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Chemistry

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Also known as: 147-24-0, Diphenhydramine hcl, Dimedrol, Allergival, Carphenamine, Bendylate
Molecular Formula
C17H22ClNO
Molecular Weight
291.8  g/mol
InChI Key
PCHPORCSPXIHLZ-UHFFFAOYSA-N
FDA UNII
TC2D6JAD40

Diphenhydramine Hydrochloride
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
1 2D Structure

Diphenhydramine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-benzhydryloxy-N,N-dimethylethanamine;hydrochloride
2.1.2 InChI
InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
2.1.3 InChI Key
PCHPORCSPXIHLZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
2.2 Other Identifiers
2.2.1 UNII
TC2D6JAD40
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-diphenylmethoxy-n,n-dimethylethylamine

2. Allerdryl

3. Benadryl

4. Benhydramin

5. Benylin

6. Benzhydramine

7. Citrate, Diphenhydramine

8. Dimedrol

9. Diphenhydramine

10. Diphenhydramine Citrate

11. Diphenhydramine Citrate (1:1)

12. Diphenylhydramin

13. Diphenylhydramine

14. Dormin

15. Hydrochloride, Diphenhydramine

2.3.2 Depositor-Supplied Synonyms

1. 147-24-0

2. Diphenhydramine Hcl

3. Dimedrol

4. Allergival

5. Carphenamine

6. Bendylate

7. Carphenex

8. Cathejell

9. Denydryl

10. Diphamine

11. Eldadryl

12. Fenylhist

13. Noctomin

14. Ambenyl

15. Felben

16. Prodryl

17. Bena

18. Diphenhydramine.hcl

19. Diphenhydramine (hydrochloride)

20. Allergan

21. Benylin

22. Dibenil

23. Hydramine

24. Paradryl

25. Restamin

26. Silphen

27. Vicks Formula 44

28. Beldin

29. Benzhydramine Hydrochloride

30. Diphen

31. Belix

32. Dobacen Hydrochloride

33. Dimedrol Hydrochloride

34. Benzantin Hydrochloride

35. Difenhydramine Hydrochloride

36. 2-(benzhydryloxy)-n,n-dimethylethanamine Hydrochloride

37. Benzantin

38. Dimedrolum

39. Diphenylhydramine Hydrochloride

40. Nci-c56075

41. Ethanamine, 2-(diphenylmethoxy)-n,n-dimethyl-, Hydrochloride

42. 2-(benzhydryloxy)-n,n-dimethylethylamine Hydrochloride

43. Mfcd00012479

44. Diphenhydramine Hcl (benadryl)

45. 2-(diphenylmethoxy)-n,n-dimethylethylamine Hydrochloride

46. N-(2-diphenylmethoxyethyl)-n,n-dimethylamine Hydrochloride

47. Nsc-33299

48. Tc2d6jad40

49. Mls000028428

50. 2-benzhydryloxy-n,n-dimethylethanamine;hydrochloride

51. 147-24-0 (hcl)

