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1. R-667
2. Rg-667
3. Ro-3300074
1. 410528-02-8
2. Rg-667
3. Ro-3300074
4. Sohonos
5. Clm-001
6. Ipn60120
7. R-667
8. R 667
9. Ipn-60120
10. Ro 3300074
11. Ro3300074
12. 4-((1e)-2-(5,5,8,8-tetramethyl-3-(1h-pyrazol-1-ylmethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl)benzoic Acid
13. 4-[(e)-2-[5,5,8,8-tetramethyl-3-(pyrazol-1-ylmethyl)-6,7-dihydronaphthalen-2-yl]ethenyl]benzoic Acid
14. 28k6i5m16g
15. (e)-4-(2-(3-((1h-pyrazol-1-yl)methyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic Acid
16. Benzoic Acid, 4-((1e)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(1h-pyrazol-1-ylmethyl)-2-naphthalenyl)ethenyl)-
17. Palovarotene [usan]
18. Palovarotene [usan:inn]
19. Unii-28k6i5m16g
20. Palovarotene(r 667)
21. Palovarotene (usan/inn)
22. Palovarotene [inn]
23. Palovarotene [jan]
24. Palovarotene [who-dd]
25. Gtpl8276
26. Schembl4658931
27. Chembl2105648
28. Chebi:188559
29. Dtxsid301025696
30. Bcp16664
31. Ex-a3101
32. Who 9025
33. Zb1580
34. Zinc38467831
35. Cs-2031
36. Db12320
37. Ac-36331
38. Hy-14799
39. R667
40. R 667;ro 3300074
41. D09365
42. 528p028
43. A914214
44. Q15708269
45. 4-[(e)-2-(5,5,8,8-tetramethyl-3-pyrazol-1-ylmethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)vinyl]benzoic Acid
Molecular Weight | 414.5 g/mol |
---|---|
Molecular Formula | C27H30N2O2 |
XLogP3 | 6.8 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 5 |
Exact Mass | 414.230728204 g/mol |
Monoisotopic Mass | 414.230728204 g/mol |
Topological Polar Surface Area | 55.1 Ų |
Heavy Atom Count | 31 |
Formal Charge | 0 |
Complexity | 662 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 1 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in emphysema.
Treatment of multiple osteochondromas
Treatment of fibrodysplasia ossificans progressiva
R667 is an orally active, gamma selective retinoid agonist that shows promise as a treatment for emhysema.
M - Musculo-skeletal system
M09 - Other drugs for disorders of the musculo-skeletal system
M09A - Other drugs for disorders of the musculo-skeletal system
M09AX - Other drugs for disorders of the musculo-skeletal system
M09AX11 - Palovarotene
Gamma-selective retinoic acid receptor agonist.