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    Chemistry

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    Also known as: Beta-d-galactopyranuronic acid, 18968-14-4, Beta-d-galacturonic acid, (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid, 55ng3o9ndd, Oligogalacturonide
    Molecular Formula
    C6H10O7
    Molecular Weight
    194.14  g/mol
    InChI Key
    AEMOLEFTQBMNLQ-DTEWXJGMSA-N
    FDA UNII
    55NG3O9NDD
    Pectin
    High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.
    1 2D Structure

    Pectin

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
    2.1.2 InChI
    InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2+,3+,4-,6+/m0/s1
    2.1.3 InChI Key
    AEMOLEFTQBMNLQ-DTEWXJGMSA-N
    2.1.4 Canonical SMILES
    C1(C(C(OC(C1O)O)C(=O)O)O)O
    2.1.5 Isomeric SMILES
    [C@@H]1([C@H]([C@H](O[C@H]([C@@H]1O)O)C(=O)O)O)O
    2.2 Other Identifiers
    2.2.1 UNII
    55NG3O9NDD
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Calcium Pectinate

    2. Methoxy Pectin

    3. Methoxylpectin

    4. Methoxypectin

    5. Pectin, Methoxy

    6. Pectinate, Calcium

    7. Pectinate, Zinc

    8. Pectinic Acid

    9. Pectins

    10. Zinc Pectinate

    2.3.2 Depositor-Supplied Synonyms

    1. Beta-d-galactopyranuronic Acid

    2. 18968-14-4

    3. Beta-d-galacturonic Acid

    4. (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic Acid

    5. 55ng3o9ndd

    6. Oligogalacturonide

    7. Unii-55ng3o9ndd

    8. Schembl3407163

    9. Chebi:47954

    10. Galactopyranuronic Acid, Beta-d-

    11. Zinc4097542

    12. Db03652

    13. .beta.-d-galactopyranuronic Acid

    14. Galactopyranuronic Acid, .beta.-d-

    15. C08348

    16. Wurcs=2.0/1,1,0/[a2112a-1b_1-5]/1/

    17. (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxytetrahydro-2h-pyran-2-carboxylic Acid

    18. (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxytetrahydro-2h-pyran-2-carboxylicacid

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 194.14 g/mol
    Molecular Formula C6H10O7
    XLogP3-2.3
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count1
    Exact Mass194.04265265 g/mol
    Monoisotopic Mass194.04265265 g/mol
    Topological Polar Surface Area127 Ų
    Heavy Atom Count13
    Formal Charge0
    Complexity205
    Isotope Atom Count0
    Defined Atom Stereocenter Count5
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary fiber, lipid, cholesterol, serum glucose and insulin level lowering effect, gastric emptying delay. Some recent studies have researched the possibility of using pectin for the formation of nanoparticles as a delivery vehicle of drugs.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Pectin increases viscosity and volume of stools which helps it to be used for constipation and diarrhea. It is reported as well to present lowering effects of different body components. This effect depends on the type of pectin which indicated that this effect is related to the composition of the correspondent pectin. Nonetheless, this data is still unclear and more studies need to be performed to conclude this effect of pectin.

    5.2 MeSH Pharmacological Classification

    Food Additives

    Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS. (See all compounds classified as Food Additives.)

    5.3 ATC Code

    A - Alimentary tract and metabolism

    A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents

    A07B - Intestinal adsorbents

    A07BC - Other intestinal adsorbents

    A07BC01 - Pectin

    5.4 Absorption, Distribution and Excretion

    Absorption

    Pectin is not absorbed and it is not distributed in the body.

    Route of Elimination

    Pectin is completely excreted in the feces, including a small amount of trigalacturonic acid that can be found in the colon.

    Volume of Distribution

    Pharmacokinetic studies have not been performed as pectin is not absorbed.

    Clearance

    Pharmacokinetic studies have not been performed as pectin is not absorbed.

    5.5 Metabolism/Metabolites

    Pectin is depolymerized and de-esterified to a very small extent. It passes to the small intestine as a macromolecule and the majority of the pectin is eliminated unchanged.

    5.6 Biological Half-Life

    Pharmacokinetic studies have not been performed as pectin is not absorbed.

    5.7 Mechanism of Action

    Pectin is an adsorbent that binds to bacteria, toxins and other irritants in the intestinal mucosa. Pectin is able to decrease the pH in the intestinal lumen and provides a soothing effect on the irritated mucosa.

    API Reference Price

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LTD","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"86","totalValueFC":"8698","currency":"USD","unitRateINR":"7340.1","date":"23-Nov-2024","totalValueINR":"734010","totalValueInUsd":"8698","indian_port":"Delhi Air","hs_no":"29339990","bill_no":"6840226","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"24A NO. 25 JUYE ROAD, BINJIANG DISTRICT HANGZHOU CHINA SDNF","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ"}]
    07-May-2021
    23-Nov-2024
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    ABOUT THIS PAGE

    Looking for 9000-69-5 / pectin API manufacturers, exporters & distributors?

    pectin manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of pectin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right pectin manufacturer or pectin supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred pectin manufacturer or pectin supplier.

    PharmaCompass also assists you with knowing the pectin API Price utilized in the formulation of products. pectin API Price is not always fixed or binding as the pectin Price is obtained through a variety of data sources. The pectin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    pectin

    Synonyms

    Beta-d-galactopyranuronic acid, 18968-14-4, Beta-d-galacturonic acid, (2s,3r,4s,5r,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid, 55ng3o9ndd, Oligogalacturonide

    Cas Number

    9000-69-5

    Unique Ingredient Identifier (UNII)

    55NG3O9NDD

    About pectin

    High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.

    Pectin Manufacturers

    A Pectin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pectin, including repackagers and relabelers. The FDA regulates Pectin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pectin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Pectin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Pectin Suppliers

    A Pectin supplier is an individual or a company that provides Pectin active pharmaceutical ingredient (API) or Pectin finished formulations upon request. The Pectin suppliers may include Pectin API manufacturers, exporters, distributors and traders.

    click here to find a list of Pectin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Pectin USDMF

    A Pectin DMF (Drug Master File) is a document detailing the whole manufacturing process of Pectin active pharmaceutical ingredient (API) in detail. Different forms of Pectin DMFs exist exist since differing nations have different regulations, such as Pectin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Pectin DMF submitted to regulatory agencies in the US is known as a USDMF. Pectin USDMF includes data on Pectin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Pectin USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Pectin suppliers with USDMF on PharmaCompass.

    Pectin GMP

    Pectin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Pectin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pectin GMP manufacturer or Pectin GMP API supplier for your needs.

    Pectin CoA

    A Pectin CoA (Certificate of Analysis) is a formal document that attests to Pectin's compliance with Pectin specifications and serves as a tool for batch-level quality control.

    Pectin CoA mostly includes findings from lab analyses of a specific batch. For each Pectin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Pectin may be tested according to a variety of international standards, such as European Pharmacopoeia (Pectin EP), Pectin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pectin USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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