52. Sedopretten

53. Halbmond

54. Histacyl

55. Smr000058353

56. Wehydryl

57. Resmin

58. Vena

59. Dsstox_cid_537

60. Sekundal-d

61. 2-diphenylmethoxy-n,n-dimethylethylamine Hydrochloride

62. Beta-dimethylaminoethyl Benzhydryl Ether Hydrochloride

63. Dsstox_rid_75646

64. Dsstox_gsid_20537

65. Alpha-hydroxydiphenylmethane-beta-dimethylaminoethyl Ether Hydrochloride

66. Diphenhydramine Hydrochloride 100 Microg/ml In Acetonitrile

67. Dipjemhist

68. 2-[(diphenylmethyl)oxy]-n,n-dimethylethanamine Hydrochloride

69. Banophen

70. Asdrin

71. Benadryl Preservative Free

72. Chebi:4637

73. Sk-diphenhydramine

74. Sleep-eze-3

75. Benadryl Hydrochloride

76. Ccris 2383

77. Sr-01000003069

78. Ncgc00015335-09

79. Cas-147-24-0

80. Einecs 205-687-2

81. Nsc 33299

82. Unii-tc2d6jad40

83. Tylenol Pm Tablets/caplets

84. Tylenol Cold Night Time Liquid

85. Antitussive Agents

86. Benadryl (tn)

87. Prestwick_177

88. Bayer Select Night Time Pain Relief

89. Component Of Caladryl

90. Benadril Hydrochloride

91. Benzhydrol, Beta-dimethylaminoethyl Ether Hydrochloride

92. Dimedrol-hydrochloride

93. Difenidramina Cloridrato

94. Cpd000058353

95. Opera_id_152

96. Component Of Bena-fedrin

97. Dimethylamine Benzhydryl Ester Hydrochloride

98. Diphenhydramine Hydrochloride [usp:ban:jan]

99. Diphenhydramine Hydrochloride Preservative Free

100. Cloridrato De Difenidramina

101. Diphenydramine Hydrochloride

102. Chembl1620

103. Regid_for_cid_8980

104. Schembl17071

105. Mls000758216

106. Mls001148114

107. Mls001423951

108. Mls002222180

109. Spectrum1500256

110. Dtxsid4020537

111. Hy-b0303a

112. Diphenhydramine Hydrochloride,(s)

113. Diphenhydramine Hcl [inci]

114. Hms1568m11

115. Hms1920i06

116. Pharmakon1600-01500256

117. Bcp13546

118. Nsc33299

119. Tox21_112991

120. Tox21_201472

121. Tox21_300611

122. Tox21_500377

123. Ccg-39755

124. Nsc756729

125. S1866

126. Akos005287308

127. Ac-3449

128. Lp00377

129. Nc00060

130. Nsc-756729

131. Ncgc00024414-05

132. Ncgc00093809-01

133. Ncgc00093809-02

134. Ncgc00093809-03

135. Ncgc00093809-04

136. Ncgc00093809-05

137. Ncgc00254264-01

138. Ncgc00259023-01

139. Ncgc00261062-01

140. As-12088

141. Diphenhydramine Hydrochloride (jp17/usp)

142. Diphenhydramine Hydrochloride [mi]

143. Sy010546

144. 2-benzhydryloxy-n,n-dimethylethanamine Hcl

145. Diphenhydramine Hydrochloride [jan]

146. Wln: 1n1 & 2oyr & R & Gh

147. 4-acetoxy-3,5-dimethoxybenzoicacid

148. D0423

149. Diphenhydramine Hydrochloride [mart.]

150. Diphenhydramine Hydrochloride [vandf]

151. Eu-0100377

152. Ft-0652576

153. Sw198731-2

154. Diphenhydramine Hydrochloride [usp-rs]

155. Diphenhydramine Hydrochloride [who-dd]

156. Diphenhydramine Hydrochloride, >=98% (hplc)

157. C07784

158. D 3630

159. D00669

160. Diphenhydramine Hydrochloride, Analytical Standard

161. N-(2-diphenylmethoxyethyl)-n,n-dimethylamine Hcl

162. Diphenhydramine Hydrochloride [ep Impurity]

163. Diphenhydramine Hydrochloride [orange Book]

164. Diphenhydramine Hydrochloride [ep Monograph]

165. Diphenhydramine Hydrochloride [usp Monograph]

166. Q-201003

167. Sr-01000003069-2

168. 2-(benzhydryloxy)-n,n-dimethylethanaminehydrochloride

169. 2-benzhydryloxy-n,n-dimethylethanamine;hydron;chloride

170. 2-diphenylmethoxy-n,n-dimethylethanamine Hydrochloride

171. Q26841258

172. Sr-01000003069-10

173. .beta.-dimethylaminoethyl Benzhydryl Ether Hydrochloride

174. 2-(benzhydryloxy)-n,n-dimethylethan-1-amine Hydrochloride

175. Ethylamine,n-dimethyl-2-(diphenylmethoxy)-, Hydrochloride

176. Diphenhydramine Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

177. Ethanamine, 2-(diphenylmethoxy)-n,n-dimethyl-, Hydrochloride (1:1)

178. .alpha.-hydroxydiphenylmethane-.beta.-dimethylaminoethyl Ether Hydrochloride

179. Diphenhydramine Hydrochloride, British Pharmacopoeia (bp) Reference Standard

180. Diphenhydramine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

181. Diphenhydramine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

182. 8052-21-9

183. Diphenhydramine Hydrochloride Solution, 1.0 Mg/ml In Methanol (as Free Base), Ampule Of 1 Ml, Certified Reference Material

