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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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EU WC

EU WC

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KDMF

KDMF

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VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

FDF DossiersDRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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PATENTS & EXCLUSIVITIES

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Health Canada Patents

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Finished Drug Prices

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0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:
Molecular Formula
C50H62CaF2O10
Molecular Weight
901.1  g/mol
InChI Key
KDDZXVQCHUXALQ-NIQIMLPHSA-L

Patiromer Sorbitex Calcium
1 2D Structure

Patiromer Sorbitex Calcium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
calcium;1,2-bis(ethenyl)benzene;1,3-bis(ethenyl)benzene;1,4-bis(ethenyl)benzene;2-fluoroprop-2-enoate;(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol;octa-1,7-diene
2.1.2 InChI
InChI=1S/3C10H10.C8H14.C6H14O6.2C3H3FO2.Ca/c1-3-9-5-7-10(4-2)8-6-9;1-3-9-6-5-7-10(4-2)8-9;1-3-9-7-5-6-8-10(9)4-2;1-3-5-7-8-6-4-2;7-1-3(9)5(11)6(12)4(10)2-8;2*1-2(4)3(5)6;/h3*3-8H,1-2H2;3-4H,1-2,5-8H2;3-12H,1-2H2;2*1H2,(H,5,6);/q;;;;;;;+2/p-2/t;;;;3-,4+,5-,6-;;;/m....1.../s1
2.1.3 InChI Key
KDDZXVQCHUXALQ-NIQIMLPHSA-L
2.1.4 Canonical SMILES
C=CCCCCC=C.C=CC1=CC=C(C=C1)C=C.C=CC1=CC(=CC=C1)C=C.C=CC1=CC=CC=C1C=C.C=C(C(=O)[O-])F.C=C(C(=O)[O-])F.C(C(C(C(C(CO)O)O)O)O)O.[Ca+2]
2.1.5 Isomeric SMILES
C=CCCCCC=C.C=CC1=CC=C(C=C1)C=C.C=CC1=CC(=CC=C1)C=C.C=CC1=CC=CC=C1C=C.C=C(C(=O)[O-])F.C=C(C(=O)[O-])F.C([C@H]([C@H]([C@@H]([C@H](CO)O)O)O)O)O.[Ca+2]
2.2 Create Date
2015-01-24
3 Chemical and Physical Properties
Molecular Weight 901.1 g/mol
Molecular Formula C50H62CaF2O10
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count12
Rotatable Bond Count16
Exact Mass900.3936953 g/mol
Monoisotopic Mass900.3936953 g/mol
Topological Polar Surface Area202 A^2
Heavy Atom Count63
Formal Charge0
Complexity556
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count8
4 Drug and Medication Information
4.1 Drug Information
1 of 1  
Drug NameVELTASSA
Active IngredientPATIROMER SORBITEX CALCIUM
CompanyRELYPSA INC (Application Number: N205739. Patents: 7556799, 8147873, 8216560, 8282913, 8287847, 8337824, 8475780, 8778324, 8889115, 9492476, 9925212)

DRUG PRODUCT COMPOSITIONS

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DOSAGE - POWDER;ORAL - EQ 16.8GM BASE/PACKET

USFDA APPLICATION NUMBER - 205739

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DOSAGE - POWDER;ORAL - EQ 1GM BASE/PACKET

USFDA APPLICATION NUMBER - 205739

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DOSAGE - POWDER;ORAL - EQ 25.2GM BASE/PACKET

USFDA APPLICATION NUMBER - 205739

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DOSAGE - POWDER;ORAL - EQ 8.4GM BASE/PACKET

USFDA APPLICATION NUMBER - 205739

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Market Place

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Patents & EXCLUSIVITIES

Check the patents & exclusivity for this product

US Patents

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01

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Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
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Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 11123363

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2033-10-08

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02

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 8475780

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2024-03-30

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03

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 9925212

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2033-10-08

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04

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 9492476

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2033-10-08

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05

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 8282913

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 205739

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2027-05-29

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06

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 8337824

Drug Substance Claim : Y

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2030-05-29

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07

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 8889115

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2024-03-30

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08

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 8216560

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2027-03-14

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09

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 10485821

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2024-03-30

blank

10

arrow
Antibody Engineering
Not Confirmed

VIFOR PHARMA

Switzerland
arrow
Antibody Engineering
Not Confirmed

PATIROMER SORBITEX CALCIUM

US Patent Number : 8216560

Drug Substance Claim :

Drug Product Claim :

Application Number : 205739

Patent Use Code : U-1766

Delist Requested :

Patent Use Description : TREATMENT OF HYPERKALE...

Patent Expiration Date : 2027-03-14

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