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1. Apocillin
2. Beromycin
3. Beromycin, Penicillin
4. Berromycin, Penicillin
5. Betapen
6. Fenoxymethylpenicillin
7. Pen Vk
8. Penicillin Beromycin
9. Penicillin Berromycin
10. Penicillin V
11. Penicillin V Sodium
12. Penicillin Vk
13. Penicillin, Phenoxymethyl
14. Phenoxymethyl Penicillin
15. Phenoxymethylpenicillin
16. Potassium, Penicillin V
17. Sodium, Penicillin V
18. V Cillin K
19. V Sodium, Penicillin
20. V-cillin K
21. Vcillin K
22. Vegacillin
1. Penicillin V Potassium Salt
2. 132-98-9
3. Penicillin Vk
4. Antibiocin
5. Phenoxymethylpenicillin Potassium
6. Beepen-vk
7. Potassium Penicillin V
8. Primcillin
9. Veetids
10. Ledercillin Vk
11. Pfizerpen Vk
12. Uticillin Vk
13. Betapen-vk
14. V-cillin K
15. Pen-vee K
16. Suspen
17. Penapar-vk
18. Penicillin-vk
19. Penicillin Potassium Phenoxymethyl
20. Beromycin
21. Vamosyn
22. Penicillin V (potassium)
23. 146t0tu1jb
24. Chebi:7967
25. Calciopen K
26. Phenoxymethylpenicillin Potassium Salt
27. Sk-penicillin Vk
28. Nsc-757258
29. Monopotassium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
30. Phenoxymethylpenicillinic Acid Potassium
31. Arcacil
32. Cliacil
33. Isocillin
34. Ispenoral
35. Kavepenin
36. Ospeneff
37. Pedipen
38. Penagen
39. Pencompren
40. Penvikal
41. Roscopenin
42. Icipen
43. Orapen
44. Megacillin Oral
45. Vepen
46. Compocillin-vk
47. Robicillin Vk
48. Dsstox_cid_1102
49. Veetids '125'
50. Veetids '250'
51. Veetids '500'
52. Rocillin-vk
53. Distaquaine V-k
54. Penapar Vk
55. Sumapen Vk
56. Distakaps V-k
57. Oracil-vk
58. Qidpen Vk
59. Apsin Vk
60. Aspin Vk
61. Dov-k
62. Dsstox_rid_75941
63. Dsstox_gsid_21102
64. Pen-v-k Powder
65. Dowpen V-k
66. Pen-vee-k Powder
67. Dqv-k
68. Potassium Penicillin V Salt
69. Pen Vk
70. V-cil-k
71. Beromycin (penicillin)
72. Potassium Phenoxymethylpenicillin
73. Potassium Phenoxymethyl Penicillin
74. Stabillin Vk Syrup 125
75. Phenoxymethylpenicillin Potassium (jan)
76. Stabillin Vk Syrup 62.5
77. Cas-132-98-9
78. Potassium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
79. Potassium (2s,5r,6r)-3,3-dimethyl-7-oxo-6-{[(phenyloxy)acetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
80. Ccris 750
81. Penicillin V Potassium [usan]
82. Phenoxymethylpenicillin Potassium [jan]
83. Hsdb 6315
84. Einecs 205-086-5
85. Mfcd00051771
86. Unii-146t0tu1jb
87. D-alpha-phenoxymethylpenicillinate K Salt
88. Potassium;(2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
89. Penicillin V Potassium [usan:usp]
90. Veetids (tn)
91. Penicilline V Potassium
92. Schembl41271
93. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-(( Phenoxyacetyl)amino)-, Monopotassium Salt, (2s-(2alpha,5alpha,6beta))-
94. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-(2 -phenoxyacetamido)-, Monopotassium Salt
95. Penicillinvpotassiumsalt
96. Spectrum1500467
97. Penicillin V Potassium (usp)
98. Chembl1200852
99. Dtxsid7021102
100. Hms502g21
101. Hms1920f14
102. Hms2091n14
103. Hy-b0975
104. Tox21_202176
105. Tox21_302914
106. Ccg-39570
107. Penicillin V Potassium [hsdb]
108. Phenoxymethylpenicillin Potassium,(s)
109. Akos024418766
110. Penicillin V Potassium [vandf]
111. Cs-4465
112. Nsc 757258
113. Mehyl-7-azaindole-4-carboxylate
114. Penicillin V Potassium [usp-rs]
115. Ncgc00164005-01
116. Ncgc00256459-01
117. Ncgc00259725-01
118. Penicillin Phenoxymethyl Potassium
119. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, Monopotassium Salt, (2s,5r,6r)-
120. As-83778
121. Penicillin V Potassium [green Book]
122. Penicillin V Potassium [orange Book]
123. Penicillin V Potassium [usp Impurity]
124. Penicillin V Potassium [usp Monograph]
125. C72320
126. D00497
127. Phenoxymethylpenicillin Potassium [mart.]
128. Penicilline V Potassium 100 Microg/ml In Methanol
129. Phenoxymethylpenicillin Potassium [who-dd]
130. Phenoxymethylpenicillin Potassium [who-ip]
131. W-109072
132. Q27107637
133. Phenoxymethylpenicillin Potassium [ep Monograph]
134. Phenoxymethylpenicillinum Kalicum [who-ip Latin]
135. Penicillin V Potassium Salt, Vetranal(tm), Analytical Standard
136. Penicillin V Potassium Salt, Powder, Bioreagent, Suitable For Cell Culture
137. Penicillin V Potassium, United States Pharmacopeia (usp) Reference Standard
138. Phenoxymethylpenicillin Potassium, Antibiotic For Culture Media Use Only
139. Phenoxymethylpenicillinic Acid Potassium Salt, Potency: >=1460 Units Per Mg
140. Potassium 2,2-dimethyl-6beta-(phenoxyacetamido)penam-3alpha-carboxylate
141. Phenoxymethylpenicillin Potassium, British Pharmacopoeia (bp) Reference Standard
142. Phenoxymethylpenicillin Potassium, European Pharmacopoeia (ep) Reference Standard
143. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((2-phenoxyacetyl)amino)-, Potassium Salt (1:1), (2s,5r,6r)-
144. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, Monopotassium Salt, (2s-(2.alpha.,5.alpha.,6.beta.))-
| Molecular Weight | 388.5 g/mol |
|---|---|
| Molecular Formula | C16H17KN2O5S |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 388.04952431 g/mol |
| Monoisotopic Mass | 388.04952431 g/mol |
| Topological Polar Surface Area | 124 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 553 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
| 1 of 2 | |
|---|---|
| Drug Name | Penicillin v potassium |
| Drug Label | Penicillin V is the phenoxymethyl analog of penicillin G. Penicillin V potassium is the potassium salt of penicillin V. Penicillin V Potassium is designated chemically as 4-Thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo- 6-[(... |
| Active Ingredient | Penicillin v potassium |
| Dosage Form | Tablet; For solution |
| Route | Oral |
| Strength | eq 250mg base/5ml; eq 500mg base; eq 250mg base; eq 125mg base/5ml |
| Market Status | Prescription |
| Company | Aurobindo Pharma; Sandoz; Hikma Pharms; Dava Pharms |
| 2 of 2 | |
|---|---|
| Drug Name | Penicillin v potassium |
| Drug Label | Penicillin V is the phenoxymethyl analog of penicillin G. Penicillin V potassium is the potassium salt of penicillin V. Penicillin V Potassium is designated chemically as 4-Thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo- 6-[(... |
| Active Ingredient | Penicillin v potassium |
| Dosage Form | Tablet; For solution |
| Route | Oral |
| Strength | eq 250mg base/5ml; eq 500mg base; eq 250mg base; eq 125mg base/5ml |
| Market Status | Prescription |
| Company | Aurobindo Pharma; Sandoz; Hikma Pharms; Dava Pharms |
Penicillins
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
Penicillin V /is/ indicated in the treatment of acute otitis media caused by susceptible organisms. /Included in US product labeling/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2149
Penicillin V /is/ indicated in the treatment of bacterial pharyngitis cuased by susceptible organisms. /Included in US product labeling/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2149
Penicillin V /is/ indicated in the treatment of sinusitis caused by susceptible organisms. /Included in US product labeling/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2150
For more Therapeutic Uses (Complete) data for PENICILLIN VK (18 total), please visit the HSDB record page.
Penicillins are distributed into breast milk, some in low concentrations. Although significant problems in humans have not been documented, the use of penicillins by nursing mothers may lead to sensitization, diarrhea, candidiasis, and skin rash in the infant. /Penicillins/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2151
Many penicillins have been used in pediatric patients and no pediatrics-specific problems have been documented to date. However, the incompletely developed renal function of neonates and young infants may delay the excretion of renally eliminated penicillins. /Penicillins/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2151
Penicillins have been used in geriatric patients and no geriatrics-specific problems have been documented to date. However, elderly patients are more likely to have age-related renal function impairment, which may require an adjustment in dosage in patients receiving penicillins. /Penicillins/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2151
Prolonged use of penicillins may lead to the development of oral candidiasis. /Penicillins/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2151
For more Drug Warnings (Complete) data for PENICILLIN VK (9 total), please visit the HSDB record page.
Anti-Bacterial Agents
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
A dose of 1,000,000 units of the acid gives peak plasma levels of about 2 to 3 ug/ml, but the potassium salt will provide levels of 4.5 to 9 ug/ml.
Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1142
Penicillin VK provides faster and higher blood levels of antibiotic than Penicillin V.
Osol A, Hoover JE et al (eds); Remington's Pharmaceutical Sciences. 14th ed. Easton, PA: Mack Publishing Co., p. 1230 (1975)
The half-life is 0.5 to 0.6 hr.
Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 1142
The penicillins and their metabolites are potent immunogens because of their ability to combine with proteins and act as haptens for acute antibody-mediated reactions. The most frequent (about 95 percent) or "major" determinant of penicillin allergy is the penicilloyl determinant produced by opening the beta-lactam ring of the penicillin. This allows linkage of the penicillin to protein at the amide group. "Minor" determinants (less frequent) are the other metabolites formed, including native penicillin and penicilloic acids. /Penicillins/
Haddad, L.M., Clinical Management of Poisoning and Drug Overdose. 2nd ed. Philadelphia, PA: W.B. Saunders Co., 1990., p. 953
Bactericidal; inhibit bacterial cell wall synthesis. Action is dependent on the ability of penicillins to reach and bind penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Penicillin-binding proteins (which include transpeptidases, carboxypeptidases, and endopeptidases) are enzymes that are involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Penicillins bind to, and inactivate, penicillin-binding proteins, resulting in the weakening of the bacterial cell wall and lysis. /Penicillins/
USP Convention. USPDI - Drug Information for the Health Care Professional. 15 th ed. Volume 1. Rockville, MD: United States Pharmacopeial Convention, Inc., 1995. (Plus updates.), p. 2150
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