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Chemistry

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Also known as: P-coumaric acid, 501-98-4, P-hydroxycinnamic acid, 4-coumaric acid, Trans-4-hydroxycinnamic acid, 7400-08-0
Molecular Formula
C9H8O3
Molecular Weight
164.16  g/mol
InChI Key
NGSWKAQJJWESNS-ZZXKWVIFSA-N
FDA UNII
IBS9D1EU3J

P-Coumaric Acid
trans-4-Coumaric acid is a metabolite found in or produced by Saccharomyces cerevisiae.
1 2D Structure

P-Coumaric Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(E)-3-(4-hydroxyphenyl)prop-2-enoic acid
2.1.2 InChI
InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+
2.1.3 InChI Key
NGSWKAQJJWESNS-ZZXKWVIFSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1C=CC(=O)O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1/C=C/C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
IBS9D1EU3J
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-coumaric Acid

2. 4-coumaric Acid, (e)-isomer

3. 4-coumaric Acid, (z)-isomer

4. 4-coumaric Acid, Disodium Salt

5. P-coumaric Acid

6. P-coumaryl Alcohol

7. P-hydroxycinnamic Acid

8. Para-coumaric Acid

9. Phenol, 4-(3-hydroxy-1-propenyl)-

10. Trans-3-(4'-hydroxyphenyl)-2-propenoic Acid

11. Trans-hppa

2.3.2 Depositor-Supplied Synonyms

1. P-coumaric Acid

2. 501-98-4

3. P-hydroxycinnamic Acid

4. 4-coumaric Acid

5. Trans-4-hydroxycinnamic Acid

6. 7400-08-0

7. Trans-p-coumaric Acid

8. P-cumaric Acid

9. 3-(4-hydroxyphenyl)acrylic Acid

10. Para-coumaric Acid

11. Hydroxycinnamic Acid

12. Naringeninic Acid

13. P-hydroxy-cinnamic Acid

14. (e)-p-coumaric Acid

15. (e)-3-(4-hydroxyphenyl)acrylic Acid

16. Trans-4-coumaric Acid

17. Trans-p-coumarinic Acid

18. 4'-hydroxycinnamic Acid

19. 2-propenoic Acid, 3-(4-hydroxyphenyl)-, (2e)-

20. P-hydroxyphenylacrylic Acid

21. Cinnamic Acid, P-hydroxy-

22. (e)-p-hydroxycinnamic Acid

23. Trans-p-hydroxycinnamic Acid

24. (e)-3-(4-hydroxyphenyl)prop-2-enoic Acid

25. 3-(4-hydroxyphenyl)-2-propenoic Acid

26. (2e)-3-(4-hydroxyphenyl)prop-2-enoic Acid

27. 4-coumarate

28. Trans-p-hydroxycinnamate

29. 2-propenoic Acid, 3-(4-hydroxyphenyl)-

30. 4-hydroxycinnamate

31. Cinnamic Acid, P-hydroxy-, (e)-

32. (e)-3-(4-hydroxyphenyl)-2-propenoic Acid

33. Trans-4-hydroxycinnamate

34. (2e)-3-(4-hydroxyphenyl)acrylic Acid

35. Beta-(4-hydroxyphenyl)acrylic Acid

36. Para Coumaric Acid

37. (e)-4-hydroxycinnamic Acid

38. Nsc 59260

39. 3-(4-hydroxyphenyl)prop-2-enoic Acid

40. 4-hydroxycinamic Acid

41. Ibs9d1eu3j

42. 2-propenoic Acid, 3-(4-hydroxyphenyl)-, (e)-

43. 4-hydroxy Cinnamic Acid

44. Chembl66879

45. Chebi:32374

46. Beta-[4-hydroxyphenyl]acrylic Acid

47. Nsc-59260

48. Nsc674321

49. 2-propenoic Acid, 3-(4-hydroxyphenyl)-, Homopolymer

50. Nsc-674321

51. 50940-26-6

52. Trans-p-coumarate

53. 3-(4-hydroxyphenyl)acrylate

54. Coumaric Acids

55. Mfcd00004399

56. .beta.-[4-hydroxyphenyl]acrylic Acid

57. Parahydroxycinnamic Acid

58. (e)-3-[4-hydroxyphenyl]-2-propenoic Acid

59. Trans-p-cumaric Acid

60. .beta.-(4-hydroxyphenyl)acrylic Acid

61. 2-propenoic Acid, 3-(4-hydroxyphenyl)-, (z)-

62. Einecs 231-000-0

63. Unii-ibs9d1eu3j

64. Nsc 674321

65. Chebi:36090

66. Brn 2207381

67. Brn 2207383

68. Hydroxycinnamate

69. Para Coumarate

70. P-coumaric-acid

71. Para-coumarate

72. P-cumarate

73. Naringeninic-acid

74. P-hydroxycinnamate

75. 4qem

76. Coumaric Acid, P-

77. 4'-hydroxycinnamate

78. 4-hydroxy Cinnamate

79. P-coumaric Acid,trans

80. Oristar Pca

81. P-coumaric Acid 98%

82. 4f8j

83. P-coumaric Acid, Trans

84. 4-hydroxyphenylpropenoate

85. (2e)-3-(4-hydroxyphenyl)-2-propenoic Acid

86. Bmse000150

87. Bmse000591

88. Bmse010208

89. Trans-4-hydroxycinnamicacid

90. B-[4-hydroxyphenyl]acrylate

91. Schembl39106

92. P-hydroxycinnamic Acid (m4)

93. 0-10-00-00297 (beilstein Handbook Reference)

94. 4-10-00-01005 (beilstein Handbook Reference)

95. Mls001066419

96. P-hydroxycinnamic Acid, Trans

97. P-coumaric Acid [mi]

98. Beta-[4-hydroxyphenyl]acrylate

99. Bdbm4374

100. Gtpl5787

101. Para Hydroxycinnamic Acid

102. Sodium2,4-pentanedionate

103. B-[4-hydroxyphenyl]acrylic Acid

104. Trans-p-hydroxyzimtsa Currencyure

105. Zinc39811

106. Dtxsid30901076

107. P-coumaric Acid [who-dd]

108. Hms1409e10

109. 3-(4-hydroxyphenyl)-2-propenoate

110. Hydroxycinnamic Acid [inci]

111. Bcp22803

112. Hy-n2391

113. Nsc59260

114. Str06515

115. 4-hydroxyphenylpropenoic Acid

116. Cinnamic Acid, 4-hydroxy-, Trans-

117. Ac7957

118. Bbl012226

119. Ck2547

120. S4759

121. S9564

122. Stl163567

123. Akos000120685

124. P-coumaric Acid;p-hydroxycinnamic Acid

125. Bcp9001042

126. Ccg-266309

127. Cs-w020394

128. Db04066

129. P-coumaric Acid, >=98.0% (hplc)

130. (e)-3-(4-hydroxyphenyl)prop-2-enoate

131. Ncgc00246974-01

132. Ac-10318

133. Ac-34130

134. Ac-34133

135. As-12000

136. Bp-13278

137. Smr000112201

138. Trans-p-coumaric Acid, Analytical Standard

139. Am20050138

140. N1817

141. A14559

142. A19490

143. C00811

144. Q99374

145. (2e)-3-(4-hydroxyphenyl)-2-propenoic Acid #

146. 400h080

147. A828008

148. Ae-562/40414679

149. Trans-p-coumaric Acid 1000 Microg/ml In Acetone

150. Q-100560

151. W-104438

152. 0c1bff2d-2cf7-4fc1-9f76-3268c2c7f783

153. F2191-0188

154. P-coumaric Acid, Primary Pharmaceutical Reference Standard

155. P-coumaric Acid Methyl Ester Geometric Isomer (tentative, Mse)

156. (e)-3-(4-hydroxyphenyl)prop-2-enoate;trans-4-hydroxycinnamic Acid

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 164.16 g/mol
Molecular Formula C9H8O3
XLogP31.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass164.047344113 g/mol
Monoisotopic Mass164.047344113 g/mol
Topological Polar Surface Area57.5 Ų
Heavy Atom Count12
Formal Charge0
Complexity178
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)


Contraceptive Agents, Male

Chemical substances or agents with contraceptive activity in males. Use for male contraceptive agents in general or for which there is no specific heading. (See all compounds classified as Contraceptive Agents, Male.)


Free Radical Scavengers

Substances that eliminate free radicals. Among other effects, they protect PANCREATIC ISLETS against damage by CYTOKINES and prevent myocardial and pulmonary REPERFUSION INJURY. (See all compounds classified as Free Radical Scavengers.)


ANALYTICAL

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ABOUT THIS PAGE

P-Coumaric Acid Manufacturers

A P-Coumaric Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of P-Coumaric Acid, including repackagers and relabelers. The FDA regulates P-Coumaric Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. P-Coumaric Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

P-Coumaric Acid Suppliers

A P-Coumaric Acid supplier is an individual or a company that provides P-Coumaric Acid active pharmaceutical ingredient (API) or P-Coumaric Acid finished formulations upon request. The P-Coumaric Acid suppliers may include P-Coumaric Acid API manufacturers, exporters, distributors and traders.

P-Coumaric Acid GMP

P-Coumaric Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of P-Coumaric Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right P-Coumaric Acid GMP manufacturer or P-Coumaric Acid GMP API supplier for your needs.

P-Coumaric Acid CoA

A P-Coumaric Acid CoA (Certificate of Analysis) is a formal document that attests to P-Coumaric Acid's compliance with P-Coumaric Acid specifications and serves as a tool for batch-level quality control.

P-Coumaric Acid CoA mostly includes findings from lab analyses of a specific batch. For each P-Coumaric Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

P-Coumaric Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (P-Coumaric Acid EP), P-Coumaric Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (P-Coumaric Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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