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ACTIVE PHARMA INGREDIENTS

37 API Suppliers, 33 USDMF, 2 CEP/COS, 2 JDMF, 2 NDC API, 1 VMF, 8 Listed Suppliers, $ API Reference Price

37 API Suppliers
33 USDMF
2 CEP/COS
2 JDMF
2 NDC API
1 VMF
8 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

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1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

107 FDF Dossiers, 78 FDA Orange Book, 15 Europe, 3 Canada, 6 Australia, 2 South Africa, 3 Listed Dossiers

107 FDF Dossiers
78 FDA Orange Book
15 Europe
3 Canada
6 Australia
2 South Africa
3 Listed Dossiers

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3 Actylis, 4 Roquette

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3 Parenteral, 2 Fillers, Diluents & Binders, 2 Controlled & Modified Release

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1 US Medicaid Prescriptions, 13 Finished Drug Prices, 1 Annual Reports

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13 Finished Drug Prices
1 Annual Reports

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9 APIs, 3 FDF Dossiers

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3 FDF Dossiers

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3 EDQM
1 USP

Synopsis

ACTIVE PHARMA INGREDIENTS

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API REF. PRICE (USD/KG)

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

107

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

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EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

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Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

1,084,681

Annual Reports (USD Million)

158

Finished Drug Prices

7EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 113-98-4, Benzylpenicillin potassium, Penicillin g potassium salt, Potassium benzylpenicillin, Potassium penicillin g, Benzylpenicillin potassium salt

Molecular Formula

C₁₆H₁₇KN₂O₄S

Molecular Weight

372.5 g/mol

InChI Key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

FDA UNII

VL775ZTH4C

A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.

1 2D Structure

Penicillin G Potassium

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

potassium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

2.1.2 InChI

InChI=1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

2.1.3 InChI Key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

2.1.4 Canonical SMILES

CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+]

2.1.5 Isomeric SMILES

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+]

