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Oxyfedrine Hydrochloride

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ACTIVE PHARMA INGREDIENTS

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INTERMEDIATES

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Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

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CEP/COS

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API REF. PRICE (USD/KG)

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Chemistry

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Also known as: 16777-42-7, Oxyfedrine hcl, Ildamen, Modacor, L-oxyfedrine hydrochloride, Oxyfedrine l-form hydrochloride

Molecular Formula

C₁₉H₂₄ClNO₃

Molecular Weight

349.8 g/mol

InChI Key

JMUPNNYLJGSMPK-JPJJPTBZSA-N

FDA UNII

63CF9XK7DA

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

1 2D Structure

Oxyfedrine Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride

2.1.2 InChI

InChI=1S/C19H23NO3.ClH/c1-14(19(22)15-7-4-3-5-8-15)20-12-11-18(21)16-9-6-10-17(13-16)23-2;/h3-10,13-14,19-20,22H,11-12H2,1-2H3;1H/t14-,19-;/m0./s1

2.1.3 InChI Key

JMUPNNYLJGSMPK-JPJJPTBZSA-N

2.1.4 Canonical SMILES

CC(C(C1=CC=CC=C1)O)NCCC(=O)C2=CC(=CC=C2)OC.Cl

2.1.5 Isomeric SMILES

C[C@@H]([C@@H](C1=CC=CC=C1)O)NCCC(=O)C2=CC(=CC=C2)OC.Cl

2.2 Other Identifiers

2.2.1 UNII

63CF9XK7DA

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Ildamen

2. Myofedrin

3. Oxifedrine

4. Oxiphedrin

5. Oxyfedrine

6. Oxyphedrin

2.3.2 Depositor-Supplied Synonyms

1. 16777-42-7

2. Oxyfedrine Hcl

3. Ildamen

4. Modacor

5. L-oxyfedrine Hydrochloride

6. Oxyfedrine L-form Hydrochloride

7. Oxyfedrine Hydrochloride, Dl-

8. 63cf9xk7da

9. H1cac99b4d

10. 14223-94-0

11. Oxyfedrine L-form Hcl

12. Oxyfedrin

13. Dsstox_cid_28558

14. Dsstox_rid_82830

15. Dsstox_gsid_48632

16. 3-[[(1r,2s)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one;hydrochloride

17. Oxyfedrine Hydrochloride (jan)

18. Oxyfedrine Hydrochloride [jan]

19. Myophedrine

20. D,l-oxyphedrine

21. 1-propanone, 3-[[(1s,2r)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-, Hydrochloride (1:1)

22. Cas-16777-42-7

23. Dl-oxyfedrine Hydrochloride

24. Fda 1576

25. Ncgc00182060-02

26. Einecs 240-828-1

27. Unii-h1cac99b4d

28. Oxyfedrine Dl-form Hydrochloride

29. D563

30. D 563

31. Propiophenone, 3-((beta-hydroxy-alpha-methylphenethyl)amino)-3'-methoxy-, Hydrochloride, D,l-

32. 1-propanone, 3-(((1s,2r)-2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, Hydrochloride (1:1)

33. Ildamen (tn)

34. Unii-63cf9xk7da

35. L-3-methoxy-omega-(1-hydroxy-1-phenylisopropylamino)propiophenone Hydrochloride

36. 1-propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, Hcl, L-

37. L-(1-hydroxy-1-phenyl-2-propylamino)-1-(m-methoxyphenyl)-1-propanone Hydrochloride

38. L-3-(beta-hydroxy-alpha-methyl-phenethylamino)-3'-methoxypropiophenone, Hydrochloride

39. Schembl209076

40. Chembl2354521

41. Dtxsid0048632

42. Fda-1576

43. Tox21_112976

44. Akos037653995

45. Tox21_112976_1

46. Ks-1460

47. 1-propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, Hcl, D,l-

48. D,l-3-(beta-hydroxy-alpha-methyl-phenethylamino)-3'-methoxypropiophenone, Hydrochloride

49. Oxyfedrine Hydrochloride [mart.]

50. Oxyfedrine Hydrochloride, (-)-

51. Propiophenone, 3-((beta-hydroxy-alpha-methylphenethyl)amino)-3'-methoxy-, Hydrochloride, (-)-

52. Ncgc00182060-03

53. Oxyfedrine Hydrochloride [who-dd]

54. (r*,s*)-(+-)-3-((2-hydroxy-1-methyl-2-phenethyl)amino)-1-(3-methoxyphenyl)-1-propanone Hydrochloride

55. (r-(r*,s*))-3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-3'-methoxypropiophenone Hydrochloride

56. 1-propanone, 3-((2-hydroxy-1-methyl-2-phenethyl)amino)-1-(3-methoxyphenyl)-, Hcl, (r*,s*)-

57. D-563

58. Oxyfedrine Dl-form Hydrochloride [mi]

59. Oxyfedrine L-form Hydrochloride [mi]

60. D01233

61. A810903

62. 1-(3-methoxyphenyl)-3-[[(1r,2s)-1-oxidanyl-1-phenyl-propan-2-yl]amino]propan-1-one Hydrochloride

63. 1-propanone, 3-(((1r,2s)-2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, Hydrochloride (1:1), Rel-

64. 1-propanone, 3-((2-hydroxy-1-methyl-2-phenethyl)amino)-1-(3-methoxyphenyl)-, Hydrochloride, (r*,s*)-(+-)-

65. 3-(((.alpha.s,.beta.r)-.beta.-hydroxy-.alpha.-methylphenethyl)amino)-3'-methoxypropiophenone Hydrochloride

66. 3-((1r,2s)-1-hydroxy-1-phenylpropan-2-ylamino)-1-(3-methoxyphenyl)propan-1-one Hydrochloride

67. 3-[[(1r,2s)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)-1-propanone Hydrochloride

68. Propiophenone, 3-((.beta.-hydroxy-.alpha.-methylphenethyl)amino)-3'-methoxy-, Hydrochloride, (-)-

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₄ClNO₃
Molecular Weight	349.8 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	8
Exact Mass	349.1444713 g/mol
Monoisotopic Mass	349.1444713 g/mol
Topological Polar Surface Area	58.6 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	355
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Adrenergic beta-Agonists

Drugs that selectively bind to and activate beta-adrenergic receptors. (See all compounds classified as Adrenergic beta-Agonists.)

Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

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ABOUT THIS PAGE

Oxyfedrine Hydrochloride Manufacturers

A Oxyfedrine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxyfedrine Hydrochloride, including repackagers and relabelers. The FDA regulates Oxyfedrine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxyfedrine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Oxyfedrine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Oxyfedrine Hydrochloride Suppliers

A Oxyfedrine Hydrochloride supplier is an individual or a company that provides Oxyfedrine Hydrochloride active pharmaceutical ingredient (API) or Oxyfedrine Hydrochloride finished formulations upon request. The Oxyfedrine Hydrochloride suppliers may include Oxyfedrine Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Oxyfedrine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Oxyfedrine Hydrochloride GMP

Oxyfedrine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oxyfedrine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxyfedrine Hydrochloride GMP manufacturer or Oxyfedrine Hydrochloride GMP API supplier for your needs.

Oxyfedrine Hydrochloride CoA

A Oxyfedrine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Oxyfedrine Hydrochloride's compliance with Oxyfedrine Hydrochloride specifications and serves as a tool for batch-level quality control.

Oxyfedrine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Oxyfedrine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oxyfedrine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxyfedrine Hydrochloride EP), Oxyfedrine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxyfedrine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.