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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Palmidrol, 544-31-0, N-(2-hydroxyethyl)hexadecanamide, Palmitoyl ethanolamide, Impulsin, Palmitamide mea
Molecular Formula
C18H37NO2
Molecular Weight
299.5  g/mol
InChI Key
HXYVTAGFYLMHSO-UHFFFAOYSA-N
FDA UNII
6R8T1UDM3V

Palmitoylethanolamide
Palmitoyl ethanolamide is a metabolite found in the aging mouse brain.
1 2D Structure

Palmitoylethanolamide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-(2-hydroxyethyl)hexadecanamide
2.1.2 InChI
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
2.1.3 InChI Key
HXYVTAGFYLMHSO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCCCCCCCCCCCCCC(=O)NCCO
2.2 Other Identifiers
2.2.1 UNII
6R8T1UDM3V
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Impulsin

2. Mimyx

3. N-(2-hydroxyethyl)palmitate

4. N-palmitoylethanolamine

5. Palmidrol

6. Palmitylethanolamide

2.3.2 Depositor-Supplied Synonyms

1. Palmidrol

2. 544-31-0

3. N-(2-hydroxyethyl)hexadecanamide

4. Palmitoyl Ethanolamide

5. Impulsin

6. Palmitamide Mea

7. N-palmitoylethanolamine

8. Loramine P 256

9. Hydroxyethylpalmitamide

10. Palmitic Acid Monoethanolamide

11. N-(2-hydroxyethyl)palmitamide

12. Palmitoyl-ea

13. Palmitylethanolamide

14. Palmidrolum

15. Hexadecanamide, N-(2-hydroxyethyl)-

16. Palmidrol [inn]

17. Monoethanolamine Palmitic Acid Amide

18. Levagen

19. Anandamide (16:0)

20. N-palmitoyl Ethanolamine

21. Palmitic Monoethanolamide

22. Palmdrol Prodes

23. N-hexadecanoylethanolamine

24. Palmitinsaeure-beta-hydroxyethylamid

25. Nsc 23320

26. Hexadecanoyl Ethanolamide

27. Nsc-23320

28. N-hexadecanoyl-ethanolamine

29. N(2-hydroxyethyl)palmitide

30. Am 3112

31. 6r8t1udm3v

32. N(2-hydroxyethyl) Palmitide

33. N-(2-hydroxyethyl)-palmitide

34. Chebi:71464

35. Fsd-201

36. Palmidrol (inn)

37. Ncgc00015793-03

38. Am 3112;loramine P 256;mackpeart Dr 14v

39. Dsstox_cid_22254

40. Dsstox_rid_79975

41. Dsstox_gsid_42254

42. Mimyx

43. Palmidrolum [inn-latin]

44. Cas-544-31-0

45. Sr-01000076055

46. Einecs 208-867-9

47. Unii-6r8t1udm3v

48. N-(2-hydroxyethyl) Hexadecanamide

49. Hexadecanamide,n-(2-hydroxyethyl)-

50. Mackpeart Dr 14v

51. Mfcd00020562

52. Anandamide C16:0

53. 2-palmitoylaminoethanol

54. Palmdrol Prodes (tn)

55. Tocris-0879

56. N-palmitoyl Ethanolamide

57. N-hexadecyl-ethanolamine

58. Palmidrol [mi]

59. Lopac-p-0359

60. Palmidrol [mart.]

61. Palmitoylethanolamide-[d4]

62. Palmityoletanolamide (pea)

63. 2-palmitamidoethanol

64. Palmidrol [who-dd]

65. Cbiol_002043

66. Lopac0_000905

67. Bspbio_001454

68. Kbiogr_000174

69. Kbioss_000174

70. Mls002153421

71. Schembl120518

72. Palmitamide Mea [inci]

73. Bml2-b10

74. Chembl417675

75. Gtpl3622

76. Am-3112

77. Dtxsid4042254

78. Palmidrol

79. N-palmitoylethanolamine

80. Schembl19511663

81. Bdbm29083

82. Kbio2_000174

83. Kbio2_002742

84. Kbio2_005310

85. Kbio3_000347

86. Kbio3_000348

87. Bio1_000329

88. Bio1_000818

89. Bio1_001307

90. Bio2_000174

91. Bio2_000654

92. Hms1361i16

93. Hms1791i16

94. Hms1989i16

95. Hms2234l19

96. Hms3264c10

97. Hms3266n08

98. Hms3374k03

99. Hms3402i16

100. Hms3411b14

101. Hms3649l03

102. Hms3675b14

103. Pharmakon1600-01506156

104. Bcp29005

105. Cs-d1253

106. Nsc23320

107. Zinc8035017

108. Tox21_110222

109. Ana(16:0)

110. Lmfa08040013

111. Nae(16:0)

112. Nsc760371

113. S4708

114. Stl454872

115. Akos002676363

116. Tox21_110222_1

117. Ccg-204987

118. Db14043

119. Lp00905

120. Nsc-760371

121. Sdccgsbi-0050880.p002

122. Idi1_033924

123. S10398

124. Ncgc00015793-01

125. Ncgc00015793-02

126. Ncgc00015793-04

127. Ncgc00015793-05

