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    Chemistry

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    Also known as: 2058-46-0, Oxytetracycline hcl, Terramycin hydrochloride, Oxytetracycline.hcl, Bisolvomycin, Terramycin
    Molecular Formula
    C22H25ClN2O9
    Molecular Weight
    496.9  g/mol
    InChI Key
    SVDOODSCHVSYEK-IFLJXUKPSA-N
    FDA UNII
    4U7K4N52ZM
    Oxytetracycline Hydrochloride
    A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
    1 2D Structure

    Oxytetracycline Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1
    2.1.3 InChI Key
    SVDOODSCHVSYEK-IFLJXUKPSA-N
    2.1.4 Canonical SMILES
    CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl
    2.1.5 Isomeric SMILES
    C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    4U7K4N52ZM
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Bisolvomycin

    2. Geomycin

    3. Hydroxytetracycline

    4. Oxyterracin

    5. Oxyterracine

    6. Oxytetracid

    7. Oxytetracycline

    8. Oxytetracycline Anhydrous

    9. Oxytetracycline Calcium

    10. Oxytetracycline Dihydrate

    11. Oxytetracycline Monohydrochloride

    12. Oxytetracycline Sulfate (2:1)

    13. Oxytetracycline, (4a Beta,5 Beta,5a Beta,12a Beta)-isomer

    14. Oxytetracycline, (5 Beta)-isomer

    15. Oxytetracycline, Anhydrous

    16. Oxytetracycline, Calcium (1:1) Salt

    17. Oxytetracycline, Disodium Salt, Dihydrate

    18. Oxytetracycline, Sodium Salt

    19. Terramycin

    2.3.2 Depositor-Supplied Synonyms

    1. 2058-46-0

    2. Oxytetracycline Hcl

    3. Terramycin Hydrochloride

    4. Oxytetracycline.hcl

    5. Bisolvomycin

    6. Terramycin

    7. Dalimycin

    8. Unimycin

    9. Oxy-kesso-tetra

    10. Alamycin

    11. Imperacin

    12. Mepatar

    13. Oxacycline

    14. Oxymykoin

    15. Oxysteclin

    16. Vendarcin

    17. Oxytetracyclini Hydrochloridum

    18. Dalinmycin

    19. Engemycin

    20. Oxamycen

    21. Liquamycin Injectable

    22. Aquacycline

    23. Hydrocyclin

    24. Oxybiocycline

    25. Abbocin

    26. Chrysocin

    27. Elinton

    28. Intaloxin

    29. Liquachel

    30. Macodyn

    31. Otetryn

    32. Oxlopar

    33. Oxycycline

    34. Oxyject

    35. Oxytetral

    36. Oxytetrin

    37. Oxytracyl

    38. Terraject

    39. Toxinal

    40. Biotet

    41. Oxyvet

    42. Oxy-dumocyclin

    43. Tetra-tablinen

    44. Oxy-terachel

    45. Bi Steclin

    46. Ia-loxin

    47. Oxy-rivo

    48. Uri-tet

    49. Tetran Hydrochloride

    50. 5-hydroxytetracycline Hydrochloride

    51. Stecsolin

    52. Oxydon

    53. Tm 5

    54. Oxy-tet 50

    55. Tetracycline, 5-oxy-

    56. Oxy-ws

    57. Oxytetracycline (hydrochloride)

    58. 4u7k4n52zm

    59. Nsc 9169

    60. Biosolvomycin

    61. Chebi:31953

    62. Oxy-de 250

    63. 5-hydroxytetracycline Monohydrochloride

    64. 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride

    65. Ncgc00091268-01

    66. Oxytet

    67. Terramycin (tn)

    68. Dsstox_cid_1097

    69. Component Of Terramycin Topical Ointment

    70. Dsstox_rid_75939

    71. Dsstox_gsid_21097

    72. (4s,4ar,5s,5ar,6s,12ar)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

    73. Oxy Ws

    74. Oxyject 100

    75. Caswell No. 628

    76. Oxytetracycline Hydrochloride 100 Microg/ml In Acetonitrile

    77. Oxatet

    78. Hydroxytetrazyklinhydrochlorid

    79. Ccris 200

    80. Cas-2058-46-0

    81. Tm 5 (van)

    82. Nsc-757262

    83. (4s,4ar,5s,5ar,6s,12as)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Hydrochloride

