List of Suppliers' Taste Masking Excipients Application used in PENTAZOCINE HYDROCHLORIDE on PharmaCompass.com

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ACTIVE PHARMA INGREDIENTS

9 API Suppliers, 5 USDMF, 2 JDMF, 3 NDC API, 4 Listed Suppliers, $ API Reference Price

9 API Suppliers
5 USDMF
2 JDMF
3 NDC API
4 Listed Suppliers
$ API Reference Price

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

22 FDF Dossiers, 10 FDA Orange Book, 1 Europe, 4 South Africa, 7 Listed Dossiers

22 FDF Dossiers
10 FDA Orange Book
1 Europe
4 South Africa
7 Listed Dossiers

RELATED EXCIPIENT COMPANIES

4 SPI Pharma, 1 DKSH, 1 Boai NKY Pharmaceuticals Ltd, 11 Gangwal Healthcare, 2 Actylis, 6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 16 BASF, 3 DFE Pharma, 6 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 4 Kerry, 10 Microlex e.U, 1 Novo Excipients, 3 Pharmatrans-Sanaq, 4 Pluviaendo, 3 Prachin Chemical, 19 Roquette, 1 Seppic, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 9 Sigachi Industries, 1 Ulanqab Kema New Material, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

43 Fillers, Diluents & Binders, 28 Direct Compression, 20 Disintegrants & Superdisintegrants, 17 Lubricants & Glidants, 16 Granulation, 15 Thickeners and Stabilizers, 12 Co-Processed Excipients, 10 Coating Systems & Additives, 9 Controlled & Modified Release, 7 Taste Masking, 7 Solubilizers, 6 Film Formers & Plasticizers, 5 Chewable & Orodispersible Aids, 4 Parenteral, 3 Emulsifying Agents, 2 Topical, 1 API Stability Enhancers, 1 Surfactant & Foaming Agents, 1 Rheology Modifiers

GLOBAL SALES INFORMATION

1 Finished Drug Prices

globalSalesInformation
1 Finished Drug Prices

MARKET PLACE

10 APIs, 1 FDF Dossiers

marketPlace
10 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 1,209

MARKET PLACE

API

FDF

1INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

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GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

115 RELATED EXCIPIENT COMPANIES

207EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 17146-95-1, Pentazocine lactate [usan], 1p2xib510o, (1r,9r,13r)-1,13-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;2-hydroxypropanoic acid, (2r*,6r*,11r*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol lactate (salt), Talwin (lactate)

Molecular Formula

C₂₂H₃₃NO₄

Molecular Weight

375.5 g/mol

InChI Key

QNLDTXPVZPRSAM-DTOXXUQYSA-N

FDA UNII

1P2XIB510O

The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)

1 2D Structure

Pentazocine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1R,9R,13R)-1,13-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;2-hydroxypropanoic acid

2.1.2 InChI

InChI=1S/C19H27NO.C3H6O3/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19;1-2(4)3(5)6/h5-7,12,14,18,21H,8-11H2,1-4H3;2,4H,1H3,(H,5,6)/t14-,18+,19+;/m0./s1

2.1.3 InChI Key

QNLDTXPVZPRSAM-DTOXXUQYSA-N

2.1.4 Canonical SMILES

CC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O.CC(C(=O)O)O

2.1.5 Isomeric SMILES

C[C@H]1[C@H]2CC3=C([C@@]1(CCN2CC=C(C)C)C)C=C(C=C3)O.CC(C(=O)O)O

2.2 Other Identifiers

2.2.1 UNII

1P2XIB510O

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Fortral

2. Hydrochloride, Pentazocine

3. Lactate, Pentazocine

4. Lexir

5. Pentazocine

6. Pentazocine Hydrochloride

7. Talwin

2.3.2 Depositor-Supplied Synonyms

1. 17146-95-1

2. Pentazocine Lactate [usan]

3. 1p2xib510o

4. (1r,9r,13r)-1,13-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol;2-hydroxypropanoic Acid

5. (2r*,6r*,11r*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol Lactate (salt)

6. Talwin (lactate)

7. Pentalgine

8. Talwin (as Lactate)

9. Unii-1p2xib510o

10. Talwin Injection

11. Einecs 241-209-9

12. Einecs 304-943-1

13. Talwin (tn)

14. Pentazocine Lactate (usp)

15. Schembl42094

16. (all-r)-pentazocine Dl-lactate

17. Chembl1200327

18. Pentazocine Lactate [mi]

19. Dtxsid101027503

20. Pentazocine Lactate [vandf]

21. Pentazocine Lactate [mart.]

22. Pentazocine Lactate [who-dd]

23. Pentazocine Lactate [green Book]

24. Pentazocine Lactate [orange Book]

25. 2-hydroxypropanoic Acid Compd. With (2alpha,6alpha,11r*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methanol-3-benzocin-8-ol (1:1)

26. Lactic Acid, Compd. With 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol (1:1)

27. Lactic Acid, Compound With (2alpha,6alpha,11r*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methylbut-2-enyl)-2,6-methano-3-benzocin-8-ol (1:1)

28. Pentazocine Lactate [ep Monograph]

29. D02111

30. Q27252701

31. 2,6-methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2.alpha.,6.alpha.,11r*)-, Compd. With 2-hydroxypropanoic Acid (1:1)

32. 2,6-methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2alpha,6alpha,11r*)-, Compd. With 2-hydroxypropanoic Acid (1:1)

33. Propanoic Acid, 2-hydroxy-, Compd. With (2alpha,6alpha,11r*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methanol-3-benzocin-8-ol (1:1)

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₃₃NO₄
Molecular Weight	375.5 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	375.24095853 g/mol
Monoisotopic Mass	375.24095853 g/mol
Topological Polar Surface Area	81 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	473
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Adjuvants, Anesthesia

Agents that are administered in association with anesthetics to increase effectiveness, improve delivery, or decrease required dosage. (See all compounds classified as Adjuvants, Anesthesia.)

