DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Virtual Booth

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

7 Drugs in Development

7 Drugs in Development

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

7DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Pegsiticase, Pegadricase [usan:inn], Unii-50xb37ekn8, Uricase-peg 20, 50xb37ekn8, 1040753-26-1

Molecular Formula

C₁₃H₂₄N₂O₆

Molecular Weight

304.34 g/mol

InChI Key

PNFORBBPPMQASU-JTQLQIEISA-N

Pegadricase is under investigation in clinical trial NCT01021241 (Safety and Efficacy Study of Intravenous Uricase-PEG 20).

1 2D Structure

Pegadricase

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S)-2-amino-6-[[4-(2-methoxyethoxy)-4-oxobutanoyl]amino]hexanoic acid

2.1.2 InChI

InChI=1S/C13H24N2O6/c1-20-8-9-21-12(17)6-5-11(16)15-7-3-2-4-10(14)13(18)19/h10H,2-9,14H2,1H3,(H,15,16)(H,18,19)/t10-/m0/s1

2.1.3 InChI Key

PNFORBBPPMQASU-JTQLQIEISA-N

2.1.4 Canonical SMILES

COCCOC(=O)CCC(=O)NCCCCC(C(=O)O)N

2.1.5 Isomeric SMILES

COCCOC(=O)CCC(=O)NCCCC[C@@H](C(=O)O)N

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Pegsiticase

2. Pegadricase [usan:inn]

3. Unii-50xb37ekn8

4. Uricase-peg 20

5. 50xb37ekn8

6. 1040753-26-1

7. Q27260829

8. (198-threonine(s>t))uricase (ec 1.7.3.3, Urate Oxidase) Pichia Jadinii (yeast) (candida Utilis) Tetramer, Carbamates With Alpha-carboxy-omega-methoxypoly(oxyethylene)

9. Oxidase, Urate (synthetic Candida Utilis), Homotetramer, Compd. With Poly(oxy-1,2-ethanediyl)

2.3 Create Date

2014-11-22

3 Chemical and Physical Properties

Molecular Formula	C₁₃H₂₄N₂O₆
Molecular Weight	304.34 g/mol
XLogP3	-3.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	13
Exact Mass	304.16343649 g/mol
Monoisotopic Mass	304.16343649 g/mol
Topological Polar Surface Area	128 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	335
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1