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Chemistry

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Also known as: 468-61-1, 2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate, Oxelaidin citrate, 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate, Snc1080t5y, 2-ethyl-2-phenylbutyric acid 2-(2-diethylaminoethoxy)ethyl ester
Molecular Formula
C20H33NO3
Molecular Weight
335.5  g/mol
InChI Key
IQADUMSPOQKAAO-UHFFFAOYSA-N
FDA UNII
SNC1080T5Y

Oxeladin
Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.
1 2D Structure

Oxeladin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate
2.1.2 InChI
InChI=1S/C20H33NO3/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4/h9-13H,5-8,14-17H2,1-4H3
2.1.3 InChI Key
IQADUMSPOQKAAO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCC(CC)(C1=CC=CC=C1)C(=O)OCCOCCN(CC)CC
2.2 Other Identifiers
2.2.1 UNII
SNC1080T5Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate

2. Oxeladin Citrate

3. Paxladine

4. Pectamol

5. Tussimol

2.3.2 Depositor-Supplied Synonyms

1. 468-61-1

2. 2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate

3. Oxelaidin Citrate

4. 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate

5. Snc1080t5y

6. 2-ethyl-2-phenylbutyric Acid 2-(2-diethylaminoethoxy)ethyl Ester

7. Ethanol, 2-(2-(diethylamino)ethoxy)-, 2-ethyl-2-phenylbutyrate

8. Oxeladin (inn)

9. Oxeladina [inn-spanish]

10. Oxeladin [inn]

11. Butyric Acid, 2-ethyl-2-phenyl-, 2-(2-(diethylamino)ethoxy)ethyl Ester

12. Oxeladine [inn-french]

13. Oxeladinum [inn-latin]

14. Oxeladinum

15. Oxeladina

16. Oxeladine

17. Oxeladin [inn:ban:dcf]

18. Einecs 207-412-1

19. Brn 2003403

20. Unii-snc1080t5y

21. Oxelaidin

22. Oxeladin Tannate

23. Pectamol (salt/mix)

24. Oxeladin [mi]

25. Oxeladin [who-dd]

26. Alpha,alpha-diethylbenzeneacetic Acid 2-(2-(diethylamino)ethoxy)ethyl Ester

27. Ec 207-412-1

28. 4-09-00-01906 (beilstein Handbook Reference)

29. Mls001047519

30. Schembl405413

31. Chembl1500276

32. Dtxsid0048343

33. Chebi:135424

34. Hms2800d17

35. Hms3604m03

36. Zinc3874580

37. Stl059065

38. Akos005711563

39. Db04822

40. Benzeneacetic Acid, .alpha.,.alpha.-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl Ester

41. Ncgc00389219-01

42. Ncgc00389219-02

43. Smr000425406

44. Sbi-0207046.p001

45. D08310

46. Ab00658553_05

47. Ab00658553_06

48. Q4332778

49. 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate #

50. 2-(2-diethylaminoethoxy)-ethyl 2-ethyl-2-phenylbutyrate

51. 2-(2-diethylaminoethoxy)ethyl .alpha.,.alpha.-diethylphenylacetate

52. .alpha.,.alpha.-diethylbenzeneacetic Acid 2-(2-(diethylamino)ethoxy)ethyl Ester

53. 2-ethyl-2-phenyl-butyric Acid 2-(2-diethylamino-ethoxy)-ethyl Ester; Compound With 3-carboxy-3-hydroxy-pentanedioic Acid

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 335.5 g/mol
Molecular Formula C20H33NO3
XLogP34
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count13
Exact Mass335.24604391 g/mol
Monoisotopic Mass335.24604391 g/mol
Topological Polar Surface Area38.8 Ų
Heavy Atom Count24
Formal Charge0
Complexity332
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antitussive Agents

Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. (See all compounds classified as Antitussive Agents.)


4.2 ATC Code

R - Respiratory system

R05 - Cough and cold preparations

R05D - Cough suppressants, excl. combinations with expectorants

R05DB - Other cough suppressants

R05DB09 - Oxeladin


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ABOUT THIS PAGE

Oxeladin Manufacturers

A Oxeladin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxeladin, including repackagers and relabelers. The FDA regulates Oxeladin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxeladin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Oxeladin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Oxeladin Suppliers

A Oxeladin supplier is an individual or a company that provides Oxeladin active pharmaceutical ingredient (API) or Oxeladin finished formulations upon request. The Oxeladin suppliers may include Oxeladin API manufacturers, exporters, distributors and traders.

click here to find a list of Oxeladin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Oxeladin GMP

Oxeladin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oxeladin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxeladin GMP manufacturer or Oxeladin GMP API supplier for your needs.

Oxeladin CoA

A Oxeladin CoA (Certificate of Analysis) is a formal document that attests to Oxeladin's compliance with Oxeladin specifications and serves as a tool for batch-level quality control.

Oxeladin CoA mostly includes findings from lab analyses of a specific batch. For each Oxeladin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oxeladin may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxeladin EP), Oxeladin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxeladin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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