184. Diphenhydramine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 291.8 g/mol
Molecular Formula C17H22ClNO
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count6
Exact Mass291.1389920 g/mol
Monoisotopic Mass291.1389920 g/mol
Topological Polar Surface Area12.5 Ų
Heavy Atom Count20
Formal Charge0
Complexity211
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameDiphenhydramine hydrochloride
Drug LabelDiphenhydramine Hydrochloride is an antihistamine drug having the chemical name 2-(diphenylmethoxy)-N, N-dimethylethylamine hydrochloride. It occurs as a white, odorless crystalline powder and is freely soluble in water and alcohol. The structural fo...
Active IngredientDiphenhydramine hydrochloride
Dosage FormElixir; Injectable; Capsule
RouteInjection; Oral
Strength50mg/ml; 50mg; 12.5mg/5ml
Market StatusPrescription
CompanyHospira; Hikma Maple; Mylan Institutional; Pharm Assoc; App Pharms; Barr

2 of 4  
Drug NameDiphenhydramine hydrochloride preservative free
Active IngredientDiphenhydramine hydrochloride
Dosage FormInjectable
RouteInjection
Strength50mg/ml
Market StatusPrescription
CompanyBd Rx

3 of 4  
Drug NameDiphenhydramine hydrochloride
Drug LabelDiphenhydramine Hydrochloride is an antihistamine drug having the chemical name 2-(diphenylmethoxy)-N, N-dimethylethylamine hydrochloride. It occurs as a white, odorless crystalline powder and is freely soluble in water and alcohol. The structural fo...
Active IngredientDiphenhydramine hydrochloride
Dosage FormElixir; Injectable; Capsule
RouteInjection; Oral
Strength50mg/ml; 50mg; 12.5mg/5ml
Market StatusPrescription
CompanyHospira; Hikma Maple; Mylan Institutional; Pharm Assoc; App Pharms; Barr

4 of 4  
Drug NameDiphenhydramine hydrochloride preservative free
Active IngredientDiphenhydramine hydrochloride
Dosage FormInjectable
RouteInjection
Strength50mg/ml
Market StatusPrescription
CompanyBd Rx

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anesthetics, Local

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)


Anti-Allergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)


Hypnotics and Sedatives

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)


Antiemetics

Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)


Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)


Sleep Aids, Pharmaceutical

Drugs used to induce SLEEP, prevent SLEEPLESSNESS, or treat SLEEP INITIATION AND MAINTENANCE DISORDERS. (See all compounds classified as Sleep Aids, Pharmaceutical.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Histamine-1 Receptor Antagonist [EPC]; Histamine H1 Receptor Antagonists [MoA]

