxacillin, Sodium active pharmaceutical ingredient (API) in detail. Different forms of Oxacillin, Sodium DMFs exist exist since differing nations have different regulations, such as Oxacillin, Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Oxacillin, Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Oxacillin, Sodium USDMF includes data on Oxacillin, Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Oxacillin, Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Oxacillin, Sodium suppliers with USDMF on PharmaCompass.

Oxacillin, Sodium CEP

A Oxacillin, Sodium CEP of the European Pharmacopoeia monograph is often referred to as a Oxacillin, Sodium Certificate of Suitability (COS). The purpose of a Oxacillin, Sodium CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Oxacillin, Sodium EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Oxacillin, Sodium to their clients by showing that a Oxacillin, Sodium CEP has been issued for it. The manufacturer submits a Oxacillin, Sodium CEP (COS) as part of the market authorization procedure, and it takes on the role of a Oxacillin, Sodium CEP holder for the record. Additionally, the data presented in the Oxacillin, Sodium CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Oxacillin, Sodium DMF.

A Oxacillin, Sodium CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Oxacillin, Sodium CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Oxacillin, Sodium suppliers with CEP (COS) on PharmaCompass.

Oxacillin, Sodium WC

A Oxacillin, Sodium written confirmation (Oxacillin, Sodium WC) is an official document issued by a regulatory agency to a Oxacillin, Sodium manufacturer, verifying that the manufacturing facility of a Oxacillin, Sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Oxacillin, Sodium APIs or Oxacillin, Sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Oxacillin, Sodium WC (written confirmation) as part of the regulatory process.

click here to find a list of Oxacillin, Sodium suppliers with Written Confirmation (WC) on PharmaCompass.

Oxacillin, Sodium NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Oxacillin, Sodium as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Oxacillin, Sodium API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Oxacillin, Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Oxacillin, Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Oxacillin, Sodium NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Oxacillin, Sodium suppliers with NDC on PharmaCompass.

Oxacillin, Sodium GMP

Oxacillin, Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oxacillin, Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxacillin, Sodium GMP manufacturer or Oxacillin, Sodium GMP API supplier for your needs.

Oxacillin, Sodium CoA

A Oxacillin, Sodium CoA (Certificate of Analysis) is a formal document that attests to Oxacillin, Sodium's compliance with Oxacillin, Sodium specifications and serves as a tool for batch-level quality control.

Oxacillin, Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Oxacillin, Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oxacillin, Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxacillin, Sodium EP), Oxacillin, Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxacillin, Sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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