2.2 Other Identifiers

2.2.1 UNII

VL775ZTH4C

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Benpen

2. Benzylpenicillin

3. Benzylpenicillin Potassium

4. Coliriocilina

5. Crystapen

6. Or-pen

7. Parcillin

8. Pekamin

9. Pengesod

10. Penibiot

11. Penicilina G Llorente

12. Penicillin G

13. Penicillin G Jenapharm

14. Penicillin G Sodium

15. Penicillin Grnenthal

16. Penilevel

17. Peniroger

18. Pfizerpen

19. Sodiopen

20. Sodipen

21. Sodium Benzylpenicillin

22. Sodium Penicillin

23. Unicilina

24. Ursopen

25. Van-pen-g

2.3.2 Depositor-Supplied Synonyms

1. 113-98-4

2. Benzylpenicillin Potassium

3. Penicillin G Potassium Salt

4. Potassium Benzylpenicillin

5. Potassium Penicillin G

6. Benzylpenicillin Potassium Salt

7. Penicillin G K

8. Pentids

9. Potassium Benzylpenicillinate

10. Pfizerpen

11. Benzylpenicilline Potassique

12. Potassium Salt Of Benzylpenicillin

13. Pfizerpen G

14. Penicillin-2

15. Notaral

16. Pentids '200'

17. Penicillin G (potassium)

18. Benzylpenicillinic Acid Potassium Salt

19. Chebi:7963

20. Penicilline G Potassium

21. Penicillin Potassium G, Crystalline

22. Falapen

23. Vl775zth4c

24. Penicillin G Potassium [usp]

25. Sk-penicillin G

26. Mls000069426

27. Potassium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

28. 6beta-phenylacetamidopenicillanic Acid Potassium Salt

29. Capicillin

30. Eskacillin

31. Hipercilina

32. Sugracillin

33. Cintrisul

34. Cristapen

35. Hyasorb

36. Hylenta

37. Lemopen

38. Liquapen

39. Monopen

40. Penalev

41. Penisem

42. Scotcil

43. Tabilin

44. Forpen

45. Pentid

46. Potassium;(2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

47. Smr000059004

48. Tu Cillin

49. C-cillin

50. Paclin G

51. Qidpen G

52. Megacillin Tablets

53. Potassium Benzylpenicillin G

54. Van-pen-g

55. Penicillin G Potassium (usp)

56. Penicilline G Potassium 100 Microg/ml In Acetonitrile/water

57. Novocillin Vet.

58. Potassium 6-(phenylacetamido)penicillanate

59. Monopotassium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate

60. Cilloral Potassium Salt

61. Cosmopen Potassium Salt

62. Nsc-131815

63. Unii-vl775zth4c

64. Penicilline

65. Pentids '250'

66. Pentids '400'

67. Pentids '800'

68. Benzylpenicilline Potassique [dcf]

69. Pfizerpen (tn)

70. Einecs 204-038-0

71. Mfcd00036193

72. Nsc 131815

73. Potassiumbenzylpenicillin

74. Opera_id_1649

75. Penicillin G Potassium In Plastic Container

76. Epitope Id:140781

77. Chembl1223

78. Dsstox_cid_25106

79. Dsstox_rid_80673

80. Dsstox_gsid_45106

81. Schembl34078

82. Mls001076462

83. Spectrum1500465

84. Dtxsid7045106

85. Hms500p18

86. Hms1920f12

87. Hms2091n12

88. Hms2234c21

89. Benzylpenicillin Potassium (jp17)

90. Bcp14289

91. Tox21_110044

92. Ccg-39599

93. Akos008145411

94. Penicillin G Potassium [vandf]

95. Cs-3873

96. Benzylpenicillin Potassium [jan]

97. Penicillin G Potassium [usp-rs]

98. Ncgc00014313-01

99. Penicillin G Potassium Salt [mi]

100. Ac-14408

101. As-75133

102. Benzylpenicillin Potassium [mart.]

103. Cas-113-98-4

104. E705

105. Hy-17591

106. Benzylpenicillin Potassium [who-dd]

107. Benzylpenicillin Potassium [who-ip]

108. Ai3-50119

109. Penicillin G Potassium [green Book]

110. Penicillin G Potassium Salt, ~1600 U/mg

111. P1772

112. Penicillin G Potassium [orange Book]

113. Penicillin G Potassium [usp Monograph]

114. D01053

115. Penicillin G Potassium Salt, Cell Culture Grade

116. Benzylpenicillin Potassium [ep Monograph]

117. Benzylpenicillinum Kalicum [who-ip Latin]

118. Penicillin G Potassium Salt, >=98.0% (hplc)

119. W-108609

120. Penicillin G Potassium 100 Microg/ml In Acetonitrile

121. Q27089370

122. Penicillin G Potassium Salt, Powder, Mouse Embryo Tested

123. Z803129904

124. Penicillin G Potassium Salt, Vetranal(tm), Analytical Standard

125. Penicillin G Potassium, Antibiotic For Culture Media Use Only

126. Benzylpenicillin Potassium, European Pharmacopoeia (ep) Reference Standard

127. Penicillin G Potassium Salt, Meets Usp Testing Specifications, Powder

128. Penicillin G Potassium Salt, Powder, Bioreagent, Suitable For Cell Culture

129. Penicillin G Potassium, United States Pharmacopeia (usp) Reference Standard

130. Potassium 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate

131. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6- (2-phenylacetamido)-, Monopotassium Salt

132. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((2-phenylacetyl)amino)- (2s,5r,6r)-, Potassium Salt (1:1)

133. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)- (2s,5r,6r)-, Monopotassium Salt

134. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-, Monopotassium Salt, (2s-(2.alpha.,5.alpha.,6.beta.))-

135. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-, Monopotassium Salt, (2s-(2alpha,5alpha,6beta))-

