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ACTIVE PHARMA INGREDIENTS

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98 RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: Beta-d-galactopyranuronic acid, 18968-14-4, Beta-d-galacturonic acid, (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid, 55ng3o9ndd, Oligogalacturonide
Molecular Formula
C6H10O7
Molecular Weight
194.14  g/mol
InChI Key
AEMOLEFTQBMNLQ-DTEWXJGMSA-N
FDA UNII
55NG3O9NDD

Pectin
High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.
1 2D Structure

Pectin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2+,3+,4-,6+/m0/s1
2.1.3 InChI Key
AEMOLEFTQBMNLQ-DTEWXJGMSA-N
2.1.4 Canonical SMILES
C1(C(C(OC(C1O)O)C(=O)O)O)O
2.1.5 Isomeric SMILES
[C@@H]1([C@H]([C@H](O[C@H]([C@@H]1O)O)C(=O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
55NG3O9NDD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Calcium Pectinate

2. Methoxy Pectin

3. Methoxylpectin

4. Methoxypectin

5. Pectin, Methoxy

6. Pectinate, Calcium

7. Pectinate, Zinc

8. Pectinic Acid

9. Pectins

10. Zinc Pectinate

2.3.2 Depositor-Supplied Synonyms

1. Beta-d-galactopyranuronic Acid

2. 18968-14-4

3. Beta-d-galacturonic Acid

4. (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic Acid

5. 55ng3o9ndd

6. Oligogalacturonide

7. Unii-55ng3o9ndd

8. Schembl3407163

9. Chebi:47954

10. Galactopyranuronic Acid, Beta-d-

11. Zinc4097542

12. Db03652

13. .beta.-d-galactopyranuronic Acid

14. Galactopyranuronic Acid, .beta.-d-

15. C08348

16. Wurcs=2.0/1,1,0/[a2112a-1b_1-5]/1/

17. (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxytetrahydro-2h-pyran-2-carboxylic Acid

18. (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxytetrahydro-2h-pyran-2-carboxylicacid

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 194.14 g/mol
Molecular Formula C6H10O7
XLogP3-2.3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count1
Exact Mass194.04265265 g/mol
Monoisotopic Mass194.04265265 g/mol
Topological Polar Surface Area127 Ų
Heavy Atom Count13
Formal Charge0
Complexity205
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary fiber, lipid, cholesterol, serum glucose and insulin level lowering effect, gastric emptying delay. Some recent studies have researched the possibility of using pectin for the formation of nanoparticles as a delivery vehicle of drugs.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Pectin increases viscosity and volume of stools which helps it to be used for constipation and diarrhea. It is reported as well to present lowering effects of different body components. This effect depends on the type of pectin which indicated that this effect is related to the composition of the correspondent pectin. Nonetheless, this data is still unclear and more studies need to be performed to conclude this effect of pectin.


5.2 MeSH Pharmacological Classification

Food Additives

Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS. (See all compounds classified as Food Additives.)


5.3 ATC Code

A - Alimentary tract and metabolism

A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents

A07B - Intestinal adsorbents

A07BC - Other intestinal adsorbents

A07BC01 - Pectin


5.4 Absorption, Distribution and Excretion

Absorption

Pectin is not absorbed and it is not distributed in the body.


Route of Elimination

Pectin is completely excreted in the feces, including a small amount of trigalacturonic acid that can be found in the colon.


Volume of Distribution

Pharmacokinetic studies have not been performed as pectin is not absorbed.


Clearance

Pharmacokinetic studies have not been performed as pectin is not absorbed.


5.5 Metabolism/Metabolites

Pectin is depolymerized and de-esterified to a very small extent. It passes to the small intestine as a macromolecule and the majority of the pectin is eliminated unchanged.


5.6 Biological Half-Life

Pharmacokinetic studies have not been performed as pectin is not absorbed.


5.7 Mechanism of Action

Pectin is an adsorbent that binds to bacteria, toxins and other irritants in the intestinal mucosa. Pectin is able to decrease the pH in the intestinal lumen and provides a soothing effect on the irritated mucosa.


API SUPPLIERS

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USDMF

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Maple Biotech Pvt Ltd

India

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Pharma, Lab & Chemical Expo
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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 36058

Submission : 2021-07-10

Status : Active

Type : IV

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Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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Pectin

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.
Rochem

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pectin

About the Company : Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specia...

Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specializes in both biological and chemistry-based products and services. It has a strong track record in drug and product development, and supports development, optimization and testing of various compounds including proteins, monoclonal antibodies, peptides, large & small molecules and toxins. Inspected by USFDA, Japan’s PMDA, EU QPs, it develops nutritional products using organic synthesis and offers quality control and regulatory compliance assistance to clients.
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API Reference Price

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SAVLI,","city":"DIST VADODARA GUJARAT,GUJARAT","supplier":"JIANGXI HEALTHCARE IMPORT ","supplierCountry":"CHINA","foreign_port":"NA","customer":"BHARAT PARENTERALS LIMITED","customerCountry":"INDIA","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"90","totalValueFC":"6823.8","currency":"USD","unitRateINR":"7456.5","date":"11-Apr-2023","totalValueINR":"559237.5","totalValueInUsd":"6823.8","indian_port":"AHMEDABAD AIR","hs_no":"29412090","bill_no":"5458528","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SURVEY NO.144 & 146, VILLAGE,HARIP URA, TAL. SAVLI,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689618600,"product":"11501 ASCORBOSILANE C (AQUA ASCORBYL METHYLSILANOL PECTINATE, SODIUM METHYLPARABEN, ) (RAW MATERIAL FOR COSMETICS USE)","address":"M 10 SOUTH EXTENSION PART II,","city":"NEW DELHI,DELHI","supplier":"EXSYMOL MONACO","supplierCountry":"MONACO","foreign_port":"NA","customer":"ORIFLAME INDIA PRIVATE ","customerCountry":"INDIA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"60","totalValueFC":"2407.6","currency":"EUR","unitRateINR":"6595.7","date":"18-Jul-2023","totalValueINR":"197880.816","totalValueInUsd":"2407.6","indian_port":"DELHI AIR","hs_no":"29319090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"MONACO","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"M 10 SOUTH EXTENSION PART II,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1696271400,"product":"SPECTINOMYCIN SULFATE TETRAHYDRATE EP","address":"301 CEEJAY HOUSE LEVEL 3 SHIVSAGAR","city":"MUMBAI,MAHARASHTRA","supplier":"XXITEXXPHAXXA IXXUSTXXES XX LTX","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ARSHIYA LOGISTICS SERVICES LTD","customerCountry":"INDIA","quantity":"380.00","actualQuantity":"380","unit":"KGS","unitRateFc":"73.5","totalValueFC":"28205.4","currency":"USD","unitRateINR":"6177.7","date":"03-Oct-2023","totalValueINR":"2347517","totalValueInUsd":"28205.4","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29419090","bill_no":"1017221","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"301 CEEJAY HOUSE LEVEL 3 SHIVSAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710268200,"product":"SPECTINOMYCIN HYDROCHLORIDE SPCS: STERILE","address":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ","city":"AMRITSAR,PUNJAB","supplier":"M\/S. ZHEJIANG SHINDAI CHEMICALS CO. LTD","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"86","totalValueFC":"4337","currency":"USD","unitRateINR":"7202.5","date":"13-Mar-2024","totalValueINR":"360125","totalValueInUsd":"4337","indian_port":"Delhi Air","hs_no":"29339990","bill_no":"2555426","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"24A, NO.25 JUYE ROAD BINJIANGDISTRICT HANGZHOU CHINASDNF SDNF","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715797800,"product":"SPECTINOMYCIN HYDROCHLORIDE SPCS: STERILE","address":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ","city":"AMRITSAR,PUNJAB","supplier":"ZHEJIANG SHINDAI CHEMICALS ","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"86","totalValueFC":"4351.4","currency":"USD","unitRateINR":"7254.1","date":"16-May-2024","totalValueINR":"362705","totalValueInUsd":"4351.4","indian_port":"Delhi Air","hs_no":"29339990","bill_no":"3515339","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"24A, NO. 25 JUYE ROAD, BINJIANGDISTRICT HANGZHOU CHINASDNF SDNF","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723746600,"product":"SPECTINOMYCIN HYDROCHLORIDE USP","address":"SURVEY NO.144 146, VILLAGE","city":"DIST.VADODARA, GUJARAT","supplier":"JIANGXI HEALTHCARE IMPORT ","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"BHARAT PARENTERALS LIMITED","customerCountry":"INDIA","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"90","totalValueFC":"22760.6","currency":"USD","unitRateINR":"7636.5","date":"16-Aug-2024","totalValueINR":"1909125","totalValueInUsd":"22760.6","indian_port":"Ahmedabad Air","hs_no":"29412090","bill_no":"5093545","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"CO LTD. NO 156 BEIJING WEST ROAD,NANCHNANGSDNF CHINA","customerAddress":"SURVEY NO.144 146, VILLAGE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729621800,"product":"SPECTINOMYCIN HYDROCHLORIDE USP, BATCH: H152406011","address":"SURVEY NO.144 146, VILLAGE","city":"DIST.VADODARA, GUJARAT","supplier":"JIANGXI HEALTHCARE IMPORT ","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"BHARAT PARENTERALS LIMITED","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"90","totalValueFC":"13648.4","currency":"USD","unitRateINR":"7645.5","date":"23-Oct-2024","totalValueINR":"1146825","totalValueInUsd":"13648.4","indian_port":"Ahmedabad Air","hs_no":"29412090","bill_no":"6280685","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"CO LTD. NO 156 BEIJING WEST ROAD, NANCHNANG SDNF CHINA","customerAddress":"SURVEY NO.144 146, VILLAGE"}]
07-May-2021
23-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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Europe

