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    Chemistry

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    Also known as: 2277-92-1, Zanil, Zanilox, Oxiclozanidum, Oxyclozanid, Diplin
    Molecular Formula
    C13H6Cl5NO3
    Molecular Weight
    401.4  g/mol
    InChI Key
    JYWIYHUXVMAGLG-UHFFFAOYSA-N
    FDA UNII
    1QS9G4876X
    Oxyclozanide
    Anthelmintic used in grazing animals for fasciola and cestode infestations.
    1 2D Structure

    Oxyclozanide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
    2.1.2 InChI
    InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
    2.1.3 InChI Key
    JYWIYHUXVMAGLG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=C(C=C(C(=C1NC(=O)C2=C(C(=CC(=C2Cl)Cl)Cl)O)O)Cl)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    1QS9G4876X
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Oxiclozanidum

    2. Zanil

    2.3.2 Depositor-Supplied Synonyms

    1. 2277-92-1

    2. Zanil

    3. Zanilox

    4. Oxiclozanidum

    5. Oxyclozanid

    6. Diplin

    7. 2,3,5-trichloro-n-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide

    8. Benzamide, 2,3,5-trichloro-n-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-

    9. 3,3',5,5',6-pentachloro-2'-hydroxysalicylanilide

    10. Ici 46683

    11. 1qs9g4876x

    12. Ici-46683

    13. Oxyclozanide (inn)

    14. Oxyclozanide [inn]

    15. Oxiclozanida

    16. Oxyclozanidum

    17. Oxyclozanide [inn:ban]

    18. Oxyclozanidum [inn-latin]

    19. Oxiclozanida [inn-spanish]

    20. Ccris 5744

    21. Einecs 218-904-0

    22. Ici 46638

    23. Brn 2014120

    24. Unii-1qs9g4876x

    25. 2,2'-dihydroxy-3,3',5,5',6-pentachlorobenzanilide

    26. 3,3',5,5',6-pentachloro-2,2'-dihydroxybenzanilide

    27. 3,5,6,3',5'-pentachloro-2,2'-dihydroxybenzanilide

    28. Salicylanilide, 3,3',5,5',6-pentachloro-2'-hydroxy-

    29. Oxyclozanide [mi]

    30. Zanil [veterinay] (tn)

    31. Oxyclozanide [mart.]

    32. Mls006010020

    33. Oxyclozanide [who-dd]

    34. Schembl166224

    35. Chembl2105450

    36. Benzanilide, 2,2'-dihydroxy-3,3',5,5',6-pentachloro-

    37. Dtxsid50177312

    38. Zinc2038733

    39. Mfcd00864507

    40. S5017

    41. Akos015889853

    42. Ccg-268664

    43. Cs-3973

    44. As-12188

    45. Hy-17594

    46. Smr004701204

    47. Ft-0603601

    48. A16979

    49. C74174

    50. D08320

    51. Oxyclozanide, Vetranal(tm), Analytical Standard

    52. 277o921

    53. A816351

    54. Sr-01000944913

    55. J-014851

    56. Q7115903

    57. Sr-01000944913-1

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 401.4 g/mol
    Molecular Formula C13H6Cl5NO3
    XLogP35.7
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count2
    Exact Mass400.876081 g/mol
    Monoisotopic Mass398.879032 g/mol
    Topological Polar Surface Area69.6 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity415
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antiplatyhelmintic Agents

    Agents used to treat cestode, trematode, or other flatworm infestations in man or animals. (See all compounds classified as Antiplatyhelmintic Agents.)

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    04-Jan-2021
    31-Aug-2024
    KGS
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