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Knoll Ag Ludwigshafen

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LIFESCIENCE","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"CONSIGNEE","customerCountry":"INDONESIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"18.5","totalValueFC":"9159","currency":"USD","unitRateINR":1539.2,"date":"30-Oct-2024","totalValueINR":"769600","totalValueInUsd":"9159","indian_port":"JNPT","hs_no":"29420090","bill_no":"5277733","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"207\/208,UDYOG BHAVAN,SONAWALA ROAD,, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"DIPHENHYDRAMINE HYDROCHLORIDE","year":"2021","qtr":"Q2","strtotime":1619202600,"product":"(REIMPORT AND REEXPORT UNDER SECTION 69) DIPHENHYDRAMINE HYDROCHLORIDE (RETURNED GOODS DUE TO ORDER CANCELLATION)","address":"201 SWASTIK PLAZA, SUBHASH NAGAR,\\r\\nPOKHARAN RD NO 2,","city":"THANE WEST","supplier":"HENAN JUNSHUAI BIOTECHNOLOGY ","supplierCountry":"INDIA","foreign_port":"","customer":"ZEAL MEDIPHARMA EXPORT ","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"12.5","totalValueFC":"25571.2","currency":"USD","unitRateINR":"951.9","date":"24-Apr-2021","totalValueINR":"1903750","totalValueInUsd":"25571.2","indian_port":"JNPT","hs_no":"29420090","bill_no":"3690583","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"201 SWASTIK PLAZA, SUBHASH NAGAR,\\r\\nPOKHARAN RD NO 2,"},{"dataSource":"API Import","activeIngredients":"DIPHENHYDRAMINE HYDROCHLORIDE","year":"2021","qtr":"Q2","strtotime":1619289000,"product":"DIPHENHYDRAMINE HYDROCHLORIDE USP LOT: 8104369 DRUM LOCK: 0170695 PART NO. 93717","address":"PLOT NO.N- 39 AND PLOT NO. N- 39\/1, ADDITIONAL AMBERNATH MIDC, ANAND","city":"NAGAR,AMBERNATH(EAST) THANEH","supplier":"PERRIGO COMPANY PLC","supplierCountry":"UNITED STATES","foreign_port":"","customer":"PERRIGO COMPANY PLC","customerCountry":"INDIA","quantity":"17.00","actualQuantity":"17","unit":"KGS","unitRateFc":"84","totalValueFC":"1460.6","currency":"USD","unitRateINR":"6396.6","date":"25-Apr-2021","totalValueINR":"108742.2","totalValueInUsd":"1460.6","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3705755","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"PLOT NO.N- 39 AND PLOT NO. N- 39\/1, ADDITIONAL AMBERNATH MIDC, ANAND"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1659292200,"product":"DIPHENHYDRAMINE HYDROCHLORIDE (850 G)","address":"SHANKAR TOWERS PLOT NO. A30,A.I.E BALANAGAR HYDERABAD","city":"HYDERABAD,TELANGANA","supplier":"RECORDATI","supplierCountry":"ITALY","foreign_port":"NA","customer":"ANTHEA PHARMA PVT LTD","customerCountry":"INDIA","quantity":"0.85","actualQuantity":"0.85","unit":"KGS","unitRateFc":"2352.9","totalValueFC":"2034.8","currency":"USD","unitRateINR":"190470.6","date":"01-Aug-2022","totalValueINR":"161900","totalValueInUsd":"2034.8","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"9822078","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SHANKAR TOWERS PLOT NO. A30,A.I.E BALANAGAR HYDERABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1682533800,"product":"DIPHENHYDRAMINE HCL -USP","address":"11TH FLR.GRANDEUR,OPP.GUNDECHA,SYM PHONY, VEERA DESAI RD.EXTENSION","city":"MUMBAI SUBURBAN,MAHARASHTRA","supplier":"SHANGHAI DONGYUE PHARMACEUTICAL CO.","supplierCountry":"CHINA","foreign_port":"NA","customer":"MARKSANS PHARMA","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"17","totalValueFC":"742.9","currency":"USD","unitRateINR":"2435.3","date":"27-Apr-2023","totalValueINR":"60882.43","totalValueInUsd":"742.9","indian_port":"BOMBAY AIR","hs_no":"29332100","bill_no":"5706344","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"11TH FLR.GRANDEUR,OPP.GUNDECHA,SYM PHONY, VEERA DESAI RD.EXTENSION"}]
04-Jan-2021
30-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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FDA Orange Book

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01

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 10MG/ML

Approval Date : 1982-01-01

Application Number : 80873

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

Dr Reddy Company Banner

02

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 50MG/ML

Approval Date : 1982-01-01

Application Number : 80873

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

Dr Reddy Company Banner

03

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE PRESERVATIVE FREE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 50MG/ML

Approval Date : 1982-01-01

Application Number : 80873

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

Dr Reddy Company Banner

04

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DIPHENHYDRAMINE HYDROCHLORIDE; IBUPROFEN

Brand Name : IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 25MG;EQ 200MG FREE ACID AND POTASSIUM SALT

Approval Date : 2012-03-05

Application Number : 200888

RX/OTC/DISCN : OTC

RLD : No

TE Code :

Strides Pharma Science

05

GRANULES

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothGranules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DIPHENHYDRAMINE HYDROCHLORIDE; NAPROXEN SODIUM

Brand Name : NAPROXEN SODIUM AND DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : TABLET;ORAL

Dosage Strength : 25MG;220MG

Approval Date : 2020-09-24

Application Number : 213663

RX/OTC/DISCN : OTC

RLD : No

TE Code :

Granules India

06

WATSON LABS

Ireland
euroPLX 86 Munich
Not Confirmed
arrow

WATSON LABS

Ireland
arrow
euroPLX 86 Munich
Not Confirmed

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 25MG

Approval Date : 1982-01-01

Application Number : 83797

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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07

