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1. D 21266
2. D-21266
3. Octadecyl-(1,1-dimethyl-4-piperidylio)phosphate
1. 157716-52-4
2. Krx-0401
3. 1,1-dimethylpiperidin-1-ium-4-yl Octadecyl Phosphate
4. Perifosine (krx-0401)
5. (1,1-dimethylpiperidin-1-ium-4-yl) Octadecyl Phosphate
6. Nsc 639966
7. Perifosine [inn]
8. D 21266
9. Nsc-639966
10. 1,1-dimethylpiperidinium-4-yl Octadecyl Phosphate
11. Krx 0401
12. Nsc639966
13. D-21266
14. Chebi:67272
15. 2gwv496552
16. Ncgc00187909-01
17. Piperidinium, 4-[[hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethyl-, Inner Salt
18. 1,1-dimethylpiperidin-1-ium-4-yl Octadecyl Phosphate.
19. Piperidinium, 4-((hydroxy(octadecyloxy)phosphinyl)oxy)-1,1-dimethyl-, Inner Salt
20. Nka17
21. Unii-2gwv496552
22. Octadecyl-(1,1-dimethyl-4-piperidylio)phosphate
23. 4-((hydroxy(octadecyloxy)phosphinyl)oxy)-1,1-dimethylpiperidinium Inner Salt
24. Perifosine [mi]
25. Dsstox_cid_28872
26. Dsstox_rid_83141
27. Perifosine [who-dd]
28. Dsstox_gsid_48946
29. Schembl93872
30. Chembl372764
31. Gtpl7424
32. Dtxsid3048946
33. Bcp00245
34. Ex-a2229
35. Yhi-1003
36. Tox21_113365
37. Bdbm50431630
38. Mfcd00927554
39. Nsc800842
40. S1037
41. Piperidinium,1-dimethyl-, Inner Salt
42. Akos005146344
43. Ccg-269358
44. Cs-0209
45. Db06641
46. Ex-3388
47. Gs-3834
48. Nsc-800842
49. Ncgc00187909-02
50. Ncgc00187909-13
51. Ac-25019
52. Am808092
53. Hy-50909
54. Cas-157716-52-4
55. Ft-0651459
56. P2831
57. A23834
58. D21266
59. Octadecyl-(1,1-dimethyl-4-piperidylio) Phosphate
60. J-500086
61. Q3411917
62. Perifosine; Krx-0401; Nsc 639966; D21266
63. 1,1-dimethylpiperidinium-4-yl Octadecyl Phosphate, Inner Salt
64. 4-hydroxy-1,1-dimethylpiperidinium Hydroxide, Octadecyl Hydrogen Phosphate, Inner Salt
| Molecular Weight | 461.7 g/mol |
|---|---|
| Molecular Formula | C25H52NO4P |
| XLogP3 | 8.3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 20 |
| Exact Mass | 461.36339614 g/mol |
| Monoisotopic Mass | 461.36339614 g/mol |
| Topological Polar Surface Area | 58.6 Ų |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 454 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in solid tumors, multiple myeloma, leukemia (unspecified), lung cancer, and brain cancer.
Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis.
ABOUT THIS PAGE
A Perifosine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Perifosine, including repackagers and relabelers. The FDA regulates Perifosine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Perifosine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Perifosine supplier is an individual or a company that provides Perifosine active pharmaceutical ingredient (API) or Perifosine finished formulations upon request. The Perifosine suppliers may include Perifosine API manufacturers, exporters, distributors and traders.
click here to find a list of Perifosine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Perifosine DMF (Drug Master File) is a document detailing the whole manufacturing process of Perifosine active pharmaceutical ingredient (API) in detail. Different forms of Perifosine DMFs exist exist since differing nations have different regulations, such as Perifosine USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Perifosine DMF submitted to regulatory agencies in the US is known as a USDMF. Perifosine USDMF includes data on Perifosine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Perifosine USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Perifosine suppliers with USDMF on PharmaCompass.
Perifosine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Perifosine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Perifosine GMP manufacturer or Perifosine GMP API supplier for your needs.
A Perifosine CoA (Certificate of Analysis) is a formal document that attests to Perifosine's compliance with Perifosine specifications and serves as a tool for batch-level quality control.
Perifosine CoA mostly includes findings from lab analyses of a specific batch. For each Perifosine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Perifosine may be tested according to a variety of international standards, such as European Pharmacopoeia (Perifosine EP), Perifosine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Perifosine USP).
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