    84. Einecs 218-161-2

    85. Epa Pesticide Chemical Code 006308

    86. Unii-4u7k4n52zm

    87. Neo-oxy 100/100 Mr

    88. Ai3-50164

    89. Oxytetracycline Hydrochloride (internal Use)

    90. (4s,4ar,5s,5ar,6s,12as)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

    91. Oxytetracycline Hydrochloride [jan]

    92. Oxytetracycline Hydrochloride [usp:jan]

    93. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s,4ar,5s,5ar,6s,12as)-

    94. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-

    95. Schembl124996

    96. Spectrum1500457

    97. Chembl1607480

    98. Chembl4549546

    99. Chembl4591469

    100. Dtxsid5021097

    101. Hy-b0275a

    102. Hms1920f04

    103. Pharmakon1600-01500457

    104. Tox21_111109

    105. Tox21_201850

    106. Tox21_300601

    107. Ccg-40206

    108. Mfcd00135815

    109. Nsc757262

    110. S5199

    111. Oxytetracycline For System Suitability

    112. Akos015950811

    113. Nc00526

    114. Ncgc00164443-01

    115. Ncgc00254367-01

    116. Ncgc00259399-01

    117. (4s,5s,6s,12as,4ar,5ar)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl -1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide, Chloride

    118. Ac-11614

    119. Oxytetracycline Hydrochloride (jp17/usp)

    120. Oxytetracycline Hydrochloride [mi]

    121. Cs-0013151

    122. O0475

    123. Oxytetracycline Hydrochloride [mart.]

    124. Oxytetracycline Hydrochloride [vandf]

    125. Oxytetracycline Hydrochloride [usp-rs]

    126. Oxytetracycline Hydrochloride [who-dd]

    127. Oxytetracycline Hydrochloride [who-ip]

    128. D01596

    129. Oxytetracycline Hydrochloride [green Book]

    130. Oxytetracycline Hydrochloride [orange Book]

    131. Oxytetracycline Hydrochloride [ep Monograph]

    132. Oxytetracycline Hydrochloride [usp Monograph]

    133. Oxytetracyclini Hydrochloridum [who-ip Latin]

    134. Q27114732

    135. Oxytetracycline Hydrochloride, >=95% (hplc), Crystalline

    136. Terra-cortril Component Oxytetracycline Hydrochloride

    137. Oxytetracycline Hydrochloride Component Of Terra-cortril

    138. Oxytetracycline Hydrochloride, Vetranal(tm), Analytical Standard

    139. Oxytetracycline Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    140. Oxytetracycline Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    141. 15000-39-2

    142. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Hydrochloride (1:1), (4s,4ar,5s,5ar,6s,12as)-

    143. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4.alpha.,4a.alpha.,5.alpha.,5a.alpha.,6.beta.,12a.alpha.))-

    144. Oxytetracycline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    2.4 Create Date
    2011-12-26
    3 Chemical and Physical Properties
    Molecular Weight 496.9 g/mol
    Molecular Formula C22H25ClN2O9
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count2
    Exact Mass496.1248581 g/mol
    Monoisotopic Mass496.1248581 g/mol
    Topological Polar Surface Area202 Ų
    Heavy Atom Count34
    Formal Charge0
    Complexity1000
    Isotope Atom Count0
    Defined Atom Stereocenter Count6
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

