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Chemistry

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Also known as: 959-14-8, N,n-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine, Oxolamina, Oksalamin, 683 m, Af 438
Molecular Formula
C14H19N3O
Molecular Weight
245.32  g/mol
InChI Key
IDCHQQSVJAAUQQ-UHFFFAOYSA-N
FDA UNII
90BEA145GY

Oxolamine Citrate
Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant. It is listed as a prescription drug in New Zealand legislation. Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation.
1 2D Structure

Oxolamine Citrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine
2.1.2 InChI
InChI=1S/C14H19N3O/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3
2.1.3 InChI Key
IDCHQQSVJAAUQQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCN(CC)CCC1=NC(=NO1)C2=CC=CC=C2
2.2 Other Identifiers
2.2.1 UNII
90BEA145GY
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5-diethylaminoethyl-3-phenyl-1,2,4-oxadiazole

2. Bredon

3. Oxobron

4. Oxolamine Citrate

5. Oxolamine Monohydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 959-14-8

2. N,n-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine

3. Oxolamina

4. Oksalamin

5. 683 M

6. Af 438

7. Oxadiazole; 683m

8. 5-(2-diethylaminoethyl)-3-phenyl-1,2,4-oxadiazole

9. Af-438 Free Base

10. N,n-diethyl-3-phenyl-1,2,4-oxadiazole-5-ethanamine

11. 90bea145gy

12. Skf 9976 Free Base

13. Skf-9976 Free Base

14. Af-438 [as Citrate]

15. Oxolamine (inn)

16. Skf 9976 [as Citrate]

17. 5-(2-dietilaminoetil)-3-fenil-1,2,4-oxadiazolo

18. Oxolamine [inn]

19. Oxolev

20. Jatan

21. 1,2,4-oxadiazole, 5-(2-(diethylamino)ethyl)-3-phenyl-

22. Oxolev A

23. Ossolamina [dcit]

24. Oxolamina [italian]

25. Ossolamina

26. Oxolaminum

27. Oxolamine [inn:dcf]

28. N,n-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethan-1-amine

29. Oxolaminum [inn-latin]

30. Oxolamina [inn-spanish]

31. Einecs 213-493-4

32. Brn 0527181

33. Unii-90bea145gy

34. Oksalamin (tn)

35. 3-phenyl-5-(beta-diethylaminoethyl)-1,2,4-oxodiazole

36. 5-(2-dietilaminoetil)-3-fenil-1,2,4-oxadiazolo [italian]

37. Oxolamine [mi]

38. Prestwick0_000826

39. Prestwick1_000826

40. Prestwick2_000826

41. Prestwick3_000826

42. Oxolamine [mart.]

43. Ec 213-493-4

44. Oxolamine [who-dd]

45. Bspbio_000751

46. Schembl893333

47. Spbio_002672

48. Bpbio1_000827

49. Zinc1874

50. 1,2,4-oxadiazole-5-ethanamine, N,n-diethyl-3-phenyl-

51. Chembl1620875

52. Dtxsid5023403

53. Chebi:94607

54. Db13216

55. Ncgc00179449-01

56. Sbi-0207016.p001

57. Ft-0748644

58. D07387

59. 959o148

60. Q576684

61. Brd-k42596464-048-03-6

62. 3-phenyl-5-(.beta.-diethylaminoethyl)-1,2,4-oxodiazole

63. N,n-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine 2-hydroxy-1,2,3-propanetricarboxylate

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 245.32 g/mol
Molecular Formula C14H19N3O
XLogP32.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass245.152812238 g/mol
Monoisotopic Mass245.152812238 g/mol
Topological Polar Surface Area42.2 Ų
Heavy Atom Count18
Formal Charge0
Complexity227
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antitussive Agents

Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. (See all compounds classified as Antitussive Agents.)


4.2 ATC Code

R - Respiratory system

R05 - Cough and cold preparations

R05D - Cough suppressants, excl. combinations with expectorants

R05DB - Other cough suppressants

R05DB07 - Oxolamine


API SUPPLIERS

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01

Gonane Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Virtual BoothGonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

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Gonane Pharma

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Cohance Lifesciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

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Nishchem International Pvt. Ltd

India

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Rumit Group of Companies

India

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CHORUS LABS LIMITED

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Refarmed Chemicals

Switzerland

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Refarmed Chemicals

Switzerland

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Shanvr Life Sciences

India

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Angelini Pharma

Italy

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Angelini Pharma

Italy

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API Reference Price

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11-Jan-2021
26-Nov-2024
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ABOUT THIS PAGE

Oxolamine Citrate Manufacturers

A Oxolamine Citrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxolamine Citrate, including repackagers and relabelers. The FDA regulates Oxolamine Citrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxolamine Citrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Oxolamine Citrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Oxolamine Citrate Suppliers

A Oxolamine Citrate supplier is an individual or a company that provides Oxolamine Citrate active pharmaceutical ingredient (API) or Oxolamine Citrate finished formulations upon request. The Oxolamine Citrate suppliers may include Oxolamine Citrate API manufacturers, exporters, distributors and traders.

click here to find a list of Oxolamine Citrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Oxolamine Citrate WC

A Oxolamine Citrate written confirmation (Oxolamine Citrate WC) is an official document issued by a regulatory agency to a Oxolamine Citrate manufacturer, verifying that the manufacturing facility of a Oxolamine Citrate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Oxolamine Citrate APIs or Oxolamine Citrate finished pharmaceutical products to another nation, regulatory agencies frequently require a Oxolamine Citrate WC (written confirmation) as part of the regulatory process.

click here to find a list of Oxolamine Citrate suppliers with Written Confirmation (WC) on PharmaCompass.

Oxolamine Citrate GMP

Oxolamine Citrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oxolamine Citrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxolamine Citrate GMP manufacturer or Oxolamine Citrate GMP API supplier for your needs.

Oxolamine Citrate CoA

A Oxolamine Citrate CoA (Certificate of Analysis) is a formal document that attests to Oxolamine Citrate's compliance with Oxolamine Citrate specifications and serves as a tool for batch-level quality control.

Oxolamine Citrate CoA mostly includes findings from lab analyses of a specific batch. For each Oxolamine Citrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oxolamine Citrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxolamine Citrate EP), Oxolamine Citrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxolamine Citrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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