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Duphat
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Dimethicone; Nifuroxazide; ATTAPULGITE; oligogalacturonide

Brand Name :

Dosage Form : ORAL SUSPENSION

Dosage Strength : 50MG; 60MG; 25MG; 100MG

Packaging : 120 Ml/Bottle

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Turkey

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Canada

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PECTIN

Brand Name : KAOLIN-PECTIN ORAL SUSPENSION

Dosage Form : SUSPENSION

Dosage Strength : 4.33MG/ML

Packaging : 4L

Approval Date :

Application Number : 2454009

Regulatory Info :

Registration Country : Canada

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02

Duphat
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PECTIN

Brand Name : SCOUR SUSPENSION

Dosage Form : SUSPENSION

Dosage Strength : 8MG/ML

Packaging : 240/250/400/500ML

Approval Date :

Application Number : 274895

Regulatory Info :

Registration Country : Canada

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03

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PECTIN

Brand Name : CALF SCOUR BOLUS

Dosage Form : BOLUS

Dosage Strength : 260MG/5G

Packaging : 25/50

Approval Date :

Application Number : 308390

Regulatory Info :

Registration Country : Canada

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04

CONVATEC CANADA LTD.

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Duphat
Not Confirmed
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CONVATEC CANADA LTD.

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Duphat
Not Confirmed

PECTIN

Brand Name : ORABASE PASTE

Dosage Form : PASTE

Dosage Strength : 13.3%

Packaging : 7.5G

Approval Date :

Application Number : 2035286

Regulatory Info :

Registration Country : Canada

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05

PARTNAR ANIMAL HEALTH INC.

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Duphat
Not Confirmed
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PARTNAR ANIMAL HEALTH INC.

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Not Confirmed

PECTIN

Brand Name : KAOLIN PECTIN SUSPENSION

Dosage Form : SUSPENSION

Dosage Strength : 4.53MG/ML

Packaging : 3.785L

Approval Date :

Application Number : 2303280

Regulatory Info :

Registration Country : Canada

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ABOUT THIS PAGE

Pectin Manufacturers

A Pectin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pectin, including repackagers and relabelers. The FDA regulates Pectin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pectin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Pectin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Pectin Suppliers

A Pectin supplier is an individual or a company that provides Pectin active pharmaceutical ingredient (API) or Pectin finished formulations upon request. The Pectin suppliers may include Pectin API manufacturers, exporters, distributors and traders.

click here to find a list of Pectin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Pectin USDMF

A Pectin DMF (Drug Master File) is a document detailing the whole manufacturing process of Pectin active pharmaceutical ingredient (API) in detail. Different forms of Pectin DMFs exist exist since differing nations have different regulations, such as Pectin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Pectin DMF submitted to regulatory agencies in the US is known as a USDMF. Pectin USDMF includes data on Pectin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Pectin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Pectin suppliers with USDMF on PharmaCompass.

Pectin GMP

Pectin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pectin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pectin GMP manufacturer or Pectin GMP API supplier for your needs.

Pectin CoA

A Pectin CoA (Certificate of Analysis) is a formal document that attests to Pectin's compliance with Pectin specifications and serves as a tool for batch-level quality control.

Pectin CoA mostly includes findings from lab analyses of a specific batch. For each Pectin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pectin may be tested according to a variety of international standards, such as European Pharmacopoeia (Pectin EP), Pectin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pectin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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