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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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With Fermion, start the journey of your innovative API.

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Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

19 API Suppliers, 4 USDMF, 7 NDC API, 15 Listed Suppliers, $ API Reference Price

19 API Suppliers
4 USDMF
7 NDC API
15 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

103 Drugs in Development

103 Drugs in Development

INTERMEDIATES

16 Intermediates Suppliers

16 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

145 FDF Dossiers, 10 FDA Orange Book, 46 Europe, 10 Canada, 20 Australia, 17 South Africa, 42 Listed Dossiers

145 FDF Dossiers
10 FDA Orange Book
46 Europe
10 Canada
20 Australia
17 South Africa
42 Listed Dossiers

DIGITAL CONTENT

6 DATA COMPILATION #PharmaFlow, 114 NEWS #PharmaBuzz

media
6 DATA COMPILATION #PharmaFlow
114 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 40 Finished Drug Prices, 10 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
40 Finished Drug Prices
10 Annual Reports

MARKET PLACE

6 APIs, 14 FDF Dossiers, 1 Intermediates

marketPlace
6 APIs
14 FDF Dossiers
1 Intermediates

PATENTS & EXCLUSIVITIES

2 US Patents, 8 Health Canada Patents

patents
2 US Patents
8 Health Canada Patents

REF. STANDARDS & IMPURITIES

1 USP , 5 Others

otherSolutions
1 USP
5 Others

Rochem Pemetrexed popup

Synopsis

ACTIVE PHARMA INGREDIENTS

19

API Suppliers

4

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

0

EU WC

0

KDMF

7

NDC API

0

VMF

15

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 18,639

MARKET PLACE

6

API

14

FDF

16INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

145

FDF Dossiers

10

FDA Orange Book

FDA (Orange Book)

46

Europe

10

Canada

20

Australia

17

South Africa

42

Listed Dossiers

103DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

1

USP

0

JP

5

Others

PATENTS & EXCLUSIVITIES

2

US Patents

0

US Exclusivities

8

Health Canada Patents

DIGITAL CONTENT

6

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

114

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

7,434,149

Annual Reports (USD Million)

16,927

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:

Molecular Formula

C₂₀H₂₁N₅O₆

Molecular Weight

427.4 g/mol

InChI Key

WBXPDJSOTKVWSJ-CYBMUJFWSA-N

Pemetrexed

1 2D Structure

Pemetrexed

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

2.1.2 InChI

InChI=1S/C20H21N5O6/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29)/t13-/m1/s1

2.1.3 InChI Key

WBXPDJSOTKVWSJ-CYBMUJFWSA-N

2.1.4 Canonical SMILES

C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)O)C(=O)O

2.1.5 Isomeric SMILES

C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)N[C@H](CCC(=O)O)C(=O)O

2.2 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₁N₅O₆
Molecular Weight	427.4 g/mol
XLogP3	0.2
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	427.14918341 g/mol
Monoisotopic Mass	427.14918341 g/mol
Topological Polar Surface Area	187 A^2
Heavy Atom Count	31
Formal Charge	0
Complexity	748
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Alimta
PubMed Health	Pemetrexed (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Pemetrexed disodium heptahydrate has the chemical name L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C...
Active Ingredient	Pemetrexed; Pemetrexed disodium
Dosage Form	Injectable
Route	injection; Iv (infusion)
Strength	eq 500mg base/vial; 500mg; eq 100mg base/vial
Market Status	Prescription
Company	Lilly

2 of 2
Drug Name	Alimta
PubMed Health	Pemetrexed (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Pemetrexed disodium heptahydrate has the chemical name L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C...
Active Ingredient	Pemetrexed; Pemetrexed disodium
Dosage Form	Injectable
Route	injection; Iv (infusion)
Strength	eq 500mg base/vial; 500mg; eq 100mg base/vial
Market Status	Prescription
Company	Lilly