136. Potassium (2s-(2alpha,5alpha,6beta))-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	C₁₆H₁₇KN₂O₄S
Molecular Weight	372.5 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	372.05460969 g/mol
Monoisotopic Mass	372.05460969 g/mol
Topological Polar Surface Area	115 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	536
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Penicillin g potassium
Active Ingredient	Penicillin g potassium
Dosage Form	Injectable
Route	Injection
Strength	20,000,000 units/vial; 1,000,000 units/vial; 5,000,000 units/vial
Market Status	Prescription
Company	Istituto Bio Ita Spa; Sandoz; Hanford Gc

2 of 4
Drug Name	Penicillin g potassium in plastic container
PubMed Health	Penicillin G Potassium (Injection)
Drug Classes	Antibiotic
Drug Label	Penicillin G Potassium, USP is a natural penicillin. It is chemically designated 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, monopotassium salt, [2S-(2, 5, 6)]. Penicillin G potassium is...
Active Ingredient	Penicillin g potassium
Dosage Form	Injectable
Route	Injection
Strength	20,000 units/ml; 40,000 units/ml; 60,000 units/ml
Market Status	Prescription
Company	Baxter Hlthcare

3 of 4
Drug Name	Penicillin g potassium
Active Ingredient	Penicillin g potassium
Dosage Form	Injectable
Route	Injection
Strength	20,000,000 units/vial; 1,000,000 units/vial; 5,000,000 units/vial
Market Status	Prescription
Company	Istituto Bio Ita Spa; Sandoz; Hanford Gc

4 of 4
Drug Name	Penicillin g potassium in plastic container
PubMed Health	Penicillin G Potassium (Injection)
Drug Classes	Antibiotic
Drug Label	Penicillin G Potassium, USP is a natural penicillin. It is chemically designated 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, monopotassium salt, [2S-(2, 5, 6)]. Penicillin G potassium is...
Active Ingredient	Penicillin g potassium
Dosage Form	Injectable
Route	Injection
Strength	20,000 units/ml; 40,000 units/ml; 60,000 units/ml
Market Status	Prescription
Company	Baxter Hlthcare

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Penicillins [CS]; Penicillin-class Antibacterial [EPC]

API SUPPLIERS

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Listed Suppliers

01

Rochem International Inc

U.S.A

Suppliers Night Expo

Attending

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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U.S.A

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Penicillin G Potassium

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.

02

Centrient Pharmaceuticals

Netherlands

Antibody Engineering

Not Confirmed

Centrient is a leading manufacturer of Beta-Lactam Antibiotics and a provider of next-generation Statins and Antifungals.

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Netherlands

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Penicillin G Potassium

About the Company : Established in 1869, Centrient Pharmaceuticals is a global B2B leader in sustainable, enzymatic antibiotics, next-generation statins and anti-fungals. Together with tablets, capsul...

Established in 1869, Centrient Pharmaceuticals is a global B2B leader in sustainable, enzymatic antibiotics, next-generation statins and anti-fungals. Together with tablets, capsules and finished dosage forms, it manufactures and markets intermediates and active pharmaceutical ingredients (APIs). It is a pharmaceutical company with a clear purpose — to improve lives through innovative and sustainable manufacturing of medicines. Centrient is committed to ensuring quality, reliability and sustainability for its customers, partners and patients. Its vision is to be the leading, diversiﬁed and fully integrated partner for generics marketers.

03

ACS DOBFAR SPA

Italy

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Not Confirmed

04

ADL BioPharma

Spain

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Not Confirmed

05

Asia Pioneer Pharmaceuticals

U.S.A

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Not Confirmed

06

CSPC Pharmaceutical Group

China

Antibody Engineering

Not Confirmed

07

JIANGXI DONGFENG PHARMACEUTICAL LLC

China

Antibody Engineering

Not Confirmed

08

Sandoz B2B

Switzerland

Antibody Engineering

Not Confirmed

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API Reference Price

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