HOSPIRA

U.S.A
euroPLX 86 Munich
Not Confirmed
arrow

HOSPIRA

U.S.A
arrow
euroPLX 86 Munich
Not Confirmed

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 50MG/ML

Approval Date : 1998-11-20

Application Number : 40140

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

08

PVT FORM

Country
euroPLX 86 Munich
Not Confirmed
arrow

PVT FORM

Country
arrow
euroPLX 86 Munich
Not Confirmed

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 25MG

Approval Date : 1982-01-01

Application Number : 83027

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

09

PVT FORM

Country
euroPLX 86 Munich
Not Confirmed
arrow

PVT FORM

Country
arrow
euroPLX 86 Munich
Not Confirmed

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : ELIXIR;ORAL

Dosage Strength : 12.5MG/5ML

Approval Date : 1982-01-01

Application Number : 85287

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

blank

10

euroPLX 86 Munich
Not Confirmed
arrow
arrow
euroPLX 86 Munich
Not Confirmed

DIPHENHYDRAMINE HYDROCHLORIDE

Brand Name : DIPHENHYDRAMINE HYDROCHLORIDE

Dosage Form : CAPSULE;ORAL

Dosage Strength : 25MG

Approval Date : 1987-01-02

Application Number : 89488

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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Europe

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01

Gebro Pharma AG

Austria
American Pharma Summit
Not Confirmed
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Gebro Pharma AG

Austria
arrow
American Pharma Summit
Not Confirmed

Dihydrocodeini hydrochloridum; Diphenhydramini hydrochloridum

Brand Name : Makatussin Comp

Dosage Form : Sirup

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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02

American Pharma Summit
Not Confirmed
arrow
arrow
American Pharma Summit
Not Confirmed

Diphenhydramine Hydrochloride

Brand Name : Diphenhydramine Hydrochloride

Dosage Form :

Dosage Strength : 20 Cpr 25 Mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

Meda AB

Country
American Pharma Summit
Not Confirmed
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Meda AB

Country
arrow
American Pharma Summit
Not Confirmed

diphenhydramine hydrochloride

Brand Name : Desentol

Dosage Form : ORAL SOLUTION

Dosage Strength : -

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

blank

04

UNIFARM SpA

Country
American Pharma Summit
Not Confirmed
arrow

UNIFARM SpA

Country
arrow
American Pharma Summit
Not Confirmed

Diphenhydramine Hydrochloride

Brand Name : Aliserin

Dosage Form :

Dosage Strength : 20 Bust Grat Eff 25 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Listed Dossiers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Diphenhydramine Hydrochloride; Ibuprofen

Brand Name :

Dosage Form : Capsule

Dosage Strength : 200MG; 25MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Strides Pharma Science

01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothStrides Pharma Science: Pioneering IP-driven formulations for niche finished dosage forms.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Diphenhydramine Hydrochloride; Ibuprofen

Dosage : Capsule

Dosage Strength : 200MG; 25MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

Strides Pharma Science

02

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Aminophylline; Diphenhydramine Hydrochloride; Ammonium Chloride; Menthol

Brand Name : Cofllin (Sugar Free)

Dosage Form : SYRUP

Dosage Strength : 32MG; 8MG; 30MG; 5MG

Packaging : 120ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Pakistan

blank

02

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Aminophylline; Diphenhydramine Hydrochloride; Ammonium Chloride; Menthol

Dosage : SYRUP

Dosage Strength : 32MG; 8MG; 30MG; 5MG

Brand Name : Cofllin (Sugar Free)

Approval Date :

Application Number :

Registration Country : Pakistan

blank

03

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Aminophylline; Diphenhydramine Hydrochloride; Ammonium Chloride; Menthol

Brand Name : Amwarm

Dosage Form : SYRUP

Dosage Strength : 32MG; 8MG; 30MG; 5MG

Packaging : as per requirement

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Pakistan

blank

03

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Aminophylline; Diphenhydramine Hydrochloride; Ammonium Chloride; Menthol

Dosage : SYRUP

Dosage Strength : 32MG; 8MG; 30MG; 5MG

Brand Name : Amwarm

Approval Date :

Application Number :

Registration Country : Pakistan

blank

04

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Dextromethorphan; Diphenhydramine Hydrochloride

Brand Name : Biollin-Dm

Dosage Form : SYRUP

Dosage Strength : 6.25MG; 5MG

Packaging : 120ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Pakistan

blank

04

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Dextromethorphan; Diphenhydramine Hydrochloride