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LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"606.00","actualQuantity":"606","unit":"KGS","unitRateFc":"15.5","totalValueFC":"9552.7","currency":"USD","unitRateINR":"1321","date":"07-Sep-2024","totalValueINR":"800525","totalValueInUsd":"9552.7","indian_port":"JNPT","hs_no":"29413020","bill_no":"5474138","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"1-203 NO 337 SHAHE ROAD JIANGQIAO TOWN JIADING DISTRICT SHANGHAI CHINA CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727807400,"product":"OXYTETRACYCLINE HYDROCHLORIDE IP","address":"AGARWAL B2B CENTRE, 604 KANCHPADA","city":"MUMBAI","supplier":"ZHEJIANG XIHE IMPORT ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN RISE ENTERPRISES","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"11","totalValueFC":"55470.3","currency":"USD","unitRateINR":"932.2","date":"02-Oct-2024","totalValueINR":"4660980","totalValueInUsd":"55470.3","indian_port":"JNPT","hs_no":"29413020","bill_no":"5915833","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM 606, BUILDING 4, 188 ZIJINGHUA NORTH ROAD, WEST LAKE DISTRICT,HANGZHOU ZHEJIANG PROVINCE CN","customerAddress":"AGARWAL B2B CENTRE, 604 KANCHPADA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729794600,"product":"OXYTETRACYCLINE HYDROCHLORIDE (VET) IP.","address":"48, CHANDRA GUPTA ESTATE,","city":"MUMBAI, MAHARASHTRA.","supplier":"BRILLIANT PHARMACEUTICAL LIMITED.","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GORANG INTERNATIONAL","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"10.6","totalValueFC":"53391.5","currency":"USD","unitRateINR":"897.3","date":"25-Oct-2024","totalValueINR":"4486307.72","totalValueInUsd":"53391.5","indian_port":"JNPT","hs_no":"29413020","bill_no":"6327245","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"OFFICE F, 32\/F, PLAZA 88 NO.88 YEUN G UK ROAD, TSUEN WAN NT, HONG KONG CHINA ., ., China China","customerAddress":"48, CHANDRA GUPTA ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729794600,"product":"OXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNATIONAL TRADING COMPANY LIMITED)IUPAC NAME: (4S,4AR,5S,5AR,6S,OXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNAT","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"11","totalValueFC":"11120.9","currency":"USD","unitRateINR":"934.5","date":"25-Oct-2024","totalValueINR":"934450","totalValueInUsd":"11120.9","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29413020","bill_no":"6326478","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"305 AGGARWAL CITY SQUARE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729881000,"product":"OXYTETRACYCLINE HYDROCHLORIDE,ORAL GRADE","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"JIANGSU GUOTAI GUOMIAN ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"494.00","actualQuantity":"494","unit":"KGS","unitRateFc":"10.6","totalValueFC":"5291.3","currency":"USD","unitRateINR":"900","date":"26-Oct-2024","totalValueINR":"444606.48","totalValueInUsd":"5291.3","indian_port":"JNPT","hs_no":"29413020","bill_no":"6355810","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"LTD. 19-21\/F, GUOTAI BLDG, RENMIN ROAD(M). ZHANGJIAGANG CITY, JIANGSU, CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729881000,"product":"OXYTETRACYCLINE HYDROCHLORIDE,ORAL GRADE","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"JIANGSU GUOTAI GUOMIAN ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"494.00","actualQuantity":"494","unit":"KGS","unitRateFc":"10.6","totalValueFC":"5291.3","currency":"USD","unitRateINR":"900","date":"26-Oct-2024","totalValueINR":"444606.48","totalValueInUsd":"5291.3","indian_port":"JNPT","hs_no":"29413020","bill_no":"6356094","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"LTD. 19-21\/F, GUOTAI BLDG, RENMIN ROAD(M). ZHANGJIAGANG CITY, JIANGSU, CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729881000,"product":"OXYTETRACYCLINE HYDROCHLORIDE,ORAL GRADE","address":"213, LAXMI PLAZA, LAXMI INDL.","city":"MUMBAI, MAHARASHTRA","supplier":"JIANGSU GUOTAI GUOMIAN ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ASHISH LIFE SCIENCE PVT LIMITED","customerCountry":"INDIA","quantity":"1010.00","actualQuantity":"1010","unit":"KGS","unitRateFc":"10.6","totalValueFC":"10818.2","currency":"USD","unitRateINR":"900","date":"26-Oct-2024","totalValueINR":"909013.24","totalValueInUsd":"10818.2","indian_port":"JNPT","hs_no":"29413020","bill_no":"6355015","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"LTD. 19-21\/F, GUOTAI BLDG, RENMIN ROAD(M). ZHANGJIAGANG CITY, JIANGSU, CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."}]
    21-Jan-2021
    26-Oct-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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