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1. 8 Hydroxyquinoline
2. 8 Hydroxyquinoline Sulfate
3. 8 Oxyquinoline
4. 8 Quinolinol
5. 8-hydroxyquinoline Sulfate
6. 8-oxyquinoline
7. 8-quinolinol
8. Bioquin
9. Chinosol
10. Khinozol
11. Leioderm
12. Oxine
13. Oxyquinol
14. Oxyquinoline
15. Oxyquinoline Potassium Sulfate (2:1)
16. Oxyquinoline Sulfate
17. Quinosol
18. Sulfate, 8-hydroxyquinoline
19. Sulfate, Oxyquinoline
20. Superol
1. Quinolin-8-ol
2. 8-quinolinol
3. 148-24-3
4. Oxyquinoline
5. Oxine
6. Quinophenol
7. Oxychinolin
8. 8-quinol
9. 8-oxyquinoline
10. Phenopyridine
11. 8-hydroxychinolin
12. Bioquin
13. Oxybenzopyridine
14. Hydroxybenzopyridine
15. Oxin
16. 1-azanaphthalene-8-ol
17. Tumex
18. 8-chinolinol
19. 8-oq
20. 8-hydroxy-chinolin
21. Fennosan H 30
22. 8-oxychinolin
23. Fennosan
24. Oxyquinol
25. O-oxychinolin
26. Usaf Ek-794
27. Hydroxyquinoline
28. Oxyquinoline [usan]
29. 8-hydroxy-quinoline
30. Nci-c55298
31. Nsc 2039
32. Mfcd00006807
33. Oxoquinoline
34. Albisal
35. Nsc 615011
36. Nsc-2039
37. Nsc285166
38. 8-quinolinol, Homopolymer
39. Nsc-285166
40. Nsc-402623
41. Nsc-615011
42. Mls002702126
43. 5utx5635hp
44. Chembl310555
45. Chebi:48981
46. Nsc 82408
47. Quinoline-8-ol
48. Oxyquinoline (8-hydroxyquinoline)
49. Nsc 82404
50. Nsc-48037
51. Nsc-54230
52. Nsc-82404
53. Nsc-82405
54. Nsc-82409
55. Nsc-82410
56. Nsc-82412
57. Nsc615011
58. J2.960b
59. Oxyquinoline (usan)
60. Ncgc00090708-03
61. Ncgc00090708-05
62. Dsstox_cid_730
63. Dsstox_rid_75758
64. Wln: T66 Bnj Jq
65. Dsstox_gsid_20730
66. Oxine;8-hydroxyquinoline;quinophenol;8-quinolinone
67. Fennosan Hf-15
68. Caswell No. 719
69. 8-chinolinol [czech]
70. O-oxychinolin [german]
71. Quinoline, 8-hydroxy-
72. 84063-18-3
73. Cas-148-24-3
74. Manganese, Bis(8-quinolinolato)-
75. Smr000112313
76. 8-hydroxy-chinolin [german]
77. Ccris 340
78. 8-hydroxy Quinoline
79. Hsdb 4073
80. Einecs 205-711-1
81. Epa Pesticide Chemical Code 059803
82. Brn 0114512
83. Unii-5utx5635hp
84. Oxychinoline
85. Ai3-00483
86. 8-oxyquinolin
87. 8-quinolinone
88. 8-quinolol
89. 8-hydroxiquinoline
90. 8-hydroxychinoline
91. 8-hydroxylquinoline
92. Hqy
93. 8-quinolinol, P.a.
94. Spectrum_001053
95. 3vh9
96. 8-hydroxyquinoline Oxine
97. Spectrum2_000697
98. Spectrum3_000534
99. Spectrum4_000465
100. Spectrum5_001280
101. Oxyquinoline [ii]
102. 8-hydroxyquinoline, 99%
103. Ec 205-711-1
104. Ncimech_000694
105. Oxyquinoline [hsdb]
106. Oxyquinoline [inci]
107. Cid_1923
108. Ncistruc1_000152
109. Ncistruc2_000240
110. Oxyquinol Reference Spectrum
111. Nciopen2_000962
112. Nciopen2_001020
113. Nciopen2_001220
114. Nciopen2_004264
115. Oxyquinoline [vandf]
116. Schembl37189
117. Bspbio_002147
118. Kbiogr_000910
119. Kbioss_001533
120. 5-21-03-00252 (beilstein Handbook Reference)
121. Mls001055492
122. Bidd:er0371
123. Divk1c_000757
124. Spbio_000853
125. 8-hydroxyquinoline, Crystalline
126. Zinc8492
127. Hydroxyquinoline [vandf]
128. 8-hydroxyquinoline [mi]
129. Dtxsid5020730
130. Bdbm32203
131. Hms502f19
132. Kbio1_000757
133. Kbio2_001533
134. Kbio2_004101
135. Kbio2_006669
136. Kbio3_001647
137. Hydroxyquinoline [who-dd]
138. Nsc2039
139. 8-hydroxyquinoline [iarc]
140. Ninds_000757
141. 8-quinolinol (7ci,8ci,9ci)
142. Act08881
143. Hy-b1005
144. Str00721
145. Tox21_113083
146. Tox21_202986
147. Tox21_400006
148. 8-oxychinolin, 8-quinolinol, Oxine
149. Ccg-35870
150. Nsc 48037
151. Nsc 54230
152. Nsc 82405
153. Nsc 82409
154. Nsc 82410
155. Nsc 82412
156. Nsc402623
157. S4547
158. Stk943764
159. 8-hydroxyquinoline Acs Reagent Grade
160. Akos001061311
161. Ac-5109
162. Cs-4502
163. Db11145
164. Nsc 285166
165. Nsc 402623
166. Ps-4553
167. Sb40773
168. 8-hydroxyquinoline, Acs Reagent, 99%
169. Idi1_000757
170. Ncgc00090708-01
171. Ncgc00090708-02
172. Ncgc00090708-04
173. Ncgc00090708-06
174. Ncgc00090708-07
175. Ncgc00090708-08
176. Ncgc00090708-11
177. Ncgc00260531-01
178. Nci60_001712
179. Nci60_002335
180. 8-hydroxyquinoline Acs Grade 100g
181. Sbi-0051472.p003
182. Db-012222
183. Am20050821
184. Ft-0621550
185. H0305
186. 8-quinolinol, Jis Special Grade, >=99.0%
187. 8-quinolinol, Vetec(tm) Reagent Grade, 99%
188. En300-17403
189. C19434
190. D05321
191. P17615
192. Us9394254, 6
193. 8-quinolinol, Pestanal(r), Analytical Standard
194. Ab00052065_08
195. 8-quinolinol, >=99% (perchloric Acid Titration)
196. A808745
197. Ap-065/40180076
198. Q270162
199. Cu-01000012874-2
200. W-108106
201. Brd-k66808046-065-01-1
202. Z56926518
203. F0001-0526
204. 8-quinolinol, Puriss. P.a., Acs Reagent, For The Detection And Determination Of Al, Mg And Others, >=99.0% (nt)
205. 8-quinolinol, Puriss. P.a., Acs Reagent, Reag. Ph. Eur., >=99% (perchloric Acid Titration)
Molecular Weight | 145.16 g/mol |
---|---|
Molecular Formula | C9H7NO |
XLogP3 | 2 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 0 |
Exact Mass | 145.052763847 g/mol |
Monoisotopic Mass | 145.052763847 g/mol |
Topological Polar Surface Area | 33.1 Ų |
Heavy Atom Count | 11 |
Formal Charge | 0 |
Complexity | 138 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
A BACTERIOSTATIC & FUNGISTATIC COMPOUND; USED PRINCIPALLY IN TREATMENT OF MINOR BURNS & OF HEMORRHOIDS.
Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1111
OXYQUINOLINE SULFATE ... IS ... USED ... IN TREATMENT OF ATHLETE'S FOOT, VAGINITIS, & AS A GARGLE, EYEWASH, NASAL DOUCHE, & IN HEMORRHOIDAL PREPARATIONS ... /OXYQUINOLINE SULFATE/
Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1111
/OVER THE COUNTER/ HYDROXYQUINOLINE IS 1 OF 4 ANTIFUNGAL AGENTS RECOMMENDED FOR ACTIVE TREATMENT OF FUNGUS ASSOCIATED WITH DIAPER RASH & PRICKLY HEAT IN BABIES. /HYDROXYQUINOLINE/
SADIK F; J AM PHARM ASSOC NS10 (JAN): 19-24 (1970)
8-HYDROXYQUNIOLINE SULFATE INHIBITED FORMATION OF ARTIFICIAL CALCULUS IN VITRO & RAT CALCULUS IN VIVO. IN RATS, IT PREVENTED CALCULUS FORMATION WHEN APPLIED BY SWABBING OR BY INTRAORAL INSTILLATION. IN DOGS, FORMATION OF DENTAL PLAQUE WAS INHIBITED 33 TO 98% IN COMPARISON TO PLACEBO. ALSO, 25 TO 58% OF ESTABLISHED PLAQUE ACCUMULATIONS WERE REMOVED, WHEREAS PLACEBO REMOVED 2 TO 22%.
PMID:815301 DEPALMA PD ET AL; J DENT RES 55 (2): 292-8 (1976)
For more Therapeutic Uses (Complete) data for 8-HYDROXYQUINOLINE (7 total), please visit the HSDB record page.
Oxyquinoline is used as a biocidal component of several over the counter products. These products are marketed for the purposes of inhibiting abnormal biological growth in the vagina and restoring natural pH.
Oxyquinoline acts as a biocide to eliminate bacteria and fungi.
A - Alimentary tract and metabolism
A01 - Stomatological preparations
A01A - Stomatological preparations
A01AB - Antiinfectives and antiseptics for local oral treatment
A01AB07 - Oxyquinoline
D - Dermatologicals
D08 - Antiseptics and disinfectants
D08A - Antiseptics and disinfectants
D08AH - Quinoline derivatives
D08AH03 - Oxyquinoline
G - Genito urinary system and sex hormones
G01 - Gynecological antiinfectives and antiseptics
G01A - Antiinfectives and antiseptics, excl. combinations with corticosteroids
G01AC - Quinoline derivatives
G01AC30 - Oxyquinoline
R - Respiratory system
R02 - Throat preparations
R02A - Throat preparations
R02AA - Antiseptics
R02AA14 - Oxyquinoline
Route of Elimination
Oxyquinoline is excreted in both the primarily in the urine with some in the bile.
IN RATS /MALE, DONRYU STRAIN, IV INJECTION/ 8-HYDROXYQUINOLINE WAS METABOLIZED TO GLUCURONIDE & SULFATE CONJUGATES. MORE 8-HYDROXYQUINOLINE GLUCURONIDE WAS EXCRETED IN URINE THAN 8-HYDROXYQUINOLINE SULFATE CONJUGATE. ONLY THE GLUCURONIDE CONJUGATE WAS EXCRETED IN BILE.
PMID:409509 KIWADA H ET AL; CHEM PHARM BULL 25 (7): 1566-73 (1977)
8-HYDROXYQUINOLINE WAS METABOLIZED TO GLUCURONIDE & SULFATE CONJUGATES AFTER IV ADMIN IN RATS /MALE, DONRYU STRAIN/. THE GLUCURONIDES WERE EXCRETED IN BILE & URINE, BUT THE SULFATES WERE EXCRETED EXCLUSIVELY IN THE URINE. UNMETABOLIZED FORMS WERE ONLY SLIGHTLY EXCRETED.
PMID:96945 SAWADA Y ET AL; CHEM PHARM BULL 26 (5): 1357-63 (1978)
In the urine, 60% of the dose is excreted as glucuronide conjugates and 23% of the dose as sulfate conjugates. In the bile, 9% of the total dose is found as glucuronide conjugates.
IN RATS /MALE, DONRYU STRAIN, IV INJECTION/ 8-HYDROXYQUINOLINE WAS METABOLIZED TO GLUCURONIDE & SULFATE CONJUGATES.
PMID:409509 KIWADA H ET AL; CHEM PHARM BULL 25 (7): 1566-73 (1977)
8-HYDROXYQUINOLINE WAS METABOLIZED TO GLUCURONIDE & SULFATE CONJUGATES AFTER IV ADMIN IN RATS /MALE, DONRYU STRAIN/. UNMETABOLIZED FORMS WERE ONLY SLIGHTLY EXCRETED.
PMID:96945 SAWADA Y ET AL; CHEM PHARM BULL 26 (5): 1357-63 (1978)
The mechanism by which oxyquinoline exerts its biocidal effect is unknown.
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ABOUT THIS PAGE
A Oxyquinoline Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxyquinoline Sulfate, including repackagers and relabelers. The FDA regulates Oxyquinoline Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxyquinoline Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Oxyquinoline Sulfate supplier is an individual or a company that provides Oxyquinoline Sulfate active pharmaceutical ingredient (API) or Oxyquinoline Sulfate finished formulations upon request. The Oxyquinoline Sulfate suppliers may include Oxyquinoline Sulfate API manufacturers, exporters, distributors and traders.
click here to find a list of Oxyquinoline Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Oxyquinoline Sulfate DMF (Drug Master File) is a document detailing the whole manufacturing process of Oxyquinoline Sulfate active pharmaceutical ingredient (API) in detail. Different forms of Oxyquinoline Sulfate DMFs exist exist since differing nations have different regulations, such as Oxyquinoline Sulfate USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Oxyquinoline Sulfate DMF submitted to regulatory agencies in the US is known as a USDMF. Oxyquinoline Sulfate USDMF includes data on Oxyquinoline Sulfate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Oxyquinoline Sulfate USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Oxyquinoline Sulfate suppliers with USDMF on PharmaCompass.
A Oxyquinoline Sulfate written confirmation (Oxyquinoline Sulfate WC) is an official document issued by a regulatory agency to a Oxyquinoline Sulfate manufacturer, verifying that the manufacturing facility of a Oxyquinoline Sulfate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Oxyquinoline Sulfate APIs or Oxyquinoline Sulfate finished pharmaceutical products to another nation, regulatory agencies frequently require a Oxyquinoline Sulfate WC (written confirmation) as part of the regulatory process.
click here to find a list of Oxyquinoline Sulfate suppliers with Written Confirmation (WC) on PharmaCompass.
National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Oxyquinoline Sulfate as an active pharmaceutical ingredient (API).
The FDA updates the NDC directory daily. The NDC numbers for Oxyquinoline Sulfate API and other APIs are published in this directory by the FDA.
The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.
Pharmaceutical companies that manufacture Oxyquinoline Sulfate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.
The NDC directory also contains data on finished compounded human drug products that contain Oxyquinoline Sulfate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Oxyquinoline Sulfate NDC to their finished compounded human drug products, they may choose to do so.
click here to find a list of Oxyquinoline Sulfate suppliers with NDC on PharmaCompass.
Oxyquinoline Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Oxyquinoline Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxyquinoline Sulfate GMP manufacturer or Oxyquinoline Sulfate GMP API supplier for your needs.
A Oxyquinoline Sulfate CoA (Certificate of Analysis) is a formal document that attests to Oxyquinoline Sulfate's compliance with Oxyquinoline Sulfate specifications and serves as a tool for batch-level quality control.
Oxyquinoline Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Oxyquinoline Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Oxyquinoline Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxyquinoline Sulfate EP), Oxyquinoline Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxyquinoline Sulfate USP).
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