API SUPPLIERS

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API Reference Price

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REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"0.01","unit":"KGS","unitRateFc":"100324","totalValueFC":"1049.3","currency":"USD","unitRateINR":"7820349","date":"31-Jul-2021","totalValueINR":"78203.49","totalValueInUsd":"1049.3","indian_port":"BANGALORE AIR","hs_no":"29349990","bill_no":"4885177","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"7-1-27, AMEERPET"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1639938600,"product":"PEMETREXED DISODIUM (BATCH NO 1024P61C)","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"SHANDONG ANHONG PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"20657.1","totalValueFC":"147904.8","currency":"USD","unitRateINR":"1593698.6","date":"20-Dec-2021","totalValueINR":"11155890","totalValueInUsd":"147904.8","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29335990","bill_no":"1005068","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1656613800,"product":"PEMETREXED DISODIUM (HIOC-PMTR-C011-N) LOT NO 20220301 TO 20220307,20220401","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"CHEMWERTH INC","supplierCountry":"UNITED STATES","foreign_port":"N\/A","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"16.38","actualQuantity":"16378","unit":"GMS","unitRateFc":"16","totalValueFC":"260181","currency":"USD","unitRateINR":"1263.2","date":"01-Jul-2022","totalValueINR":"20688690","totalValueInUsd":"260181","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29419090","bill_no":"1002664","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"1764 LITCHFIELD TURNPIKE WOODBRIDGE CT 06525 UNITED STATES","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1659637800,"product":"PEMETREXED DISODIUM,BATCH NO 2015P61C & 2016P61C","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"SHANDONG ANHONG PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"9.00","actualQuantity":"9","unit":"KGS","unitRateFc":"25711.1","totalValueFC":"233385.9","currency":"USD","unitRateINR":"2063316.7","date":"05-Aug-2022","totalValueINR":"18569850","totalValueInUsd":"233385.9","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29335990","bill_no":"1003174","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667759400,"product":"PEMETREXED DISODIUM BATCH NO 2027P61C,2028P61C,2029P61C & 2030P61C","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"SHANDONG ANHONG PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"26000","totalValueFC":"533936.7","currency":"USD","unitRateINR":"2178800","date":"07-Nov-2022","totalValueINR":"43576000","totalValueInUsd":"533936.7","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29335990","bill_no":"1004590","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670956200,"product":"PEMETREXED DISODIUM HEPTAHYDRATE (BATCH NO. CL0120220101, CL0120220102) (PEMETREXED DISODIUM USP) (HEPTAHYDRATE\/HEMIPENT","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"ASUN LABORATORY LIMITED.","supplierCountry":"CHINA","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"13500","totalValueFC":"13433.4","currency":"USD","unitRateINR":"1107000","date":"14-Dec-2022","totalValueINR":"1107000","totalValueInUsd":"13433.4","indian_port":"BOMBAY AIR","hs_no":"29201990","bill_no":"3730715","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1686076200,"product":"(RE-IMPORT) PEMETREXED DISODIUM (HEMIPENTAHYDRATE) BULK DRUG(BATCH NO. PMDF220016#) (SB NO: 2163416\/16.06.22)","address":"","city":"","supplier":"NANG KUANG PHARMACEUTICAL CO., LTD","supplierCountry":"INDIA","foreign_port":"NA","customer":"SHILPA PHARMA LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"20000","totalValueFC":"144503.7","currency":"USD","unitRateINR":"1696809.3","date":"07-Jun-2023","totalValueINR":"11877664.53","totalValueInUsd":"144503.7","indian_port":"MADRAS AIR","hs_no":"29141990","bill_no":"0","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703788200,"product":"PEMETREXED DISODIUM","address":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ","city":"TAL- SANAND, DIST- AHMEDABAD","supplier":"XXANDXXG AXXONGXXHARXXCEUXXCALXXO.,XXTD","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"21000","totalValueFC":"84561.9","currency":"USD","unitRateINR":"1759800","date":"29-Dec-2023","totalValueINR":"7039200","totalValueInUsd":"84561.9","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29335990","bill_no":"1005250","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"PLOT NO. 3, PHARMEZ, SEZ, SARKEHJ"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721068200,"product":"PEMETREXED DISODIUM USP(HEPTAHYDRATE\/HEMIPENTAHYDRATE)(BATCHNO.CL0120230601)(PEMETREXED DISODIUM HEPTAHYDRATE)","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"ASUN LABORATORY LIMITED,","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"9000","totalValueFC":"4546.2","currency":"USD","unitRateINR":"760050","date":"16-Jul-2024","totalValueINR":"380025","totalValueInUsd":"4546.2","indian_port":"Bombay Air","hs_no":"29201990","bill_no":"4538430","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"18A LANCHESTER WAY, ROYAL OAK ESTATE INDUSTRIAL, DAVENTRY, NORTHAMPTONSHIRE, ENGLAND, NN11, 8P Daventry, United Kingdom","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729535400,"product":"PEMETREXED DISODIUM AMORPHOUS","address":"H.NO. 8-2-337, BESIDE TV9 OFFICE,,","city":"HYDERABAD,TELANGANA","supplier":"DR. REDDY\\'S LABORATORIES","supplierCountry":"INDIA","foreign_port":"VISAKHAPATNAM SEZ","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"0.01","unit":"KGS","unitRateFc":"11678.9","totalValueFC":"118.1","currency":"USD","unitRateINR":"992124","date":"22-Oct-2024","totalValueINR":"9921.24","totalValueInUsd":"118.1","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29339990","bill_no":"6265786","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"VISAKHAPATNAM SEZ","supplierAddress":"FTO -7, PLOT NO.P1 TO P9 V.S.E.Z., DUVVADA, VISAKHAPATNAM SDNF India","customerAddress":"H.NO. 8-2-337, BESIDE TV9 OFFICE,,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Finished Drug Prices

01

Brand Name : Pemetrexed Zentiva

France

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Sanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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France

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RX/OTC/DISCN : Class A

Helvepharm AG

Dosage Form : Inf Conc

Dosage Strength : 1000mg/40ml

Price Per Pack (Euro) : 851

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02

Brand Name : Pemetrexed Zentiva

France

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Sanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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France

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RX/OTC/DISCN : Class A

Helvepharm AG

Dosage Form : Inf Conc

Dosage Strength : 100mg/4ml

Price Per Pack (Euro) : 85.1

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Country : Switzerland

RX/OTC/DISCN : Class A

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03

Brand Name : Pemetrexed Zentiva

France

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France

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RX/OTC/DISCN : Class A

Helvepharm AG

Dosage Form : Inf Conc

Dosage Strength : 500mg/20ml

Price Per Pack (Euro) : 425.5

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Country : Switzerland

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Brand Name : Alimta

U.S.A

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Brand Name : Alimta

U.S.A

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06

Brand Name : Pemetrexed Accord liquid

United Kingdom

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07

Brand Name : Pemetrexed Accord liquid

United Kingdom

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08

Brand Name : Pemetrexed Accord liquid

United Kingdom

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09

Brand Name : Pemetrexed Sandoz conc.

Switzerland

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10

Brand Name : Pemetrexed Sandoz conc.

Switzerland

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