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Chemistry

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Also known as: 14516-56-4, Perazine maleate, Perazine maleate [jan], Perazine maleate (jan), 3vg1507988, (z)-but-2-enedioic acid;10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
Molecular Formula
C28H33N3O8S
Molecular Weight
571.6  g/mol
InChI Key
PQDKNYWKLCFCJU-SPIKMXEPSA-N
FDA UNII
3VG1507988

Perazine Maleate
A phenothiazine antipsychotic with actions and uses similar to those of CHLORPROMAZINE. Extrapyramidal symptoms may be more common than other side effects.
1 2D Structure

Perazine Maleate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(Z)-but-2-enedioic acid;10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
2.1.2 InChI
InChI=1S/C20H25N3S.2C4H4O4/c1-21-13-15-22(16-14-21)11-6-12-23-17-7-2-4-9-19(17)24-20-10-5-3-8-18(20)23;2*5-3(6)1-2-4(7)8/h2-5,7-10H,6,11-16H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
2.1.3 InChI Key
PQDKNYWKLCFCJU-SPIKMXEPSA-N
2.1.4 Canonical SMILES
CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=CC=CC=C42.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
2.1.5 Isomeric SMILES
CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=CC=CC=C24.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O
2.2 Other Identifiers
2.2.1 UNII
3VG1507988
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Dihydrochloride, Perazine

2. Maleate, Perazine

3. Perazine

4. Perazine Dihydrochloride

5. Perazine Maleate

6. Perazine Maleate (1:1)

7. Perazine Maleate (1:2)

8. Pernazine

9. Taxilan

2.3.2 Depositor-Supplied Synonyms

1. 14516-56-4

2. Perazine Maleate

3. Perazine Maleate [jan]

4. Perazine Maleate (jan)

5. 3vg1507988

6. (z)-but-2-enedioic Acid;10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine

7. Unii-3vg1507988

8. Chebi:31979

9. Perazine Dimaleate [who-dd]

10. D01412

11. Q27258087

12. Perazine Dimaleate 1.0 Mg/ml In Dimethyl Sulfoxide (as Free Base)

13. 10h-phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-, (z)-2-butenedioate (1:2)

14. Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-, Maleate (1:2)

2.4 Create Date
2005-10-11
3 Chemical and Physical Properties
Molecular Weight 571.6 g/mol
Molecular Formula C28H33N3O8S
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count12
Rotatable Bond Count8
Exact Mass571.19883619 g/mol
Monoisotopic Mass571.19883619 g/mol
Topological Polar Surface Area184 Ų
Heavy Atom Count40
Formal Charge0
Complexity493
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


Dopamine Antagonists

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)


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10-Mar-2021
08-Jan-2025
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ABOUT THIS PAGE

Looking for 14516-56-4 / Perazine Maleate API manufacturers, exporters & distributors?

Perazine Maleate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Perazine Maleate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Perazine Maleate manufacturer or Perazine Maleate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Perazine Maleate manufacturer or Perazine Maleate supplier.

PharmaCompass also assists you with knowing the Perazine Maleate API Price utilized in the formulation of products. Perazine Maleate API Price is not always fixed or binding as the Perazine Maleate Price is obtained through a variety of data sources. The Perazine Maleate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Perazine Maleate

Synonyms

14516-56-4, Perazine maleate [jan], Perazine maleate (jan), 3vg1507988, (z)-but-2-enedioic acid;10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine, Unii-3vg1507988

Cas Number

14516-56-4

Unique Ingredient Identifier (UNII)

3VG1507988

About Perazine Maleate

A phenothiazine antipsychotic with actions and uses similar to those of CHLORPROMAZINE. Extrapyramidal symptoms may be more common than other side effects.

Perazine Maleate Manufacturers

A Perazine Maleate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Perazine Maleate, including repackagers and relabelers. The FDA regulates Perazine Maleate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Perazine Maleate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Perazine Maleate Suppliers

A Perazine Maleate supplier is an individual or a company that provides Perazine Maleate active pharmaceutical ingredient (API) or Perazine Maleate finished formulations upon request. The Perazine Maleate suppliers may include Perazine Maleate API manufacturers, exporters, distributors and traders.

click here to find a list of Perazine Maleate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Perazine Maleate WC

A Perazine Maleate written confirmation (Perazine Maleate WC) is an official document issued by a regulatory agency to a Perazine Maleate manufacturer, verifying that the manufacturing facility of a Perazine Maleate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Perazine Maleate APIs or Perazine Maleate finished pharmaceutical products to another nation, regulatory agencies frequently require a Perazine Maleate WC (written confirmation) as part of the regulatory process.

click here to find a list of Perazine Maleate suppliers with Written Confirmation (WC) on PharmaCompass.

Perazine Maleate GMP

Perazine Maleate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Perazine Maleate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Perazine Maleate GMP manufacturer or Perazine Maleate GMP API supplier for your needs.

Perazine Maleate CoA

A Perazine Maleate CoA (Certificate of Analysis) is a formal document that attests to Perazine Maleate's compliance with Perazine Maleate specifications and serves as a tool for batch-level quality control.

Perazine Maleate CoA mostly includes findings from lab analyses of a specific batch. For each Perazine Maleate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Perazine Maleate may be tested according to a variety of international standards, such as European Pharmacopoeia (Perazine Maleate EP), Perazine Maleate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Perazine Maleate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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