Dosage : SYRUP

Dosage Strength : 6.25MG; 5MG

Brand Name : Biollin-Dm

Approval Date :

Application Number :

Registration Country : Pakistan

blank

05

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Dextromethorphan; Diphenhydramine Hydrochloride

Brand Name : Depaxan

Dosage Form : SYRUP

Dosage Strength : 6.25MG; 5MG

Packaging : as per requirement

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Pakistan

blank

05

Bio Labs

Pakistan
BioFlorida Conference
Not Confirmed
arrow

Bio Labs

Pakistan
arrow
BioFlorida Conference
Not Confirmed

Dextromethorphan; Diphenhydramine Hydrochloride

Dosage : SYRUP

Dosage Strength : 6.25MG; 5MG

Brand Name : Depaxan

Approval Date :

Application Number :

Registration Country : Pakistan

blank

06

Hasco-Lek

Poland
BioFlorida Conference
Not Confirmed
arrow

Hasco-Lek

Poland
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride; Lidocaine Hydrochloride

Brand Name : Allefin

Dosage Form : Gel

Dosage Strength : 20; 10

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Poland

blank

06

Hasco-Lek

Poland
BioFlorida Conference
Not Confirmed
arrow

Hasco-Lek

Poland
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride; Lidocaine Hydrochloride

Dosage : Gel

Dosage Strength : 20; 10

Brand Name : Allefin

Approval Date :

Application Number :

Registration Country : Poland

blank

07

BioFlorida Conference
Not Confirmed
arrow
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride

Brand Name :

Dosage Form : Injection

Dosage Strength : 25mg/mL

Packaging : Glass Ampoule

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

blank

07

BioFlorida Conference
Not Confirmed
arrow
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride

Dosage : Injection

Dosage Strength : 25mg/mL

Brand Name :

Approval Date :

Application Number :

Registration Country : China

blank

08

Neopharma

U.A.E
BioFlorida Conference
Not Confirmed
arrow

Neopharma

U.A.E
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride

Brand Name : Neocoff

Dosage Form : Syrup

Dosage Strength : 14MG/5ML

Packaging : 125 ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : U.A.E

blank

08

Neopharma

U.A.E
BioFlorida Conference
Not Confirmed
arrow

Neopharma

U.A.E
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride

Dosage : Syrup

Dosage Strength : 14MG/5ML

Brand Name : Neocoff

Approval Date :

Application Number :

Registration Country : U.A.E

blank

09

BioFlorida Conference
Not Confirmed
arrow
arrow
BioFlorida Conference
Not Confirmed

Acetaminophen/Paracetamol; Phenylephrine; Diphenhydramine Hydrochloride

Brand Name :

Dosage Form : Granules

Dosage Strength : 650MG; 10MG; 25MG

Packaging : Sachet

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

blank

09

BioFlorida Conference
Not Confirmed
arrow
arrow
BioFlorida Conference
Not Confirmed

Acetaminophen/Paracetamol; Phenylephrine; Diphenhydramine Hydrochloride

Dosage : Granules

Dosage Strength : 650MG; 10MG; 25MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

10

Varsha Group

India
BioFlorida Conference
Not Confirmed
arrow

Varsha Group

India
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride; Bromhexine Hydrochloride; Ammonium Chloride; Sodium Citrate

Brand Name : V – COFEX

Dosage Form : Syrup

Dosage Strength : 8MG; 4MG; 100MG; 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

10

Varsha Group

India
BioFlorida Conference
Not Confirmed
arrow

Varsha Group

India
arrow
BioFlorida Conference
Not Confirmed

Diphenhydramine Hydrochloride; Bromhexine Hydrochloride; Ammonium Chloride; Sodium Citrate

Dosage : Syrup

Dosage Strength : 8MG; 4MG; 100MG; 50MG

Brand Name : V – COFEX

Approval Date :

Application Number :

Registration Country : India

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - CAPSULE;ORAL - 25MG;EQ 200MG FREE AC...DOSAGE - CAPSULE;ORAL - 25MG;EQ 200MG FREE ACID AND POTASSIUM SALT

USFDA APPLICATION NUMBER - 21393

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DOSAGE - INJECTABLE;INJECTION - 50MG/ML

USFDA APPLICATION NUMBER - 80817

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DOSAGE - ELIXIR;ORAL - 12.5MG/5ML

USFDA APPLICATION NUMBER - 87513

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