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Chemistry

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Also known as: Benzathine penicillin v, Benzathine phenoxymethylpenicillin, Penicillin v benzathine [usan:usp], 3t4emh59zu, (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid compound with n,n'-dibenzylethylenediamine (2:1), Biphecillin
Molecular Formula
C48H56N6O10S2
Molecular Weight
941.1  g/mol
InChI Key
BBTOYUUSUQNIIY-ANPZCEIESA-N
FDA UNII
3T4EMH59ZU

Penicillin V Benzathine
1 2D Structure

Penicillin V Benzathine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N,N'-dibenzylethane-1,2-diamine;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
2.1.2 InChI
InChI=1S/2C16H18N2O5S.C16H20N2/c2*1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h2*3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,17-18H,11-14H2/t2*11-,12+,14-;/m11./s1
2.1.3 InChI Key
BBTOYUUSUQNIIY-ANPZCEIESA-N
2.1.4 Canonical SMILES
CC1(C(N2C(S1)C(C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C.CC1(C(N2C(S1)C(C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C.C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2
2.1.5 Isomeric SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C.CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C.C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2
2.2 Other Identifiers
2.2.1 UNII
3T4EMH59ZU
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Benzathine Penicillin V

2. Bicillin-5

2.3.2 Depositor-Supplied Synonyms

1. Benzathine Penicillin V

2. Benzathine Phenoxymethylpenicillin

3. Penicillin V Benzathine [usan:usp]

4. 3t4emh59zu

5. (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid Compound With N,n'-dibenzylethylenediamine (2:1)

6. Biphecillin

7. Bicillin V

8. Bicillin-5

9. V-pen Ped Forte

10. Penicillin V Benzathine [usan]

11. Einecs 227-667-2

12. Unii-3t4emh59zu

13. Schembl418029

14. Penicillin V Benzathine (usp)

15. Chembl1396177

16. Dtxsid80207999

17. Ncgc00017051-01

18. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((2-phenoxyacetyl)amino)-, (2s-(2alpha,5alpha,6beta))-, Compd. With N,n'-bis(phenylmethyl)-1,2-ethanediamine (2:1)

19. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-, Compd. With N,n'-dibenzylethylenediamine (2:1)

20. Benzathine Phenoxymethyl Penicillin

21. N,n'-dibenzylethylenediammonium (2s-(2alpha,5alpha,6beta))-bis(3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate)

22. Penicillin Benzathine Phenoxymethyl

23. Cas-5928-84-7

24. Penicillin V Benzathine [usp Impurity]

25. D02405

26. 690p573

27. Benzathine Phenoxymethylpenicillin [mart.]

28. Phenoxymethylpenicillin Benzathine [who-dd]

29. Q4890751

30. Penicillin V Compd With Dibenzylethylenediamine

31. Penicillin V Compd With Dibenzylethylenediamine [mi]

32. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((2-phenoxyacetyl)amino)-, (2s,5r,6r)-, Compd. With N1,n2-bis(phenylmethyl)-1,2-ethanediamine (2:1)

33. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((2-phenoxyacetyl)amino)-, (2s-(2.alpha.,5.alpha.,6.beta.))-, Compd. With N,n'-bis(phenylmethyl)-1,2-ethanediamine (2:1)

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 941.1 g/mol
Molecular Formula C48H56N6O10S2
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count14
Rotatable Bond Count17
Exact Mass940.34993435 g/mol
Monoisotopic Mass940.34993435 g/mol
Topological Polar Surface Area267 Ų
Heavy Atom Count66
Formal Charge0
Complexity718
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01C - Beta-lactam antibacterials, penicillins

J01CE - Beta-lactamase sensitive penicillins

J01CE10 - Benzathine phenoxymethylpenicillin


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ABOUT THIS PAGE

Penicillin V Benzathine Manufacturers

A Penicillin V Benzathine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Penicillin V Benzathine, including repackagers and relabelers. The FDA regulates Penicillin V Benzathine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Penicillin V Benzathine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Penicillin V Benzathine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Penicillin V Benzathine Suppliers

A Penicillin V Benzathine supplier is an individual or a company that provides Penicillin V Benzathine active pharmaceutical ingredient (API) or Penicillin V Benzathine finished formulations upon request. The Penicillin V Benzathine suppliers may include Penicillin V Benzathine API manufacturers, exporters, distributors and traders.

click here to find a list of Penicillin V Benzathine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Penicillin V Benzathine GMP

Penicillin V Benzathine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Penicillin V Benzathine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Penicillin V Benzathine GMP manufacturer or Penicillin V Benzathine GMP API supplier for your needs.

Penicillin V Benzathine CoA

A Penicillin V Benzathine CoA (Certificate of Analysis) is a formal document that attests to Penicillin V Benzathine's compliance with Penicillin V Benzathine specifications and serves as a tool for batch-level quality control.

Penicillin V Benzathine CoA mostly includes findings from lab analyses of a specific batch. For each Penicillin V Benzathine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Penicillin V Benzathine may be tested according to a variety of international standards, such as European Pharmacopoeia (Penicillin V Benzathine EP), Penicillin V Benzathine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Penicillin V Benzathine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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