128. Ncgc00015793-06

129. Ncgc00015793-07

130. Ncgc00015793-08

131. Ncgc00015793-09

132. Ncgc00015793-10

133. Ncgc00015793-12

134. Ncgc00024840-01

135. Ncgc00024840-02

136. Ncgc00024840-05

137. Ncgc00024840-06

138. Ncgc00024840-07

139. Ncgc00024840-08

140. Ncgc00024840-09

141. As-14094

142. Hy-20685

143. Palmitoylethanolamide [nflis-drug]

144. Smr000058371

145. Hexadecanoic Acid (2-hydroxy-ethyl)-amide

146. B6485

147. Eu-0100905

148. Ft-0778178

149. P2670

150. D08328

151. P 0359

152. Ab00918319_06

153. A904411

154. Q2159860

155. Sr-01000076055-1

156. Sr-01000076055-3

157. Sr-01000076055-7

158. Brd-k68095457-001-04-4

159. Z2687203832

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 299.5 g/mol
Molecular Formula C18H37NO2
XLogP36.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count16
Exact Mass299.282429423 g/mol
Monoisotopic Mass299.282429423 g/mol
Topological Polar Surface Area49.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity219
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cannabinoid Receptor Agonists

Compounds that interact with and stimulate the activity of CANNABINOID RECEPTORS. (See all compounds classified as Cannabinoid Receptor Agonists.)


Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


API SUPPLIERS

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01

Laboratorium Ofichem B.V

Netherlands

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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  • EDQM
  • WHO-GMP

Virtual BoothLaboratorium Ofichem, offering a flexible, high-tech environment to produce broad range of APIs for Human & Vet pharmaceutical markets.

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USDMF CEP/COS JDMF EU-WC NDC arrow-down KDMF VMF Others AUDIT
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02

ASolution Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothASolution Pharmaceuticals: Your Partner for cGMP Development & Manufacturing Services – Supplying APIs, FDFs, and Specialty Molecules.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
ASolution Pharmaceuticals

03

Allastir

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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04

Wuxi Further Pharmaceutical Co Ltd

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
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05

Zhejiang Bamboo Pharmaceuticals

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
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06

TBD Pharmatech

Estonia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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NDC API

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Ofichem BV

Netherlands
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothLaboratorium Ofichem, offering a flexible, high-tech environment to produce broad range of APIs for Human & Vet pharmaceutical markets.

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Digital Content Digital Content

PALMIDROL

NDC Package Code : 62675-1309

Start Marketing Date : 2018-07-02

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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Listed Suppliers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothLaboratorium Ofichem, offering a flexible, high-tech environment to produce broad range of APIs for Human & Vet pharmaceutical markets.

Flag Netherlands
Digital Content Digital Content

Palmitoylethanolamide

About the Company : Laboratorium Ofichem is a GMP-certified and FDA-approved API manufacturer with state-of-the-art development and production facilities in the Netherlands. We develop and manufacture...

Laboratorium Ofichem is a GMP-certified and FDA-approved API manufacturer with state-of-the-art development and production facilities in the Netherlands. We develop and manufacture small molecule APIs in a cost-effective, robust, and compliant way. We have our own portfolio of generic APIs, but we also operate as a CDMO for a wide range of customers. We are a stable family-owned business and with nearly 50 years of experience we have a long history of regulatory compliance and a strong reputation for reliability and quality.
Ofichem Company Banner

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothASolution Pharmaceuticals: Your Partner for cGMP Development & Manufacturing Services – Supplying APIs, FDFs, and Specialty Molecules.

Flag India
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Palmitoylethanolamide

About the Company : Since 2010, our dedication to our clientele has been unwavering in addressing pharmaceutical hurdles, regardless of scale. We prioritize integrity, responsiveness, and punctuality,...

Since 2010, our dedication to our clientele has been unwavering in addressing pharmaceutical hurdles, regardless of scale. We prioritize integrity, responsiveness, and punctuality, embedding our values into every endeavor. Our aim is to cultivate mutually beneficial relationships with customers, suppliers, and ourselves, fostering sustainable growth. Empowered by visionary leadership and a quality-driven team, ASolution is steadfast in providing innovative solutions to challenges such as Process Development, Optimization, Drug Product and Substance Manufacturing, and more.
ASolution Pharmaceuticals

03

Allastir

India
The Pharmacy Technology
Not Confirmed
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Allastir

India
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The Pharmacy Technology
Not Confirmed

Palmitoylethanolamide

About the Company : Allastir instituted the services in 2010 with a motive to cater the pharmaceutical industry with niche API's. In Allastir we strongly believe in team work and customer satisfaction...

Allastir instituted the services in 2010 with a motive to cater the pharmaceutical industry with niche API's. In Allastir we strongly believe in team work and customer satisfaction. Allastir is backed by the strong R&D team who are passionate about what they do. We manufacture niche API's with high quality which are suitable for formulations like tablets, capsules, soft gelatins and oral liquids.To be the larder to develop innovative niche molecule to the health care industry for the betterment of human life.Our Vision is to be the Number ONE company in Health care Industry in the World.
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04

TBD Pharmatech

Estonia
The Pharmacy Technology
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TBD Pharmatech

Estonia
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Palmitoylethanolamide

About the Company : TBD Pharmatech (formerly TBD-Biodiscovery) specializes in Active Pharmaceutical Ingredients (API), advanced intermediates, and the development and production of fine chemicals. It ...

TBD Pharmatech (formerly TBD-Biodiscovery) specializes in Active Pharmaceutical Ingredients (API), advanced intermediates, and the development and production of fine chemicals. It is a Contract Development and Manufacturing Organisation (CDMO) with 16 years of experience in the market. It combines GMP-compliant production with strong R&D and extensive experience in the validation process—something that makes TBD the perfect partner to develop your ideas.
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05

The Pharmacy Technology
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Palmidrol

About the Company : Further Pharmaceutical (www.further-pharm.com) is an innovation-driven and service-oriented biopharmaceutical company with global operations that develops and manufactures specialt...

Further Pharmaceutical (www.further-pharm.com) is an innovation-driven and service-oriented biopharmaceutical company with global operations that develops and manufactures specialty and generic drugs, pharmaceutical intermediates and APIs. We remain focused on advancing innovative drug formulations and progressing therapeutic products to improve human health and quality of life while reducing the medical expenses.
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Palmidrol

About the Company : Zhejiang Bamboo Pharmaceuticals is a new, innovative, green, high-grade pharmaceutical intermediate, API and oral solid formulation pharmaceutical manufacturer which was establishe...

Zhejiang Bamboo Pharmaceuticals is a new, innovative, green, high-grade pharmaceutical intermediate, API and oral solid formulation pharmaceutical manufacturer which was established in 2020. The company is positioned as a modern and regulatory pharmaceutical company with API and formulation drug. The formulation drug are mainly sold to the domestic market, and the goal is to become one of the largest supplier of Chinese "4 + 7" volume procurement in China.
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API Reference Price

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13-Apr-2022
24-May-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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