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Synopsis

ACTIVE PHARMA INGREDIENTS

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NDC API

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Chemistry

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Also known as: 449811-01-2, Ro 4402257, R1503, Ro4402257, Ro-4402257, Chembl1090089
Molecular Formula
C19H20F2N4O4
Molecular Weight
406.4  g/mol
InChI Key
JYYLVUFNAHSSFE-UHFFFAOYSA-N
FDA UNII
8S2C9V11K4

Pamapimod
1 2D Structure

Pamapimod

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one
2.1.2 InChI
InChI=1S/C19H20F2N4O4/c1-25-17-11(10-22-19(24-17)23-13(4-6-26)5-7-27)8-16(18(25)28)29-15-3-2-12(20)9-14(15)21/h2-3,8-10,13,26-27H,4-7H2,1H3,(H,22,23,24)
2.1.3 InChI Key
JYYLVUFNAHSSFE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO
2.2 Other Identifiers
2.2.1 UNII
8S2C9V11K4
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 449811-01-2

2. Ro 4402257

3. R1503

4. Ro4402257

5. Ro-4402257

6. Chembl1090089

7. Chebi:90685

8. R-1503

9. 8s2c9v11k4

10. Pamapimod (r-1503, Ro4402257)

11. 6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one

12. 6-(2,4-difluorophenoxy)-2-[[3-hydroxy-1-(2-hydroxyethyl)propyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one

13. 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one

14. Pamapimod [usan]

15. Pamapimod [usan:inn]

16. Unii-8s2c9v11k4

17. 6-(2,4-difluorophenoxy)-2-((1,5-dihydroxypentan-3-yl)amino)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one

18. 6-(2,4-difluorophenoxy)-2-((3-hydroxy-1-(2-hydroxyethyl)propyl)amino)-8-methylpyrido(2,3-d)pyrimidin-7(8h)-one

19. 6-(2,4-difluorophenoxy)-2-[(1,5-dihydroxypentan-3-yl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one

20. Pamapimodr-1503

21. Pamapimod [inn]

22. Pamapimod (inn/usan)

23. R 1503

24. Pamapimod [who-dd]

25. Gtpl9915

26. Schembl3636701

27. Dtxsid90963312

28. Bcp17491

29. Ex-a1084

30. Bdbm50314070

31. Mfcd25976551

32. S8125

33. Zinc30691792

34. Ccg-268715

35. Cs-5965

36. Compound 2b [pmid: 21375264]

37. Ac-33182

38. As-56094

39. Hy-10405

40. Ft-0673504

41. D08963

42. Q27162644

43. 6-(2,4-difluorophenoxy)-2-[(1,5-dihydroxypentan-3-yl)amino]-8-methyl-7h,8h-pyrido[2,3-d]pyrimidin-7-one

44. 6-(2,4-difluorophenoxy)-2-[(1,5-dihydroxypentan-3-yl)imino]-8-methyl-2,8-dihydropyrido[2,3-d]pyrimidin-7(3h)-one

45. Flw

46. Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-(2,4-difluorophenoxy)-2-((3-hydroxy-1-(2-hydroxyethyl)propyl)amino)-8-methyl-

2.4 Create Date
2007-07-23
3 Chemical and Physical Properties
Molecular Weight 406.4 g/mol
Molecular Formula C19H20F2N4O4
XLogP32.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Exact Mass406.14526146 g/mol
Monoisotopic Mass406.14526146 g/mol
Topological Polar Surface Area108 Ų
Heavy Atom Count29
Formal Charge0
Complexity591
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 449811-01-2 / Pamapimod API manufacturers, exporters & distributors?

Pamapimod manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Pamapimod API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Pamapimod manufacturer or Pamapimod supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Pamapimod manufacturer or Pamapimod supplier.

PharmaCompass also assists you with knowing the Pamapimod API Price utilized in the formulation of products. Pamapimod API Price is not always fixed or binding as the Pamapimod Price is obtained through a variety of data sources. The Pamapimod Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Pamapimod

Synonyms

449811-01-2, Ro 4402257, R1503, Ro4402257, Ro-4402257, Chembl1090089

Cas Number

449811-01-2

Unique Ingredient Identifier (UNII)

8S2C9V11K4

Pamapimod Manufacturers

A Pamapimod manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pamapimod, including repackagers and relabelers. The FDA regulates Pamapimod manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pamapimod API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Pamapimod Suppliers

A Pamapimod supplier is an individual or a company that provides Pamapimod active pharmaceutical ingredient (API) or Pamapimod finished formulations upon request. The Pamapimod suppliers may include Pamapimod API manufacturers, exporters, distributors and traders.

Pamapimod GMP

Pamapimod Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pamapimod GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pamapimod GMP manufacturer or Pamapimod GMP API supplier for your needs.

Pamapimod CoA

A Pamapimod CoA (Certificate of Analysis) is a formal document that attests to Pamapimod's compliance with Pamapimod specifications and serves as a tool for batch-level quality control.

Pamapimod CoA mostly includes findings from lab analyses of a specific batch. For each Pamapimod CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pamapimod may be tested according to a variety of international standards, such as European Pharmacopoeia (Pamapimod EP), Pamapimod JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pamapimod USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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