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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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MARKET PLACE

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API

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FDF

0INTERMEDIATES

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FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Listed Dossiers

Listed Dossiers

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FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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USP

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US Patents

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GLOBAL SALES INFORMATION

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Chemistry

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Also known as: 23180-57-6, Peoniflorin, Paeonia moutan, Paeony root, Nsc 178886, 21aiq4ev64
Molecular Formula
C23H28O11
Molecular Weight
480.5  g/mol
InChI Key
YKRGDOXKVOZESV-WRJNSLSBSA-N
FDA UNII
21AIQ4EV64

Paeoniflorin
paeoniflorin is a natural product found in Paeonia, Paeonia tenuifolia, and other organisms with data available.
1 2D Structure

Paeoniflorin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(1R,2S,3R,5R,6R,8S)-6-hydroxy-8-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl benzoate
2.1.2 InChI
InChI=1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1
2.1.3 InChI Key
YKRGDOXKVOZESV-WRJNSLSBSA-N
2.1.4 Canonical SMILES
CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O
2.1.5 Isomeric SMILES
C[C@]12C[C@@]3([C@@H]4C[C@]1([C@@]4([C@H](O2)O3)COC(=O)C5=CC=CC=C5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
21AIQ4EV64
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Peoniflorin

2. Peoniflorin Sulfonate

2.3.2 Depositor-Supplied Synonyms

1. 23180-57-6

2. Peoniflorin

3. Paeonia Moutan

4. Paeony Root

5. Nsc 178886

6. 21aiq4ev64

7. ((2s,2ar,2a1s,3ar,4r,5ar)-4-hydroxy-2-methyl-2a-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)hexahydro-2h-1,5-dioxa-2,4-methanocyclobuta[cd]pentalen-2a1-yl)methyl Benzoate

8. Unii-21aiq4ev64

9. Ccris 6494

10. Nsc178886

11. Nsc-178886

12. .beta.-d-glucopyranoside, (1ar,2s,3ar,5r,5ar,5bs)-5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl

13. .beta.-d-glucopyranoside, (1ar,2s,3ar,5r,5ar,5bs)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta[cd]pentalen-1a(2h)-yl

14. Einecs 245-476-2

15. Mfcd00869331

16. Peoniflorin [inci]

17. Paeoniflorin [usp-rs]

18. Schembl549033

19. Chebi:7889

20. Chembl4303209

21. Dtxsid2042648

22. Paeoniflorin, Analytical Standard

23. Paeoniflorin, >=98% (hplc)

24. Hms3884d17

25. Hy-n0293

26. Zinc8234328

27. S2410

28. Akos025311455

29. Ccg-269549

30. As-12193

31. Beta-d-glucopyranoside, (1as,2r,3ar,5r,5ar,5bs)-5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl

32. C09959

33. Ab01566855_01

34. 180p576

35. Q-100296

36. Q7124104

37. ((2s,2ar,2a1s,3ar,4r,5ar)-4-hydroxy-2-methyl-2a-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)hexahydro-2h-1,5-dioxa-2,4-methanocyclobuta[cd]pentalen-2a1-yl)methylbenzoate

38. .beta.-d-glucopyranoside, 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl, (1ar-(1a.alpha.,2.beta.,3a.alpha.,5.alpha.,5a.alpha.,5b.alpha.))-

39. [(1r,2s,3r,5r,6r,8s)-6-hydroxy-8-methyl-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl Benzoate

40. [hydroxy-methyl-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-[?]yl]methyl Benzoate

41. 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-lh-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl-beta-d-glucopyranoside

42. B-d-glucopyranoside,(1ar,2s,3ar,5r,5ar,5bs)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta[cd]pentalen-1a(2h)-yl

43. Beta-d-glucopyranoside, 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl, (1ar-(1a-alpha,2-beta,3a-alpha,5-alpha,5a-alpha,5b-alpha))-

44. Beta-d-glucopyranoside, 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl, (1ar-(1aalpha,2beta,3aalpha,5alpha,5aalpha,5balpha))-

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 480.5 g/mol
Molecular Formula C23H28O11
XLogP3-1
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count11
Rotatable Bond Count7
Exact Mass480.16316171 g/mol
Monoisotopic Mass480.16316171 g/mol
Topological Polar Surface Area164 Ų
Heavy Atom Count34
Formal Charge0
Complexity849
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


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ABOUT THIS PAGE

Paeoniflorin Manufacturers

A Paeoniflorin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Paeoniflorin, including repackagers and relabelers. The FDA regulates Paeoniflorin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Paeoniflorin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Paeoniflorin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Paeoniflorin Suppliers

A Paeoniflorin supplier is an individual or a company that provides Paeoniflorin active pharmaceutical ingredient (API) or Paeoniflorin finished formulations upon request. The Paeoniflorin suppliers may include Paeoniflorin API manufacturers, exporters, distributors and traders.

click here to find a list of Paeoniflorin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Paeoniflorin GMP

Paeoniflorin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Paeoniflorin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Paeoniflorin GMP manufacturer or Paeoniflorin GMP API supplier for your needs.

Paeoniflorin CoA

A Paeoniflorin CoA (Certificate of Analysis) is a formal document that attests to Paeoniflorin's compliance with Paeoniflorin specifications and serves as a tool for batch-level quality control.

Paeoniflorin CoA mostly includes findings from lab analyses of a specific batch. For each Paeoniflorin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Paeoniflorin may be tested according to a variety of international standards, such as European Pharmacopoeia (Paeoniflorin EP), Paeoniflorin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Paeoniflorin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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