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)

Narcotic Antagonists

Agents inhibiting the effect of narcotics on the central nervous system. (See all compounds classified as Narcotic Antagonists.)

Narcotics

Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)

API SUPPLIERS

01

Supriya Lifescience

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #1B18

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

F.I.S. Fabbrica Italiana Sintetici

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

03

F.I.S. Fabbrica Italiana Sintetici

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

04

Industriale Chimica

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

05

Mallinckrodt Pharmaceuticals

Ireland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

06

Olon S.p.A

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

07

Valence Labs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

08

Synthimed Labs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

09

CHEMO

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

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USDMF

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JDMF

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NDC API

01

F.I.S. FABBRICA ITALIANA SINTETICI ...

Italy

Discovery on Target

Not Confirmed

02

F.I.S. FABBRICA ITALIANA SINTETICI ...

Italy

Discovery on Target

Not Confirmed

03

Olon SpA

Italy

Discovery on Target

Not Confirmed

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Listed Suppliers

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API Reference Price

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N607200037 MFG.DT.","address":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,","city":"CHANDIGARH,CHANDIGARH","supplier":"IND SWIFT LABORATORIES LIMITED","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"JS BANK LIMITED CENTRALIZED CENTRAL","customerCountry":"PAKISTAN","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"1250","totalValueFC":"3651.4","currency":"USD","unitRateINR":99333.333333333328,"date":"03-Nov-2022","totalValueINR":"298000","totalValueInUsd":"3651.4","indian_port":"DELHI AIR","hs_no":"29333324","bill_no":"5221196","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"DELHI AIR","supplierAddress":"SCO.850, SHIVALIK ENCLAVE, NAC,,MA NIMAJRA,, CHANDIGARH,CHANDIGARH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671474600,"product":"PENTAZOCINE BATCH NO. 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FABBRICA ITALIANA SINTETICI","supplierCountry":"ITALY","foreign_port":"NA","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"210.00","actualQuantity":"210","unit":"KGS","unitRateFc":"2500","totalValueFC":"534464.3","currency":"USD","unitRateINR":"202375","date":"27-Jul-2022","totalValueINR":"42498750","totalValueInUsd":"534464.3","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"9750192","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"12TH FLOOR, COMMERZ II,,INTERNATIO NAL BUSNESS PARK,OBEROI"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

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Europe

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South Africa

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Excipients by Applications

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Fillers, Diluents & Binders

Direct Compression

Disintegrants & Superdisintegrants

Lubricants & Glidants

Granulation

Thickeners and Stabilizers

Co-Processed Excipients

Coating Systems & Additives

Controlled & Modified Release

Taste Masking

Solubilizers

Film Formers & Plasticizers

Chewable & Orodispersible Aids

Parenteral

Emulsifying Agents

Topical

API Stability Enhancers

Surfactant & Foaming Agents

Rheology Modifiers

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List of Suppliers' Taste Masking Excipients Application used in PENTAZOCINE HYDROCHLORIDE on PharmaCompass.com

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ACTIVE PHARMA INGREDIENTS

9 API Suppliers

5 USDMF

2 JDMF

3 NDC API

4 Listed Suppliers

$ API Reference Price

INTERMEDIATES

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

22 FDF Dossiers

10 FDA Orange Book

1 Europe

4 South Africa

7 Listed Dossiers

RELATED EXCIPIENT COMPANIES

4 SPI Pharma

1 DKSH

1 Boai NKY Pharmaceuticals Ltd

11 Gangwal Healthcare

2 Actylis

6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

16 BASF

3 DFE Pharma

6 Gangwal Chemicals

1 Ideal Cures Pvt Ltd

3 Ingredion Pharma Solutions

4 Kerry

10 Microlex e.U

1 Novo Excipients

3 Pharmatrans-Sanaq

4 Pluviaendo

3 Prachin Chemical

19 Roquette

1 Seppic

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

9 Sigachi Industries

1 Ulanqab Kema New Material

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

43 Fillers, Diluents & Binders

28 Direct Compression

20 Disintegrants & Superdisintegrants

17 Lubricants & Glidants

16 Granulation

15 Thickeners and Stabilizers

12 Co-Processed Excipients

10 Coating Systems & Additives

9 Controlled & Modified Release

7 Taste Masking

7 Solubilizers

6 Film Formers & Plasticizers

5 Chewable & Orodispersible Aids

4 Parenteral

3 Emulsifying Agents

2 Topical

1 API Stability Enhancers

1 Surfactant & Foaming Agents

1 Rheology Modifiers

GLOBAL SALES INFORMATION

1 Finished Drug Prices

MARKET PLACE

10 APIs

1 FDF Dossiers

REF. STANDARDS & IMPURITIES

1 USP

1 Others

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 1,209

MARKET PLACE

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES