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Suanfarma Oxytetracycline Hydrochloride

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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xyz-pharma-m-2024-10-07

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Oxytetracycline Hydrochloride

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Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

32 API Suppliers, 13 USDMF, 13 CEP/COS, 3 JDMF, 1 EU WC, 8 NDC API, 13 VMF, 7 Listed Suppliers, $ API Reference Price

32 API Suppliers
13 USDMF
13 CEP/COS
3 JDMF
1 EU WC
8 NDC API
13 VMF
7 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

31 FDF Dossiers, 13 FDA Orange Book, 2 Europe, 9 Canada, 7 Listed Dossiers

31 FDF Dossiers
13 FDA Orange Book
2 Europe
9 Canada
7 Listed Dossiers

RELATED EXCIPIENT COMPANIES

4 SPI Pharma, 2 Seqens, 2 DKSH, 2 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 6 Actylis, 1 Aeon Procare, 1 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 9 BASF, 1 Finar, 6 Gangwal Chemicals, 1 Kerry, 1 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 1 Pluviaendo, 1 Roquette, 6 Seppic, 1 Sigachi Industries

EXCIPIENTS BY APPLICATIONS

14 Solubilizers, 10 Parenteral, 10 Topical, 9 Thickeners and Stabilizers, 8 Direct Compression, 6 Fillers, Diluents & Binders, 5 Taste Masking, 5 Controlled & Modified Release, 5 Emulsifying Agents, 4 Co-Processed Excipients, 3 Chewable & Orodispersible Aids, 3 Coating Systems & Additives, 3 Film Formers & Plasticizers, 2 API Stability Enhancers, 2 Surfactant & Foaming Agents, 2 Lubricants & Glidants, 1 Granulation, 1 Rheology Modifiers

excipientsByApplications
14 Solubilizers
10 Parenteral
10 Topical
9 Thickeners and Stabilizers
8 Direct Compression
6 Fillers, Diluents & Binders
5 Taste Masking
5 Controlled & Modified Release
5 Emulsifying Agents
4 Co-Processed Excipients
3 Chewable & Orodispersible Aids
3 Coating Systems & Additives
3 Film Formers & Plasticizers
2 API Stability Enhancers
2 Surfactant & Foaming Agents
2 Lubricants & Glidants
1 Granulation
1 Rheology Modifiers

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 Finished Drug Prices

globalSalesInformation
2 Finished Drug Prices

MARKET PLACE

26 APIs

marketPlace
26 APIs

REF. STANDARDS & IMPURITIES

3 EDQM , 1 USP , 1 Others

otherSolutions
3 EDQM
1 USP
1 Others

ANALYTICAL

1 Analytical Methods

otherMethods
1 Analytical Methods

Suanfarma Oxytetracycline Hydrochloride

Synopsis

ACTIVE PHARMA INGREDIENTS

32

API Suppliers

13

USDMF

13

CEP/COS

CEP/COS Certifications

3

JDMF

1

EU WC

0

KDMF

8

NDC API

13

VMF

7

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 40

MARKET PLACE

26

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

31

FDF Dossiers

13

FDA Orange Book

FDA (Orange Book)

2

Europe

9

Canada

0

Australia

0

South Africa

7

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

3

EDQM

1

USP

0

JP

1

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

1

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

NA

Annual Reports (USD Million)

NA

Finished Drug Prices

51 RELATED EXCIPIENT COMPANIES

93EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 2058-46-0, Oxytetracycline hcl, Terramycin hydrochloride, Oxytetracycline.hcl, Bisolvomycin, Terramycin

Molecular Formula

C₂₂H₂₅ClN₂O₉

Molecular Weight

496.9 g/mol

InChI Key

SVDOODSCHVSYEK-IFLJXUKPSA-N

FDA UNII

4U7K4N52ZM

Oxytetracycline Hydrochloride

A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.

1 2D Structure

Oxytetracycline Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

2.1.2 InChI

InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1

2.1.3 InChI Key

SVDOODSCHVSYEK-IFLJXUKPSA-N

2.1.4 Canonical SMILES

CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl

2.1.5 Isomeric SMILES

C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl

2.2 Other Identifiers

2.2.1 UNII

4U7K4N52ZM

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Bisolvomycin

2. Geomycin

3. Hydroxytetracycline

4. Oxyterracin

5. Oxyterracine

6. Oxytetracid

7. Oxytetracycline

8. Oxytetracycline Anhydrous

9. Oxytetracycline Calcium

10. Oxytetracycline Dihydrate

11. Oxytetracycline Monohydrochloride

12. Oxytetracycline Sulfate (2:1)

13. Oxytetracycline, (4a Beta,5 Beta,5a Beta,12a Beta)-isomer

14. Oxytetracycline, (5 Beta)-isomer

15. Oxytetracycline, Anhydrous

16. Oxytetracycline, Calcium (1:1) Salt

17. Oxytetracycline, Disodium Salt, Dihydrate

18. Oxytetracycline, Sodium Salt

19. Terramycin

2.3.2 Depositor-Supplied Synonyms

1. 2058-46-0

2. Oxytetracycline Hcl

3. Terramycin Hydrochloride

4. Oxytetracycline.hcl

5. Bisolvomycin

6. Terramycin

7. Dalimycin

8. Unimycin

9. Oxy-kesso-tetra

10. Alamycin

11. Imperacin

12. Mepatar

13. Oxacycline

14. Oxymykoin

15. Oxysteclin

16. Vendarcin

17. Oxytetracyclini Hydrochloridum

18. Dalinmycin

19. Engemycin

20. Oxamycen

21. Liquamycin Injectable

22. Aquacycline

23. Hydrocyclin

24. Oxybiocycline

25. Abbocin

26. Chrysocin

27. Elinton

28. Intaloxin

29. Liquachel

30. Macodyn

31. Otetryn

32. Oxlopar

33. Oxycycline

34. Oxyject

35. Oxytetral

36. Oxytetrin

37. Oxytracyl

38. Terraject

39. Toxinal

40. Biotet

41. Oxyvet

42. Oxy-dumocyclin

43. Tetra-tablinen

44. Oxy-terachel

45. Bi Steclin

46. Ia-loxin

47. Oxy-rivo

48. Uri-tet

49. Tetran Hydrochloride

50. 5-hydroxytetracycline Hydrochloride

51. Stecsolin

52. Oxydon

53. Tm 5

54. Oxy-tet 50

55. Tetracycline, 5-oxy-

56. Oxy-ws

57. Oxytetracycline (hydrochloride)

58. 4u7k4n52zm

59. Nsc 9169

60. Biosolvomycin

61. Chebi:31953

62. Oxy-de 250

63. 5-hydroxytetracycline Monohydrochloride

64. 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride

65. Ncgc00091268-01

66. Oxytet

67. Terramycin (tn)

68. Dsstox_cid_1097

69. Component Of Terramycin Topical Ointment

70. Dsstox_rid_75939

71. Dsstox_gsid_21097

72. (4s,4ar,5s,5ar,6s,12ar)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

73. Oxy Ws

74. Oxyject 100

75. Caswell No. 628

76. Oxytetracycline Hydrochloride 100 Microg/ml In Acetonitrile

77. Oxatet

78. Hydroxytetrazyklinhydrochlorid

79. Ccris 200

80. Cas-2058-46-0

81. Tm 5 (van)

82. Nsc-757262

83. (4s,4ar,5s,5ar,6s,12as)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Hydrochloride

84. Einecs 218-161-2

85. Epa Pesticide Chemical Code 006308

86. Unii-4u7k4n52zm

87. Neo-oxy 100/100 Mr

88. Ai3-50164

89. Oxytetracycline Hydrochloride (internal Use)

90. (4s,4ar,5s,5ar,6s,12as)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

91. Oxytetracycline Hydrochloride [jan]

92. Oxytetracycline Hydrochloride [usp:jan]

93. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s,4ar,5s,5ar,6s,12as)-

94. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-

95. Schembl124996

96. Spectrum1500457

97. Chembl1607480

98. Chembl4549546

99. Chembl4591469

100. Dtxsid5021097

101. Hy-b0275a

102. Hms1920f04

103. Pharmakon1600-01500457

104. Tox21_111109

105. Tox21_201850

106. Tox21_300601

107. Ccg-40206

108. Mfcd00135815

109. Nsc757262

110. S5199

111. Oxytetracycline For System Suitability

112. Akos015950811

113. Nc00526

114. Ncgc00164443-01

115. Ncgc00254367-01

116. Ncgc00259399-01

117. (4s,5s,6s,12as,4ar,5ar)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl -1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide, Chloride

118. Ac-11614

119. Oxytetracycline Hydrochloride (jp17/usp)

120. Oxytetracycline Hydrochloride [mi]

121. Cs-0013151

122. O0475

123. Oxytetracycline Hydrochloride [mart.]

124. Oxytetracycline Hydrochloride [vandf]

125. Oxytetracycline Hydrochloride [usp-rs]

126. Oxytetracycline Hydrochloride [who-dd]

127. Oxytetracycline Hydrochloride [who-ip]

128. D01596

129. Oxytetracycline Hydrochloride [green Book]

130. Oxytetracycline Hydrochloride [orange Book]

131. Oxytetracycline Hydrochloride [ep Monograph]

132. Oxytetracycline Hydrochloride [usp Monograph]

133. Oxytetracyclini Hydrochloridum [who-ip Latin]

134. Q27114732

135. Oxytetracycline Hydrochloride, >=95% (hplc), Crystalline

136. Terra-cortril Component Oxytetracycline Hydrochloride

137. Oxytetracycline Hydrochloride Component Of Terra-cortril

138. Oxytetracycline Hydrochloride, Vetranal(tm), Analytical Standard

139. Oxytetracycline Hydrochloride, European Pharmacopoeia (ep) Reference Standard

140. Oxytetracycline Hydrochloride, United States Pharmacopeia (usp) Reference Standard

141. 15000-39-2

142. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Hydrochloride (1:1), (4s,4ar,5s,5ar,6s,12as)-

143. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4.alpha.,4a.alpha.,5.alpha.,5a.alpha.,6.beta.,12a.alpha.))-

144. Oxytetracycline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date

2011-12-26

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₅ClN₂O₉
Molecular Weight	496.9 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	2
Exact Mass	496.1248581 g/mol
Monoisotopic Mass	496.1248581 g/mol
Topological Polar Surface Area	202 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	1000
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

API SUPPLIERS

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USDMF

01

Cipan - Companhia Industrial Produto...

Spain

CPHI Middle east

Suanfarma, at the Core of a Better Life.

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Spain

Digital Content

Oxytetracycline Hydrochloride

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 13390

Submission : 1998-09-01

Status : Active

Type : II

Product Web Link

Digital Content

02

Century Pharmaceuticals Ltd

India

Medlab Asia & Asia Health

Not Confirmed

Century has been an API manufacturer for over 30 years & is the partner of choice for multipurpose custom manufacturing projects.

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India

Digital Content

Oxytetracycline Hydrochloride Usp

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 34794

Submission : 2020-07-22

Status : Active

Type : II

Century Company Banner

Product Web Link

Digital Content

03

Fermic Sa De Cv

Mexico

Medlab Asia & Asia Health

Not Confirmed

04

Pfizer Inc

U.S.A

Medlab Asia & Asia Health

Not Confirmed

05

Pfizer Inc

U.S.A

Medlab Asia & Asia Health

Not Confirmed

06

Pfizer Inc

U.S.A

Medlab Asia & Asia Health

Not Confirmed

07

Pfizer Inc

U.S.A

Medlab Asia & Asia Health

Not Confirmed

08

Pfizer Inc

U.S.A

Medlab Asia & Asia Health

Not Confirmed

09

Pliva

Croatia

Medlab Asia & Asia Health

Not Confirmed

10

Amfair Inc

Country

Medlab Asia & Asia Health

Not Confirmed

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API Reference Price

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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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