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Chemistry

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Also known as: 28094-15-7, 6-hydroxydopamine hydrochloride, 5-(2-aminoethyl)benzene-1,2,4-triol hydrochloride, 6-hydroxydopamine chloride, Oxidopamine (hydrochloride), 2,4,5-trihydroxyphenethylamine hydrochloride
Molecular Formula
C8H12ClNO3
Molecular Weight
205.64  g/mol
InChI Key
QLMRJHFAGVFUAC-UHFFFAOYSA-N
FDA UNII
9WBV30HXTL

Oxidopamine Hydrobromide
A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
1 2D Structure

Oxidopamine Hydrobromide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride
2.1.2 InChI
InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
2.1.3 InChI Key
QLMRJHFAGVFUAC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=C(C(=CC(=C1O)O)O)CCN.Cl
2.2 Other Identifiers
2.2.1 UNII
9WBV30HXTL
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6 Hydroxydopamine

2. 6-hydroxydopamine

3. 6-ohda

4. Hydrobromide, Oxidopamine

5. Hydrochloride, Oxidopamine

6. Oxidopamine

7. Oxidopamine Hydrobromide

2.3.2 Depositor-Supplied Synonyms

1. 28094-15-7

2. 6-hydroxydopamine Hydrochloride

3. 5-(2-aminoethyl)benzene-1,2,4-triol Hydrochloride

4. 6-hydroxydopamine Chloride

5. Oxidopamine (hydrochloride)

6. 2,4,5-trihydroxyphenethylamine Hydrochloride

7. 6-hydroxydopamine Hcl

8. 9wbv30hxtl

9. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrochloride

10. 5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride

11. 6-hydroxydopamine Hydrochloride;6-ohda Hydrochloride

12. Nsc-233898

13. Ncgc00094747-01

14. Dsstox_cid_25838

15. Dsstox_rid_81164

16. Dsstox_gsid_45838

17. 2-(2,4,5-trihydroxyphenyl)ethan-1-aminium Chloride

18. Oxidopamine Hcl

19. Cas-28094-15-7

20. 2,5-dihydroxytyramine Hydrochloride

21. Einecs 248-837-2

22. Unii-9wbv30hxtl

23. Nsc 233898

24. 5-(2-aminoethyl)-1,2,4-benzenetriol Hydrochloride

25. 5-(2-aminoethyl)-4-hydroxypyrocatechol Hydrochloride

26. 6-hydroxy Dopamine Hydrochloride

27. 4-(2-aminoethyl)-1,2,3-benzenetriol Hydrochloride

28. 6-hydroxydopaminehydrochloride

29. Mfcd00012895

30. 1,2,3-benzenetriol, 4-(2-aminoethyl)-, Hydrochloride

31. 6-ohda Hydrochloride

32. 6-hd Hcl

33. Mls002207273

34. Schembl718426

35. Spectrum1500450

36. Chembl451197

37. Dtxsid0045838

38. Wln: Z2r Cq Dq Eq &gh

39. Hms1920d14

40. Pharmakon1600-01500450

41. Bcp18603

42. Hy-b1081

43. Tox21_111324

44. Ccg-40236

45. Nsc233898

46. Nsc757259

47. Akos015894730

48. Tox21_111324_1

49. Cs-4648

50. Nsc-757259

51. Ncgc00094747-02

52. Ncgc00167769-04

53. 3,5-trihydroxyphenethylamine Hydrochloride

54. As-60772

55. Smr001306794

56. Db-047336

57. Ft-0638757

58. D87854

59. 4-(2-aminoethyl)-1,3-benzenetriol Hydrochloride

60. A876787

61. 6-ohda Hydrochloride6-hydroxydopamine Hydrochloride

62. J-016968

63. 1,3-benzenetriol, 4-(2-aminoethyl)-, Hydrochloride

64. 1,4-benzenetriol, 5-(2-aminoethyl)-, Hydrochloride

65. 6-hydroxydopamine Hydrochloride; 6-ohda Hydrochloride

66. Q27273318

67. 1,2,4-benzenetriol,5-(2-aminoethyl)-,hydrochloride(1:1)

68. 6-hydroxydopamine Hydrochloride, >=97% (titration), Powder

69. 1,2,4-benzenetriol,5-(2-aminoethyl)-, Hydrochloride (1:1)

70. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrochloride (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 205.64 g/mol
Molecular Formula C8H12ClNO3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass205.0505709 g/mol
Monoisotopic Mass205.0505709 g/mol
Topological Polar Surface Area86.7 Ų
Heavy Atom Count13
Formal Charge0
Complexity142
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Sympatholytics

Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)


Adrenergic Agents

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)


ABOUT THIS PAGE

Oxidopamine Hydrobromide Manufacturers

A Oxidopamine Hydrobromide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxidopamine Hydrobromide, including repackagers and relabelers. The FDA regulates Oxidopamine Hydrobromide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxidopamine Hydrobromide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Oxidopamine Hydrobromide Suppliers

A Oxidopamine Hydrobromide supplier is an individual or a company that provides Oxidopamine Hydrobromide active pharmaceutical ingredient (API) or Oxidopamine Hydrobromide finished formulations upon request. The Oxidopamine Hydrobromide suppliers may include Oxidopamine Hydrobromide API manufacturers, exporters, distributors and traders.

click here to find a list of Oxidopamine Hydrobromide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Oxidopamine Hydrobromide USDMF

A Oxidopamine Hydrobromide DMF (Drug Master File) is a document detailing the whole manufacturing process of Oxidopamine Hydrobromide active pharmaceutical ingredient (API) in detail. Different forms of Oxidopamine Hydrobromide DMFs exist exist since differing nations have different regulations, such as Oxidopamine Hydrobromide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Oxidopamine Hydrobromide DMF submitted to regulatory agencies in the US is known as a USDMF. Oxidopamine Hydrobromide USDMF includes data on Oxidopamine Hydrobromide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Oxidopamine Hydrobromide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Oxidopamine Hydrobromide suppliers with USDMF on PharmaCompass.

Oxidopamine Hydrobromide GMP

Oxidopamine Hydrobromide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oxidopamine Hydrobromide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxidopamine Hydrobromide GMP manufacturer or Oxidopamine Hydrobromide GMP API supplier for your needs.

Oxidopamine Hydrobromide CoA

A Oxidopamine Hydrobromide CoA (Certificate of Analysis) is a formal document that attests to Oxidopamine Hydrobromide's compliance with Oxidopamine Hydrobromide specifications and serves as a tool for batch-level quality control.

Oxidopamine Hydrobromide CoA mostly includes findings from lab analyses of a specific batch. For each Oxidopamine Hydrobromide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oxidopamine Hydrobromide may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxidopamine Hydrobromide EP), Oxidopamine Hydrobromide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxidopamine Hydrobromide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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