Find Pantethine manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

CEP/COS

CEP/COS Certifications

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDA Orange Book

FDA (Orange Book)

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

143 RELATED EXCIPIENT COMPANIES

241EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: D-pantethine, 16816-67-4, Pantomin, Pantetina, Pantosin, Lbf disulfide
Molecular Formula
C22H42N4O8S2
Molecular Weight
554.7  g/mol
InChI Key
DJWYOLJPSHDSAL-ROUUACIJSA-N
FDA UNII
7K81IL792L

Pantethine
Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine. It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including fatty acid oxidation, carbohydrate metabolism, pyruvate degradation, and amino acid catabolism. Pantethine is available as a dietary supplement for lowering blood cholesterol and triglycerides.
1 2D Structure

Pantethine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R)-N-[3-[2-[2-[3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
2.1.2 InChI
InChI=1S/C22H42N4O8S2/c1-21(2,13-27)17(31)19(33)25-7-5-15(29)23-9-11-35-36-12-10-24-16(30)6-8-26-20(34)18(32)22(3,4)14-28/h17-18,27-28,31-32H,5-14H2,1-4H3,(H,23,29)(H,24,30)(H,25,33)(H,26,34)/t17-,18-/m0/s1
2.1.3 InChI Key
DJWYOLJPSHDSAL-ROUUACIJSA-N
2.1.4 Canonical SMILES
CC(C)(CO)C(C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)C(C(C)(C)CO)O)O
2.1.5 Isomeric SMILES
CC(C)(CO)[C@H](C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@@H](C(C)(C)CO)O)O
2.2 Other Identifiers
2.2.1 UNII
7K81IL792L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Lipodel

2. Liponet

3. Obliterol

4. Pantethine, (d)-(+)-isomer

5. Pantethine, 14c-labeled Cpd

2.3.2 Depositor-Supplied Synonyms

1. D-pantethine

2. 16816-67-4

3. Pantomin

4. Pantetina

5. Pantosin

6. Lbf Disulfide

7. Pantethine [jan]

8. Bis(pantothenamidoethyl) Disulfide

9. D-pantethine Syrup

10. D-bis(n-pantothenyl-beta-aminoethyl) Disulfide

11. (2r)-n-[3-[2-[2-[3-[[(2r)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide

12. D-bis(n-pantothenyl-2-aminoethyl)-disulfide

13. Lipodel

14. Chebi:31959

15. 7k81il792l

16. Nsc-759269

17. (r-(r*,r*))-n,n'-(dithiobis(ethyleneimino(3-oxopropane-3,1-diyl)))bis(2,4-dihydroxy-3,3-dimethylbutyramide)

18. 644967-47-5

19. Pantosin (tn)

20. (2r)-n-[2-({2-[(2-{3-[(2r)-2,4-dihydroxy-3,3-dimethylbutanamido]propanamido}ethyl)disulfanyl]ethyl}carbamoyl)ethyl]-2,4-dihydroxy-3,3-dimethylbutanamide

21. (2r,2'r)-n,n'-(((disulfanediylbis(ethane-2,1-diyl))bis(azanediyl))bis(3-oxopropane-3,1-diyl))bis(2,4-dihydroxy-3,3-dimethylbutanamide)

22. Butanamide, N,n'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethyl-, (2r,2'r)-

23. Butanamide, N,n'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethyl-, (2r,2'r)-rel-

24. Einecs 240-842-8

25. Bis-pantethine

26. Unii-7k81il792l

27. D-pantomin

28. Pantethine Liquid

29. Ncgc00181028-01

30. Pantethine 50 G

31. Pantethine 80%

32. Butanamide, N,n'-(dithiobis(2,1-ethanediylimino(3-oxo-3,1-propanediyl)))bis(2,4-dihydroxy-3,3-dimethyl-, (2r,2'r)-

33. Pantethine [mi]

34. Pantethine 50% Granule

35. Pantethine [inci]

36. Pantethine(50% Granula)

37. Pantethine [mart.]

38. D-pantethine Hydrate, Syrup

39. Pantethine [who-dd]

40. Mls004734407

41. Schembl1650348

42. Chembl2104786

43. Dtxsid9046815

44. D-pantethine, Analytical Standard

45. Hy-b1028

46. Zinc3874604

47. Mfcd07357234

48. S5220

49. Akos015898599

50. Ccg-270026

51. Cs-4546

52. Db11190

53. Gs-6223

54. Nsc 759269

55. Ncgc00181028-02

56. Butanamide, N,n'-(dithiobis(2,1-ethanediylimino(3-oxo-3,1-propanediyl)))bis(2- ,4-dihydroxy-3,3-dimethyl-

57. Butyramide, N,n'-(dithiobis(ethyleneiminocarbonylethylene))bis(2,4-dihydroxy-3,3-dimethyl-, D-(+)-

58. N,n'-(dithiobis(2,1-ethanediylimino(3-oxo-3,1-propanediyl)))bis(2- ,4-dihydroxy-3,3-dimethylbutanamide

59. Smr001825140

60. H10620

61. Q228762

62. D-bis(n-pantothenyl-2-aminoethyl)-disulphide

63. J-010433

64. (2r)-n-[3-[2-[2-[3-[[(2r)-2,4-dihydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxo-propyl]-2,4-dihydroxy-3,3-dimethyl-butanamide

65. (2r,2'r)-n,n'-{disulfanediylbis[ethane-2,1-diylimino(3-oxopropane-3,1-diyl)]}bis(2,4-dihydroxy-3,3-dimethylbutanamide)

66. N,n'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethylbutanamide]

67. N-[2-[2-[2-[3-[(2,4-dihydroxy-3,3-dimethyl-butanoyl)amino]propanoylamino]ethyldisulfanyl]ethylcarbamoyl]ethyl]-2,4-dihydroxy-3,3-dimethyl-butanamide

2.4 Create Date
2005-08-01
3 Chemical and Physical Properties
Molecular Weight 554.7 g/mol
Molecular Formula C22H42N4O8S2
XLogP3-2.2
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count10
Rotatable Bond Count19
Exact Mass554.24440666 g/mol
Monoisotopic Mass554.24440666 g/mol
Topological Polar Surface Area248 Ų
Heavy Atom Count36
Formal Charge0
Complexity652
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

A - Alimentary tract and metabolism

A11 - Vitamins

A11H - Other plain vitamin preparations

A11HA - Other plain vitamin preparations

A11HA32 - Pantethine


Europe

read-more
read-more

01

PHARMAFAR Srl

Country
DDL Conference
Not Confirmed
arrow

PHARMAFAR Srl

Country
arrow
DDL Conference
Not Confirmed

Pantethine

Brand Name : Pantethine

Dosage Form :

Dosage Strength : 30 Cps 300 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Coating Systems & Additives

read-more
read-more

Controlled & Modified Release

read-more
read-more

Fillers, Diluents & Binders

read-more
read-more

Thickeners and Stabilizers

read-more
read-more

Lubricants & Glidants

read-more
read-more

Direct Compression

read-more
read-more

Film Formers & Plasticizers

read-more
read-more

Granulation

read-more
read-more

Topical

read-more
read-more

Co-Processed Excipients

read-more
read-more

Disintegrants & Superdisintegrants

read-more
read-more

Taste Masking

read-more
read-more

Empty Capsules

read-more
read-more

API Stability Enhancers

read-more
read-more

Solubilizers

read-more
read-more

Parenteral

read-more
read-more

Vegetarian Capsules

read-more
read-more

Coloring Agents

read-more
read-more

Emulsifying Agents

read-more
read-more

Chewable & Orodispersible Aids

read-more
read-more

Rheology Modifiers

read-more
read-more

Global Sales Information

Do you need Business Intel? Ask us

Market Place

Do you need sourcing support? Ask us

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty